TE-15 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human esophageal squamous cell carcinoma cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004598)
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Genes

341 genes with high or low expression in TE-15 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
UVRAG UV radiation resistance associated 3.59734
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 3.5899
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 3.06965
GLUD2 glutamate dehydrogenase 2 2.8419
HACD2 3-hydroxyacyl-CoA dehydratase 2 2.83184
TOM1L2 target of myb1-like 2 (chicken) 2.82165
DLK2 delta-like 2 homolog (Drosophila) 2.67971
ZNF133 zinc finger protein 133 2.66174
RAB40B RAB40B, member RAS oncogene family 2.58425
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.51056
ALS2CL ALS2 C-terminal like 2.50832
GLUD1 glutamate dehydrogenase 1 2.48722
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 2.47572
MMP12 matrix metallopeptidase 12 2.46825
FMO3 flavin containing monooxygenase 3 2.44512
DUSP10 dual specificity phosphatase 10 2.37069
SLC39A2 solute carrier family 39 (zinc transporter), member 2 2.3683
PLCE1 phospholipase C, epsilon 1 2.3148
KRT4 keratin 4, type II 2.30558
CEP70 centrosomal protein 70kDa 2.30545
BCO1 beta-carotene oxygenase 1 2.28559
PAX9 paired box 9 2.28107
UPK1B uroplakin 1B 2.21528
WISP3 WNT1 inducible signaling pathway protein 3 2.20579
MUC16 mucin 16, cell surface associated 2.1857
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 2.17515
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.13412
FOLR1 folate receptor 1 (adult) 2.13209
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 2.11747
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.10572
CALML5 calmodulin-like 5 2.09879
FOXE1 forkhead box E1 2.09263
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.08002
KLHDC2 kelch domain containing 2 2.06073
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 2.0542
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 2.02867
LY6D lymphocyte antigen 6 complex, locus D 2.02569
TNNI2 troponin I type 2 (skeletal, fast) 2.02172
LMO7 LIM domain 7 2.01873
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 1.99185
EDAR ectodysplasin A receptor 1.98965
A4GALT alpha 1,4-galactosyltransferase 1.98639
SECTM1 secreted and transmembrane 1 1.98638
TRAFD1 TRAF-type zinc finger domain containing 1 1.97711
HCAR3 hydroxycarboxylic acid receptor 3 1.97471
FYB FYN binding protein 1.97108
LYPD1 LY6/PLAUR domain containing 1 1.96631
CLCA4 chloride channel accessory 4 1.9637
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 1.94986
RNF17 ring finger protein 17 1.94906
MMP10 matrix metallopeptidase 10 1.94566
USP25 ubiquitin specific peptidase 25 1.94265
FN3KRP fructosamine 3 kinase related protein 1.93269
LOC57399 uncharacterized gastric protein ZA52P 1.928
DIAPH2-AS1 DIAPH2 antisense RNA 1 1.90489
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.90385
PADI3 peptidyl arginine deiminase, type III 1.89886
DSC3 desmocollin 3 1.88982
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 1.88775
VWF von Willebrand factor 1.88758
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 1.88678
FAM168A family with sequence similarity 168, member A 1.8857
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.87742
MAPK10 mitogen-activated protein kinase 10 1.87086
FMR1 fragile X mental retardation 1 1.8575
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 1.85171
BCAS1 breast carcinoma amplified sequence 1 1.84343
PDZK1 PDZ domain containing 1 1.84341
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.83707
PER3 period circadian clock 3 1.82936
VILL villin-like 1.82705
CALML3 calmodulin-like 3 1.82308
PSCA prostate stem cell antigen 1.81204
PHEX phosphate regulating endopeptidase homolog, X-linked 1.81178
GRAMD1C GRAM domain containing 1C 1.80845
MNAT1 MNAT CDK-activating kinase assembly factor 1 1.79955
VSNL1 visinin-like 1 1.79449
DKK4 dickkopf WNT signaling pathway inhibitor 4 1.79385
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 1.78732
COL17A1 collagen, type XVII, alpha 1 1.78433
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 1.77098
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.77008
