| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | thymine-DNA glycosylase|The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6996) |
| External Link | https://ncbi.nlm.nih.gov/gene/6996 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the TDG gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT17 | keratin 17, type I | 0.0171839 |
| HSPA1A | heat shock 70kDa protein 1A | 0.016863 |
| MX1 | MX dynamin-like GTPase 1 | 0.0164942 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0156203 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0147217 |
| KRT14 | keratin 14, type I | 0.014602 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0143423 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0142502 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0140116 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0139213 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0136217 |
| HSPB8 | heat shock 22kDa protein 8 | 0.0133189 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0132753 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.0132177 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0129999 |
| GAB2 | GRB2-associated binding protein 2 | 0.0126633 |
| MAGEA3 | melanoma antigen family A3 | 0.0125341 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.012341 |
| SPRR3 | small proline-rich protein 3 | 0.0120338 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0119105 |
| ASS1 | argininosuccinate synthase 1 | 0.0116979 |
| KRT7 | keratin 7, type II | 0.0116307 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0113721 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0112169 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0111854 |
| CTSZ | cathepsin Z | 0.0109936 |
| S100A7 | S100 calcium binding protein A7 | 0.0109304 |
| CCN2 | cellular communication network factor 2 | 0.0107455 |
| SPRR2B | small proline-rich protein 2B | 0.0107025 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.0106707 |
| NDNF | neuron-derived neurotrophic factor | 0.0106401 |
| BAG3 | BCL2-associated athanogene 3 | 0.0105769 |
| IRS2 | insulin receptor substrate 2 | 0.0105353 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0105262 |
| IFI44L | interferon-induced protein 44-like | 0.0105157 |
| S100P | S100 calcium binding protein P | 0.0105125 |
| IFI44 | interferon-induced protein 44 | 0.010413 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0104044 |
| EGR1 | early growth response 1 | 0.0103951 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.0103743 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0103387 |
| S100A11 | S100 calcium binding protein A11 | 0.010328 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0102917 |
| INAVA | innate immunity activator | 0.0102916 |
| LAMB3 | laminin, beta 3 | 0.0102828 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.0102734 |
| ABLIM1 | actin binding LIM protein 1 | 0.0100364 |
| RBM47 | RNA binding motif protein 47 | 0.0100151 |
| EFNA1 | ephrin-A1 | 0.00990421 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00982765 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00966015 |
| LAMC2 | laminin, gamma 2 | 0.00954273 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00952829 |
| MGLL | monoglyceride lipase | 0.00949572 |
| KRT15 | keratin 15, type I | 0.00942867 |
| SIK1 | salt-inducible kinase 1 | 0.00936989 |
| INSR | insulin receptor | 0.00936004 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.009311 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00927125 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00919983 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00916602 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00906414 |
| SPRR1B | small proline-rich protein 1B | 0.00905025 |
| ANXA3 | annexin A3 | 0.00904661 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00902005 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0090119 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00896226 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00889111 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00880544 |
| HMOX1 | heme oxygenase 1 | 0.0087993 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00877607 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00877318 |
| PON3 | paraoxonase 3 | 0.0087124 |
| EGR2 | early growth response 2 | 0.0086929 |
| RRAD | Ras-related associated with diabetes | 0.00862692 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00860877 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00858834 |
| MVP | major vault protein | 0.00852441 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00851512 |
| KRT16 | keratin 16, type I | 0.00848088 |
| IL32 | interleukin 32 | 0.00843743 |
| PLK2 | polo-like kinase 2 | 0.008416 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00840446 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00838848 |
| EZR | ezrin | 0.00834563 |
| MYOF | myoferlin | 0.00834243 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00831961 |
| TNNC1 | troponin C type 1 (slow) | 0.0082972 |
| MMP10 | matrix metallopeptidase 10 | 0.00828877 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00827551 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0082667 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00826008 |
| KLK10 | kallikrein-related peptidase 10 | 0.00823194 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00822157 |
| NELL2 | NEL-like 2 (chicken) | 0.00820042 |
| MAGEA4 | melanoma antigen family A4 | 0.00818592 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00817768 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00816679 |
