TE-5 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from poorly differntiated esophageal squamous cell carcinoma. Not transplantable to nude mouse. TKG0256 (Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051375)
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Genes

329 genes with high or low expression in TE-5 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
ODF1 outer dense fiber of sperm tails 1 3.60177
TP53TG1 TP53 target 1 (non-protein coding) 3.60177
KLHDC2 kelch domain containing 2 3.23788
STK19 serine/threonine kinase 19 3.17571
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 3.09884
STX5 syntaxin 5 3.07379
GOLGA1 golgin A1 2.92206
TMX2 thioredoxin-related transmembrane protein 2 2.76165
EXD2 exonuclease 3'-5' domain containing 2 2.64752
NEK9 NIMA-related kinase 9 2.63974
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.619
ZFPL1 zinc finger protein-like 1 2.59286
OSBP oxysterol binding protein 2.5666
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.55329
NEK11 NIMA-related kinase 11 2.52104
AKTIP AKT interacting protein 2.51886
CTNND1 catenin (cadherin-associated protein), delta 1 2.49388
INPP1 inositol polyphosphate-1-phosphatase 2.47693
RNF13 ring finger protein 13 2.46759
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.46047
H2AFJ H2A histone family, member J 2.44806
MRPL49 mitochondrial ribosomal protein L49 2.4279
SEC23IP SEC23 interacting protein 2.40928
RBM4B RNA binding motif protein 4B 2.34814
CROT carnitine O-octanoyltransferase 2.32846
CEP63 centrosomal protein 63kDa 2.30689
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 2.30301
DDB1 damage-specific DNA binding protein 1, 127kDa 2.3018
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.30089
GPR107 G protein-coupled receptor 107 2.2994
KRIT1 KRIT1, ankyrin repeat containing 2.2901
COQ9 coenzyme Q9 2.25202
SRP54 signal recognition particle 54kDa 2.24693
DMTF1 cyclin D binding myb-like transcription factor 1 2.19907
FAM179B family with sequence similarity 179, member B 2.19115
AKAP9 A kinase (PRKA) anchor protein 9 2.18871
SLC39A7 solute carrier family 39 (zinc transporter), member 7 2.18805
FAF2 Fas associated factor family member 2 2.18518
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.15973
CEP70 centrosomal protein 70kDa 2.1548
FBXO34 F-box protein 34 2.1489
GATAD1 GATA zinc finger domain containing 1 2.11236
ZBTB3 zinc finger and BTB domain containing 3 2.09845
STYXL1 serine/threonine/tyrosine interacting-like 1 2.09307
RC3H2 ring finger and CCCH-type domains 2 2.08394
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.08327
BLCAP bladder cancer associated protein 2.07371
ACBD3 acyl-CoA binding domain containing 3 2.07176
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 2.05722
DVL3 dishevelled segment polarity protein 3 2.04833
SDHAF3 succinate dehydrogenase complex assembly factor 3 2.04718
MPPED2 metallophosphoesterase domain containing 2 2.04141
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.03516
SGCE sarcoglycan, epsilon 2.02251
MRPS22 mitochondrial ribosomal protein S22 2.01503
CREB3 cAMP responsive element binding protein 3 2.01023
PHTF2 putative homeodomain transcription factor 2 2.00621
WBP5 WW domain binding protein 5 2.00438
HCG4 HLA complex group 4 (non-protein coding) 1.99263
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.99233
EYA2 EYA transcriptional coactivator and phosphatase 2 1.98928
WDR5B WD repeat domain 5B 1.96946
STK38 serine/threonine kinase 38 1.9435
PHKB phosphorylase kinase, beta 1.92951
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 1.88879
CNOT1 CCR4-NOT transcription complex, subunit 1 1.87877
ZNF204P zinc finger protein 204, pseudogene 1.87447
FBXW11 F-box and WD repeat domain containing 11 1.85626
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 1.8405
MON1B MON1 secretory trafficking family member B 1.82717
NUP133 nucleoporin 133kDa 1.81171
ZDHHC7 zinc finger, DHHC-type containing 7 1.80954
ALPL alkaline phosphatase, liver/bone/kidney 1.78683
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 1.76306
