TE6 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
Description Esophageal Squamous Cell Carcinoma cell line (Cancer Dependency Map)
External Link https://depmap.org/portal/cell_line/ACH-000605
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Genes

686 gene knockdowns changing fitness of TE6 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
CASQ2 calsequestrin 2 (cardiac muscle) 13.384
HIBADH 3-hydroxyisobutyrate dehydrogenase 12.0337
CRACR2A calcium release activated channel regulator 2A 9.63421
SYN1 synapsin I 9.19545
WNT2B wingless-type MMTV integration site family, member 2B 9.13462
PNPLA1 patatin-like phospholipase domain containing 1 8.55586
CTSC cathepsin C 8.27218
NRN1 neuritin 1 8.0679
ZNF768 zinc finger protein 768 7.86724
C8B complement component 8, beta polypeptide 7.69656
ABHD2 abhydrolase domain containing 2 7.66804
PROK1 prokineticin 1 7.64156
GSTM5 glutathione S-transferase mu 5 7.51372
PLSCR2 phospholipid scramblase 2 7.50678
MMP2 matrix metallopeptidase 2 7.33914
CD101 CD101 molecule 7.21355
H1-10 H1.10 linker histone 7.09361
TRPM6 transient receptor potential cation channel, subfamily M, member 6 6.99806
NOTCH2 notch 2 6.97858
HBEGF heparin-binding EGF-like growth factor 6.96819
SIGLEC6 sialic acid binding Ig-like lectin 6 6.76814
ANO1 anoctamin 1, calcium activated chloride channel 6.74626
HOXD4 homeobox D4 6.6132
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 6.60938
RAB8A RAB8A, member RAS oncogene family 6.49311
MEST mesoderm specific transcript 6.46727
SDCBP syndecan binding protein (syntenin) 6.41567
TEX14 testis expressed 14 6.35561
ADSS1 adenylosuccinate synthase 1 6.28892
DSC1 desmocollin 1 6.1825
TAOK2 TAO kinase 2 6.16136
TAS2R14 taste receptor, type 2, member 14 6.11944
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 6.07921
HOXA5 homeobox A5 6.03603
CCNO cyclin O 5.96699
FAM102B family with sequence similarity 102, member B 5.91895
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 5.86685
FBXL14 F-box and leucine-rich repeat protein 14 5.86439
MYEOV myeloma overexpressed 5.82021
FGR FGR proto-oncogene, Src family tyrosine kinase 5.79863
SCN8A sodium channel, voltage gated, type VIII alpha subunit 5.77576
CSF1 colony stimulating factor 1 (macrophage) 5.77448
VSX1 visual system homeobox 1 5.77188
TRIM45 tripartite motif containing 45 5.67922
EMB embigin 5.67546
STEAP1 six transmembrane epithelial antigen of the prostate 1 5.67483
OR5B17 olfactory receptor, family 5, subfamily B, member 17 5.66005
L3HYPDH L-3-hydroxyproline dehydratase (trans-) 5.65705
TULP3 tubby like protein 3 5.59686
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 5.57267
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J 5.56641
VWA7 von Willebrand factor A domain containing 7 5.51492
PCGF5 polycomb group ring finger 5 5.48814
SYPL2 synaptophysin-like 2 5.48051
KMT5C lysine methyltransferase 5C 5.45965
GPR12 G protein-coupled receptor 12 5.42064
TOR1A torsin family 1, member A (torsin A) 5.36454
VANGL1 VANGL planar cell polarity protein 1 5.31966
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 5.31695
C1ORF53 chromosome 1 open reading frame 53 5.27192
ACOT8 acyl-CoA thioesterase 8 5.25176
ROM1 retinal outer segment membrane protein 1 5.24834
METTL21C methyltransferase like 21C 5.17086
LRP2BP LRP2 binding protein 5.12478
STIM2 stromal interaction molecule 2 5.11869
GSTM4 glutathione S-transferase mu 4 5.09476
PPP1R13B protein phosphatase 1, regulatory subunit 13B 5.05193
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 5.00726
TANK TRAF family member-associated NFKB activator 4.94775
ZNF346 zinc finger protein 346 4.94123
AKAP8 A kinase (PRKA) anchor protein 8 4.93471
RASL11A RAS-like, family 11, member A 4.87782
SORT1 sortilin 1 4.87094
STRIP2 striatin interacting protein 2 4.86758
CTTNBP2NL CTTNBP2 N-terminal like 4.86636
OR10R2 olfactory receptor, family 10, subfamily R, member 2 4.83238
