TE-6 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description A immortal human esophagus-derived cell line cell that has the characteristics: Highly differentiated squamous carcinoma (esophagus), not transplantable to nude mouse. 　A culture submitted to the Cell Resource Center for Biomedical Research was found to be contaminated with mycoplasma. Progeny were cured by Treatments with BM Cyclin and MC210. TKG0257 (Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051376)
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Genes

279 genes with high or low expression in TE-6 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
EDC3 enhancer of mRNA decapping 3 3.60177
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.59661
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 3.58705
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 3.58052
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.22076
CAND1 cullin-associated and neddylation-dissociated 1 3.0032
GMPR2 guanosine monophosphate reductase 2 2.94728
FADD Fas (TNFRSF6)-associated via death domain 2.6741
SUSD4 sushi domain containing 4 2.63733
AQP4 aquaporin 4 2.56585
YEATS4 YEATS domain containing 4 2.54845
GSTA1 glutathione S-transferase alpha 1 2.54267
OXA1L oxidase (cytochrome c) assembly 1-like 2.5147
IMP3 IMP3, U3 small nucleolar ribonucleoprotein 2.51339
SRSF5 serine/arginine-rich splicing factor 5 2.48504
KRT10 keratin 10, type I 2.45606
CDK12 cyclin-dependent kinase 12 2.45028
PGD phosphogluconate dehydrogenase 2.43391
GSTM1 glutathione S-transferase mu 1 2.41405
ARTN artemin 2.3942
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.38637
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 2.36813
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.35863
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.29931
FBXO34 F-box protein 34 2.25405
SIAH2 siah E3 ubiquitin protein ligase 2 2.23966
DSC3 desmocollin 3 2.21641
MED1 mediator complex subunit 1 2.21629
GSTM2 glutathione S-transferase mu 2 (muscle) 2.21282
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.20195
JADE2 jade family PHD finger 2 2.19557
CCT2 chaperonin containing TCP1, subunit 2 (beta) 2.1928
BLMH bleomycin hydrolase 2.19107
MPI mannose phosphate isomerase 2.17847
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.16325
NUP107 nucleoporin 107kDa 2.14122
CNOT2 CCR4-NOT transcription complex, subunit 2 2.12722
MDM1 Mdm1 nuclear protein homolog (mouse) 2.11059
RPP21 ribonuclease P/MRP 21kDa subunit 2.1033
MRPS18B mitochondrial ribosomal protein S18B 2.1027
SAGE1 sarcoma antigen 1 2.09759
GCLC glutamate-cysteine ligase, catalytic subunit 2.09637
RARB retinoic acid receptor, beta 2.09295
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.07604
FECH ferrochelatase 2.02267
MRPS28 mitochondrial ribosomal protein S28 2.01311
SPIDR scaffolding protein involved in DNA repair 1.99447
CBR1 carbonyl reductase 1 1.97104
EXD2 exonuclease 3'-5' domain containing 2 1.96781
ZNF80 zinc finger protein 80 1.9519
TLR5 toll-like receptor 5 1.94159
METAP1 methionyl aminopeptidase 1 1.93354
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.93326
RNF17 ring finger protein 17 1.9227
GNL1 guanine nucleotide binding protein-like 1 1.91862
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.91635
PELI2 pellino E3 ubiquitin protein ligase family member 2 1.9069
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.89418
ZNF302 zinc finger protein 302 1.88679
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.88046
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.87877
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.87602
PTPN9 protein tyrosine phosphatase, non-receptor type 9 1.86245
ZFYVE21 zinc finger, FYVE domain containing 21 1.85806
FGFR2 fibroblast growth factor receptor 2 1.85563
MPPED1 metallophosphoesterase domain containing 1 1.8553
RCN2 reticulocalbin 2, EF-hand calcium binding domain 1.85067
GSTA4 glutathione S-transferase alpha 4 1.85055
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.84558
FXR1 fragile X mental retardation, autosomal homolog 1 1.82809
CENPJ centromere protein J 1.8271
KRT15 keratin 15, type I 1.82139
CCNL1 cyclin L1 1.80396
RPL36AL ribosomal protein L36a-like 1.75693
FEM1B fem-1 homolog b (C. elegans) 1.73852
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.73123
SPARCL1 SPARC-like 1 (hevin) 1.72582
GPR176 G protein-coupled receptor 176 1.72527
LPAR3 lysophosphatidic acid receptor 3 1.72195
PHC3 polyhomeotic homolog 3 (Drosophila) 1.72038
CNIH1 cornichon family AMPA receptor auxiliary protein 1 1.71953
RNF7 ring finger protein 7 1.70346
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 1.70337
GSTM3 glutathione S-transferase mu 3 (brain) 1.70123