CTSV cathepsin V 1.76198
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.75977
CAPN5 calpain 5 1.74538
GJB5 gap junction protein, beta 5, 31.1kDa 1.74024
LGALS7 lectin, galactoside-binding, soluble, 7 1.73113
CLDN8 claudin 8 1.7254
CHMP3 charged multivesicular body protein 3 1.72142
ALCAM activated leukocyte cell adhesion molecule 1.72042
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 1.71125
IL1RN interleukin 1 receptor antagonist 1.70877
GIPC2 GIPC PDZ domain containing family, member 2 1.70198
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 1.694
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 1.68924
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 1.68753
ARTN artemin 1.687
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.68591
DPYD dihydropyrimidine dehydrogenase 1.68365
IGBP1 immunoglobulin (CD79A) binding protein 1 1.68249
OSBPL9 oxysterol binding protein-like 9 1.67362
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.67134
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 1.66927
KRT13 keratin 13, type I 1.66776
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.65034
RSF1 remodeling and spacing factor 1 1.64753
SCEL sciellin 1.64458
APOL1 apolipoprotein L, 1 1.63988
DUOX1 dual oxidase 1 1.63986
EGFL6 EGF-like-domain, multiple 6 1.63877
DAAM1 dishevelled associated activator of morphogenesis 1 1.6362
MED6 mediator complex subunit 6 1.62104
PLXNB1 plexin B1 1.61897
METAP1 methionyl aminopeptidase 1 1.6145
TRIP11 thyroid hormone receptor interactor 11 1.61349
STK38 serine/threonine kinase 38 1.60569
LPCAT4 lysophosphatidylcholine acyltransferase 4 1.60252
NADSYN1 NAD synthetase 1 1.58861
DOCK1 dedicator of cytokinesis 1 1.58847
EMILIN2 elastin microfibril interfacer 2 1.58598
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 1.57575
TMLHE trimethyllysine hydroxylase, epsilon 1.56483
CALB1 calbindin 1, 28kDa 1.56476
LHX6 LIM homeobox 6 1.56239
TTC9 tetratricopeptide repeat domain 9 1.55639
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 1.5557
KLHL2 kelch-like family member 2 1.54983
KIF13A kinesin family member 13A 1.54716
TGM1 transglutaminase 1 1.5363
RIT2 Ras-like without CAAX 2 1.53555
DSG3 desmoglein 3 1.53518
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.53417
PCDH7 protocadherin 7 1.53296
SMC6 structural maintenance of chromosomes 6 1.53089
TSPAN1 tetraspanin 1 1.51845
DCAF8 DDB1 and CUL4 associated factor 8 1.51758
PARP2 poly (ADP-ribose) polymerase 2 1.51443
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.51385
PERP PERP, TP53 apoptosis effector 1.51385
KLK7 kallikrein-related peptidase 7 1.51017
HCRP1 hepatocellular carcinoma-related HCRP1 1.50792
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 1.50602
SPATA7 spermatogenesis associated 7 1.50517
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 1.50457
FGFR2 fibroblast growth factor receptor 2 1.50092
SAP30BP SAP30 binding protein 1.48863
CCDC53 coiled-coil domain containing 53 1.48765
HPSE heparanase 1.48668
NMU neuromedin U 1.4862
OSTF1 osteoclast stimulating factor 1 1.47678
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.47602
FGFR3 fibroblast growth factor receptor 3 1.47336
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.4623
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 1.46221
TCN2 transcobalamin II 1.45774
BLCAP bladder cancer associated protein 1.45418
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 1.45297
ZBTB5 zinc finger and BTB domain containing 5 1.45198
SOX15 SRY (sex determining region Y)-box 15 1.45052
TSPAN6 tetraspanin 6 1.44931
CLCA2 chloride channel accessory 2 1.44114
CKM creatine kinase, muscle 1.43849
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 1.43845
IFT38 intraflagellar transport 38 1.4341
SH3YL1 SH3 and SYLF domain containing 1 1.4328
THRB thyroid hormone receptor, beta 1.43043
ADAMTSL3 ADAMTS-like 3 1.42969
TM9SF2 transmembrane 9 superfamily member 2 1.42783
GJB3 gap junction protein, beta 3, 31kDa 1.42685
TSKU tsukushi, small leucine rich proteoglycan 1.42224
BHLHE41 basic helix-loop-helix family, member e41 1.42008
FOS FBJ murine osteosarcoma viral oncogene homolog 1.4188
GMPR2 guanosine monophosphate reductase 2 1.41843
DHRS1 dehydrogenase/reductase (SDR family) member 1 1.41842
