| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | transcription factor 4|This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 6925) |
| External Link | https://ncbi.nlm.nih.gov/gene/6925 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the TCF4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 0.0178564 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0132367 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0132175 |
| CA2 | carbonic anhydrase II | 0.0128923 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0126454 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0122885 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0117707 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0116649 |
| ADM | adrenomedullin | 0.0114087 |
| ITM2C | integral membrane protein 2C | 0.0113971 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.01139 |
| MAL | mal, T-cell differentiation protein | 0.0113056 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.0112719 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0109145 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0107081 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.0103451 |
| ATF3 | activating transcription factor 3 | 0.0101617 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0100752 |
| ABLIM1 | actin binding LIM protein 1 | 0.00997103 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00987006 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00982418 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00970964 |
| S100A10 | S100 calcium binding protein A10 | 0.00969361 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00965976 |
| KLF6 | Kruppel-like factor 6 | 0.0096397 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00962954 |
| BEX4 | brain expressed, X-linked 4 | 0.00961763 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00950102 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00922951 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00918651 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00904535 |
| NVL | nuclear VCP-like | 0.00901684 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00900365 |
| ODC1 | ornithine decarboxylase 1 | 0.00886601 |
| ASS1 | argininosuccinate synthase 1 | 0.00881187 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00878536 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00871389 |
| IER3 | immediate early response 3 | 0.00870468 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00866452 |
| PITX3 | paired-like homeodomain 3 | 0.00861448 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0085547 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00855222 |
| EGR3 | early growth response 3 | 0.00848961 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.0084886 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00833908 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00833314 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00831498 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00826889 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00807399 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.0079799 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00796096 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00794506 |
| RCAN1 | regulator of calcineurin 1 | 0.00790786 |
| CLTB | clathrin, light chain B | 0.0078449 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.0078242 |
| MVP | major vault protein | 0.00782311 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00780425 |
| HMOX1 | heme oxygenase 1 | 0.00778177 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.0077726 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00776351 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00776242 |
| GOLT1B | golgi transport 1B | 0.00774792 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00772403 |
| WDR61 | WD repeat domain 61 | 0.00772191 |
| DDT | D-dopachrome tautomerase | 0.00771561 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00766111 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00765892 |
| TFRC | transferrin receptor | 0.00765443 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00763618 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00758172 |
| CA12 | carbonic anhydrase XII | 0.00757833 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00756709 |
| BMP2 | bone morphogenetic protein 2 | 0.00756573 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00756044 |
| ANXA2 | annexin A2 | 0.00755456 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00751591 |
| PYCARD | PYD and CARD domain containing | 0.00748504 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.007457 |
| CD9 | CD9 molecule | 0.00745381 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00745114 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00744336 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0074292 |
| E2F2 | E2F transcription factor 2 | 0.00737415 |
| KRT20 | keratin 20, type I | 0.00733202 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00732457 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00727674 |
| CST1 | cystatin SN | 0.00724349 |
| S100A14 | S100 calcium binding protein A14 | 0.00722852 |
| MEN1 | multiple endocrine neoplasia I | 0.00722348 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00719178 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00717548 |
| XIC | X chromosome inactivation center | 0.00717362 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00714841 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00713237 |
| BLNK | B-cell linker | 0.00712164 |
| PSAP | prosaposin | 0.00711062 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00709999 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00708826 |
| DEFB1 | defensin, beta 1 | 0.00703534 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00702994 |
| CLDN7 | claudin 7 | 0.00701781 |
| H1-2 | H1.2 linker histone, cluster member | 0.00700237 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00699221 |
| JUP | junction plakoglobin | 0.00695063 |
| PXDC1 | PX domain containing 1 | 0.0069205 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00689874 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00683441 |
| ZG16 | zymogen granule protein 16 | 0.00683077 |
| EGR1 | early growth response 1 | 0.00680079 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00678652 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00676794 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00676345 |
| PROM1 | prominin 1 | 0.00674822 |
| ENOPH1 | enolase-phosphatase 1 | 0.00674452 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00671508 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00668613 |
| RMDN1 | regulator of microtubule dynamics 1 | 0.00664954 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00664236 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00662987 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00662593 |
