TCF7 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transcription factor 7 (T-cell specific, HMG-box)|The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 6932)
External Link https://ncbi.nlm.nih.gov/gene/6932
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Genes

499 genes differentially expressed following the TCF7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0164078
AKAP12 A kinase (PRKA) anchor protein 12 0.0150856
ANXA1 annexin A1 0.0147822
CHEK2 checkpoint kinase 2 0.0143357
TFPI2 tissue factor pathway inhibitor 2 0.0141314
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.0139437
CA2 carbonic anhydrase II 0.0136466
IFI27 interferon, alpha-inducible protein 27 0.0128579
CRYAB crystallin, alpha B 0.0128221
MT1X metallothionein 1X 0.0127195
SFRP1 secreted frizzled-related protein 1 0.0125144
MT1G metallothionein 1G 0.0122697
PTHLH parathyroid hormone-like hormone 0.0119214
IFI16 interferon, gamma-inducible protein 16 0.011465
CXCL12 chemokine (C-X-C motif) ligand 12 0.0113841
AQP1 aquaporin 1 (Colton blood group) 0.011299
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0110848
ATF3 activating transcription factor 3 0.0110836
MT1H metallothionein 1H 0.010976
MT1F metallothionein 1F 0.0109266
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0109034
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0108944
NT5E 5'-nucleotidase, ecto (CD73) 0.0108385
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0106684
MT1HL1 metallothionein 1H-like 1 0.0106067
BHLHE41 basic helix-loop-helix family, member e41 0.0106043
MME membrane metallo-endopeptidase 0.0105985
FMO1 flavin containing monooxygenase 1 0.0105624
GBP1 guanylate binding protein 1, interferon-inducible 0.0104561
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.0104315
THBS2 thrombospondin 2 0.0103856
DEFB1 defensin, beta 1 0.01022
GRB7 growth factor receptor-bound protein 7 0.0101816
NLRP2 NLR family, pyrin domain containing 2 0.0101363
MT1E metallothionein 1E 0.00984522
ADD3 adducin 3 (gamma) 0.00968329
SGK1 serum/glucocorticoid regulated kinase 1 0.00966425
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00966368
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00954845
NIBAN1 niban apoptosis regulator 1 0.00951268
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00949914
ANPEP alanyl (membrane) aminopeptidase 0.00947567
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00942188
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00941592
SRPX sushi-repeat containing protein, X-linked 0.0093675
SYNGR3 synaptogyrin 3 0.00931857
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00931833
SCPEP1 serine carboxypeptidase 1 0.00927905
MX1 MX dynamin-like GTPase 1 0.00926732
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00919304
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00914747
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00914654
SIRPA signal-regulatory protein alpha 0.00908574
PRAME preferentially expressed antigen in melanoma 0.00891277
RND3 Rho family GTPase 3 0.00891229
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00888249
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00882006
FXYD3 FXYD domain containing ion transport regulator 3 0.00879835
ZYX zyxin 0.00876414
ZFP36L2 ZFP36 ring finger protein-like 2 0.0087222
PDE4B phosphodiesterase 4B, cAMP-specific 0.00865284
ACKR3 atypical chemokine receptor 3 0.00863009
FRMD4B FERM domain containing 4B 0.00860376
CFI complement factor I 0.00857796
HIST1H2AC histone cluster 1, H2ac 0.00855585
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00852161
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00850926
BICC1 BicC family RNA binding protein 1 0.00850289
KRT14 keratin 14, type I 0.00846891
EMX2 empty spiracles homeobox 2 0.00843998
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0084222
DMD dystrophin 0.00840275
LPAR6 lysophosphatidic acid receptor 6 0.00836827
AK4 adenylate kinase 4 0.00834043
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0082822
OPTN optineurin 0.00825951
HBB hemoglobin, beta 0.00823935
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00820459
