TE-1 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer. Squamous cell carcinoma. TKG0462(Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051369)
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Genes

274 genes with high or low expression in TE-1 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 3.36134
UBE2L3 ubiquitin-conjugating enzyme E2L 3 3.27361
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 3.18625
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2.9383
USP39 ubiquitin specific peptidase 39 2.82718
CENPA centromere protein A 2.71587
FAM149B1 family with sequence similarity 149, member B1 2.71039
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 2.64862
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 2.6062
MAPK1 mitogen-activated protein kinase 1 2.59802
IMMT inner membrane protein, mitochondrial 2.58592
PUM2 pumilio RNA-binding family member 2 2.58114
KLHL7 kelch-like family member 7 2.57773
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.552
AGMAT agmatine ureohydrolase (agmatinase) 2.51591
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 2.50626
ECD ecdysoneless homolog (Drosophila) 2.46383
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.45411
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 2.31894
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 2.27835
TSLIG3A tRNA splicing ligase complex subunit 3A 2.26924
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2.24674
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.21064
SNAP29 synaptosomal-associated protein, 29kDa 2.19049
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.18968
STRN striatin, calmodulin binding protein 2.16906
PCSK6 proprotein convertase subtilisin/kexin type 6 2.15636
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 2.14355
YIPF4 Yip1 domain family, member 4 2.13849
MICU1 mitochondrial calcium uptake 1 2.12106
UFD1L ubiquitin fusion degradation 1 like (yeast) 2.09575
THOC1 THO complex 1 2.08717
KIF1BP KIF1 binding protein 2.08283
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.07773
ATF7IP activating transcription factor 7 interacting protein 2.07231
PPBPP2 pro-platelet basic protein pseudogene 2 2.05489
CHMP3 charged multivesicular body protein 3 2.04886
S1PR5 sphingosine-1-phosphate receptor 5 2.04049
H2AFV H2A histone family, member V 2.0233
TWSG1 twisted gastrulation BMP signaling modulator 1 1.99958
LOC647070 uncharacterized LOC647070 1.99135
KLK5 kallikrein-related peptidase 5 1.98276
CKAP2 cytoskeleton associated protein 2 1.97359
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 1.9625
KITLG KIT ligand 1.94454
CCDC6 coiled-coil domain containing 6 1.93559
ASXL2 additional sex combs like transcriptional regulator 2 1.93454
COL8A2 collagen, type VIII, alpha 2 1.93284
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.92099
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 1.91016
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.90816
KPNA3 karyopherin alpha 3 (importin alpha 4) 1.90105
KDM1A lysine (K)-specific demethylase 1A 1.86773
EGR4 early growth response 4 1.86409
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.8638
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 1.84391
RANBP1 RAN binding protein 1 1.82912
MSH2 mutS homolog 2 1.82562
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.81604
KLK6 kallikrein-related peptidase 6 1.8089
CDC45 cell division cycle 45 1.80841
DBF4 DBF4 zinc finger 1.80426
THUMPD2 THUMP domain containing 2 1.80404
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 1.80299
HIST1H4A histone cluster 1, H4a 1.7888
TEX2 testis expressed 2 1.78636
MCFD2 multiple coagulation factor deficiency 2 1.78129
STOML2 stomatin (EPB72)-like 2 1.7812
SLC25A40 solute carrier family 25, member 40 1.78113
IVNS1ABP influenza virus NS1A binding protein 1.77939
KIAA0895 KIAA0895 1.77401
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.77128
GLO1 glyoxalase I 1.76945
ACTL8 actin-like 8 1.76064
HPCAL4 hippocalcin like 4 1.75293
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C 1.7381
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.72645
RPA3 replication protein A3, 14kDa 1.7199
HMGN4 high mobility group nucleosomal binding domain 4 1.70971
LRPPRC leucine-rich pentatricopeptide repeat containing 1.70944
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 1.708
HP1BP3 heterochromatin protein 1, binding protein 3 1.69468
ANKRD6 ankyrin repeat domain 6 1.6764
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.66931
MAPK8 mitogen-activated protein kinase 8 1.65037
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.63919
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.63558
