| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/10408514 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in TCS-OX2-29 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TEN1 | TEN1 CST complex subunit | 1.3 |
| SLC26A11 | solute carrier family 26 (anion exchanger), member 11 | 1.13 |
| CROCC2 | ciliary rootlet coiled-coil, rootletin family member 2 | 1.13 |
| PCTP | phosphatidylcholine transfer protein | 0.9 |
| NALCN | sodium leak channel, non selective | 0.83 |
| EPHA4 | EPH receptor A4 | 0.79 |
| ABHD4 | abhydrolase domain containing 4 | 0.7 |
| SEPTIN4 | septin 4 | 0.62 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 0.61 |
| MYH13 | myosin, heavy chain 13, skeletal muscle | 0.6 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.59 |
| RAD54L | RAD54-like (S. cerevisiae) | 0.58 |
| RAB27B | RAB27B, member RAS oncogene family | 0.58 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | 0.53 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.52 |
| CEP72 | centrosomal protein 72kDa | 0.52 |
| ALPK3 | alpha-kinase 3 | 0.47 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.44 |
| KLHL29 | kelch-like family member 29 | 0.44 |
| SLC30A6 | solute carrier family 30 (zinc transporter), member 6 | 0.43 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.42 |
| ZNF224 | zinc finger protein 224 | 0.41 |
| CENPH | centromere protein H | 0.41 |
| NAA80 | N-alpha-acetyltransferase 80, NatH catalytic subunit | 0.4 |
| RNF146 | ring finger protein 146 | 0.4 |
| ZNF136 | zinc finger protein 136 | 0.39 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.39 |
| FJX1 | four jointed box 1 (Drosophila) | 0.36 |
| ZFP37 | ZFP37 zinc finger protein | 0.36 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.36 |
| MFSD6 | major facilitator superfamily domain containing 6 | 0.35 |
| FCHO1 | FCH domain only 1 | 0.35 |
| ZDHHC23 | zinc finger, DHHC-type containing 23 | 0.34 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 0.33 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.32 |
| MAGEA2 | melanoma antigen family A2 | 0.32 |
| MYZAP | myocardial zonula adherens protein | 0.31 |
| AUNIP | aurora kinase A and ninein interacting protein | 0.31 |
| SET | SET nuclear proto-oncogene | 0.3 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.3 |
| ELFN1 | extracellular leucine-rich repeat and fibronectin type III domain containing 1 | 0.3 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | 0.3 |
| GLMP | glycosylated lysosomal membrane protein | 0.3 |
| DESI2 | desumoylating isopeptidase 2 | 0.29 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 | 0.29 |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 | 0.29 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.29 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.28 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.28 |
| PON3 | paraoxonase 3 | 0.28 |
| DDN | dendrin | 0.28 |
| HIST2H2BC | histone cluster 2, H2bc (pseudogene) | 0.28 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | 0.28 |
| RPL36AL | ribosomal protein L36a-like | 0.28 |
| TMEM222 | transmembrane protein 222 | 0.27 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.27 |
| ERICH1 | glutamate-rich 1 | 0.27 |
| CCDC15 | coiled-coil domain containing 15 | 0.27 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | 0.27 |
| USP28 | ubiquitin specific peptidase 28 | 0.26 |
| ZBTB4 | zinc finger and BTB domain containing 4 | 0.26 |
| NOL12 | nucleolar protein 12 | 0.26 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.26 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.26 |
| IER5 | immediate early response 5 | 0.25 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | 0.25 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 0.25 |
| LMX1B | LIM homeobox transcription factor 1, beta | 0.25 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.25 |
| TRIM62 | tripartite motif containing 62 | 0.25 |
| PEX12 | peroxisomal biogenesis factor 12 | 0.25 |
| RMDN2 | regulator of microtubule dynamics 2 | 0.25 |
| RUNDC1 | RUN domain containing 1 | 0.24 |
| CCDC9B | coiled-coil domain containing 9B | 0.24 |
| CKM | creatine kinase, muscle | 0.24 |
| SVBP | small vasohibin binding protein | 0.24 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.24 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.24 |
| ARSK | arylsulfatase family, member K | 0.24 |
| MCOLN1 | mucolipin 1 | 0.24 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.24 |
| ZNF395 | zinc finger protein 395 | 0.24 |
| LMLN | leishmanolysin-like (metallopeptidase M8 family) | 0.24 |
| RNF4 | ring finger protein 4 | 0.24 |
| ZNF669 | zinc finger protein 669 | 0.23 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.23 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.23 |
| WDR20 | WD repeat domain 20 | 0.23 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.23 |
| C4ORF33 | chromosome 4 open reading frame 33 | 0.23 |
| RTN4RL2 | reticulon 4 receptor-like 2 | 0.23 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.23 |
| HES1 | hes family bHLH transcription factor 1 | 0.22 |
| SESN1 | sestrin 1 | 0.22 |
| GPN3 | GPN-loop GTPase 3 | 0.22 |
| OSCP1 | organic solute carrier partner 1 | 0.22 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | 0.22 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.22 |