TICAM1 toll-like receptor adaptor molecule 1 0.00820397
NID1 nidogen 1 0.00820029
KRT7 keratin 7, type II 0.00819814
CD93 CD93 molecule 0.00815191
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00814928
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00811085
BAG3 BCL2-associated athanogene 3 0.00807458
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00803328
KLK10 kallikrein-related peptidase 10 0.00800213
TAC1 tachykinin, precursor 1 0.00796053
ZEB2 zinc finger E-box binding homeobox 2 0.00795108
EGR2 early growth response 2 0.00794809
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00791959
FOSL2 FOS-like antigen 2 0.00790877
TPD52L1 tumor protein D52-like 1 0.00789198
MAL mal, T-cell differentiation protein 0.00788319
GPR137B G protein-coupled receptor 137B 0.00783397
NRCAM neuronal cell adhesion molecule 0.00781446
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00779064
MT2A metallothionein 2A 0.00778775
HTRA1 HtrA serine peptidase 1 0.00774806
DAXX death-domain associated protein 0.00773691
EIF5A eukaryotic translation initiation factor 5A 0.0077178
BCL3 B-cell CLL/lymphoma 3 0.00771252
LXN latexin 0.00770568
CSRP1 cysteine and glycine-rich protein 1 0.0077028
LAMA4 laminin, alpha 4 0.00767046
PELI1 pellino E3 ubiquitin protein ligase 1 0.00765903
CD86 CD86 molecule 0.00765896
ZBED2 zinc finger, BED-type containing 2 0.00765829
COG7 component of oligomeric golgi complex 7 0.0076399
VCL vinculin 0.00761431
PXDN peroxidasin 0.00761059
MFAP5 microfibrillar associated protein 5 0.0075965
CTNND1 catenin (cadherin-associated protein), delta 1 0.00757845
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00757166
STOM stomatin 0.0075597
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.00751773
PROM1 prominin 1 0.00749752
KCTD12 potassium channel tetramerization domain containing 12 0.0074866
CAV2 caveolin 2 0.00746677
MYOF myoferlin 0.00746584
MGST3 microsomal glutathione S-transferase 3 0.0074307
TRIM22 tripartite motif containing 22 0.00738457
AOC1 amine oxidase, copper containing 1 0.007384
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.00736747
TLE4 transducin-like enhancer of split 4 0.00732255
DEPTOR DEP domain containing MTOR-interacting protein 0.00731478
HSPH1 heat shock 105kDa/110kDa protein 1 0.00730823
C1ORF54 chromosome 1 open reading frame 54 0.00730563
CXCL10 chemokine (C-X-C motif) ligand 10 0.00729388
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00724829
DPP4 dipeptidyl-peptidase 4 0.00724333
PNMA2 paraneoplastic Ma antigen 2 0.00723384
PNMA8A PNMA family member 8A 0.00723165
BAMBI BMP and activin membrane-bound inhibitor 0.0071834
EGR3 early growth response 3 0.00717765
KLF11 Kruppel-like factor 11 0.00717374
RAB29 RAB29, member RAS oncogene family 0.00714347
PLAUR plasminogen activator, urokinase receptor 0.00704259
PITX3 paired-like homeodomain 3 0.00701857
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00701178
TPBG trophoblast glycoprotein 0.00699926
PLK2 polo-like kinase 2 0.00698005
MEIS2 Meis homeobox 2 0.0069506
ETHE1 ethylmalonic encephalopathy 1 0.00694327
HSPA2 heat shock 70kDa protein 2 0.00692427
PDE8B phosphodiesterase 8B 0.00689954
OAT ornithine aminotransferase 0.00687486
FABP4 fatty acid binding protein 4, adipocyte 0.00686596
COL15A1 collagen, type XV, alpha 1 0.00685416
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00685039
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00683979
KRT23 keratin 23, type I 0.00683428
GAS1 growth arrest-specific 1 0.00683017
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.0068237
FSCN1 fascin actin-bundling protein 1 0.00682151
PSAP prosaposin 0.00678387
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00677919
AREG amphiregulin 0.00677087
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00676487
CLIC4 chloride intracellular channel 4 0.00675364
MCL1 myeloid cell leukemia 1 0.00675218
ISG20 interferon stimulated exonuclease gene 20kDa 0.00673763
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.00672936
PDZK1IP1 PDZK1 interacting protein 1 0.00670774
HIST1H2BD histone cluster 1, H2bd 0.00670224