SYNE2 spectrin repeat containing, nuclear envelope 2 1.76303
GOLGA5 golgin A5 1.76007
NKX2-5 NK2 homeobox 5 1.75506
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.73984
MMP13 matrix metallopeptidase 13 1.73906
SRI sorcin 1.73262
SIAH2 siah E3 ubiquitin protein ligase 2 1.72659
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 1.72079
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 1.7196
GANAB glucosidase, alpha; neutral AB 1.71848
RBM23 RNA binding motif protein 23 1.71779
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 1.70646
GOLGA3 golgin A3 1.70341
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 1.70188
FMO6P flavin containing monooxygenase 6 pseudogene 1.7013
SEC16A SEC16 homolog A (S. cerevisiae) 1.69683
RNF7 ring finger protein 7 1.69676
ARMC8 armadillo repeat containing 8 1.6949
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.69334
MYOT myotilin 1.69149
MMP12 matrix metallopeptidase 12 1.6809
CAPN1 calpain 1, (mu/I) large subunit 1.6747
PEX6 peroxisomal biogenesis factor 6 1.67463
TRIP11 thyroid hormone receptor interactor 11 1.67201
WDR45B WD repeat domain 45B 1.65646
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 1.65185
CLDN1 claudin 1 1.64923
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.64823
MTERF1 mitochondrial transcription termination factor 1 1.64381
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.64071
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.63321
BET1 Bet1 golgi vesicular membrane trafficking protein 1.61468
GMPR2 guanosine monophosphate reductase 2 1.6145
CELP carboxyl ester lipase pseudogene 1.61211
DUOX2 dual oxidase 2 1.60923
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.60359
MGC4859 uncharacterized LOC79150 1.60153
RBBP7 retinoblastoma binding protein 7 1.59643
SEC23A Sec23 homolog A (S. cerevisiae) 1.59428
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.59127
ACOT9 acyl-CoA thioesterase 9 1.58935
PLCE1 phospholipase C, epsilon 1 1.58785
FOS FBJ murine osteosarcoma viral oncogene homolog 1.58313
OSBPL2 oxysterol binding protein-like 2 1.58283
AARS alanyl-tRNA synthetase 1.58141
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.57475
KAT5 K(lysine) acetyltransferase 5 1.57312
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.57253
TRAFD1 TRAF-type zinc finger domain containing 1 1.57003
SPAG16 sperm associated antigen 16 1.56995
STAG1 stromal antigen 1 1.5644
TMEM40 transmembrane protein 40 1.56435
HCAR3 hydroxycarboxylic acid receptor 3 1.56359
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 1.56235
PPP1R3D protein phosphatase 1, regulatory subunit 3D 1.54163
RAB40C RAB40C, member RAS oncogene family 1.54159
CCIN calicin 1.54043
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.54034
KRT10 keratin 10, type I 1.53588
ARF1 ADP-ribosylation factor 1 1.53478
GOLGB1 golgin B1 1.53066
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.52937
CEL carboxyl ester lipase 1.52542
TLDC1 TBC/LysM-associated domain containing 1 1.52175
GAPVD1 GTPase activating protein and VPS9 domains 1 1.52132
MLYCD malonyl-CoA decarboxylase 1.5171
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.5133
MEN1 multiple endocrine neoplasia I 1.51249
CP ceruloplasmin (ferroxidase) 1.51177
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 1.51016
LMAN2L lectin, mannose-binding 2-like 1.50985
CNTN1 contactin 1 1.50827
FOXL2 forkhead box L2 1.50075
COPG1 coatomer protein complex, subunit gamma 1 1.49957
LHX3 LIM homeobox 3 1.49677
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.48802
EML3 echinoderm microtubule associated protein like 3 1.48356
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 1.48257
RPL36AL ribosomal protein L36a-like 1.47703
TTLL5 tubulin tyrosine ligase-like family member 5 1.47359
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.47016
HS1BP3 HCLS1 binding protein 3 1.46862
TNNI2 troponin I type 2 (skeletal, fast) 1.4661
SUSD6 sushi domain containing 6 1.45882
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.45726
ARF4 ADP-ribosylation factor 4 1.45364
