TCF7L2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transcription factor 7-like 2 (T-cell specific, HMG-box)|This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 6934)
External Link https://ncbi.nlm.nih.gov/gene/6934
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Genes

500 genes differentially expressed following the TCF7L2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa 0.0104661
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00933504
GNAS GNAS complex locus 0.00919726
WT1 Wilms tumor 1 0.00814476
PMP22 peripheral myelin protein 22 0.00752423
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00726035
MARCKSL1 MARCKS-like 1 0.00725728
GMPR guanosine monophosphate reductase 0.00703809
PLAT plasminogen activator, tissue 0.00687402
KRT7 keratin 7, type II 0.00686048
PLAAT3 phospholipase A and acyltransferase 3 0.00671022
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00657028
CENPU centromere protein U 0.00650271
BASP1 brain abundant, membrane attached signal protein 1 0.00639786
GOLGA8A golgin A8 family, member A 0.00639116
LCN2 lipocalin 2 0.00633318
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00629021
LAPTM4B lysosomal protein transmembrane 4 beta 0.0062508
CDC45 cell division cycle 45 0.00619124
IRS2 insulin receptor substrate 2 0.00616287
PLTP phospholipid transfer protein 0.0061604
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00608433
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00599625
LUM lumican 0.00591675
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00577117
RHOBTB3 Rho-related BTB domain containing 3 0.00576891
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00576026
MXRA7 matrix-remodelling associated 7 0.00573064
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00569036
CD320 CD320 molecule 0.0056828
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00563663
DHCR24 24-dehydrocholesterol reductase 0.00561644
PRAME preferentially expressed antigen in melanoma 0.00559465
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00556083
C3ORF14 chromosome 3 open reading frame 14 0.00554979
TRIB2 tribbles pseudokinase 2 0.00553834
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00551564
MLPH melanophilin 0.00546067
FASN fatty acid synthase 0.00544155
CCP110 centriolar coiled coil protein 110kDa 0.00537386
H2AX H2A.X variant histone 0.00536011
SRGN serglycin 0.00532515
APOD apolipoprotein D 0.00531977
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00528893
TBC1D4 TBC1 domain family, member 4 0.00527217
KAT2B K(lysine) acetyltransferase 2B 0.00522668
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.0052238
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00522338
CLGN calmegin 0.00522206
CDC20 cell division cycle 20 0.00520748
NNMT nicotinamide N-methyltransferase 0.0052039
KAZN kazrin, periplakin interacting protein 0.00519621
ITK IL2-inducible T-cell kinase 0.00518324
GOLM1 golgi membrane protein 1 0.00514773
HOXB2 homeobox B2 0.00513553
TES testin LIM domain protein 0.00509671
OLFM4 olfactomedin 4 0.00501308
MEIS2 Meis homeobox 2 0.00494974
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00491348
CD38 CD38 molecule 0.00488744
TLE4 transducin-like enhancer of split 4 0.00486751
NID2 nidogen 2 (osteonidogen) 0.00479837
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00478914
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0047862
CD81 CD81 molecule 0.00478461
PRKCA protein kinase C, alpha 0.00478069
C1QB complement component 1, q subcomponent, B chain 0.00475247
TRAF5 TNF receptor-associated factor 5 0.00475092
RPIA ribose 5-phosphate isomerase A 0.00474497
ACP5 acid phosphatase 5, tartrate resistant 0.00469499
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00468251
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00467662
SPON1 spondin 1, extracellular matrix protein 0.00466498
IL13RA2 interleukin 13 receptor, alpha 2 0.00466438
TPBG trophoblast glycoprotein 0.00464734
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00464018
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.0046257
RRAGD Ras-related GTP binding D 0.00461445
MUC16 mucin 16, cell surface associated 0.00461269
CD44 CD44 molecule (Indian blood group) 0.004601