| SMAD3 | SMAD family member 3 | 0.00659053 |
| ACP1 | acid phosphatase 1, soluble | 0.00657309 |
| MOSPD1 | motile sperm domain containing 1 | 0.0065339 |
| RPL36 | ribosomal protein L36 | 0.00652643 |
| YBX3 | Y box binding protein 3 | 0.00649853 |
| CTSD | cathepsin D | 0.00648134 |
| VDAC2 | voltage-dependent anion channel 2 | 0.0064633 |
| TRIB3 | tribbles pseudokinase 3 | 0.00645241 |
| CD52 | CD52 molecule | 0.0064316 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00643127 |
| DNTT | DNA nucleotidylexotransferase | 0.00640722 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | 0.00640295 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00640275 |
| RETREG1 | reticulophagy regulator 1 | 0.00639322 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | 0.00638766 |
| REG1A | regenerating islet-derived 1 alpha | 0.00637713 |
| AHCY | adenosylhomocysteinase | 0.00636544 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00635237 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 0.00634183 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00632434 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00632094 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | 0.00631859 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00629777 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00629541 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00628805 |
| TRAPPC2L | trafficking protein particle complex 2-like | 0.00628237 |
| R3HDM4 | R3H domain containing 4 | 0.00627787 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.00627748 |
| SMAGP | small cell adhesion glycoprotein | 0.00627329 |
| LIAS | lipoic acid synthetase | 0.00626354 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.00625054 |
| JUNB | jun B proto-oncogene | 0.00624982 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00623625 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00621457 |
| CLCA1 | chloride channel accessory 1 | 0.00620922 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0061965 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00618871 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.00618161 |
| RPL14 | ribosomal protein L14 | 0.00616962 |
| SGCE | sarcoglycan, epsilon | 0.00616486 |
| RPS27L | ribosomal protein S27-like | 0.00615817 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00613883 |
| LEFTY1 | left-right determination factor 1 | 0.00613657 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00613388 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00612844 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00612575 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00612293 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0061165 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00611598 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00611156 |
| PXDN | peroxidasin | 0.00610231 |
| EVI2A | ecotropic viral integration site 2A | 0.00609377 |
| ORC4 | origin recognition complex, subunit 4 | 0.00608452 |
| TEX10 | testis expressed 10 | 0.00606966 |
| NRCAM | neuronal cell adhesion molecule | 0.00606683 |
| MXD4 | MAX dimerization protein 4 | 0.00606493 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00605915 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00604786 |
| MRPS10 | mitochondrial ribosomal protein S10 | 0.00604633 |
| TMEM14B | transmembrane protein 14B | 0.00604395 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00603132 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00600064 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00599081 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00596438 |
| RNASET2 | ribonuclease T2 | 0.00595772 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00594365 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00593334 |
| SST | somatostatin | 0.00593229 |
| LPIN1 | lipin 1 | 0.00592636 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00590691 |
| STMN2 | stathmin 2 | 0.0059059 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00590305 |
| CAB39 | calcium binding protein 39 | 0.0059017 |
| RIOK3 | RIO kinase 3 | 0.00589812 |
| GDF15 | growth differentiation factor 15 | 0.00588733 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00587775 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.00587733 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00587274 |
| PEG10 | paternally expressed 10 | 0.0058679 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00586704 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00584071 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00583931 |
| NDRG4 | NDRG family member 4 | 0.00582538 |
| SELENOW | selenoprotein W | 0.00582356 |
| GUK1 | guanylate kinase 1 | 0.00582234 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00581656 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.00580593 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00580464 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00580294 |
| RRAGD | Ras-related GTP binding D | 0.00579497 |
| LYRM4 | LYR motif containing 4 | 0.00579373 |
| HEBP2 | heme binding protein 2 | 0.00579233 |
| EZR | ezrin | 0.00577916 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00577428 |
| NPTX2 | neuronal pentraxin II | 0.00577084 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00574841 |
| TPRKB | TP53RK binding protein | 0.00572538 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00570705 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0057065 |
| KRT19 | keratin 19, type I | 0.00569938 |
| PRSS3 | protease, serine, 3 | 0.00569075 |
| LIF | leukemia inhibitory factor | 0.00568832 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00566556 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00565882 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | 0.00565575 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.00563857 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00562277 |
| RHCG | Rh family, C glycoprotein | 0.00562157 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00561892 |
| MCL1 | myeloid cell leukemia 1 | 0.00559679 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00559097 |
| AKIRIN1 | akirin 1 | 0.00558653 |
| GLRX5 | glutaredoxin 5 | 0.00558005 |
| ZNF721 | zinc finger protein 721 | 0.00556933 |
| INHBA | inhibin, beta A | 0.00555334 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00555311 |
| FOSL1 | FOS-like antigen 1 | 0.00554809 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00553795 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0055362 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0055304 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00550677 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00549928 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00549817 |
| COX5B | cytochrome c oxidase subunit Vb | 0.00548472 |
