TE-9 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description A immortal human esophagus-derived cell line cell that has the characteristics: Human esophageal squamous cell carcinoma (poorly differentiated) cell line. Not transplantable to nude mouse. TKG0260 (Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051379)
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Genes

271 genes with high or low expression in TE-9 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 2.72615
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.55252
GMPR2 guanosine monophosphate reductase 2 2.4599
ATF7IP2 activating transcription factor 7 interacting protein 2 2.4167
KRT4 keratin 4, type II 2.39772
FADD Fas (TNFRSF6)-associated via death domain 2.38913
AFG3L2 AFG3-like AAA ATPase 2 2.38505
TLR5 toll-like receptor 5 2.34066
RNASEH2A ribonuclease H2, subunit A 2.31899
TTC23 tetratricopeptide repeat domain 23 2.31653
GEMIN4 gem (nuclear organelle) associated protein 4 2.31104
OXA1L oxidase (cytochrome c) assembly 1-like 2.28888
THADA thyroid adenoma associated 2.24053
CHD8 chromodomain helicase DNA binding protein 8 2.21133
TNK1 tyrosine kinase, non-receptor, 1 2.15957
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.12905
CNOT1 CCR4-NOT transcription complex, subunit 1 2.10228
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.09124
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.08079
PARP2 poly (ADP-ribose) polymerase 2 2.02763
ALPPL2 alkaline phosphatase, placental-like 2 2.01885
PLD2 phospholipase D2 2.0093
DAO D-amino-acid oxidase 1.96616
PADI3 peptidyl arginine deiminase, type III 1.94257
LY6D lymphocyte antigen 6 complex, locus D 1.9325
UBAC1 UBA domain containing 1 1.93224
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.90257
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 1.88194
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.88141
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.87337
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 1.85779
KLF15 Kruppel-like factor 15 1.85546
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.85276
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.8376
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 1.83723
RPUSD2 RNA pseudouridylate synthase domain containing 2 1.81024
RPL3L ribosomal protein L3-like 1.80168
SAGE1 sarcoma antigen 1 1.79957
EIF3D eukaryotic translation initiation factor 3, subunit D 1.79142
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 1.79011
MSLN mesothelin 1.78783
NPC2 Niemann-Pick disease, type C2 1.7834
TP53TG1 TP53 target 1 (non-protein coding) 1.7724
CROCC ciliary rootlet coiled-coil, rootletin 1.77105
ASB4 ankyrin repeat and SOCS box containing 4 1.74689
SLC39A2 solute carrier family 39 (zinc transporter), member 2 1.73967
DUOX1 dual oxidase 1 1.73956
MUC4 mucin 4, cell surface associated 1.73838
RBM23 RNA binding motif protein 23 1.73498
EPB42 erythrocyte membrane protein band 4.2 1.73473
COQ9 coenzyme Q9 1.72572
KLK13 kallikrein-related peptidase 13 1.72232
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.71635
KRT13 keratin 13, type I 1.68649
RNF122 ring finger protein 122 1.68627
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.68618
INVS inversin 1.66072
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.65576
PRSS21 protease, serine, 21 (testisin) 1.65508
ETFB electron-transfer-flavoprotein, beta polypeptide 1.65456
FZD10 frizzled class receptor 10 1.63981
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.63838
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.636
TOP2A topoisomerase (DNA) II alpha 170kDa 1.62249
MPPED2 metallophosphoesterase domain containing 2 1.61685
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 1.60869
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 1.60852
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 1.59949
PLA2G2E phospholipase A2, group IIE 1.59942
GPKOW G patch domain and KOW motifs 1.59685
RPL35 ribosomal protein L35 1.58457
PPP1R12B protein phosphatase 1, regulatory subunit 12B 1.58258
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 1.58175
VRK1 vaccinia related kinase 1 1.58157
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 1.58076
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 1.57571
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 1.57246
CHAF1A chromatin assembly factor 1, subunit A (p150) 1.56727
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 1.56172
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 1.55892
BIK BCL2-interacting killer (apoptosis-inducing) 1.55861
CELA3B chymotrypsin-like elastase family, member 3B 1.55798
GSTP1 glutathione S-transferase pi 1 1.55481