SNX13 sorting nexin 13 1.62618
HIST1H2BI histone cluster 1, H2bi 1.62353
SAR1A secretion associated, Ras related GTPase 1A 1.61946
TMOD2 tropomodulin 2 (neuronal) 1.60969
HIST2H2BE histone cluster 2, H2be 1.60814
FANCG Fanconi anemia, complementation group G 1.60757
ALX3 ALX homeobox 3 1.59701
TTC26 tetratricopeptide repeat domain 26 1.59616
FABP3 fatty acid binding protein 3, muscle and heart 1.59215
NUPL2 nucleoporin like 2 1.58373
CRIPT cysteine-rich PDZ-binding protein 1.58083
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.57254
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 1.56134
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 1.55968
HSPA2 heat shock 70kDa protein 2 1.54739
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 1.54513
GABARAPL1 GABA(A) receptor-associated protein like 1 1.53764
PTPN14 protein tyrosine phosphatase, non-receptor type 14 1.53326
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.52981
S100A10 S100 calcium binding protein A10 1.52161
KLHL12 kelch-like family member 12 1.51914
MSH6 mutS homolog 6 1.51786
NCBP1 nuclear cap binding protein subunit 1, 80kDa 1.51784
MELK maternal embryonic leucine zipper kinase 1.51052
INSL6 insulin-like 6 1.51009
CBY1 chibby homolog 1 (Drosophila) 1.50072
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.49824
GUCY2F guanylate cyclase 2F, retinal 1.49338
GPR20 G protein-coupled receptor 20 1.49263
HIST1H2AM histone cluster 1, H2am 1.48774
MAN1A2 mannosidase, alpha, class 1A, member 2 1.48098
TUBB6 tubulin, beta 6 class V 1.47918
PDYN prodynorphin 1.47759
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.47673
CEP192 centrosomal protein 192kDa 1.47591
MTAP methylthioadenosine phosphorylase 1.47486
ANKRD53 ankyrin repeat domain 53 1.46976
PITPNM3 PITPNM family member 3 1.46952
GPSM2 G-protein signaling modulator 2 1.46869
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.46797
PON3 paraoxonase 3 1.46496
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 1.46474
NCOA4 nuclear receptor coactivator 4 1.45908
SUMO1 small ubiquitin-like modifier 1 1.45881
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 1.45713
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.45503
OLFML3 olfactomedin-like 3 1.45362
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.44688
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.44682
ARSF arylsulfatase F 1.44674
MRPL33 mitochondrial ribosomal protein L33 1.43865
VAMP8 vesicle-associated membrane protein 8 1.43625
UBAC1 UBA domain containing 1 1.43134
FMO4 flavin containing monooxygenase 4 1.42531
PCDH7 protocadherin 7 1.42374
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.42253
FASTKD3 FAST kinase domains 3 1.42162

low expression

Symbol Name Standardized Value
ARFIP1 ADP-ribosylation factor interacting protein 1 -3.53725
ASMTL acetylserotonin O-methyltransferase-like -2.9966
GANAB glucosidase, alpha; neutral AB -2.93147
B3GAT3 beta-1,3-glucuronyltransferase 3 -2.89816
TMF1 TATA element modulatory factor 1 -2.86662
GOLGA7 golgin A7 -2.83244
KAT6A K(lysine) acetyltransferase 6A -2.72099
ZBTB40 zinc finger and BTB domain containing 40 -2.71549
ZNF764 zinc finger protein 764 -2.69546
VDAC3 voltage-dependent anion channel 3 -2.69348
BGLAP bone gamma-carboxyglutamate (gla) protein -2.69118
ADGRB3 adhesion G protein-coupled receptor B3 -2.64997
DEAF1 DEAF1 transcription factor -2.64331
ACVR2B activin A receptor, type IIB -2.62127
UQCRB ubiquinol-cytochrome c reductase binding protein -2.58689
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -2.57914
TSSC4 tumor suppressing subtransferable candidate 4 -2.51897
CCDC59 coiled-coil domain containing 59 -2.43836
ZFHX4 zinc finger homeobox 4 -2.4135
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -2.39822
ZNF268 zinc finger protein 268 -2.3943
TCF25 transcription factor 25 (basic helix-loop-helix) -2.37539
LARP1 La ribonucleoprotein domain family, member 1 -2.37073
MUS81 MUS81 structure-specific endonuclease subunit -2.3431
POLB polymerase (DNA directed), beta -2.25717
CLCN6 chloride channel, voltage-sensitive 6 -2.1977
ZNF140 zinc finger protein 140 -2.1667
CD3D CD3d molecule, delta (CD3-TCR complex) -2.15465
LRRC6 leucine rich repeat containing 6 -2.14084
CEND1 cell cycle exit and neuronal differentiation 1 -2.13923
RANBP10 RAN binding protein 10 -2.11358
OSBP oxysterol binding protein -2.10989
ZBTB22 zinc finger and BTB domain containing 22 -2.10011
CLK3 CDC-like kinase 3 -2.08727
KAT5 K(lysine) acetyltransferase 5 -2.07332
PTDSS2 phosphatidylserine synthase 2 -2.02071
CDKL3 cyclin-dependent kinase-like 3 -2.00753
TBP TATA box binding protein -1.98872
PWWP2A PWWP domain containing 2A -1.97694