TSLP thymic stromal lymphopoietin 4.81876
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 4.79371
CXCL14 chemokine (C-X-C motif) ligand 14 4.75655
SLC25A43 solute carrier family 25, member 43 4.72336
SIKE1 suppressor of IKBKE 1 4.71048
CCDC124 coiled-coil domain containing 124 4.67173
SSH2 slingshot protein phosphatase 2 4.67132
EFCC1 EF-hand and coiled-coil domain containing 1 4.65278
SLC16A4 solute carrier family 16, member 4 4.63081
CUBN cubilin (intrinsic factor-cobalamin receptor) 4.62523
KRT80 keratin 80, type II 4.59864
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 4.56148
C1ORF100 chromosome 1 open reading frame 100 4.54252
ATCAY ataxia, cerebellar, Cayman type 4.53871
ATXN7L2 ataxin 7-like 2 4.53711
ADAMTSL3 ADAMTS-like 3 4.53
MINDY4 MINDY lysine 48 deubiquitinase 4 4.52169
LCMT2 leucine carboxyl methyltransferase 2 4.45215
PNKD paroxysmal nonkinesigenic dyskinesia 4.45088
ZNF22 zinc finger protein 22 4.43792
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) 4.42586
STMN3 stathmin-like 3 4.418
ACBD3 acyl-CoA binding domain containing 3 4.41416
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 4.38802
CARHSP1 calcium regulated heat stable protein 1, 24kDa 4.37506
SLC25A27 solute carrier family 25, member 27 4.34789
FOS FBJ murine osteosarcoma viral oncogene homolog 4.34366
C12ORF73 chromosome 12 open reading frame 73 4.33582
FRMD6 FERM domain containing 6 4.32789
TDRD7 tudor domain containing 7 4.29387
PON2 paraoxonase 2 4.28704
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 4.25997
RIPK4 receptor-interacting serine-threonine kinase 4 4.2456
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 4.22324
C6ORF165 chromosome 6 open reading frame 165 4.21902
CYB561D1 cytochrome b561 family, member D1 4.214
ODF3L2 outer dense fiber of sperm tails 3-like 2 4.21202
SP8 Sp8 transcription factor 4.21146
C1QTNF1 C1q and tumor necrosis factor related protein 1 4.20886
OVGP1 oviductal glycoprotein 1, 120kDa 4.20445
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 4.19893
C6ORF25 chromosome 6 open reading frame 25 4.19752
MS4A10 membrane-spanning 4-domains, subfamily A, member 10 4.16612
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 4.16161
RPGRIP1L RPGRIP1-like 4.16121
FASTKD2 FAST kinase domains 2 4.15799
CDH7 cadherin 7, type 2 4.15502
DENND2C DENN/MADD domain containing 2C 4.13959
C16ORF96 chromosome 16 open reading frame 96 4.1331
SAMD15 sterile alpha motif domain containing 15 4.12028
TBX4 T-box 4 4.1006
STS steroid sulfatase (microsomal), isozyme S 4.10011
MON1B MON1 secretory trafficking family member B 4.08952
ZC2HC1C zinc finger, C2HC-type containing 1C 4.07655
EPPIN epididymal peptidase inhibitor 4.04582
TAPT1 transmembrane anterior posterior transformation 1 4.02859
KIF26A kinesin family member 26A 4.01512
BTBD10 BTB (POZ) domain containing 10 4.01058
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 4.01011
MXD1 MAX dimerization protein 1 3.97096
OR5B3 olfactory receptor, family 5, subfamily B, member 3 3.96929
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 3.96283
GPX2 glutathione peroxidase 2 3.96209
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 3.95882
WNT16 wingless-type MMTV integration site family, member 16 3.93798
MAP6D1 MAP6 domain containing 1 3.92417
ADRA1D adrenoceptor alpha 1D 3.91831
C12ORF66 chromosome 12 open reading frame 66 3.91411
SOX2 SRY (sex determining region Y)-box 2 3.91254
TRIM31 tripartite motif containing 31 3.88502
FNDC7 fibronectin type III domain containing 7 3.8689
FLNC filamin C, gamma 3.85547
LRRC55 leucine rich repeat containing 55 3.84966
SH2D7 SH2 domain containing 7 3.84539
MYH11 myosin, heavy chain 11, smooth muscle 3.82504
HIST1H4C histone cluster 1, H4c 3.81025
BORCS7 BLOC-1 related complex subunit 7 3.80861
ZNF385B zinc finger protein 385B 3.78981
JPH1 junctophilin 1 3.76911