| NEFH | neurofilament, heavy polypeptide | 0.00815483 |
| COL1A1 | collagen, type I, alpha 1 | 0.00815387 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00815203 |
| OXTR | oxytocin receptor | 0.00812895 |
| SPRR1A | small proline-rich protein 1A | 0.00810959 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.008065 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00806229 |
| CD93 | CD93 molecule | 0.0080269 |
| IL1B | interleukin 1, beta | 0.00799852 |
| TRIM29 | tripartite motif containing 29 | 0.00792135 |
| WWC1 | WW and C2 domain containing 1 | 0.00791699 |
| CLIC4 | chloride intracellular channel 4 | 0.00791565 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00790409 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00789176 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00788441 |
| MYO1B | myosin IB | 0.00786013 |
| TP63 | tumor protein p63 | 0.00780526 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00780236 |
| ATF3 | activating transcription factor 3 | 0.00779441 |
| PXDN | peroxidasin | 0.00777561 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00775178 |
| DAPK1 | death-associated protein kinase 1 | 0.00774533 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00772567 |
| S100A12 | S100 calcium binding protein A12 | 0.00772145 |
| JAK1 | Janus kinase 1 | 0.00767625 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00767109 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00766787 |
| MAGEA12 | melanoma antigen family A12 | 0.00766509 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00765678 |
| MMP7 | matrix metallopeptidase 7 | 0.00763948 |
| PALLD | palladin, cytoskeletal associated protein | 0.00763666 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00763533 |
| KLF6 | Kruppel-like factor 6 | 0.0076302 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00760093 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00759442 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0075901 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00757387 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00756689 |
| PODXL | podocalyxin-like | 0.00752979 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00750827 |
| CDA | cytidine deaminase | 0.00748179 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00747593 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00746098 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0074559 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00742418 |
| ITGA6 | integrin, alpha 6 | 0.00741265 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00740163 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.00739212 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.00739149 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00738849 |
| KYNU | kynureninase | 0.00738658 |
| RIN3 | Ras and Rab interactor 3 | 0.0073843 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00738191 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00736179 |
| RNASET2 | ribonuclease T2 | 0.0073607 |
| CES1 | carboxylesterase 1 | 0.00735091 |
| CSTB | cystatin B (stefin B) | 0.00734392 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.0073365 |
| DUSP5 | dual specificity phosphatase 5 | 0.00733126 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00731107 |
| MALL | mal, T-cell differentiation protein-like | 0.00728448 |
| LAMA2 | laminin, alpha 2 | 0.00727903 |
| IL36G | interleukin 36, gamma | 0.00726594 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00724894 |
| S100A8 | S100 calcium binding protein A8 | 0.00724847 |
| TDRD7 | tudor domain containing 7 | 0.0071924 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00719076 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00718485 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00718121 |
| GSN | gelsolin | 0.00716912 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00714098 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0071288 |
| HECA | headcase homolog (Drosophila) | 0.00711806 |
| SQSTM1 | sequestosome 1 | 0.00711788 |
| PRNP | prion protein | 0.00711022 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.0071098 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00709454 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00708188 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00706683 |
| SETD5 | SET domain containing 5 | 0.00705521 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00705034 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00704458 |
| FHL2 | four and a half LIM domains 2 | 0.00703363 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00702083 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00702045 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00700315 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00700139 |
| BRD4 | bromodomain containing 4 | 0.00699635 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0069644 |
| S100A9 | S100 calcium binding protein A9 | 0.00696433 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.00692993 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.00692934 |
| RUNX3 | runt-related transcription factor 3 | 0.00692745 |
| IL6 | interleukin 6 | 0.00692135 |
| SPAG1 | sperm associated antigen 1 | 0.00691107 |
| CTTN | cortactin | 0.0069107 |
| AIM2 | absent in melanoma 2 | 0.00690573 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00689535 |
| IL1RN | interleukin 1 receptor antagonist | 0.00688224 |
| ANXA1 | annexin A1 | 0.00686334 |