| MRPS18A | mitochondrial ribosomal protein S18A | 0.00548029 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00547487 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00546658 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00545512 |
| TES | testin LIM domain protein | 0.0054507 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | 0.00543352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0305184 |
| KIF20A | kinesin family member 20A | -0.0164151 |
| TYMS | thymidylate synthetase | -0.0137266 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.0136864 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.0134272 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0132777 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0131357 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0123028 |
| LTF | lactotransferrin | -0.0118867 |
| MMP7 | matrix metallopeptidase 7 | -0.0118382 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.011776 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.0114828 |
| NFIB | nuclear factor I/B | -0.011384 |
| FEN1 | flap structure-specific endonuclease 1 | -0.0113641 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0112915 |
| KRT17 | keratin 17, type I | -0.0112605 |
| AGTR1 | angiotensin II receptor, type 1 | -0.0110982 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0110978 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0109729 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0107077 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0106903 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0106703 |
| CP | ceruloplasmin (ferroxidase) | -0.0104805 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0104406 |
| DMD | dystrophin | -0.0104285 |
| GAS1 | growth arrest-specific 1 | -0.0103911 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0102798 |
| MPZL2 | myelin protein zero-like 2 | -0.00990461 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00988975 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00984151 |
| CHRDL1 | chordin-like 1 | -0.00975305 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00973473 |
| BCHE | butyrylcholinesterase | -0.00966892 |
| RBPMS | RNA binding protein with multiple splicing | -0.00964365 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0096252 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00950332 |
| FBLN1 | fibulin 1 | -0.00946229 |
| MGP | matrix Gla protein | -0.00928761 |
| GOLM1 | golgi membrane protein 1 | -0.00925506 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00922532 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00919085 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00913694 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0091287 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.0091224 |
| DHFR | dihydrofolate reductase | -0.00905999 |
| PIP | prolactin-induced protein | -0.00905728 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00904455 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0089176 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00883635 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00881753 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00877434 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00877339 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00873205 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00871244 |
| C5AR1 | complement component 5a receptor 1 | -0.00870805 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00870041 |
| CEP55 | centrosomal protein 55kDa | -0.00864682 |
| COL3A1 | collagen, type III, alpha 1 | -0.00864368 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00862488 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00861954 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00847708 |
| MEIS2 | Meis homeobox 2 | -0.00845394 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00838422 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00834986 |
| AQP9 | aquaporin 9 | -0.00829726 |
| QKI | QKI, KH domain containing, RNA binding | -0.00826747 |
| MECOM | MDS1 and EVI1 complex locus | -0.00826014 |
| COL5A2 | collagen, type V, alpha 2 | -0.00813762 |
| LMNB1 | lamin B1 | -0.00813754 |
| DCN | decorin | -0.00803996 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00800091 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00793724 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.00793176 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0079169 |
| CALD1 | caldesmon 1 | -0.00791401 |
| PCLAF | PCNA clamp associated factor | -0.00790629 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00788267 |
| CAVIN1 | caveolae associated protein 1 | -0.00787134 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00784708 |
| HOPX | HOP homeobox | -0.00784565 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00783995 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00781337 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00773974 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00772851 |
| DUT | deoxyuridine triphosphatase | -0.00769669 |
| G0S2 | G0/G1 switch 2 | -0.00768516 |
| NDC80 | NDC80 kinetochore complex component | -0.0076692 |
| RXRA | retinoid X receptor, alpha | -0.0076281 |
| CD14 | CD14 molecule | -0.00761254 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00759853 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.0075969 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0075758 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00757451 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00755777 |
| DMXL2 | Dmx-like 2 | -0.00754804 |
| NID1 | nidogen 1 | -0.00753036 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0075228 |
| CES1 | carboxylesterase 1 | -0.0075089 |
| LUM | lumican | -0.00747838 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00740205 |
| POSTN | periostin, osteoblast specific factor | -0.0073877 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00738714 |
| FNBP1 | formin binding protein 1 | -0.00734407 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00733327 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00733233 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00732765 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00729463 |
| TAGLN | transgelin | -0.00727077 |
| ZW10 | zw10 kinetochore protein | -0.00725536 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00724048 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00723383 |
| SRGN | serglycin | -0.00722497 |
| CAV2 | caveolin 2 | -0.00718985 |
| ATMIN | ATM interactor | -0.00718466 |
| MRTFB | myocardin related transcription factor B | -0.00718269 |
| PDGFC | platelet derived growth factor C | -0.0071433 |
| SETBP1 | SET binding protein 1 | -0.00713752 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00712614 |
| NUDCD3 | NudC domain containing 3 | -0.0071192 |
| PLTP | phospholipid transfer protein | -0.00704204 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00702627 |