RFPL1 ret finger protein-like 1 3.76822
DUSP18 dual specificity phosphatase 18 3.75573
MMP17 matrix metallopeptidase 17 (membrane-inserted) 3.75469
FGF23 fibroblast growth factor 23 3.74681
CDR2L cerebellar degeneration-related protein 2-like 3.74609
SLMO1 slowmo homolog 1 (Drosophila) 3.73894
C20ORF194 chromosome 20 open reading frame 194 3.72612
ABHD8 abhydrolase domain containing 8 3.71632
KIF21B kinesin family member 21B 3.71255
OPHN1 oligophrenin 1 3.70855
NKAPL NFKB activating protein-like 3.70846
SOCS4 suppressor of cytokine signaling 4 3.7076
CCDC87 coiled-coil domain containing 87 3.69769
MST1R macrophage stimulating 1 receptor 3.69353
EHD3 EH-domain containing 3 3.69333
THAP7 THAP domain containing 7 3.68493
CXCL3 chemokine (C-X-C motif) ligand 3 3.67743
IRF2BPL interferon regulatory factor 2 binding protein-like 3.67714
KRTAP21-2 keratin associated protein 21-2 3.67639
MOBP myelin-associated oligodendrocyte basic protein 3.67394
NR2E1 nuclear receptor subfamily 2, group E, member 1 3.67299
PRX periaxin 3.66083
KANK3 KN motif and ankyrin repeat domains 3 3.64785
TTC30A tetratricopeptide repeat domain 30A 3.64763
HOXD11 homeobox D11 3.64301
EEA1 early endosome antigen 1 3.64144
ITGA1 integrin, alpha 1 3.64111
CPEB1 cytoplasmic polyadenylation element binding protein 1 3.64025
SFT2D1 SFT2 domain containing 1 3.63997
TMEM60 transmembrane protein 60 3.63655
TTC17 tetratricopeptide repeat domain 17 3.63552
FAM205A family with sequence similarity 205, member A 3.63213
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 3.63004
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 3.62358
FAM214A family with sequence similarity 214, member A 3.60871
HTRA2 HtrA serine peptidase 2 3.59405
TRIM9 tripartite motif containing 9 3.5898
LPO lactoperoxidase 3.58581
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 3.56054
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 3.55681
CALML5 calmodulin-like 5 3.55037
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 3.53779
PCDHA11 protocadherin alpha 11 3.53168
IL9 interleukin 9 3.51848
ADCY9 adenylate cyclase 9 3.51498
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 3.51447
ZNF547 zinc finger protein 547 3.50527
PSRC1 proline/serine-rich coiled-coil 1 3.49273
NOS1 nitric oxide synthase 1 (neuronal) 3.48976
HPS5 Hermansky-Pudlak syndrome 5 3.48611
XXYLT1 xyloside xylosyltransferase 1 3.4854
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 3.48122
HMGA2 high mobility group AT-hook 2 3.47341
IFT43 intraflagellar transport 43 3.47338
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 3.46992
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 3.46585
LMBRD1 LMBR1 domain containing 1 3.46365
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 3.45991
SPATA20 spermatogenesis associated 20 3.45955
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.44984
FAM3A family with sequence similarity 3, member A 3.44862
NFE2L2 nuclear factor, erythroid 2-like 2 3.44706
HLF hepatic leukemia factor 3.42548
FBXO31 F-box protein 31 3.41009
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 3.39223
SAXO2 stabilizer of axonemal microtubules 2 3.39034
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 3.3865
CD200R1 CD200 receptor 1 3.37367
TP53TG5 TP53 target 5 3.37335
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 3.37129
MPHOSPH9 M-phase phosphoprotein 9 3.36053
PLD1 phospholipase D1, phosphatidylcholine-specific 3.35773
CORO6 coronin 6 3.3344
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 3.33437
LOXL2 lysyl oxidase-like 2 3.33081
SPAG8 sperm associated antigen 8 3.3205
EDIL3 EGF-like repeats and discoidin I-like domains 3 3.31958
EMP3 epithelial membrane protein 3 3.31544
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.2982
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.29565
PTGIS prostaglandin I2 (prostacyclin) synthase 3.28492
TMEM33 transmembrane protein 33 3.28474