YARS1 tyrosyl-tRNA synthetase 1 0.0045942
GPX2 glutathione peroxidase 2 0.00458967
ZFPM2 zinc finger protein, FOG family member 2 0.00458358
HYOU1 hypoxia up-regulated 1 0.00457949
IGFBP4 insulin-like growth factor binding protein 4 0.00456362
LXN latexin 0.00455205
NTS neurotensin 0.00454407
SNX11 sorting nexin 11 0.00454178
GREM1 gremlin 1, DAN family BMP antagonist 0.00454085
TGM2 transglutaminase 2 0.00453799
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00453362
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.0045256
LPAR1 lysophosphatidic acid receptor 1 0.00452182
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00446795
ACAT2 acetyl-CoA acetyltransferase 2 0.00445924
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00445637
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00445508
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00445233
GPNMB glycoprotein (transmembrane) nmb 0.00444579
ELP1 elongator acetyltransferase complex subunit 1 0.0044157
TWIST1 twist family bHLH transcription factor 1 0.00440594
DNM1 dynamin 1 0.00438984
TBC1D31 TBC1 domain family, member 31 0.00438872
BAMBI BMP and activin membrane-bound inhibitor 0.00438436
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00436803
NRIP1 nuclear receptor interacting protein 1 0.00436378
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00433601
JMJD6 jumonji domain containing 6 0.00432885
LEF1 lymphoid enhancer-binding factor 1 0.00432784
PLXNC1 plexin C1 0.00430476
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.00427127
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00426274
C1QA complement component 1, q subcomponent, A chain 0.00426186
CSK c-src tyrosine kinase 0.00425674
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00424658
PPARG peroxisome proliferator-activated receptor gamma 0.00422948
ASPH aspartate beta-hydroxylase 0.0042025
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.00420064
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00419945
RSAD1 radical S-adenosyl methionine domain containing 1 0.00418744
PRPF4 pre-mRNA processing factor 4 0.0041834
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.00418334
SCRIB scribbled planar cell polarity protein 0.00417131
MDK midkine (neurite growth-promoting factor 2) 0.00416317
MT1X metallothionein 1X 0.00414533
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00411839
GBP1 guanylate binding protein 1, interferon-inducible 0.00410689
S100B S100 calcium binding protein B 0.00410466
C3 complement component 3 0.00409346
TNC tenascin C 0.00409123
TIMELESS timeless circadian clock 0.00408931
TIMP1 TIMP metallopeptidase inhibitor 1 0.00408736
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00408665
TMEM165 transmembrane protein 165 0.00407467
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.00406956
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00406489
PTDSS1 phosphatidylserine synthase 1 0.00405633
TK1 thymidine kinase 1, soluble 0.00404195
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00402178
MICU2 mitochondrial calcium uptake 2 0.00401448
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.00399978
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00399857
GALC galactosylceramidase 0.00399774
BGN biglycan 0.00399086
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00398384
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 0.003975
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00395435
MOK MOK protein kinase 0.00393089
ELOVL5 ELOVL fatty acid elongase 5 0.00392878
COL1A1 collagen, type I, alpha 1 0.00392523
PLXND1 plexin D1 0.00391286
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00390805
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00390028
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.00389924
ECPAS Ecm29 proteasome adaptor and scaffold 0.00388756
CHN1 chimerin 1 0.00388581
HSDL2 hydroxysteroid dehydrogenase like 2 0.00388437
SLC46A3 solute carrier family 46, member 3 0.00387866
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.00387283
PLP1 proteolipid protein 1 0.00386934
TTC39A tetratricopeptide repeat domain 39A 0.00386803
CFB complement factor B 0.00385918
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.003842
KIAA0125 KIAA0125 0.00383519