ZNF44 zinc finger protein 44 -1.97221
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -1.96303
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -1.95353
EIF3G eukaryotic translation initiation factor 3, subunit G -1.94685
ZNF136 zinc finger protein 136 -1.94548
NAP1L4 nucleosome assembly protein 1-like 4 -1.94536
ZNF443 zinc finger protein 443 -1.93972
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -1.93382
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.93075
FABP7 fatty acid binding protein 7, brain -1.91868
CEP63 centrosomal protein 63kDa -1.91026
ULBP1 UL16 binding protein 1 -1.87062
SPDEF SAM pointed domain containing ETS transcription factor -1.86869
ANAPC13 anaphase promoting complex subunit 13 -1.86685
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -1.85595
PFKL phosphofructokinase, liver -1.8499
ZNF551 zinc finger protein 551 -1.8469
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.81371
FBXL12 F-box and leucine-rich repeat protein 12 -1.80305
MRPL23 mitochondrial ribosomal protein L23 -1.79705
IGHD immunoglobulin heavy constant delta -1.78937
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -1.7837
DPF2 D4, zinc and double PHD fingers family 2 -1.77686
HMGN5 high mobility group nucleosome binding domain 5 -1.77539
WDR74 WD repeat domain 74 -1.76634
MPC1 mitochondrial pyruvate carrier 1 -1.75821
POFUT2 protein O-fucosyltransferase 2 -1.75616
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -1.75471
WSB1 WD repeat and SOCS box containing 1 -1.75288
FHIT fragile histidine triad -1.74175
OMD osteomodulin -1.74029
DGKE diacylglycerol kinase, epsilon 64kDa -1.73965
HIST3H2A histone cluster 3, H2a -1.73566
GTPBP6 GTP binding protein 6 (putative) -1.73441
TBC1D5 TBC1 domain family, member 5 -1.73181
TERF2IP telomeric repeat binding factor 2, interacting protein -1.70642
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.68714
CA5BP1 carbonic anhydrase VB pseudogene 1 -1.6829
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -1.67528
TXNL4A thioredoxin-like 4A -1.67507
KLF3 Kruppel-like factor 3 (basic) -1.66949
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -1.66808
ZNF549 zinc finger protein 549 -1.6631
NARS asparaginyl-tRNA synthetase -1.65642
RAB4A RAB4A, member RAS oncogene family -1.65588
MED24 mediator complex subunit 24 -1.64415
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.63484
MMP10 matrix metallopeptidase 10 -1.62157
FBXW4 F-box and WD repeat domain containing 4 -1.61655
PDCD2 programmed cell death 2 -1.6139
IMPG2 interphotoreceptor matrix proteoglycan 2 -1.60561
DDB1 damage-specific DNA binding protein 1, 127kDa -1.59711
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -1.59695
ZNF20 zinc finger protein 20 -1.59635
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -1.5936
MTDH metadherin -1.58858
SLC2A3P1 solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 -1.58236
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -1.57243
FNTA farnesyltransferase, CAAX box, alpha -1.56958
TBL1X transducin (beta)-like 1X-linked -1.55461
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -1.54651
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -1.54436
MTMR9 myotubularin related protein 9 -1.53892
NAG18 NAG18 mRNA -1.53514
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -1.52724
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -1.51531
MAP6D1 MAP6 domain containing 1 -1.5136
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -1.49975
RNH1 ribonuclease/angiogenin inhibitor 1 -1.49968
CRBN cereblon -1.49959
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -1.49913
MAN2C1 mannosidase, alpha, class 2C, member 1 -1.49615
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding) -1.49298
ZNF343 zinc finger protein 343 -1.48435
LRP4 low density lipoprotein receptor-related protein 4 -1.47448
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -1.46569
THAP1 THAP domain containing, apoptosis associated protein 1 -1.46404
NUP98 nucleoporin 98kDa -1.45388
XPA xeroderma pigmentosum, complementation group A -1.45376
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic -1.45026
NRG2 neuregulin 2 -1.44942
YARS tyrosyl-tRNA synthetase -1.44082
GPR157 G protein-coupled receptor 157 -1.44027
ODC1 ornithine decarboxylase 1 -1.43994
COX7C cytochrome c oxidase subunit VIIc -1.42804
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -1.42608
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -1.4233
PTGDR2 prostaglandin D2 receptor 2 -1.42107
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.42079
EML3 echinoderm microtubule associated protein like 3 -1.4178
GRIK1 glutamate receptor, ionotropic, kainate 1 -1.41763