FAM43B family with sequence similarity 43, member B 3.28419
SACK1F scaffolding CK1 anchoring protein F 3.27485
RNF212 ring finger protein 212 3.27034
OR5F1 olfactory receptor, family 5, subfamily F, member 1 3.26482
CCDC169 coiled-coil domain containing 169 3.25616
UTF1 undifferentiated embryonic cell transcription factor 1 3.24653
GDAP2 ganglioside induced differentiation associated protein 2 3.24312
FHL1 four and a half LIM domains 1 3.24032
ASTN1 astrotactin 1 3.23769
RASEF RAS and EF-hand domain containing 3.23756
ZNF263 zinc finger protein 263 3.23324
BCL2L15 BCL2-like 15 3.23187
CNTN2 contactin 2 (axonal) 3.2297
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.22812
RAB4A RAB4A, member RAS oncogene family 3.22451
EHD2 EH-domain containing 2 3.21841
SLC22A15 solute carrier family 22, member 15 3.21794
MMP19 matrix metallopeptidase 19 3.21725
C2ORF76 chromosome 2 open reading frame 76 3.21108
TEX38 testis expressed 38 3.18973
ACVR2B activin A receptor, type IIB 3.18869
MGARP mitochondria-localized glutamic acid-rich protein 3.18751
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 3.16901
KIAA1549 KIAA1549 3.15527
SYTL4 synaptotagmin-like 4 3.14562
OTP orthopedia homeobox 3.13938
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 3.13088
IL4R interleukin 4 receptor 3.12944
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 3.12491
ZNF83 zinc finger protein 83 3.12228
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 3.11384
ECE1 endothelin converting enzyme 1 3.11016
IGFBP3 insulin-like growth factor binding protein 3 3.09787
IQCA1 IQ motif containing with AAA domain 1 3.0875
RAB23 RAB23, member RAS oncogene family 3.08655
SGCE sarcoglycan, epsilon 3.08515
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 3.08391
ADAM21 ADAM metallopeptidase domain 21 3.06085
CDR2 cerebellar degeneration-related protein 2, 62kDa 3.0581
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 3.05805
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 3.04508
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 3.03596
EMC9 ER membrane protein complex subunit 9 3.03367
CCL1 chemokine (C-C motif) ligand 1 3.02016
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 3.01678
LGALS13 lectin, galactoside-binding, soluble, 13 3.01655
AIF1 allograft inflammatory factor 1 3.00701
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.99237
HOXC4 homeobox C4 2.98019
FOXL2NB FOXL2 neighbor 2.97747
LVRN laeverin 2.97511
SMPX small muscle protein, X-linked 2.96821
REM2 RAS (RAD and GEM)-like GTP binding 2 2.96645
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.9635
C1ORF194 chromosome 1 open reading frame 194 2.96302
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.95856
CHI3L2 chitinase 3-like 2 2.95505
VDAC3 voltage-dependent anion channel 3 2.95491
SGPP1 sphingosine-1-phosphate phosphatase 1 2.9523
FRMPD1 FERM and PDZ domain containing 1 2.95193
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.9447
SFRP4 secreted frizzled-related protein 4 2.94002
SELENOW selenoprotein W 2.92908
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.92289
ITGA9 integrin, alpha 9 2.92015
PWWP2A PWWP domain containing 2A 2.91213
ABHD13 abhydrolase domain containing 13 2.91121
TEK TEK tyrosine kinase, endothelial 2.90507
IGSF3 immunoglobulin superfamily, member 3 2.89926
BRSK2 BR serine/threonine kinase 2 2.89742
PTGR1 prostaglandin reductase 1 2.8932
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 2.89271
RNF139 ring finger protein 139 2.89042
ESX1 ESX homeobox 1 2.88958
ACOT4 acyl-CoA thioesterase 4 2.88641
DGCR6 DiGeorge syndrome critical region gene 6 2.88511
DRAM2 DNA-damage regulated autophagy modulator 2 2.87567
NUMB numb homolog (Drosophila) 2.87419
LGALS14 lectin, galactoside-binding, soluble, 14 2.8722
TACSTD2 tumor-associated calcium signal transducer 2 2.86053
WDR47 WD repeat domain 47 2.86009