LIMA1 LIM domain and actin binding 1 0.0038255
ZIC1 Zic family member 1 0.00381566
IL2RB interleukin 2 receptor, beta 0.00380974
AGTR1 angiotensin II receptor, type 1 0.00380869
TDO2 tryptophan 2,3-dioxygenase 0.00380591
FXYD5 FXYD domain containing ion transport regulator 5 0.00380446
CCL8 chemokine (C-C motif) ligand 8 0.00379622
DLK1 delta-like 1 homolog (Drosophila) 0.00379572
MELK maternal embryonic leucine zipper kinase 0.00378424
MED22 mediator complex subunit 22 0.00377638
MMP1 matrix metallopeptidase 1 0.00377558
LRRC6 leucine rich repeat containing 6 0.00377355
GGCT gamma-glutamylcyclotransferase 0.00377284
BHLHE41 basic helix-loop-helix family, member e41 0.00376595
CD209 CD209 molecule 0.00376383
CEP170 centrosomal protein 170kDa 0.00376075
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.00374794
SLAMF1 signaling lymphocytic activation molecule family member 1 0.00374225
DUOX2 dual oxidase 2 0.00373922
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 0.00372511
GRAMD2B GRAM domain containing 2B 0.00372479
GOLGA8H golgin A8 family, member H 0.00372297
CRIP2 cysteine-rich protein 2 0.00370687
CCL19 chemokine (C-C motif) ligand 19 0.00370064
PASK PAS domain containing serine/threonine kinase 0.0036994
GUSB glucuronidase, beta 0.00369122
CFH complement factor H 0.00368643
SMC1A structural maintenance of chromosomes 1A 0.00367815
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00367083
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.00366257
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00365641
ADRM1 adhesion regulating molecule 1 0.00365597
QPRT quinolinate phosphoribosyltransferase 0.00365137
TPD52 tumor protein D52 0.00363508
AURKB aurora kinase B 0.00363454
CXCL6 chemokine (C-X-C motif) ligand 6 0.00363126
DEPTOR DEP domain containing MTOR-interacting protein 0.00363025
APOL1 apolipoprotein L, 1 0.00362977
WBP2 WW domain binding protein 2 0.00362811
PTGIS prostaglandin I2 (prostacyclin) synthase 0.0036232
LRRN3 leucine rich repeat neuronal 3 0.00361505
RNF144A ring finger protein 144A 0.00361077
CHD7 chromodomain helicase DNA binding protein 7 0.00360508
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00360135
MLEC malectin 0.0035972
MAGED1 melanoma antigen family D1 0.00359202
TMOD1 tropomodulin 1 0.00358621
HMGA1 high mobility group AT-hook 1 0.00357972
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00357392
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00357048
TNIK TRAF2 and NCK interacting kinase 0.00356707
ABLIM1 actin binding LIM protein 1 0.00356543
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.00356453
COL3A1 collagen, type III, alpha 1 0.00356072
RSAD2 radical S-adenosyl methionine domain containing 2 0.00354801
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0035463
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00354606
C2 complement component 2 0.00354513
WASF1 WAS protein family, member 1 0.00354162
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 0.00354017
IARS1 isoleucyl-tRNA synthetase 1 0.00353928
SNCAIP synuclein, alpha interacting protein 0.00353822
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00351497
SPART spartin 0.00351367
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00351316
LGALS13 lectin, galactoside-binding, soluble, 13 0.00350769
CXCL9 chemokine (C-X-C motif) ligand 9 0.00349832
CYRIB CYFIP related Rac1 interactor B 0.00349829
PTCH1 patched 1 0.00349621
GPR137B G protein-coupled receptor 137B 0.00349602
CTSB cathepsin B 0.00348838
KLHL21 kelch-like family member 21 0.00348516
DEFA5 defensin, alpha 5, Paneth cell-specific 0.0034822
TMC6 transmembrane channel-like 6 0.00346905
TSNAX translin-associated factor X 0.00346892
EML3 echinoderm microtubule associated protein like 3 0.00346288
RGS1 regulator of G-protein signaling 1 0.00345967
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00345807
DGKZ diacylglycerol kinase, zeta 0.00345712
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00345574
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00344301
FOXM1 forkhead box M1 0.00342894
SLC44A4 solute carrier family 44, member 4 0.00342867
CDK17 cyclin-dependent kinase 17 0.00342723
MT1F metallothionein 1F 0.00342586
