TE-8 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description A immortal human esophagus-derived cell line cell that has the characteristics: Human cell line derived from esophageal cancer. Moderately differentiated squamous cell carcinoma. TKG0259(Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051371)
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Genes

228 genes with high or low expression in TE-8 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CCDC6 coiled-coil domain containing 6 3.28253
TBC1D13 TBC1 domain family, member 13 3.03258
NRBF2 nuclear receptor binding factor 2 2.7798
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 2.56567
ZNF16 zinc finger protein 16 2.45679
CYHR1 cysteine/histidine-rich 1 2.44429
MRPS11 mitochondrial ribosomal protein S11 2.31911
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 2.31845
DEFB126 defensin, beta 126 2.30313
CCL7 chemokine (C-C motif) ligand 7 2.28097
ZNF7 zinc finger protein 7 2.26651
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.23852
JMJD1C jumonji domain containing 1C 2.2085
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 2.18282
MAN1B1 mannosidase, alpha, class 1B, member 1 2.16138
SEC61G Sec61 gamma subunit 2.15876
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.15584
LIN37 lin-37 DREAM MuvB core complex component 2.12832
SNUPN snurportin 1 2.12526
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 2.11608
SIRT3 sirtuin 3 2.09574
AK1 adenylate kinase 1 2.08762
PDLIM7 PDZ and LIM domain 7 (enigma) 2.07593
FBXO2 F-box protein 2 2.06423
TBC1D2 TBC1 domain family, member 2 2.06268
COPE coatomer protein complex, subunit epsilon 2.05162
IGF1R insulin-like growth factor 1 receptor 2.04538
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 2.0421
HYAL3 hyaluronoglucosaminidase 3 2.02195
SPTAN1 spectrin, alpha, non-erythrocytic 1 2.01376
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.98982
UBAC1 UBA domain containing 1 1.96764
VAMP3 vesicle-associated membrane protein 3 1.94867
SH3GL1 SH3-domain GRB2-like 1 1.94578
ZNF365 zinc finger protein 365 1.94557
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 1.94368
MORF4L1 mortality factor 4 like 1 1.93821
UNC45A unc-45 homolog A (C. elegans) 1.93746
EDC3 enhancer of mRNA decapping 3 1.92311
TOR1B torsin family 1, member B (torsin B) 1.92162
ACP2 acid phosphatase 2, lysosomal 1.9152
GNB5 guanine nucleotide binding protein (G protein), beta 5 1.91401
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.89856
HIST1H2BG histone cluster 1, H2bg 1.8773
MAP2K2 mitogen-activated protein kinase kinase 2 1.8646
BTBD1 BTB (POZ) domain containing 1 1.86037
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.85075
PARK7 parkinson protein 7 1.84637
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 1.84423
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.84153
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.83996
ELP4 elongator acetyltransferase complex subunit 4 1.83855
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.83293
DOLK dolichol kinase 1.82366
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.81383
KIAA1614 KIAA1614 1.81023
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 1.80497
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 1.80004
TNRC6B trinucleotide repeat containing 6B 1.79634
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.79574
FAM53C family with sequence similarity 53, member C 1.78955
PRPF4 pre-mRNA processing factor 4 1.77476
KCTD17 potassium channel tetramerization domain containing 17 1.77422
NANS N-acetylneuraminic acid synthase 1.75143
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 1.74331
VWA1 von Willebrand factor A domain containing 1 1.7352
ARID5B AT rich interactive domain 5B (MRF1-like) 1.73179
PEPD peptidase D 1.73134