L3MBTL1 l(3)mbt-like 1 (Drosophila) 2.85968
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 2.85782
UGDH UDP-glucose 6-dehydrogenase 2.84753
OR9G1 olfactory receptor, family 9, subfamily G, member 1 2.8432
REG4 regenerating islet-derived family, member 4 2.84157
ANKRD37 ankyrin repeat domain 37 2.83728
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.82814
PARPBP PARP1 binding protein 2.82461
FMNL2 formin-like 2 2.82124
CIB3 calcium and integrin binding family member 3 2.82068
MICOS13 mitochondrial contact site and cristae organizing system subunit 13 2.82051
ULBP2 UL16 binding protein 2 2.82007
BHMT betaine--homocysteine S-methyltransferase 2.81743
MAST3 microtubule associated serine/threonine kinase 3 2.81099
NRN1L neuritin 1-like 2.80593
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.79114
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 2.78888
CAPRIN1 cell cycle associated protein 1 2.78809
ABHD15 abhydrolase domain containing 15 2.78545
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.78428
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2.78339
CXCL16 chemokine (C-X-C motif) ligand 16 2.78142
ERBB3 erb-b2 receptor tyrosine kinase 3 2.77924
ANKEF1 ankyrin repeat and EF-hand domain containing 1 2.7771
CCDC36 coiled-coil domain containing 36 2.771
FAM26F family with sequence similarity 26, member F 2.76506
GALC galactosylceramidase 2.74194
CLEC4F C-type lectin domain family 4, member F 2.74051
HOXB8 homeobox B8 2.73686
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 2.73404
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.73165
FBXO41 F-box protein 41 2.72981
SNX12 sorting nexin 12 2.72851
ACSBG1 acyl-CoA synthetase bubblegum family member 1 2.72845
PRLR prolactin receptor 2.72363
CARNS1 carnosine synthase 1 2.71719
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.7133
STRA6 stimulated by retinoic acid 6 2.71228
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.7114
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 2.70353
RUSC1 RUN and SH3 domain containing 1 2.69801
HFE hemochromatosis 2.69698
CTNND1 catenin (cadherin-associated protein), delta 1 2.69687
BCO2 beta-carotene oxygenase 2 2.69385
NLGN4X neuroligin 4, X-linked 2.69199
ANKRD13A ankyrin repeat domain 13A 2.68768
SLFN12 schlafen family member 12 2.6875
ACTL8 actin-like 8 2.68543
WASHC2A WASH complex subunit 2A 2.67988
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.6752
AP1M2 adaptor-related protein complex 1, mu 2 subunit 2.67343
KRT6C keratin 6C, type II 2.67214
HOXD9 homeobox D9 2.66464
OR2D3 olfactory receptor, family 2, subfamily D, member 3 2.66067
TMEM139 transmembrane protein 139 2.65789
PTGFR prostaglandin F receptor (FP) 2.6546
LYZ lysozyme 2.6494
ANXA8L1 annexin A8-like 1 2.64494
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.6446
MFSD1 major facilitator superfamily domain containing 1 2.6401
KRTAP13-3 keratin associated protein 13-3 2.63967
CPA4 carboxypeptidase A4 2.63343
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.63327
FYN FYN proto-oncogene, Src family tyrosine kinase 2.631
UBL4B ubiquitin-like 4B 2.62816
MAIP1 matrix AAA peptidase interacting protein 1 2.62786
STARD10 StAR-related lipid transfer (START) domain containing 10 2.62612
FBXL6 F-box and leucine-rich repeat protein 6 2.62402
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 2.61835
TEKT2 tektin 2 (testicular) 2.61652
ESRRB estrogen-related receptor beta 2.61311
PYDC1 PYD (pyrin domain) containing 1 2.60858
NXNL2 nucleoredoxin-like 2 2.60726
HOXA11 homeobox A11 2.60553
BMF Bcl2 modifying factor 2.60291
TMEM177 transmembrane protein 177 2.5896
RSG1 REM2 and RAB-like small GTPase 1 2.5815
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 2.58042
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 2.57657
FADD Fas (TNFRSF6)-associated via death domain 2.57218
DRG2 developmentally regulated GTP binding protein 2 2.5704