RIPK4 receptor-interacting serine-threonine kinase 4 1.41842
PLA2G10 phospholipase A2, group X 1.41727

low expression

Symbol Name Standardized Value
ZNF696 zinc finger protein 696 -3.33293
PPIF peptidylprolyl isomerase F -3.32302
PTCD1 pentatricopeptide repeat domain 1 -3.0915
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -3.02601
BUD31 BUD31 homolog (S. cerevisiae) -2.77554
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -2.75489
ELK1 ELK1, member of ETS oncogene family -2.7335
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -2.66748
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.62796
RRP1 ribosomal RNA processing 1 -2.60106
PUS7 pseudouridylate synthase 7 (putative) -2.52977
COPS6 COP9 signalosome subunit 6 -2.49853
AGO2 argonaute RISC catalytic component 2 -2.41152
QTRT1 queuine tRNA-ribosyltransferase 1 -2.38437
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -2.36974
MTCH2 mitochondrial carrier 2 -2.31386
RBM28 RNA binding motif protein 28 -2.31177
SPAG6 sperm associated antigen 6 -2.3099
MAP2K6 mitogen-activated protein kinase kinase 6 -2.28825
EXOSC4 exosome component 4 -2.26748
MPST mercaptopyruvate sulfurtransferase -2.26626
FANCF Fanconi anemia, complementation group F -2.26409
HSPA8 heat shock 70kDa protein 8 -2.24519
KCTD13 potassium channel tetramerization domain containing 13 -2.15977
GRWD1 glutamate-rich WD repeat containing 1 -2.14157
SCRIB scribbled planar cell polarity protein -2.11886
TGS1 trimethylguanosine synthase 1 -2.1134
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.09329
LRRTM2 leucine rich repeat transmembrane neuronal 2 -2.09284
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.08279
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.07191
MEPCE methylphosphate capping enzyme -2.06436
RABEPK Rab9 effector protein with kelch motifs -2.06084
LARP1 La ribonucleoprotein domain family, member 1 -2.05051
BANP BTG3 associated nuclear protein -2.04605
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.04432
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -2.03993
NAV1 neuron navigator 1 -2.03227
TRIM37 tripartite motif containing 37 -2.02068
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -2.01108
CD3EAP CD3e molecule, epsilon associated protein -1.99971
MARS methionyl-tRNA synthetase -1.99739
CYC1 cytochrome c-1 -1.99465
ITGAV integrin, alpha V -1.96896
PCYOX1L prenylcysteine oxidase 1 like -1.95868
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -1.94472
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -1.94382
ASNSD1 asparagine synthetase domain containing 1 -1.9395
ACAT1 acetyl-CoA acetyltransferase 1 -1.93562
NT5M 5',3'-nucleotidase, mitochondrial -1.93543
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -1.93452
CCDC86 coiled-coil domain containing 86 -1.9191
TST thiosulfate sulfurtransferase (rhodanese) -1.86282
SDCCAG3 serologically defined colon cancer antigen 3 -1.85771
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -1.85094
CORO2B coronin, actin binding protein, 2B -1.83229
HSPD1 heat shock 60kDa protein 1 (chaperonin) -1.82357
TIAM2 T-cell lymphoma invasion and metastasis 2 -1.81882
CCDC106 coiled-coil domain containing 106 -1.81658
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -1.81343
LRP3 low density lipoprotein receptor-related protein 3 -1.80887
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -1.80675
ACLY ATP citrate lyase -1.80468
SRM spermidine synthase -1.80106
PTDSS2 phosphatidylserine synthase 2 -1.80003
IFT54 intraflagellar transport 54 -1.79993
XAB2 XPA binding protein 2 -1.78482
MCOLN1 mucolipin 1 -1.7751
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.77445
PLXNC1 plexin C1 -1.76839
KLHL18 kelch-like family member 18 -1.76605
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -1.7647
RNPS1 RNA binding protein S1, serine-rich domain -1.76316
TMEM147 transmembrane protein 147 -1.75673
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 -1.74496
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -1.72615
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -1.72578
RIMS2 regulating synaptic membrane exocytosis 2 -1.72463
HSPA9 heat shock 70kDa protein 9 (mortalin) -1.72377
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -1.71356