FKBP15 FK506 binding protein 15, 133kDa 1.72133
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.70878
PCDHGB5 protocadherin gamma subfamily B, 5 1.70742
CCL8 chemokine (C-C motif) ligand 8 1.69713
PHF20L1 PHD finger protein 20-like 1 1.68512
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 1.68491
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.68389
WRAP73 WD repeat containing, antisense to TP73 1.6779
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.66883
CAPNS1 calpain, small subunit 1 1.66708
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.65214
INVS inversin 1.64934
DOLPP1 dolichyldiphosphatase 1 1.64866
PCYOX1L prenylcysteine oxidase 1 like 1.64531
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.6405
APTX aprataxin 1.63399
RER1 retention in endoplasmic reticulum sorting receptor 1 1.62851
IQGAP1 IQ motif containing GTPase activating protein 1 1.62786
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 1.62571
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.61957
PPME1 protein phosphatase methylesterase 1 1.60881
BRD3 bromodomain containing 3 1.60834
CLSTN1 calsyntenin 1 1.60773
CIZ1 CDKN1A interacting zinc finger protein 1 1.60682
CISD1 CDGSH iron sulfur domain 1 1.60472
HSPA2 heat shock 70kDa protein 2 1.60168
SCAMP2 secretory carrier membrane protein 2 1.59741
MED27 mediator complex subunit 27 1.59301
MTNR1B melatonin receptor 1B 1.59301
BOK BCL2-related ovarian killer 1.58872
SIRT2 sirtuin 2 1.5874
ALAD aminolevulinate dehydratase 1.5802
FADD Fas (TNFRSF6)-associated via death domain 1.56867
NAGK N-acetylglucosamine kinase 1.5639
PEX10 peroxisomal biogenesis factor 10 1.56
ZNF250 zinc finger protein 250 1.55663
GDF11 growth differentiation factor 11 1.55344
ZER1 zyg-11 related, cell cycle regulator 1.54992
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.54813
HRAS Harvey rat sarcoma viral oncogene homolog 1.54745
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 1.54561
DNM1 dynamin 1 1.54543
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.53789
ZSCAN31 zinc finger and SCAN domain containing 31 1.53781
CALML3 calmodulin-like 3 1.53594
COL5A3 collagen, type V, alpha 3 1.5357
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.53461
ARMC9 armadillo repeat containing 9 1.53365
SYNM synemin, intermediate filament protein 1.53345
MMP11 matrix metallopeptidase 11 1.51247
TCEA2 transcription elongation factor A (SII), 2 1.512
RNF139 ring finger protein 139 1.51102
THOC5 THO complex 5 1.50997
KRT75 keratin 75, type II 1.50756
PPAP2A phosphatidic acid phosphatase type 2A 1.50594
MFGE8 milk fat globule-EGF factor 8 protein 1.5041
ACOT7 acyl-CoA thioesterase 7 1.49963
MYL9 myosin, light chain 9, regulatory 1.49616
ICMT isoprenylcysteine carboxyl methyltransferase 1.49449
NELFCD negative elongation factor complex member C/D 1.49109
IFNA16 interferon, alpha 16 1.49046
NMB neuromedin B 1.48925
RXRA retinoid X receptor, alpha 1.48687
RFXANK regulatory factor X-associated ankyrin-containing protein 1.48478
PPP6R2 protein phosphatase 6, regulatory subunit 2 1.47113
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) 1.47065
KIAA0196 KIAA0196 1.46812
CTSV cathepsin V 1.46603
CSDC2 cold shock domain containing C2, RNA binding 1.46431
GAPVD1 GTPase activating protein and VPS9 domains 1 1.46408
TPM2 tropomyosin 2 (beta) 1.46259
PVALB parvalbumin 1.45962
TMEM110 transmembrane protein 110 1.44894
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.44812
NUTF2 nuclear transport factor 2 1.43434
PKM pyruvate kinase, muscle 1.43219
NCLN nicalin 1.43166
WDR61 WD repeat domain 61 1.43046
SH3GL3 SH3-domain GRB2-like 3 1.42605
EFNB3 ephrin-B3 1.42193
PSEN1 presenilin 1 1.4176

low expression

Symbol Name Standardized Value
NFYA nuclear transcription factor Y, alpha -2.84518
UBA6 ubiquitin-like modifier activating enzyme 6 -2.84267