STARD4 StAR-related lipid transfer (START) domain containing 4 2.57007
HNMT histamine N-methyltransferase 2.56289
GPATCH2L G patch domain containing 2-like 2.56276
HEATR4 HEAT repeat containing 4 2.55748
SLC7A14 solute carrier family 7, member 14 2.55532
ERCC6L2 excision repair cross-complementation group 6-like 2 2.54689
ZBTB47 zinc finger and BTB domain containing 47 2.54205
IRF6 interferon regulatory factor 6 2.54152
NOS3 nitric oxide synthase 3 (endothelial cell) 2.53061
TSNARE1 t-SNARE domain containing 1 2.5301
PRAMEF12 PRAME family member 12 2.52564
CRABP2 cellular retinoic acid binding protein 2 2.52357
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 2.52145
SPATA2 spermatogenesis associated 2 2.51638
SPAST spastin 2.51497
PARL presenilin associated, rhomboid-like 2.5142
CTSV cathepsin V 2.51238
RMDN2 regulator of microtubule dynamics 2 2.50772
UHRF1BP1 UHRF1 binding protein 1 2.50319
NOD1 nucleotide-binding oligomerization domain containing 1 2.50297
KIAA0586 KIAA0586 2.50238
CLPSL1 colipase-like 1 2.49876
MGST2 microsomal glutathione S-transferase 2 2.49846
NXNL1 nucleoredoxin-like 1 2.49589
REEP1 receptor accessory protein 1 2.49573
ALPL alkaline phosphatase, liver/bone/kidney 2.49195
DRD3 dopamine receptor D3 2.48888
MVB12A multivesicular body subunit 12A 2.48254
NWD1 NACHT and WD repeat domain containing 1 2.48198
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 2.46907
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 2.46906
PSG4 pregnancy specific beta-1-glycoprotein 4 2.46707
SLC46A3 solute carrier family 46, member 3 2.46169
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 2.46091
CDKN2A cyclin-dependent kinase inhibitor 2A 2.46053
FGF6 fibroblast growth factor 6 2.45893
TRMO tRNA methyltransferase O 2.45629
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.45522
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 2.45373
ZNF414 zinc finger protein 414 2.45338
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.4531
MOK MOK protein kinase 2.44941
EMD emerin 2.44537
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.44265
TNNI3K TNNI3 interacting kinase 2.43967
DCAF10 DDB1 and CUL4 associated factor 10 2.43812
TSPAN33 tetraspanin 33 2.43545
GSTK1 glutathione S-transferase kappa 1 2.43484
MTHFSD methenyltetrahydrofolate synthetase domain containing 2.43434
PITX1 paired-like homeodomain 1 2.4321
DENND2A DENN/MADD domain containing 2A 2.43194
KLK13 kallikrein-related peptidase 13 2.43187
WDTC1 WD and tetratricopeptide repeats 1 2.43148
CES5A carboxylesterase 5A 2.43049
NGF nerve growth factor (beta polypeptide) 2.42881
GOLGA6B golgin A6 family, member B 2.42842
SIX1 SIX homeobox 1 2.4248
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.42431
ARSA arylsulfatase A 2.42066
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 2.41969
HEMK1 HemK methyltransferase family member 1 2.41921
ANGEL1 angel homolog 1 (Drosophila) 2.41484
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.41187
AKNAD1 AKNA domain containing 1 2.40843
CARD8 caspase recruitment domain family, member 8 2.40714
TMEM97 transmembrane protein 97 2.40642
BCAS3 breast carcinoma amplified sequence 3 2.40406
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 2.40023
UBN2 ubinuclein 2 2.39599
LBH limb bud and heart development 2.39579
LOXL1 lysyl oxidase-like 1 2.39217
ARG2 arginase 2 2.38988
GAPVD1 GTPase activating protein and VPS9 domains 1 2.38519
OXSR1 oxidative stress responsive 1 2.38431
PTPRM protein tyrosine phosphatase, receptor type, M 2.38321
MYH15 myosin, heavy chain 15 2.38188
ERBB2 erb-b2 receptor tyrosine kinase 2 2.38161
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.38149
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.38148
JAKMIP2 janus kinase and microtubule interacting protein 2 2.38069
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.37866