| CAV2 | caveolin 2 | 0.22 |
| ETV3 | ets variant 3 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.71 |
| MAGEA12 | melanoma antigen family A12 | -0.68 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.68 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.68 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | -0.6 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.59 |
| VIM | vimentin | -0.55 |
| EVL | Enah/Vasp-like | -0.5 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.48 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.47 |
| GGACT | gamma-glutamylamine cyclotransferase | -0.46 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.46 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.45 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.42 |
| PIP | prolactin-induced protein | -0.42 |
| DNAH9 | dynein, axonemal, heavy chain 9 | -0.4 |
| BCO2 | beta-carotene oxygenase 2 | -0.39 |
| ZNF444 | zinc finger protein 444 | -0.39 |
| ZNF362 | zinc finger protein 362 | -0.39 |
| GLRX | glutaredoxin (thioltransferase) | -0.38 |
| DCLRE1A | DNA cross-link repair 1A | -0.38 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.38 |
| TSPYL2 | TSPY-like 2 | -0.38 |
| SH2B3 | SH2B adaptor protein 3 | -0.38 |
| SVIP | small VCP/p97-interacting protein | -0.37 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.36 |
| ZNF33A | zinc finger protein 33A | -0.36 |
| PPP1R2B | PPP1R2 family member B | -0.36 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.35 |
| COL6A3 | collagen, type VI, alpha 3 | -0.35 |
| C18ORF32 | chromosome 18 open reading frame 32 | -0.35 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.34 |
| ZNF805 | zinc finger protein 805 | -0.34 |
| ZNF22 | zinc finger protein 22 | -0.34 |
| TMEM41B | transmembrane protein 41B | -0.33 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.33 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | -0.33 |
| ZNF711 | zinc finger protein 711 | -0.33 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin | -0.32 |
| SDHAF4 | succinate dehydrogenase complex assembly factor 4 | -0.32 |
| KLF2 | Kruppel-like factor 2 | -0.32 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.32 |
| CPN1 | carboxypeptidase N, polypeptide 1 | -0.32 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 | -0.31 |
| SMTN | smoothelin | -0.31 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.31 |
| COX19 | COX19 cytochrome c oxidase assembly factor | -0.31 |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | -0.31 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.31 |
| SELENOK | selenoprotein K | -0.31 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.3 |
| KIAA1958 | KIAA1958 | -0.3 |
| ERMARD | ER membrane-associated RNA degradation | -0.29 |
| ATP9A | ATPase, class II, type 9A | -0.29 |
| BSDC1 | BSD domain containing 1 | -0.29 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.29 |
| NRXN3 | neurexin 3 | -0.28 |
| ATE1 | arginyltransferase 1 | -0.28 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | -0.28 |
| NFYB | nuclear transcription factor Y, beta | -0.28 |
| CFAP410 | cilia and flagella associated protein 410 | -0.28 |
| MRPL52 | mitochondrial ribosomal protein L52 | -0.27 |
| MT1X | metallothionein 1X | -0.27 |
| ZNF503 | zinc finger protein 503 | -0.27 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -0.27 |
| NRBF2 | nuclear receptor binding factor 2 | -0.27 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | -0.27 |
| KMT5B | lysine methyltransferase 5B | -0.27 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | -0.27 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | -0.26 |
| UPRT | uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) | -0.26 |
| YAE1 | YAE1 maturation factor of ABCE1 | -0.26 |
| SNAP23 | synaptosomal-associated protein, 23kDa | -0.26 |
| S100A3 | S100 calcium binding protein A3 | -0.26 |
| CSNK1A1L | casein kinase 1, alpha 1-like | -0.25 |
| KLK7 | kallikrein-related peptidase 7 | -0.25 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -0.25 |
| KPTN | kaptin (actin binding protein) | -0.25 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.25 |
| SPATA33 | spermatogenesis associated 33 | -0.25 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | -0.24 |
| ZNF658 | zinc finger protein 658 | -0.24 |
| TESC | tescalcin | -0.24 |
| STC2 | stanniocalcin 2 | -0.24 |
| ZNF766 | zinc finger protein 766 | -0.24 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.24 |
| EXPH5 | exophilin 5 | -0.24 |
| MT1L | metallothionein 1L (gene/pseudogene) | -0.24 |
| WTAP | Wilms tumor 1 associated protein | -0.24 |
| TMEM161B | transmembrane protein 161B | -0.24 |
| C1ORF52 | chromosome 1 open reading frame 52 | -0.24 |
| LRP1 | low density lipoprotein receptor-related protein 1 | -0.24 |
| SESN2 | sestrin 2 | -0.23 |
| SGCE | sarcoglycan, epsilon | -0.23 |
| SRRD | SRR1 domain containing | -0.23 |
| TSC22D4 | TSC22 domain family, member 4 | -0.23 |
| ARSD | arylsulfatase D | -0.23 |
| SGTB | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta | -0.23 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.23 |
| ANGPTL4 | angiopoietin-like 4 | -0.22 |