| KRT23 | keratin 23, type I | 0.00686232 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00685579 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00685469 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00685311 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00684537 |
| DUSP4 | dual specificity phosphatase 4 | 0.0068205 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00681485 |
| MAGEA1 | melanoma antigen family A1 | 0.00680518 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00680458 |
| SCEL | sciellin | 0.006801 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00678936 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00677325 |
| NXN | nucleoredoxin | 0.00677146 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00676317 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00669949 |
| TMEM135 | transmembrane protein 135 | 0.00667858 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00667421 |
| NAGK | N-acetylglucosamine kinase | 0.00665978 |
| TGFA | transforming growth factor, alpha | 0.00665165 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00662538 |
| SP100 | SP100 nuclear antigen | 0.00662086 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00661912 |
| FOSL2 | FOS-like antigen 2 | 0.00661761 |
| EPS8L2 | EPS8-like 2 | 0.00661341 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00660779 |
| YBX3 | Y box binding protein 3 | 0.00659761 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00659594 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00659371 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.00658808 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00656492 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00654125 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00653177 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00652858 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.00649719 |
| ADI1 | acireductone dioxygenase 1 | 0.0064759 |
| RHOF | ras homolog family member F (in filopodia) | 0.0064755 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00647382 |
| NAV2 | neuron navigator 2 | 0.00647304 |
| SMAD3 | SMAD family member 3 | 0.0064697 |
| IRF9 | interferon regulatory factor 9 | 0.00643099 |
| RBM5 | RNA binding motif protein 5 | 0.0064285 |
| CRYAB | crystallin, alpha B | 0.00642696 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00641565 |
| CUX1 | cut-like homeobox 1 | 0.00640951 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00640819 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00640364 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00638618 |
| CORO1C | coronin, actin binding protein, 1C | 0.00637951 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00636692 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0063658 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0063606 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.0149997 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0143718 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0141552 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0140853 |
| MMP9 | matrix metallopeptidase 9 | -0.0135443 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0134455 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.0129725 |
| LYZ | lysozyme | -0.01218 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0120474 |
| CHEK2 | checkpoint kinase 2 | -0.0116975 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0111948 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0109377 |
| METTL7A | methyltransferase like 7A | -0.0108837 |
| CRIP2 | cysteine-rich protein 2 | -0.0105971 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.0104444 |
| NPY | neuropeptide Y | -0.0102748 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.0102694 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00999017 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00995781 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00991463 |
| RPA3 | replication protein A3, 14kDa | -0.00961546 |
| NNMT | nicotinamide N-methyltransferase | -0.00958808 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00958549 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00954169 |
| CST3 | cystatin C | -0.0095321 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00948451 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0093368 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00931939 |
| TMSB15A | thymosin beta 15a | -0.0092281 |
| TXNIP | thioredoxin interacting protein | -0.00920415 |
| REG3A | regenerating islet-derived 3 alpha | -0.00901266 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00897583 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0088606 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.00884219 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00875559 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00874631 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00868202 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00868086 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00859415 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00845162 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00839322 |
| TMEM38B | transmembrane protein 38B | -0.00836153 |
| NTS | neurotensin | -0.00833327 |
| PCP4 | Purkinje cell protein 4 | -0.00832205 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00830347 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00827963 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00827674 |
| HMGB3 | high mobility group box 3 | -0.00824549 |
| ERLIN2 | ER lipid raft associated 2 | -0.00824377 |
| TMEM14B | transmembrane protein 14B | -0.00822726 |