CCDC96 coiled-coil domain containing 96 2.37618
RAD51AP1 RAD51 associated protein 1 2.37409
SLCO5A1 solute carrier organic anion transporter family, member 5A1 2.37248
TKFC triokinase/FMN cyclase 2.3681
SPATA13 spermatogenesis associated 13 2.36756
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.36726
UGCG UDP-glucose ceramide glucosyltransferase 2.36627
LIX1 Lix1 homolog (chicken) 2.36505
RPUSD3 RNA pseudouridylate synthase domain containing 3 2.35941
CAPN2 calpain 2, (m/II) large subunit 2.35785
SNX33 sorting nexin 33 2.35577
OR8G5 olfactory receptor, family 8, subfamily G, member 5 2.35282
ZSWIM1 zinc finger, SWIM-type containing 1 2.3507
CYB5R2 cytochrome b5 reductase 2 2.34883
TENT4B terminal nucleotidyltransferase 4B 2.34824
RPRML reprimo-like 2.33939
LAPTM4B lysosomal protein transmembrane 4 beta 2.33731
ZNF462 zinc finger protein 462 2.33163
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 2.33135
PCDHA4 protocadherin alpha 4 2.3305
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.32831
MAP7D1 MAP7 domain containing 1 2.32616
PRR19 proline rich 19 2.32383
SNPH syntaphilin 2.32263
WNT5B wingless-type MMTV integration site family, member 5B 2.31639
MSMB microseminoprotein, beta- 2.31425
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 2.31373
BICD1 bicaudal D homolog 1 (Drosophila) 2.31136
HIST1H3F histone cluster 1, H3f 2.31088
ACTL7B actin-like 7B 2.30551
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.30536
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 2.30363
KRT77 keratin 77, type II 2.30131
EML4 echinoderm microtubule associated protein like 4 2.298
DSG2 desmoglein 2 2.298
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 2.29787
GPR34 G protein-coupled receptor 34 2.29741
RNASE11 ribonuclease, RNase A family, 11 (non-active) 2.29618
ZNF675 zinc finger protein 675 2.29522
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 2.29449
NUTM2G NUT family member 2G 2.29392
RBMS2 RNA binding motif, single stranded interacting protein 2 2.28825
TMTC2 transmembrane and tetratricopeptide repeat containing 2 2.28796
ADCY3 adenylate cyclase 3 2.28769
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.28479
IFI44 interferon-induced protein 44 2.28316
CDK20 cyclin-dependent kinase 20 2.28242
WFDC9 WAP four-disulfide core domain 9 2.28075
GRIK4 glutamate receptor, ionotropic, kainate 4 2.28067
LRRC10B leucine rich repeat containing 10B 2.27955
GSTM2 glutathione S-transferase mu 2 (muscle) 2.27348
MYBPHL myosin binding protein H-like 2.27137
LHX6 LIM homeobox 6 2.26897
SIGMAR1 sigma non-opioid intracellular receptor 1 2.26783
LONRF2 LON peptidase N-terminal domain and ring finger 2 2.26615
ZNF530 zinc finger protein 530 2.26334
TM9SF2 transmembrane 9 superfamily member 2 2.26325
RHOC ras homolog family member C 2.26306
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 2.26106
FAM228A family with sequence similarity 228, member A 2.25994
PSD4 pleckstrin and Sec7 domain containing 4 2.25052
TMEM101 transmembrane protein 101 2.24026
FREM2 FRAS1 related extracellular matrix protein 2 2.23767
SYT8 synaptotagmin VIII 2.23655
MTFP1 mitochondrial fission process 1 2.23335
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 2.23252
ABHD5 abhydrolase domain containing 5 2.23251
ZSCAN5A zinc finger and SCAN domain containing 5A 2.2286
MRAS muscle RAS oncogene homolog 2.22857
TK2 thymidine kinase 2, mitochondrial 2.22625
DESI1 desumoylating isopeptidase 1 2.22505
DLEC1 deleted in lung and esophageal cancer 1 2.22501
ZNF148 zinc finger protein 148 2.22488
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.22446
HOXD10 homeobox D10 2.22415
VWDE von Willebrand factor D and EGF domains 2.22296
TSPAN14 tetraspanin 14 2.22293
CDX4 caudal type homeobox 4 2.22244
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.22099
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.22034