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00669401
DENND3 DENN/MADD domain containing 3 0.00668032
CLDN10 claudin 10 0.00667567
CALB1 calbindin 1, 28kDa 0.00667525
BEX4 brain expressed, X-linked 4 0.00666875
TMEM47 transmembrane protein 47 0.00666315
PLAU plasminogen activator, urokinase 0.00661963
PADI2 peptidyl arginine deiminase, type II 0.0066159
VCAM1 vascular cell adhesion molecule 1 0.00660225
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00660202
WLS wntless Wnt ligand secretion mediator 0.00659635
PDZD2 PDZ domain containing 2 0.00658597
ARMCX1 armadillo repeat containing, X-linked 1 0.00656227
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.0065466
HOXB7 homeobox B7 0.00651166
NOX4 NADPH oxidase 4 0.00650359
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00649541
SRGN serglycin 0.00649518
RSAD2 radical S-adenosyl methionine domain containing 2 0.00649108
KRT15 keratin 15, type I 0.00648927
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00648361
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00648337
WWTR1 WW domain containing transcription regulator 1 0.00647978
PLBD1 phospholipase B domain containing 1 0.00647602
SELE selectin E 0.00644154
TPK1 thiamin pyrophosphokinase 1 0.00643979
VCAN versican 0.0064364
TRIM38 tripartite motif containing 38 0.00643239
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00641683
FRY furry homolog (Drosophila) 0.00640024
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00639878
ADGRL2 adhesion G protein-coupled receptor L2 0.00638439
MMD monocyte to macrophage differentiation-associated 0.00637509
TOX thymocyte selection-associated high mobility group box 0.00635015
PLAGL1 pleiomorphic adenoma gene-like 1 0.00632651
ALCAM activated leukocyte cell adhesion molecule 0.00631934
PLSCR4 phospholipid scramblase 4 0.00631445
NDFIP1 Nedd4 family interacting protein 1 0.00630375
RGCC regulator of cell cycle 0.00630338
GRAMD2B GRAM domain containing 2B 0.00630011
SAMD9 sterile alpha motif domain containing 9 0.00629544
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00629276
AGTR1 angiotensin II receptor, type 1 0.00628015
SGCE sarcoglycan, epsilon 0.0062753
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00627271
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00626812
LY96 lymphocyte antigen 96 0.00626604
MN1 meningioma (disrupted in balanced translocation) 1 0.00623985
TUFT1 tuftelin 1 0.00621873
SYNPO synaptopodin 0.00621167
RCAN2 regulator of calcineurin 2 0.0062035
NEFH neurofilament, heavy polypeptide 0.00617442
BIK BCL2-interacting killer (apoptosis-inducing) 0.00615141
SLC16A4 solute carrier family 16, member 4 0.00614905
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00613758
FOLR1 folate receptor 1 (adult) 0.0061176
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00610211
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00609766
C10ORF10 chromosome 10 open reading frame 10 0.00609668
GPI glucose-6-phosphate isomerase 0.00609589
PUF60 poly-U binding splicing factor 60KDa 0.00608043
MYRF myelin regulatory factor 0.00607755
RCAN1 regulator of calcineurin 1 0.00607286
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00607032
CLDN7 claudin 7 0.00605302
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.006046
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00604519
GBP2 guanylate binding protein 2, interferon-inducible 0.00603868
TMEM140 transmembrane protein 140 0.00600838
GAB2 GRB2-associated binding protein 2 0.00600479
MVP major vault protein 0.00599802
CSRP2 cysteine and glycine-rich protein 2 0.00598547
NEU1 sialidase 1 (lysosomal sialidase) 0.00597786
QKI QKI, KH domain containing, RNA binding 0.00597099
CAST calpastatin 0.00596557
CXCL11 chemokine (C-X-C motif) ligand 11 0.00596555
GALC galactosylceramidase 0.00596008
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00596006
ADAM10 ADAM metallopeptidase domain 10 0.00595988
EDN1 endothelin 1 0.00595655
SELENBP1 selenium binding protein 1 0.00595527
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00592914
H1-2 H1.2 linker histone, cluster member 0.00592722
GMPR guanosine monophosphate reductase 0.00591909