| FAM3C | family with sequence similarity 3, member C | -0.00817466 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00815709 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00814788 |
| PTK2 | protein tyrosine kinase 2 | -0.00812877 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00812298 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00809279 |
| PTTG1 | pituitary tumor-transforming 1 | -0.00804332 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00801204 |
| TMEM165 | transmembrane protein 165 | -0.00792691 |
| GAS1 | growth arrest-specific 1 | -0.00780815 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00779872 |
| CLCA1 | chloride channel accessory 1 | -0.00773087 |
| H2AX | H2A.X variant histone | -0.00771 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00769875 |
| RPS5 | ribosomal protein S5 | -0.00769393 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00764126 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00762564 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00759762 |
| CST7 | cystatin F (leukocystatin) | -0.0075925 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00757538 |
| KLF10 | Kruppel-like factor 10 | -0.00757269 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00754503 |
| HPF1 | histone PARylation factor 1 | -0.0074605 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -0.00745034 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00743719 |
| LEFTY1 | left-right determination factor 1 | -0.00742611 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00742084 |
| DDHD2 | DDHD domain containing 2 | -0.00741812 |
| REG1A | regenerating islet-derived 1 alpha | -0.00740478 |
| THY1 | Thy-1 cell surface antigen | -0.00739264 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00736583 |
| ZNF329 | zinc finger protein 329 | -0.00735285 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00734888 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00734014 |
| RTN1 | reticulon 1 | -0.00731897 |
| CD320 | CD320 molecule | -0.00730738 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00729991 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00728993 |
| FASN | fatty acid synthase | -0.00724554 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00724227 |
| VDAC3 | voltage-dependent anion channel 3 | -0.00721205 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00718561 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00718153 |
| CDC20 | cell division cycle 20 | -0.00713411 |
| MAGT1 | magnesium transporter 1 | -0.00712805 |
| FAM162A | family with sequence similarity 162, member A | -0.00709102 |
| NRN1 | neuritin 1 | -0.0070782 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0070709 |
| LOX | lysyl oxidase | -0.00706248 |
| RGS1 | regulator of G-protein signaling 1 | -0.00705385 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00704978 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00701962 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00701434 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00700211 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00699948 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00698201 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00697961 |
| PLK1 | polo-like kinase 1 | -0.00697647 |
| THYN1 | thymocyte nuclear protein 1 | -0.00697639 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00696831 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00696313 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00694907 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00694408 |
| PITX3 | paired-like homeodomain 3 | -0.00694407 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00693908 |
| WDR61 | WD repeat domain 61 | -0.00692279 |
| ACTL6A | actin-like 6A | -0.0069163 |
| CENPX | centromere protein X | -0.00689613 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00689156 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | -0.00688652 |
| TSPAN7 | tetraspanin 7 | -0.00687876 |
| PCYOX1L | prenylcysteine oxidase 1 like | -0.00687791 |
| RAB13 | RAB13, member RAS oncogene family | -0.00687615 |
| TOB1 | transducer of ERBB2, 1 | -0.00685426 |
| ANO3 | anoctamin 3 | -0.00684323 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00683888 |
| CCNB2 | cyclin B2 | -0.00682423 |
| TMEM106C | transmembrane protein 106C | -0.00681911 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00679734 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | -0.00676496 |
| CCNB1 | cyclin B1 | -0.00675368 |
| COMMD8 | COMM domain containing 8 | -0.00672776 |
| TRMT5 | tRNA methyltransferase 5 | -0.00669814 |
| RGS4 | regulator of G-protein signaling 4 | -0.00667719 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00667503 |
| ADIRF | adipogenesis regulatory factor | -0.00667263 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.00666964 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00665277 |
| CCNF | cyclin F | -0.00664747 |
| CCNE2 | cyclin E2 | -0.00663151 |
| IFT27 | intraflagellar transport 27 | -0.00662571 |
| PLPBP | pyridoxal phosphate binding protein | -0.00661279 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00658786 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00655343 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | -0.00654396 |
| RPA2 | replication protein A2, 32kDa | -0.00653036 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00652239 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00651078 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00646034 |
| FABP1 | fatty acid binding protein 1, liver | -0.00643327 |