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 1.5543
MMP13 matrix metallopeptidase 13 1.54968
THTPA thiamine triphosphatase 1.5494
KLK11 kallikrein-related peptidase 11 1.54297
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.54153
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.53757
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 1.53652
ACACA acetyl-CoA carboxylase alpha 1.5313
DOC2A double C2-like domains, alpha 1.52752
DLK2 delta-like 2 homolog (Drosophila) 1.52711
PALM paralemmin 1.52639
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 1.5198
HCG26 HLA complex group 26 (non-protein coding) 1.51915
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 1.51631
SUSD4 sushi domain containing 4 1.51434
ALPL alkaline phosphatase, liver/bone/kidney 1.51225
FAT2 FAT atypical cadherin 2 1.50643
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 1.50598
KRT5 keratin 5, type II 1.4996
RNPEP arginyl aminopeptidase (aminopeptidase B) 1.49534
GALR3 galanin receptor 3 1.48768
OLFML2A olfactomedin-like 2A 1.48471
CALB1 calbindin 1, 28kDa 1.48423
TBC1D22A TBC1 domain family, member 22A 1.48306
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.47724
AQP3 aquaporin 3 (Gill blood group) 1.47712
CDK18 cyclin-dependent kinase 18 1.47021
FLOT2 flotillin 2 1.46805
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 1.46775
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.46615
IER2 immediate early response 2 1.46484
CEL carboxyl ester lipase 1.46344
OPRM1 opioid receptor, mu 1 1.45066
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 1.44792
ZFR2 zinc finger RNA binding protein 2 1.4477
CTTN cortactin 1.44666
PCDHA5 protocadherin alpha 5 1.44361
HOXD12 homeobox D12 1.4397
CDH5 cadherin 5, type 2 (vascular endothelium) 1.43621
KLK8 kallikrein-related peptidase 8 1.43202
RIBC2 RIB43A domain with coiled-coils 2 1.43137
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 1.42786
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.42748
TRAP1 TNF receptor-associated protein 1 1.42732
RAD51 RAD51 recombinase 1.42614
SSH3 slingshot protein phosphatase 3 1.42595
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 1.42569
PRC1 protein regulator of cytokinesis 1 1.42244
EGFL6 EGF-like-domain, multiple 6 1.42197
RPP25 ribonuclease P/MRP 25kDa subunit 1.41836

low expression

Symbol Name Standardized Value
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -3.21807
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -3.14916
SEC24A SEC24 family member A -2.81187
SCN11A sodium channel, voltage gated, type XI alpha subunit -2.78217
NFYA nuclear transcription factor Y, alpha -2.7445
ATF6B activating transcription factor 6 beta -2.65773
TRIM23 tripartite motif containing 23 -2.61834
GDAP2 ganglioside induced differentiation associated protein 2 -2.59168
SEC61G Sec61 gamma subunit -2.53765
YAF2 YY1 associated factor 2 -2.50144
USP15 ubiquitin specific peptidase 15 -2.48041
KIF2A kinesin heavy chain member 2A -2.4167
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -2.41004
HUS1 HUS1 checkpoint homolog (S. pombe) -2.35917
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -2.32332
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.29015
RNF25 ring finger protein 25 -2.26799
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.26211
UBE2K ubiquitin-conjugating enzyme E2K -2.21264
CHUK conserved helix-loop-helix ubiquitous kinase -2.20982
SLC16A6 solute carrier family 16, member 6 -2.17618
ANAPC10 anaphase promoting complex subunit 10 -2.15162
SIRT1 sirtuin 1 -2.14172
USF2 upstream transcription factor 2, c-fos interacting -2.11664
BMI1 BMI1 proto-oncogene, polycomb ring finger -2.10199
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -2.08859
RAB5A RAB5A, member RAS oncogene family -2.05814
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -2.05341
HEXA hexosaminidase A (alpha polypeptide) -2.0482
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 -2.03385
SATL1 spermidine/spermine N1-acetyl transferase-like 1 -2.033
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -2.02963
DCAF13 DDB1 and CUL4 associated factor 13 -2.02808
ZNF468 zinc finger protein 468 -2.02215
HIPK1 homeodomain interacting protein kinase 1 -2.00562
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -1.99181
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) -1.98368
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -1.97625
IFT81 intraflagellar transport 81 -1.97585
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -1.96689
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -1.95561
VN1R1 vomeronasal 1 receptor 1 -1.94617
NOL6 nucleolar protein 6 (RNA-associated) -1.9389