DAP death-associated protein 1.45238
TM9SF1 transmembrane 9 superfamily member 1 1.44928
TLR5 toll-like receptor 5 1.448
TKFC triokinase/FMN cyclase 1.4464
DOLPP1 dolichyldiphosphatase 1 1.43148
PLD1 phospholipase D1, phosphatidylcholine-specific 1.42801
FADS1 fatty acid desaturase 1 1.42544
PARL presenilin associated, rhomboid-like 1.41877
TTC13 tetratricopeptide repeat domain 13 1.41762
PSEN1 presenilin 1 1.41751

low expression

Symbol Name Standardized Value
RBM28 RNA binding motif protein 28 -3.53725
ATP11A ATPase, class VI, type 11A -3.53725
SMYD3 SET and MYND domain containing 3 -3.53694
GPX4 glutathione peroxidase 4 -3.53097
ING3 inhibitor of growth family, member 3 -3.09729
ZBED4 zinc finger, BED-type containing 4 -2.99982
RPP30 ribonuclease P/MRP 30kDa subunit -2.87167
CSNK1E casein kinase 1, epsilon -2.70169
WASL Wiskott-Aldrich syndrome-like -2.63418
ATG12 autophagy related 12 -2.54195
EXOSC5 exosome component 5 -2.5186
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.5002
DDT D-dopachrome tautomerase -2.45417
RABIF RAB interacting factor -2.40049
CRELD2 cysteine-rich with EGF-like domains 2 -2.38985
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -2.36513
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.31617
SRP19 signal recognition particle 19kDa -2.26271
FBL fibrillarin -2.24335
XYLB xylulokinase homolog (H. influenzae) -2.22878
NUP205 nucleoporin 205kDa -2.22732
MXI1 MAX interactor 1, dimerization protein -2.21054
IFT54 intraflagellar transport 54 -2.1991
YTHDC2 YTH domain containing 2 -2.17979
KIAA0754 KIAA0754 -2.17369
NUPL1 nucleoporin like 1 -2.17075
CNOT4 CCR4-NOT transcription complex, subunit 4 -2.14595
RPL10L ribosomal protein L10-like -2.13627
RIF1 replication timing regulatory factor 1 -2.11952
TWF2 twinfilin actin binding protein 2 -2.11405
DAP3 death associated protein 3 -2.10058
ZNF696 zinc finger protein 696 -2.08366
IRF7 interferon regulatory factor 7 -2.06886
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) -2.06468
SNRPF small nuclear ribonucleoprotein polypeptide F -2.04768
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -2.03871
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.00661
E2F6 E2F transcription factor 6 -2.00285
EXOG endo/exonuclease (5'-3'), endonuclease G-like -1.9885
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -1.98576
NOL10 nucleolar protein 10 -1.95263
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -1.91448
HAMP hepcidin antimicrobial peptide -1.90451
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -1.89314
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -1.88976
EIF5A eukaryotic translation initiation factor 5A -1.88123
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -1.85951
INTS1 integrator complex subunit 1 -1.84315
PUS3 pseudouridylate synthase 3 -1.84167
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -1.84098
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -1.83587
NCOA2 nuclear receptor coactivator 2 -1.83586
TNPO3 transportin 3 -1.83507
KRT24 keratin 24, type I -1.8267
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -1.81932
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -1.80944
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.80658
NOP56 NOP56 ribonucleoprotein -1.80004
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 -1.79201
PRAF2 PRA1 domain family, member 2 -1.78479
NONO non-POU domain containing, octamer-binding -1.76843
THAP3 THAP domain containing, apoptosis associated protein 3 -1.75466
TBP TATA box binding protein -1.74751
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.74601
TIPIN TIMELESS interacting protein -1.74373
MAGEA11 melanoma antigen family A11 -1.74312
SBF1 SET binding factor 1 -1.74309
GRWD1 glutamate-rich WD repeat containing 1 -1.73839
POMT1 protein-O-mannosyltransferase 1 -1.73649
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -1.73018
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -1.72649
WDR45 WD repeat domain 45 -1.71628
OTUD3 OTU deubiquitinase 3 -1.71151
PYY peptide YY -1.7027
TBCA tubulin folding cofactor A -1.70088