ORC5 origin recognition complex, subunit 5 -1.71292
KLHL29 kelch-like family member 29 -1.70824
PDGFRL platelet-derived growth factor receptor-like -1.70595
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.7059
GARS glycyl-tRNA synthetase -1.70358
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -1.69028
BTNL3 butyrophilin-like 3 -1.6824
RUVBL2 RuvB-like AAA ATPase 2 -1.6663
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.66146
NUPL1 nucleoporin like 1 -1.65268
PFDN2 prefoldin subunit 2 -1.6399
ZC3H15 zinc finger CCCH-type containing 15 -1.63367
FAM13C family with sequence similarity 13, member C -1.63027
WDR62 WD repeat domain 62 -1.62694
CDC34 cell division cycle 34 -1.61647
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -1.61643
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -1.61336
PPAT phosphoribosyl pyrophosphate amidotransferase -1.61073
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -1.61057
TAS2R1 taste receptor, type 2, member 1 -1.61048
NFYA nuclear transcription factor Y, alpha -1.60549
SNED1 sushi, nidogen and EGF-like domains 1 -1.60122
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 -1.59859
SLC2A3P1 solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1 -1.59492
MRPL9 mitochondrial ribosomal protein L9 -1.58977
IFT27 intraflagellar transport 27 -1.5828
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -1.58192
NHEJ1 nonhomologous end-joining factor 1 -1.58047
POU6F1 POU class 6 homeobox 1 -1.57458
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 -1.57357
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.56903
KRT32 keratin 32, type I -1.56739
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -1.56394
PPP1R9A protein phosphatase 1, regulatory subunit 9A -1.56184
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -1.56053
CSHL1 chorionic somatomammotropin hormone-like 1 -1.55958
SLC16A6 solute carrier family 16, member 6 -1.55256
ZPR1 ZPR1 zinc finger -1.55017
TSTA3 tissue specific transplantation antigen P35B -1.54783
ZBTB40 zinc finger and BTB domain containing 40 -1.54722
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -1.5464
TUBB2B tubulin, beta 2B class IIb -1.54006
JPH3 junctophilin 3 -1.53898
DCTPP1 dCTP pyrophosphatase 1 -1.53842
POFUT2 protein O-fucosyltransferase 2 -1.53777
RUNX3 runt-related transcription factor 3 -1.53718
RHOBTB1 Rho-related BTB domain containing 1 -1.53625
TOR1B torsin family 1, member B (torsin B) -1.53557
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -1.51997
SQLE squalene epoxidase -1.51908
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -1.51884
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -1.50594
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -1.50093
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.50006
EXOSC5 exosome component 5 -1.49849
NOL11 nucleolar protein 11 -1.49734
FKBP4 FK506 binding protein 4, 59kDa -1.4969
FAM53C family with sequence similarity 53, member C -1.4891
HYPK huntingtin interacting protein K -1.48804
NUDC nudC nuclear distribution protein -1.48532
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -1.47379
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.46624
TMEM176A transmembrane protein 176A -1.46559
RTN1 reticulon 1 -1.46375
RAB8B RAB8B, member RAS oncogene family -1.46264
EIF3B eukaryotic translation initiation factor 3, subunit B -1.45662
SRP19 signal recognition particle 19kDa -1.45631
PRKACB protein kinase, cAMP-dependent, catalytic, beta -1.45494
HSPE1 heat shock 10kDa protein 1 -1.45011
XPOT exportin, tRNA -1.44784
AP4M1 adaptor-related protein complex 4, mu 1 subunit -1.44782
IQSEC1 IQ motif and Sec7 domain 1 -1.44514
RPA4 replication protein A4, 30kDa -1.4435
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 -1.44169
ASNS asparagine synthetase (glutamine-hydrolyzing) -1.43906
PAK1IP1 PAK1 interacting protein 1 -1.43889
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -1.4358
PTRH2 peptidyl-tRNA hydrolase 2 -1.43239
ACAA2 acetyl-CoA acyltransferase 2 -1.43198
ETV2 ets variant 2 -1.42704
NSD1 nuclear receptor binding SET domain protein 1 -1.42489
MAPK12 mitogen-activated protein kinase 12 -1.4236
PPID peptidylprolyl isomerase D -1.42338
CPLX2 complexin 2 -1.41888
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -1.4156