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.69368
MRPL46 mitochondrial ribosomal protein L46 1.68879
SYNE2 spectrin repeat containing, nuclear envelope 2 1.68865
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 1.68126
ZFC3H1 zinc finger, C3H1-type containing 1.66837
ARMC8 armadillo repeat containing 8 1.66807
TMEM14A transmembrane protein 14A 1.66504
PPP1R13B protein phosphatase 1, regulatory subunit 13B 1.66336
ZC3H14 zinc finger CCCH-type containing 14 1.65986
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 1.65807
SOX2 SRY (sex determining region Y)-box 2 1.65348
PDCD10 programmed cell death 10 1.6486
SLC35E3 solute carrier family 35, member E3 1.64488
UNC45A unc-45 homolog A (C. elegans) 1.64171
RAB21 RAB21, member RAS oncogene family 1.63083
PKP1 plakophilin 1 1.63064
KHNYN KH and NYN domain containing 1.61542
UBA2 ubiquitin-like modifier activating enzyme 2 1.6125
KCNK2 potassium channel, two pore domain subfamily K, member 2 1.59841
GPX2 glutathione peroxidase 2 1.58992
TBC1D19 TBC1 domain family, member 19 1.5872
TP63 tumor protein p63 1.5849
FN3K fructosamine 3 kinase 1.57842
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.57679
CLP1 cleavage and polyadenylation factor I subunit 1 1.57549
SYNJ2BP synaptojanin 2 binding protein 1.57392
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 1.5732
ZNF230 zinc finger protein 230 1.57158
TG thyroglobulin 1.56755
PSEN1 presenilin 1 1.56482
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 1.56152
MCRS1 microspherule protein 1 1.56009
GPC3 glypican 3 1.55462
GRB7 growth factor receptor-bound protein 7 1.55365
NEK9 NIMA-related kinase 9 1.55181
CHODL chondrolectin 1.54449
GAREM GRB2 associated, regulator of MAPK1 1.54035
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 1.53929
NGDN neuroguidin, EIF4E binding protein 1.52899
MNAT1 MNAT CDK-activating kinase assembly factor 1 1.5287
SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.52748
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.52492
FRS2 fibroblast growth factor receptor substrate 2 1.52411
FAM179B family with sequence similarity 179, member B 1.52406
PRKD1 protein kinase D1 1.51834
TKFC triokinase/FMN cyclase 1.51776
TOM1L2 target of myb1-like 2 (chicken) 1.51526
GOLGA8B golgin A8 family, member B 1.51472
KLHDC2 kelch domain containing 2 1.51286
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.50677
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.50642
ATG14 autophagy related 14 1.49958
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 1.4992
NTS neurotensin 1.49901
PRKX protein kinase, X-linked 1.49769
SPAST spastin 1.48909
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.48734
PRPF39 pre-mRNA processing factor 39 1.48513
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.48242
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 1.47446
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.46414
SOS1 son of sevenless homolog 1 (Drosophila) 1.46343
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 1.46171
KRT4 keratin 4, type II 1.46159
CLDND1 claudin domain containing 1 1.45914
PLD2 phospholipase D2 1.45439
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.45238
KRT13 keratin 13, type I 1.45184
CLK3 CDC-like kinase 3 1.45134
FNTB farnesyltransferase, CAAX box, beta 1.45011
SNUPN snurportin 1 1.44965
TNNT3 troponin T type 3 (skeletal, fast) 1.44581
IMPACT impact RWD domain protein 1.44396
ZNF146 zinc finger protein 146 1.44112
STARD3 StAR-related lipid transfer (START) domain containing 3 1.43845
PGAP3 post-GPI attachment to proteins 3 1.42715
ZNF571 zinc finger protein 571 1.42536
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.42172
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.41809

low expression

Symbol Name Standardized Value
ZC3H15 zinc finger CCCH-type containing 15 -3.53725
FPGS folylpolyglutamate synthase -3.53346
ORAI2 ORAI calcium release-activated calcium modulator 2 -3.48998
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.745
C2CD2L C2CD2-like -2.69684
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 -2.60608
MANF mesencephalic astrocyte-derived neurotrophic factor -2.60116
PLCL2 phospholipase C-like 2 -2.59074
ZNHIT1 zinc finger, HIT-type containing 1 -2.5383
TRPC5 transient receptor potential cation channel, subfamily C, member 5 -2.48109
COL13A1 collagen, type XIII, alpha 1 -2.4564
HSPB1 heat shock 27kDa protein 1 -2.40613
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 -2.33113
CNN3 calponin 3, acidic -2.22382
ALOX5 arachidonate 5-lipoxygenase -2.21145
CIDEB cell death-inducing DFFA-like effector b -2.10657
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.09006
CBX5 chromobox homolog 5 -2.07675