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00341324

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0127774
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00875986
TNNT1 troponin T type 1 (skeletal, slow) -0.00752191
CLEC2B C-type lectin domain family 2, member B -0.00707766
BMP2 bone morphogenetic protein 2 -0.00689055
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00668243
PEG10 paternally expressed 10 -0.00651266
NCF2 neutrophil cytosolic factor 2 -0.00648082
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00640415
FHL1 four and a half LIM domains 1 -0.00637198
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00628828
RBM47 RNA binding motif protein 47 -0.00618841
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00612283
SLC38A1 solute carrier family 38, member 1 -0.00605638
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00601732
EFNA1 ephrin-A1 -0.0059209
NDRG1 N-myc downstream regulated 1 -0.00581311
RGCC regulator of cell cycle -0.00574216
CADM1 cell adhesion molecule 1 -0.00573793
SELENOW selenoprotein W -0.00565087
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00564908
FLNA filamin A, alpha -0.00562087
DEFB1 defensin, beta 1 -0.00560902
TNNC1 troponin C type 1 (slow) -0.00558058
DMD dystrophin -0.00556077
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00548624
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00545381
TXNIP thioredoxin interacting protein -0.00544587
APOA2 apolipoprotein A-II -0.00536439
ACOT9 acyl-CoA thioesterase 9 -0.0052996
STC2 stanniocalcin 2 -0.00522543
COBL cordon-bleu WH2 repeat protein -0.00518459
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00514549
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00513486
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00510355
S100A14 S100 calcium binding protein A14 -0.00509485
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00504552
CCN2 cellular communication network factor 2 -0.00504544
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00495656
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00488531
CRELD2 cysteine-rich with EGF-like domains 2 -0.00487413
PRNP prion protein -0.00482735
EXOC5 exocyst complex component 5 -0.00482732
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00481404
SLPI secretory leukocyte peptidase inhibitor -0.00478451
CAV1 caveolin 1, caveolae protein, 22kDa -0.0047411
SERF2 small EDRK-rich factor 2 -0.00473619
KCTD12 potassium channel tetramerization domain containing 12 -0.00473453
NRN1 neuritin 1 -0.00470505
RPS5 ribosomal protein S5 -0.00469119
CD1B CD1b molecule -0.00466857
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00466478
CD1E CD1e molecule -0.00466252
ACTA1 actin, alpha 1, skeletal muscle -0.0046446
ADGRG6 adhesion G protein-coupled receptor G6 -0.00461892
CRYBG1 crystallin beta-gamma domain containing 1 -0.00458831
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00457981
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00456666
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00454634
AKR1C3 aldo-keto reductase family 1, member C3 -0.00454354
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00454
RPL29 ribosomal protein L29 -0.00453423
SSR4 signal sequence receptor, delta -0.0045296
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00449941
SALL1 spalt-like transcription factor 1 -0.00446988
VNN1 vanin 1 -0.00446558
ACP1 acid phosphatase 1, soluble -0.00446321
DES desmin -0.00446199
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -0.00445791
EXOSC4 exosome component 4 -0.00444744
CAPRIN1 cell cycle associated protein 1 -0.00438512
CDK14 cyclin-dependent kinase 14 -0.00438135
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00436892
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.00435722
CNPY3 canopy FGF signaling regulator 3 -0.00435197
CARD10 caspase recruitment domain family, member 10 -0.00434292
ACKR3 atypical chemokine receptor 3 -0.00432808
INHBE inhibin, beta E -0.00432008
KLF6 Kruppel-like factor 6 -0.00431982
DDIT4 DNA-damage-inducible transcript 4 -0.00430077
TTN titin -0.00429357
RPL35A ribosomal protein L35a -0.00428037
DPYSL2 dihydropyrimidinase-like 2 -0.00422064
HSPA1A heat shock 70kDa protein 1A -0.0042138
STC1 stanniocalcin 1 -0.00417721