ERBB2IP erbb2 interacting protein -1.9318
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.92801
COX11 COX11 cytochrome c oxidase copper chaperone -1.92294
AGFG1 ArfGAP with FG repeats 1 -1.9169
WDR48 WD repeat domain 48 -1.91338
CRYBB2 crystallin, beta B2 -1.90161
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 -1.89397
ZNF292 zinc finger protein 292 -1.8914
CALU calumenin -1.86317
ZFP37 ZFP37 zinc finger protein -1.85912
UFM1 ubiquitin-fold modifier 1 -1.83829
BRAF B-Raf proto-oncogene, serine/threonine kinase -1.83602
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -1.81897
GAB2 GRB2-associated binding protein 2 -1.80865
ZNF143 zinc finger protein 143 -1.80737
ZNF573 zinc finger protein 573 -1.80188
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -1.78996
TMEM33 transmembrane protein 33 -1.78901
PRPF18 pre-mRNA processing factor 18 -1.78824
MED8 mediator complex subunit 8 -1.78717
LINS lines homolog (Drosophila) -1.78169
PTN pleiotrophin -1.78049
ZNF430 zinc finger protein 430 -1.77481
CCDC90B coiled-coil domain containing 90B -1.77207
LOC155060 AI894139 pseudogene -1.77044
SLC25A51 solute carrier family 25, member 51 -1.75251
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -1.73887
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -1.72743
KIAA1033 KIAA1033 -1.72631
PCNP PEST proteolytic signal containing nuclear protein -1.72539
VCP valosin containing protein -1.72266
FANCF Fanconi anemia, complementation group F -1.71689
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -1.6815
SOS2 son of sevenless homolog 2 (Drosophila) -1.68074
VEZF1 vascular endothelial zinc finger 1 -1.6666
SMAD2 SMAD family member 2 -1.66534
RNF115 ring finger protein 115 -1.6637
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -1.65709
PPP5C protein phosphatase 5, catalytic subunit -1.65439
ZNF202 zinc finger protein 202 -1.64604
SON SON DNA binding protein -1.64339
TLR4 toll-like receptor 4 -1.64186
DISC1 disrupted in schizophrenia 1 -1.63826
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.63645
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -1.6322
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.63185
CASD1 CAS1 domain containing 1 -1.62756
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -1.6234
ZNF432 zinc finger protein 432 -1.62202
KCTD5 potassium channel tetramerization domain containing 5 -1.61912
MEF2D myocyte enhancer factor 2D -1.61153
PITRM1 pitrilysin metallopeptidase 1 -1.61101
SMG5 SMG5 nonsense mediated mRNA decay factor -1.60675
RAB28 RAB28, member RAS oncogene family -1.60541
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -1.60415
ZFP30 ZFP30 zinc finger protein -1.60213
SETD4 SET domain containing 4 -1.60105
VLDLR very low density lipoprotein receptor -1.5956
TMEM104 transmembrane protein 104 -1.59126
KIN Kin17 DNA and RNA binding protein -1.58982
UBA2 ubiquitin-like modifier activating enzyme 2 -1.58745
HSPA13 heat shock protein 70kDa family, member 13 -1.58586
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -1.58396
IGFBP4 insulin-like growth factor binding protein 4 -1.57249
ZMYM5 zinc finger, MYM-type 5 -1.56921
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.56357
CHMP5 charged multivesicular body protein 5 -1.55915
ZNF207 zinc finger protein 207 -1.54278
ZNF443 zinc finger protein 443 -1.54005
PPID peptidylprolyl isomerase D -1.53516
ARF4 ADP-ribosylation factor 4 -1.53181
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -1.53138
GPATCH3 G patch domain containing 3 -1.53098
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -1.52891
FBXO22 F-box protein 22 -1.52518
BCAS2 breast carcinoma amplified sequence 2 -1.52112
ZNF8 zinc finger protein 8 -1.51859
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -1.50748
RIF1 replication timing regulatory factor 1 -1.50459
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) -1.50358
CD79B CD79b molecule, immunoglobulin-associated beta -1.4991
POMT2 protein-O-mannosyltransferase 2 -1.49635
NUPL1 nucleoporin like 1 -1.48683
MTMR6 myotubularin related protein 6 -1.47642
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -1.47586
ZNF20 zinc finger protein 20 -1.46813
SIKE1 suppressor of IKBKE 1 -1.46362
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -1.4516
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -1.45097
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -1.4405
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.42838
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -1.42296
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) -1.42216
SEC23IP SEC23 interacting protein -1.42022
RAB6A RAB6A, member RAS oncogene family -1.41707