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00591622

decreased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0270907
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.0116839
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0112042
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0107767
SDC2 syndecan 2 -0.0106663
OLFM1 olfactomedin 1 -0.0102965
TPSAB1 tryptase alpha/beta 1 -0.00992501
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00978719
NVL nuclear VCP-like -0.00960846
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00956501
EXPH5 exophilin 5 -0.00938706
CCL19 chemokine (C-C motif) ligand 19 -0.00937948
FOXF1 forkhead box F1 -0.00916111
DSP desmoplakin -0.00887814
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00855232
S100A2 S100 calcium binding protein A2 -0.00839329
NUSAP1 nucleolar and spindle associated protein 1 -0.00828128
SLC16A6 solute carrier family 16, member 6 -0.00822186
DBF4 DBF4 zinc finger -0.00808889
SFTPB surfactant protein B -0.00803251
EMP2 epithelial membrane protein 2 -0.00790171
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00780753
MAP7 microtubule-associated protein 7 -0.00767135
APOA2 apolipoprotein A-II -0.00759145
LEF1 lymphoid enhancer-binding factor 1 -0.00751959
CHN2 chimerin 2 -0.00742799
PPA2 pyrophosphatase (inorganic) 2 -0.00733206
PDLIM3 PDZ and LIM domain 3 -0.00724552
NELL2 NEL-like 2 (chicken) -0.00724134
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00719477
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00718964
REEP1 receptor accessory protein 1 -0.00717311
BRD2 bromodomain containing 2 -0.00714262
KDM5D lysine (K)-specific demethylase 5D -0.00707153
GNAS GNAS complex locus -0.0069508
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00692868
MTARC1 mitochondrial amidoxime reducing component 1 -0.00687078
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00683907
IGFBP1 insulin-like growth factor binding protein 1 -0.00682867
UBL3 ubiquitin-like 3 -0.00681979
CCL21 chemokine (C-C motif) ligand 21 -0.00680434
CNPY3 canopy FGF signaling regulator 3 -0.00679699
HMGB3 high mobility group box 3 -0.00669964
SFTPA2 surfactant protein A2 -0.00667743
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00659508
DEK DEK proto-oncogene -0.00656644
RAPSN receptor-associated protein of the synapse -0.0064939
GSTT1 glutathione S-transferase theta 1 -0.00648567
HMGB1 high mobility group box 1 -0.00645218
NPM3 nucleophosmin/nucleoplasmin 3 -0.00645
MMP9 matrix metallopeptidase 9 -0.00637076
TARDBP TAR DNA binding protein -0.00636789
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00634037
CUL3 cullin 3 -0.00632896
TXNIP thioredoxin interacting protein -0.00631772
COL2A1 collagen, type II, alpha 1 -0.00629954
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00628082
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.00623955
PRKCB protein kinase C, beta -0.0061864
HP haptoglobin -0.00610807
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00609895
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00604513
HMGB2 high mobility group box 2 -0.00602481
CCL20 chemokine (C-C motif) ligand 20 -0.00601617
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.0060115
BCLAF1 BCL2-associated transcription factor 1 -0.00597353
MBD1 methyl-CpG binding domain protein 1 -0.00595466
ING3 inhibitor of growth family, member 3 -0.00594613
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0059417
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00592909
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -0.00591423
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00591158
CRLF1 cytokine receptor-like factor 1 -0.00590185
KRT10 keratin 10, type I -0.00589004
KIF5B kinesin family member 5B -0.00588682
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.00586179
GNPAT glyceronephosphate O-acyltransferase -0.00583295
AKR1C2 aldo-keto reductase family 1, member C2 -0.00582482
SRSF7 serine/arginine-rich splicing factor 7 -0.00580373
ZBTB38 zinc finger and BTB domain containing 38 -0.005784
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00577671