LAPTM5 lysosomal protein transmembrane 5 -2.05739
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.00585
ACOX2 acyl-CoA oxidase 2, branched chain -1.95983
ULK2 unc-51 like autophagy activating kinase 2 -1.95236
IL2RG interleukin 2 receptor, gamma -1.92436
HSPA6 heat shock 70kDa protein 6 (HSP70B') -1.9207
TRIM31 tripartite motif containing 31 -1.90646
FAM214B family with sequence similarity 214, member B -1.87611
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.87362
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -1.86639
PLK3 polo-like kinase 3 -1.86241
LGSN lengsin, lens protein with glutamine synthetase domain -1.85974
ASPHD1 aspartate beta-hydroxylase domain containing 1 -1.84302
ITGAV integrin, alpha V -1.84002
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -1.83815
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -1.82942
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa -1.82443
FAM96B family with sequence similarity 96, member B -1.82299
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -1.80474
ADRA1A adrenoceptor alpha 1A -1.78465
LOXL2 lysyl oxidase-like 2 -1.75587
PAPD4 PAP associated domain containing 4 -1.7555
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -1.74541
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked -1.73898
KIAA0754 KIAA0754 -1.73583
VNN1 vanin 1 -1.72671
NRG2 neuregulin 2 -1.71486
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -1.71188
HAS2 hyaluronan synthase 2 -1.71116
PTGDR2 prostaglandin D2 receptor 2 -1.70768
LOC81691 exonuclease NEF-sp -1.70586
IFT54 intraflagellar transport 54 -1.70203
ZDHHC24 zinc finger, DHHC-type containing 24 -1.69115
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -1.67841
MAGEC3 melanoma antigen family C3 -1.67255
HIST1H2AM histone cluster 1, H2am -1.66053
PFDN2 prefoldin subunit 2 -1.65386
COPS8 COP9 signalosome subunit 8 -1.63414
MAP7D1 MAP7 domain containing 1 -1.63039
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.62057
CREB5 cAMP responsive element binding protein 5 -1.62028
HHEX hematopoietically expressed homeobox -1.60915
FLNC filamin C, gamma -1.59965
CSNK1E casein kinase 1, epsilon -1.59225
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -1.59207
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -1.59018
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -1.58918
NPFFR1 neuropeptide FF receptor 1 -1.58633
ZNF3 zinc finger protein 3 -1.5857
CAPN10 calpain 10 -1.58175
PCDHGA10 protocadherin gamma subfamily A, 10 -1.56777
CCL13 chemokine (C-C motif) ligand 13 -1.5652
DCLK2 doublecortin-like kinase 2 -1.55756
ORC5 origin recognition complex, subunit 5 -1.55739
HCG4B HLA complex group 4B (non-protein coding) -1.55633
TSPYL5 TSPY-like 5 -1.54995
CEP164 centrosomal protein 164kDa -1.54969
ART1 ADP-ribosyltransferase 1 -1.54428
CD209 CD209 molecule -1.5388
PARL presenilin associated, rhomboid-like -1.52884
WNT1 wingless-type MMTV integration site family, member 1 -1.52845
GPR65 G protein-coupled receptor 65 -1.52464
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -1.5208
B3GAT3 beta-1,3-glucuronyltransferase 3 -1.5206
NOX1 NADPH oxidase 1 -1.51923
OCM oncomodulin -1.51843
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -1.51781
KIAA1033 KIAA1033 -1.51707
STK25 serine/threonine kinase 25 -1.51549
CEND1 cell cycle exit and neuronal differentiation 1 -1.50951
TGOLN2 trans-golgi network protein 2 -1.50638
LCAT lecithin-cholesterol acyltransferase -1.50467
RTN2 reticulon 2 -1.49348
KIAA1456 KIAA1456 -1.48611
PTGIS prostaglandin I2 (prostacyclin) synthase -1.48031
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -1.48011
LHX5 LIM homeobox 5 -1.47545
GPR3 G protein-coupled receptor 3 -1.47302
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -1.4654
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -1.46312
GSPT1 G1 to S phase transition 1 -1.45912
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -1.45008
SNCG synuclein, gamma (breast cancer-specific protein 1) -1.44023
KISS1 KiSS-1 metastasis-suppressor -1.44023
SEH1L SEH1-like (S. cerevisiae) -1.43883
OR2B2 olfactory receptor, family 2, subfamily B, member 2 -1.43755
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -1.43485
EPO erythropoietin -1.43364
AGFG2 ArfGAP with FG repeats 2 -1.43165
SPIN2A spindlin family, member 2A -1.43151
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.43112
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.42691
INE1 inactivation escape 1 (non-protein coding) -1.42501
A4GALT alpha 1,4-galactosyltransferase -1.4238
PGM3 phosphoglucomutase 3 -1.42329
CA4 carbonic anhydrase IV -1.4218
COPS6 COP9 signalosome subunit 6 -1.42105
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -1.41882