| CD320 | CD320 molecule | -0.00701083 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00700882 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00700786 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00700678 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0069999 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00699548 |
| DPT | dermatopontin | -0.00695193 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00692208 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00688264 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00687862 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00686752 |
| SNX10 | sorting nexin 10 | -0.00686465 |
| CBX1 | chromobox homolog 1 | -0.00685829 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00685364 |
| FANCI | Fanconi anemia, complementation group I | -0.00683649 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00679296 |
| KIF11 | kinesin family member 11 | -0.00674475 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00674026 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00673755 |
| FOXM1 | forkhead box M1 | -0.00673286 |
| RRM2 | ribonucleotide reductase M2 | -0.0067261 |
| CCNB1 | cyclin B1 | -0.00671484 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00671113 |
| BRCA1 | breast cancer 1, early onset | -0.00670683 |
| CCND2 | cyclin D2 | -0.00670368 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00669366 |
| DCLK1 | doublecortin-like kinase 1 | -0.00668485 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00667251 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00666349 |
| IL33 | interleukin 33 | -0.00666232 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00665614 |
| SNX1 | sorting nexin 1 | -0.00664484 |
| C7 | complement component 7 | -0.00662068 |
| CDK14 | cyclin-dependent kinase 14 | -0.00660078 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00658248 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00658141 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00657956 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.0065752 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00656866 |
| ITM2A | integral membrane protein 2A | -0.00655457 |
| ASPN | asporin | -0.00654389 |
| DIXDC1 | DIX domain containing 1 | -0.0065414 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00653326 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00653041 |
| CNN3 | calponin 3, acidic | -0.006474 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00647389 |
| HMGB2 | high mobility group box 2 | -0.00645773 |
| KRT23 | keratin 23, type I | -0.00644351 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0064311 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0064304 |
| AOC3 | amine oxidase, copper containing 3 | -0.00641655 |
| MFAP5 | microfibrillar associated protein 5 | -0.00641317 |
| C1R | complement component 1, r subcomponent | -0.0064046 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00639534 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00638643 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00637725 |
| S100A9 | S100 calcium binding protein A9 | -0.00636917 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00636056 |
| RDX | radixin | -0.00635154 |
| INSIG1 | insulin induced gene 1 | -0.00634365 |
| NOTCH2 | notch 2 | -0.00633945 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00633616 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00632212 |
| FAM3C | family with sequence similarity 3, member C | -0.00631623 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00630848 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00630617 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00629186 |
| CEL | carboxyl ester lipase | -0.00628484 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00627911 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00625165 |
| CFB | complement factor B | -0.00623324 |
| MANSC1 | MANSC domain containing 1 | -0.00622088 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00621091 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00621022 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00620588 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00620418 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00619929 |
| PLN | phospholamban | -0.00618307 |
| EPHA3 | EPH receptor A3 | -0.00618129 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00617545 |
| NTS | neurotensin | -0.00617077 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00617019 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00615662 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.00615574 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00614268 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00613187 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00612531 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00611929 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00611294 |
| LAMA4 | laminin, alpha 4 | -0.00610115 |
| F8 | coagulation factor VIII, procoagulant component | -0.00609479 |
| OGN | osteoglycin | -0.00607744 |
| PALMD | palmdelphin | -0.00607265 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00606571 |
| MEST | mesoderm specific transcript | -0.00606448 |
| CFI | complement factor I | -0.00604117 |
| MAML1 | mastermind-like 1 (Drosophila) | -0.00603855 |
| ZNF532 | zinc finger protein 532 | -0.0060127 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00600643 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00599386 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00598654 |
| APMAP | adipocyte plasma membrane associated protein | -0.00598422 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00597951 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00597929 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00597619 |
| FBN1 | fibrillin 1 | -0.00595837 |
| PER3 | period circadian clock 3 | -0.00595007 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | -0.00594926 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00592586 |
| TIMELESS | timeless circadian clock | -0.00592302 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.005921 |
| CTSK | cathepsin K | -0.0059144 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00591357 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00590575 |
| CFH | complement factor H | -0.00590258 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00589957 |
| COL5A1 | collagen, type V, alpha 1 | -0.00589872 |
| SEC24D | SEC24 family member D | -0.00588042 |
| S100A2 | S100 calcium binding protein A2 | -0.00586863 |
| PLS3 | plastin 3 | -0.00586273 |
| S100A12 | S100 calcium binding protein A12 | -0.00586151 |
| TK1 | thymidine kinase 1, soluble | -0.00585423 |
| CCNA2 | cyclin A2 | -0.00585269 |
| MECP2 | methyl CpG binding protein 2 | -0.00584986 |
| SORD | sorbitol dehydrogenase | -0.00584908 |
| RIN2 | Ras and Rab interactor 2 | -0.00581833 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00581456 |