MAK16 MAK16 homolog (S. cerevisiae) -2.64013
RAB28 RAB28, member RAS oncogene family -2.4702
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -2.46622
SETD3 SET domain containing 3 -2.42067
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -2.38812
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.28086
DNAH3 dynein, axonemal, heavy chain 3 -2.23255
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.20567
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.18978
PDS5A PDS5 cohesin associated factor A -2.18913
CAPN9 calpain 9 -2.14806
TRAPPC8 trafficking protein particle complex 8 -2.05186
DDIT3 DNA-damage-inducible transcript 3 -2.0371
LONRF1 LON peptidase N-terminal domain and ring finger 1 -2.01666
TMEM33 transmembrane protein 33 -2.00914
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.99753
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.97594
RAB33A RAB33A, member RAS oncogene family -1.96397
CHIC2 cysteine-rich hydrophobic domain 2 -1.90225
LEFTY2 left-right determination factor 2 -1.89732
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -1.87922
DCTN6 dynactin 6 -1.8786
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -1.85606
THAP1 THAP domain containing, apoptosis associated protein 1 -1.83661
KRT9 keratin 9, type I -1.78273
IL23A interleukin 23, alpha subunit p19 -1.78064
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -1.77445
SDAD1 SDA1 domain containing 1 -1.7417
KLHL28 kelch-like family member 28 -1.72737
PCGF3 polycomb group ring finger 3 -1.71542
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -1.71325
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -1.70611
ELOVL6 ELOVL fatty acid elongase 6 -1.69875
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -1.69112
LYPLA1 lysophospholipase I -1.67812
ZNF395 zinc finger protein 395 -1.66248
CTBS chitobiase, di-N-acetyl- -1.65553
ZNF549 zinc finger protein 549 -1.64296
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -1.63772
STAG3 stromal antigen 3 -1.63591
UBE2K ubiquitin-conjugating enzyme E2K -1.62736
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 -1.61444
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -1.6132
CCDC14 coiled-coil domain containing 14 -1.60496
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -1.58795
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.58528
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -1.58318
RCOR3 REST corepressor 3 -1.5827
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -1.5747
HNF1A HNF1 homeobox A -1.57468
IRAK4 interleukin-1 receptor-associated kinase 4 -1.57223
SCAND2P SCAN domain containing 2 pseudogene -1.56997
NME3 NME/NM23 nucleoside diphosphate kinase 3 -1.56759
FBXO9 F-box protein 9 -1.56232
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -1.55893
MED18 mediator complex subunit 18 -1.54361
LSM1 LSM1, U6 small nuclear RNA associated -1.53839
FOLR1 folate receptor 1 (adult) -1.52702
ARHGAP35 Rho GTPase activating protein 35 -1.52145
CTH cystathionine gamma-lyase -1.52065
PCLO piccolo presynaptic cytomatrix protein -1.51021
DCK deoxycytidine kinase -1.5017
CHML choroideremia-like (Rab escort protein 2) -1.50099
SRP72 signal recognition particle 72kDa -1.4956
SIKE1 suppressor of IKBKE 1 -1.48487
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -1.48168
BAG5 BCL2-associated athanogene 5 -1.4796
ZNF10 zinc finger protein 10 -1.47451
ESRRG estrogen-related receptor gamma -1.46139
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -1.4576
RIOK3 RIO kinase 3 -1.45077
TTC27 tetratricopeptide repeat domain 27 -1.44311
SS18 synovial sarcoma translocation, chromosome 18 -1.44165
SOS2 son of sevenless homolog 2 (Drosophila) -1.437
AADAC arylacetamide deacetylase -1.43204
FNTA farnesyltransferase, CAAX box, alpha -1.42783
FBXO4 F-box protein 4 -1.42329