| TMEM47 | transmembrane protein 47 | -0.00642971 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00642636 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00639777 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00637275 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00636065 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00635243 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00635168 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00634329 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00633994 |
| PLEK | pleckstrin | -0.00633656 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -0.00633529 |
| TMEM106B | transmembrane protein 106B | -0.00633409 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00632878 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00632241 |
| C11ORF71 | chromosome 11 open reading frame 71 | -0.0063149 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00631135 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00630064 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00629451 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | -0.0062872 |
| ATF1 | activating transcription factor 1 | -0.00626869 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00625983 |
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | -0.00624633 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00623906 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.00622858 |
| DEK | DEK proto-oncogene | -0.00622777 |
| ASPH | aspartate beta-hydroxylase | -0.00622669 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00622117 |
| JMJD6 | jumonji domain containing 6 | -0.00621106 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00619527 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00618004 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00617969 |
| H1-0 | H1.0 linker histone | -0.00617866 |
| CD2 | CD2 molecule | -0.00617763 |
| CHN2 | chimerin 2 | -0.00617513 |
| FAM234B | family with sequence similarity 234 member B | -0.00614566 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00611097 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00609334 |
| APMAP | adipocyte plasma membrane associated protein | -0.00607882 |
| OIP5 | Opa interacting protein 5 | -0.00607684 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00607241 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00604978 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00604831 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00604302 |
| LEPR | leptin receptor | -0.00603329 |
| MT3 | metallothionein 3 | -0.00602594 |
| PIMREG | PICALM interacting mitotic regulator | -0.00601713 |
| INSIG1 | insulin induced gene 1 | -0.00601035 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00600899 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.00600432 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00600223 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00596766 |
| CDCA4 | cell division cycle associated 4 | -0.00594234 |
| PRDX3 | peroxiredoxin 3 | -0.00593483 |
| PRKD3 | protein kinase D3 | -0.0059342 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | -0.00592426 |
| ADSL | adenylosuccinate lyase | -0.00591923 |
| DUT | deoxyuridine triphosphatase | -0.00591522 |
| CTSK | cathepsin K | -0.00591462 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00590876 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.005908 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00590349 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) | -0.00590192 |
| TUBA1A | tubulin, alpha 1a | -0.00590024 |
| LYPLA1 | lysophospholipase I | -0.00589519 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | -0.00589399 |
| GCAT | glycine C-acetyltransferase | -0.00589359 |
| F12 | coagulation factor XII (Hageman factor) | -0.00588637 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00588103 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00585773 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00585299 |
| NEK2 | NIMA-related kinase 2 | -0.00585028 |
| MRPS27 | mitochondrial ribosomal protein S27 | -0.00584997 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | -0.00583168 |
| COPS4 | COP9 signalosome subunit 4 | -0.00582864 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.00582118 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0058112 |
| HELLS | helicase, lymphoid-specific | -0.00580625 |
| ABHD10 | abhydrolase domain containing 10 | -0.00578186 |
| APOC2 | apolipoprotein C-II | -0.00577899 |
| PLS3 | plastin 3 | -0.00577659 |
| DHFR | dihydrofolate reductase | -0.00577229 |
| SDC2 | syndecan 2 | -0.00576553 |
| DCK | deoxycytidine kinase | -0.00575991 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00574935 |
| TBPL1 | TBP-like 1 | -0.00574707 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00574451 |
| CRYL1 | crystallin, lambda 1 | -0.00573863 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | -0.00572259 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00571906 |
| WBP5 | WW domain binding protein 5 | -0.00571659 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00569529 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.00568922 |
| PLA2G12A | phospholipase A2, group XIIA | -0.00568797 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00568113 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00568007 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00565667 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00564986 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 | -0.00564559 |
| HMGB2 | high mobility group box 2 | -0.00564432 |
| MORF4L1 | mortality factor 4 like 1 | -0.00564021 |