STK26 serine/threonine protein kinase 26 -0.0057333
FAM53B family with sequence similarity 53, member B -0.00572392
CD2 CD2 molecule -0.0057084
AKR1C1 aldo-keto reductase family 1, member C1 -0.00569832
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00568293
GAL galanin/GMAP prepropeptide -0.00567825
FOXA2 forkhead box A2 -0.00567059
PRKCZ protein kinase C, zeta -0.00567023
STAG2 stromal antigen 2 -0.00566847
AP5M1 adaptor-related protein complex 5, mu 1 subunit -0.00566235
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.00565701
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00565302
SFN stratifin -0.0056383
PCP4 Purkinje cell protein 4 -0.00563363
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00560444
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00559764
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00559399
IL7R interleukin 7 receptor -0.00558432
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.00557294
AMDHD2 amidohydrolase domain containing 2 -0.00556515
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00556497
ESRP2 epithelial splicing regulatory protein 2 -0.00553045
RWDD1 RWD domain containing 1 -0.00552142
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00551346
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00544617
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00543753
BPIFA1 BPI fold containing family A, member 1 -0.00542882
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0054124
CD8A CD8a molecule -0.00540857
KLHL23 kelch-like family member 23 -0.00540246
VDAC3 voltage-dependent anion channel 3 -0.00540038
CD320 CD320 molecule -0.00539999
CD99 CD99 molecule -0.00537878
NSL1 NSL1, MIS12 kinetochore complex component -0.00537456
HOPX HOP homeobox -0.00532394
PBRM1 polybromo 1 -0.00532277
EPHB2 EPH receptor B2 -0.00530327
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00530232
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -0.00529686
ANGEL2 angel homolog 2 (Drosophila) -0.00528435
RXRA retinoid X receptor, alpha -0.00528076
SMYD2 SET and MYND domain containing 2 -0.00527101
EI24 etoposide induced 2.4 -0.00527053
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -0.00526854
SFPQ splicing factor proline/glutamine-rich -0.00526753
COPS4 COP9 signalosome subunit 4 -0.00524874
CRY1 cryptochrome circadian clock 1 -0.00524595
SORD sorbitol dehydrogenase -0.00523941
RAP2A RAP2A, member of RAS oncogene family -0.00523206
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00523006
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00522326
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00521804
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00520989
CRMP1 collapsin response mediator protein 1 -0.00520101
H2AZ1 H2A.Z variant histone 1 -0.00518261
ELN elastin -0.00517354
RPA3 replication protein A3, 14kDa -0.00517232
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00517102
SEPTIN7 septin 7 -0.005163
SRP9 signal recognition particle 9kDa -0.00515573
FUS FUS RNA binding protein -0.00513228
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00511283
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00511035
C4BPB complement component 4 binding protein, beta -0.00510675
FASN fatty acid synthase -0.00510091
GSE1 Gse1 coiled-coil protein -0.0050776
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00507538
LIN7C lin-7 homolog C (C. elegans) -0.00507265
UFL1 UFM1-specific ligase 1 -0.00506433
SIRT3 sirtuin 3 -0.00506243
MPC1 mitochondrial pyruvate carrier 1 -0.00504906
SLC35E2B solute carrier family 35, member E2B -0.00502807
HES1 hes family bHLH transcription factor 1 -0.00502648
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00502479
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00502349
SLC38A1 solute carrier family 38, member 1 -0.00501633
TRMT5 tRNA methyltransferase 5 -0.00501556
CLCA1 chloride channel accessory 1 -0.0050086
ENOPH1 enolase-phosphatase 1 -0.00500746
MLPH melanophilin -0.00500429
REPIN1 replication initiator 1 -0.0050003
USP48 ubiquitin specific peptidase 48 -0.00499437
TFAM transcription factor A, mitochondrial -0.00497741