CDC123 cell division cycle 123 -0.00417712
SYNGR3 synaptogyrin 3 -0.00416035
AHSG alpha-2-HS-glycoprotein -0.00415949
FXYD2 FXYD domain containing ion transport regulator 2 -0.00414606
HIST1H2AC histone cluster 1, H2ac -0.00414103
TENT5A terminal nucleotidyltransferase 5A -0.00413811
PAH phenylalanine hydroxylase -0.00412658
CD9 CD9 molecule -0.00411312
MYL12B myosin, light chain 12B, regulatory -0.00407658
PERP PERP, TP53 apoptosis effector -0.00407629
LTBP1 latent transforming growth factor beta binding protein 1 -0.00405592
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00402089
THEMIS2 thymocyte selection associated family member 2 -0.00401535
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.00400824
ADIRF adipogenesis regulatory factor -0.00400426
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -0.00399502
MEF2C myocyte enhancer factor 2C -0.0039907
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00398944
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00398494
CCL20 chemokine (C-C motif) ligand 20 -0.00397498
ARG2 arginase 2 -0.00397098
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00396313
HTRA1 HtrA serine peptidase 1 -0.00395983
ORM1 orosomucoid 1 -0.00395787
WIF1 WNT inhibitory factor 1 -0.00395377
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00393559
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00393223
CXADR coxsackie virus and adenovirus receptor -0.00392224
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00392023
CDC42 cell division cycle 42 -0.00391849
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00391379
IL17RB interleukin 17 receptor B -0.00388936
ELOB elongin B -0.00388799
FGR FGR proto-oncogene, Src family tyrosine kinase -0.00388297
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00387425
EIF4A2 eukaryotic translation initiation factor 4A2 -0.00387177
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00385874
BTG2 BTG family, member 2 -0.0038487
FABP7 fatty acid binding protein 7, brain -0.00384236
MGP matrix Gla protein -0.00383784
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00383776
TANK TRAF family member-associated NFKB activator -0.00383337
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -0.00382993
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00382189
CCNG2 cyclin G2 -0.00381635
BAX BCL2-associated X protein -0.00381495
KLF10 Kruppel-like factor 10 -0.00381124
LPP LIM domain containing preferred translocation partner in lipoma -0.00380593
BEX1 brain expressed, X-linked 1 -0.00380198
CLEC5A C-type lectin domain family 5, member A -0.00379322
GLIPR1 GLI pathogenesis-related 1 -0.00377165
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00376765
MCTP1 multiple C2 domains, transmembrane 1 -0.00375604
PFKL phosphofructokinase, liver -0.00373747
CGA glycoprotein hormones, alpha polypeptide -0.0037353
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00373336
TMEM100 transmembrane protein 100 -0.00372848
AGPS alkylglycerone phosphate synthase -0.00372808
CPE carboxypeptidase E -0.00372805
PITX1 paired-like homeodomain 1 -0.00372469
MPZL2 myelin protein zero-like 2 -0.00371991
PTER phosphotriesterase related -0.00371595
CSTA cystatin A (stefin A) -0.00370934
SDC4 syndecan 4 -0.00370103
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00367287
GDI2 GDP dissociation inhibitor 2 -0.00366491
GSTM3 glutathione S-transferase mu 3 (brain) -0.00366372
YIPF5 Yip1 domain family, member 5 -0.00366118
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00365694
KLHL9 kelch-like family member 9 -0.00365466
RPS26 ribosomal protein S26 -0.00364774
RAB4A RAB4A, member RAS oncogene family -0.00364052
EMP1 epithelial membrane protein 1 -0.00363947
PID1 phosphotyrosine interaction domain containing 1 -0.00363663
CDH13 cadherin 13 -0.00363075
OLFM1 olfactomedin 1 -0.00362585
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -0.00361997
OAZ1 ornithine decarboxylase antizyme 1 -0.00361904
LEPROT leptin receptor overlapping transcript -0.00359751
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.00359191
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00358382
FERMT1 fermitin family member 1 -0.00358373
ISG15 ISG15 ubiquitin-like modifier -0.00357551
