TDP2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description tyrosyl-DNA phosphodiesterase 2|This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 51567)
External Link http://www.ncbi.nlm.nih.gov/gene/51567
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Genes

37 interacting proteins for TDP2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACVR1B activin A receptor, type IB
AKAP9 A kinase (PRKA) anchor protein 9
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATXN1 ataxin 1
C2ORF88 chromosome 2 open reading frame 88
CD40 CD40 molecule, TNF receptor superfamily member 5
DLX3 distal-less homeobox 3
EPS8 epidermal growth factor receptor pathway substrate 8
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
HNF4A hepatocyte nuclear factor 4, alpha
JAM2 junctional adhesion molecule 2
MAPK6 mitogen-activated protein kinase 6
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRF1 nuclear respiratory factor 1
PARK7 parkinson protein 7
PSEN1 presenilin 1
RAB11A RAB11A, member RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SKIL SKI-like proto-oncogene
SMAD3 SMAD family member 3
SNX13 sorting nexin 13
SRPK2 SRSF protein kinase 2
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I