NELFCD negative elongation factor complex member C/D -0.00496739
FAM46C family with sequence similarity 46, member C -0.00496277
MMP12 matrix metallopeptidase 12 -0.00495439
ASF1A anti-silencing function 1A histone chaperone -0.00494245
DMBT1 deleted in malignant brain tumors 1 -0.00493692
RAB25 RAB25, member RAS oncogene family -0.00493685
HNRNPR heterogeneous nuclear ribonucleoprotein R -0.00493233
ADAMDEC1 ADAM-like, decysin 1 -0.00492053
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.0048997
C1ORF174 chromosome 1 open reading frame 174 -0.0048968
SRSF3 serine/arginine-rich splicing factor 3 -0.00489507
CD6 CD6 molecule -0.00489428
MXRA8 matrix-remodelling associated 8 -0.00487646
TRAPPC2L trafficking protein particle complex 2-like -0.004876
PLEC plectin -0.00487486
PRRC2A proline-rich coiled-coil 2A -0.00487306
GSTO1 glutathione S-transferase omega 1 -0.00487278
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00486233
THAP12 THAP domain containing 12 -0.00485752
EMP3 epithelial membrane protein 3 -0.00485728
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00485639
MORF4L1 mortality factor 4 like 1 -0.00483191
ARL4A ADP-ribosylation factor-like 4A -0.00482941
EML3 echinoderm microtubule associated protein like 3 -0.00482867
ABHD2 abhydrolase domain containing 2 -0.00482649
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.004825
CHPT1 choline phosphotransferase 1 -0.00482096
SIKE1 suppressor of IKBKE 1 -0.0048003
FBXO28 F-box protein 28 -0.00478888
BZW1 basic leucine zipper and W2 domains 1 -0.00478883
IGFBP5 insulin-like growth factor binding protein 5 -0.0047819
APOB apolipoprotein B -0.00477642
SFTPC surfactant protein C -0.004774
SRSF6 serine/arginine-rich splicing factor 6 -0.00477383
TUBB4B tubulin, beta 4B class IVb -0.00477305
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00477077
CDC42SE1 CDC42 small effector 1 -0.00476631
PHACTR2 phosphatase and actin regulator 2 -0.00476287
NUP107 nucleoporin 107kDa -0.0047362
NBPF10 neuroblastoma breakpoint family, member 10 -0.00472463
CPVL carboxypeptidase, vitellogenic-like -0.00471816
HDAC1 histone deacetylase 1 -0.00471595
SETD6 SET domain containing 6 -0.00470353
MEIS1 Meis homeobox 1 -0.00470021
MATN2 matrilin 2 -0.00469585
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00468943
ESR1 estrogen receptor 1 -0.004688
ITM2A integral membrane protein 2A -0.00468638
SPIN1 spindlin 1 -0.0046813
DES desmin -0.00467874
LOR loricrin -0.00467571
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0046673
PHF10 PHD finger protein 10 -0.00465729
BRD8 bromodomain containing 8 -0.00465383
SIM2 single-minded family bHLH transcription factor 2 -0.00464934
TMEM106C transmembrane protein 106C -0.00464771
DDHD2 DDHD domain containing 2 -0.00464065
PTCH1 patched 1 -0.00462612
NOTCH2NL notch 2 N-terminal like -0.0046179
FCMR Fc fragment of IgM receptor -0.00461025
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00460413
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -0.00459064
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.00458506
FAM120A family with sequence similarity 120A -0.00458463
FOXA1 forkhead box A1 -0.00457161
TRA2B transformer 2 beta homolog (Drosophila) -0.00456749
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.00455836
THYN1 thymocyte nuclear protein 1 -0.00455723
BUB3 BUB3 mitotic checkpoint protein -0.00454081
CD209 CD209 molecule -0.00453965
IRS1 insulin receptor substrate 1 -0.00452938
KMT5B lysine methyltransferase 5B -0.00452587
CTSH cathepsin H -0.00452357
CCDC92 coiled-coil domain containing 92 -0.00452346
HSPA14 heat shock 70kDa protein 14 -0.00451617
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0045153
PRDX2 peroxiredoxin 2 -0.00450778
HMGN2 high mobility group nucleosomal binding domain 2 -0.00450739
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00450174
CKAP2 cytoskeleton associated protein 2 -0.00449982
CHKB choline kinase beta -0.00447994
CXADR coxsackie virus and adenovirus receptor -0.00447774
GRWD1 glutamate-rich WD repeat containing 1 -0.00447476
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00447393
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00446699