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00356306
DYNLT3 dynein, light chain, Tctex-type 3 -0.00356284
GPC3 glypican 3 -0.00356157
PDGFC platelet derived growth factor C -0.00354646
CD93 CD93 molecule -0.00353906
RPL14 ribosomal protein L14 -0.00353254
APOC3 apolipoprotein C-III -0.00353205
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.0035297
MARCHF7 membrane associated ring-CH-type finger 7 -0.00351529
SLIT1 slit homolog 1 (Drosophila) -0.00351397
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00350933
NLGN4X neuroligin 4, X-linked -0.00350743
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.0035008
ACAT1 acetyl-CoA acetyltransferase 1 -0.00350026
EDN1 endothelin 1 -0.00349092
VAMP8 vesicle-associated membrane protein 8 -0.00349024
SLC25A46 solute carrier family 25, member 46 -0.00348993
ADAM10 ADAM metallopeptidase domain 10 -0.00348098
ZNF207 zinc finger protein 207 -0.00348014
RAB1A RAB1A, member RAS oncogene family -0.00347798
TSC22D1 TSC22 domain family, member 1 -0.00347578
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.00347375
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00347174
RAB21 RAB21, member RAS oncogene family -0.00346688
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00346398
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00346077
FOXD1 forkhead box D1 -0.00345255
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00345218
ANXA2 annexin A2 -0.00345031
NUMB numb homolog (Drosophila) -0.0034402
FASTKD1 FAST kinase domains 1 -0.00343578
RPL15 ribosomal protein L15 -0.0034347
ARMCX2 armadillo repeat containing, X-linked 2 -0.00341401
C6ORF48 chromosome 6 open reading frame 48 -0.00341265
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -0.00340839
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00340551
SORBS1 sorbin and SH3 domain containing 1 -0.00339118
IL1RAP interleukin 1 receptor accessory protein -0.0033904
ECHDC3 enoyl CoA hydratase domain containing 3 -0.00338296
RSL1D1 ribosomal L1 domain containing 1 -0.0033795
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00337365
OPHN1 oligophrenin 1 -0.00336937
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -0.00336504
GRAMD1C GRAM domain containing 1C -0.00336487
MEX3C mex-3 RNA binding family member C -0.00336413
BTG1 B-cell translocation gene 1, anti-proliferative -0.00336266
TNNC2 troponin C type 2 (fast) -0.00335356
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00335356
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -0.00335109
SLC38A2 solute carrier family 38, member 2 -0.00334692
MED6 mediator complex subunit 6 -0.00334364
NOP53 NOP53 ribosome biogenesis factor -0.00334177
IFI27 interferon, alpha-inducible protein 27 -0.0033341
SF3B5 splicing factor 3b, subunit 5, 10kDa -0.00333194
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -0.00333024
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.003329
CST3 cystatin C -0.0033263
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00332295
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0033193
ERH enhancer of rudimentary homolog (Drosophila) -0.00331357
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00331341
IL1B interleukin 1, beta -0.00330262
PLIN3 perilipin 3 -0.00330047
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00330036
CSTB cystatin B (stefin B) -0.0032982
LIG4 ligase IV, DNA, ATP-dependent -0.00329348
HCK HCK proto-oncogene, Src family tyrosine kinase -0.00329051
PHB prohibitin -0.00328176
ANGPT1 angiopoietin 1 -0.00328063
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.00327997
PTPRK protein tyrosine phosphatase, receptor type, K -0.00327422
BHMT betaine--homocysteine S-methyltransferase -0.00327375
GABPA GA binding protein transcription factor, alpha subunit 60kDa -0.00327061
OPN3 opsin 3 -0.00327013
PCSK2 proprotein convertase subtilisin/kexin type 2 -0.00326074
DERA deoxyribose-phosphate aldolase (putative) -0.00325883
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00325697
CALCRL calcitonin receptor-like -0.00325419
EPCAM epithelial cell adhesion molecule -0.00325389
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0032495
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00324947
CLIC1 chloride intracellular channel 1 -0.00324644