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -1.69259
ZFP69B ZFP69 zinc finger protein B -1.68205
RAD17 RAD17 homolog (S. pombe) -1.67477
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.67443
BMX BMX non-receptor tyrosine kinase -1.6733
NLGN1 neuroligin 1 -1.66951
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) -1.66852
FLCN folliculin -1.65691
BYSL bystin-like -1.65491
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -1.64767
PKNOX1 PBX/knotted 1 homeobox 1 -1.64285
NLGN4Y neuroligin 4, Y-linked -1.63315
TM2D1 TM2 domain containing 1 -1.63255
LRRC40 leucine rich repeat containing 40 -1.63038
GPR75 G protein-coupled receptor 75 -1.62998
ANK2 ankyrin 2, neuronal -1.62633
ZNF451 zinc finger protein 451 -1.61952
CTPS1 CTP synthase 1 -1.61887
DLL3 delta-like 3 (Drosophila) -1.61196
KIAA0020 KIAA0020 -1.60179
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.59287
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -1.58998
SLITRK3 SLIT and NTRK-like family, member 3 -1.58427
ENO2 enolase 2 (gamma, neuronal) -1.5831
MAPK8 mitogen-activated protein kinase 8 -1.58303
EPHA3 EPH receptor A3 -1.58233
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -1.57081
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.57072
RPL23AP7 ribosomal protein L23a pseudogene 7 -1.56663
MTCH2 mitochondrial carrier 2 -1.56257
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 -1.5624
PTGDR2 prostaglandin D2 receptor 2 -1.55983
GAB2 GRB2-associated binding protein 2 -1.55148
IL5RA interleukin 5 receptor, alpha -1.54971
SCO2 SCO2 cytochrome c oxidase assembly protein -1.54485
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -1.54181
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -1.54177
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -1.53905
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 -1.53009
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -1.52922
MMP2 matrix metallopeptidase 2 -1.52893
G6PC3 glucose 6 phosphatase, catalytic, 3 -1.52752
ACP1 acid phosphatase 1, soluble -1.52746
IQCH IQ motif containing H -1.52724
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 -1.52457
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 -1.51945
ZMYM5 zinc finger, MYM-type 5 -1.51144
ART1 ADP-ribosyltransferase 1 -1.51067
MAT2A methionine adenosyltransferase II, alpha -1.50582
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.50015
AZI2 5-azacytidine induced 2 -1.49992
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -1.49289
CHD1 chromodomain helicase DNA binding protein 1 -1.49129
ABHD14A abhydrolase domain containing 14A -1.48993
TMEM147 transmembrane protein 147 -1.47917
C1QBP complement component 1, q subcomponent binding protein -1.47467
ERF Ets2 repressor factor -1.47319
GSTT1 glutathione S-transferase theta 1 -1.47302
PRPF31 pre-mRNA processing factor 31 -1.47219
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -1.46661
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -1.46309
PFDN2 prefoldin subunit 2 -1.46028
NME1 NME/NM23 nucleoside diphosphate kinase 1 -1.45987
ACAA2 acetyl-CoA acyltransferase 2 -1.45788
NGLY1 N-glycanase 1 -1.45549
HHCM Mahlavu hepatocellular carcinoma -1.45027
TECTA tectorin alpha -1.44975
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -1.44423
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -1.44298
ZNF571 zinc finger protein 571 -1.44007
ZNF222 zinc finger protein 222 -1.4395
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -1.43903
GRM2 glutamate receptor, metabotropic 2 -1.43349
CD79B CD79b molecule, immunoglobulin-associated beta -1.43345
CAPN5 calpain 5 -1.43232
SERHL serine hydrolase-like (pseudogene) -1.43045
TSSC1 tumor suppressing subtransferable candidate 1 -1.43021
LIN7B lin-7 homolog B (C. elegans) -1.42352
RPAP1 RNA polymerase II associated protein 1 -1.42295
PMP2 peripheral myelin protein 2 -1.42126
SH3YL1 SH3 and SYLF domain containing 1 -1.41982
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -1.41955
KIF3A kinesin family member 3A -1.41755
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -1.41687