MB21D2 Mab-21 domain containing 2 2.21938
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.2183
TIGD7 tigger transposable element derived 7 2.21735
UBXN11 UBX domain protein 11 2.21661
FAM184A family with sequence similarity 184, member A 2.21403
TECPR2 tectonin beta-propeller repeat containing 2 2.20859
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 2.20813
CHURC1 churchill domain containing 1 2.20699
GOPC golgi-associated PDZ and coiled-coil motif containing 2.20474
METRN meteorin, glial cell differentiation regulator 2.20268
KRT35 keratin 35, type I 2.20243
CATSPER1 cation channel, sperm associated 1 2.20085
SIGLEC10 sialic acid binding Ig-like lectin 10 2.1941
PGLS 6-phosphogluconolactonase 2.19342
TRIM60 tripartite motif containing 60 2.19138
FYB1 FYN binding protein 1 2.18837
NT5DC2 5'-nucleotidase domain containing 2 2.18779
JPT1 Jupiter microtubule associated homolog 1 2.1847
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 2.18435
BABAM1 BRISC and BRCA1 A complex member 1 2.18392
TP63 tumor protein p63 2.18317
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.1818
PBX2 pre-B-cell leukemia homeobox 2 2.17476
PSPH phosphoserine phosphatase 2.17415
SHC4 SHC (Src homology 2 domain containing) family, member 4 2.17386
DCXR dicarbonyl/L-xylulose reductase 2.17375
ATP7A ATPase, Cu++ transporting, alpha polypeptide 2.17138
DAP death-associated protein 2.16932
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.1674
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.16735
RIC3 RIC3 acetylcholine receptor chaperone 2.1661
KIF9 kinesin family member 9 2.16327
ZNF579 zinc finger protein 579 2.15912
ERCC5 excision repair cross-complementation group 5 2.15472
NME5 NME/NM23 family member 5 2.15227
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.15212
FAT2 FAT atypical cadherin 2 2.14975
C2ORF68 chromosome 2 open reading frame 68 2.14883
LHCGR luteinizing hormone/choriogonadotropin receptor 2.1451
ERC1 ELKS/RAB6-interacting/CAST family member 1 2.14349
TAS2R46 taste receptor, type 2, member 46 2.14025
MT1F metallothionein 1F 2.13841
THUMPD2 THUMP domain containing 2 2.13828
ADGRE2 adhesion G protein-coupled receptor E2 2.13743
NFE2L3 nuclear factor, erythroid 2-like 3 2.13598
MEFV Mediterranean fever 2.13409
RCVRN recoverin 2.13356
MMP3 matrix metallopeptidase 3 2.13344
DSG1 desmoglein 1 2.12946
NRBF2 nuclear receptor binding factor 2 2.12779
WBSCR27 Williams Beuren syndrome chromosome region 27 2.12489
TEX19 testis expressed 19 2.1246
FGF7 fibroblast growth factor 7 2.12368
ZNF580 zinc finger protein 580 2.12319
VASH2 vasohibin 2 2.12106
ZNF780B zinc finger protein 780B 2.12082
ELSPBP1 epididymal sperm binding protein 1 2.12074
UNC13A unc-13 homolog A (C. elegans) 2.1188
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 2.1176
PPP1R18 protein phosphatase 1, regulatory subunit 18 2.11628
RABL2A RAB, member of RAS oncogene family-like 2A 2.11481
ITLN1 intelectin 1 (galactofuranose binding) 2.11373
RNF165 ring finger protein 165 2.11172
COL5A1 collagen, type V, alpha 1 2.11167
TMEM126A transmembrane protein 126A 2.09709
ZSWIM4 zinc finger, SWIM-type containing 4 2.09356
PRSS8 protease, serine, 8 2.09128
CLCA2 chloride channel accessory 2 2.0879
NISCH nischarin 2.08751
DLX4 distal-less homeobox 4 2.08702
CMC2 C-x(9)-C motif containing 2 2.08538
PGLYRP2 peptidoglycan recognition protein 2 2.08372
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 2.08271
STC1 stanniocalcin 1 2.07914
SH3BP4 SH3-domain binding protein 4 2.07842
BIRC6 baculoviral IAP repeat containing 6 2.07804
GATSL3 GATS protein-like 3 2.07792
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 2.07663
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.07361
SH2D3A SH2 domain containing 3A 2.07349
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 2.07286
PCIF1 PDX1 C-terminal inhibiting factor 1 2.07156
HOXB9 homeobox B9 2.07127
PTCH1 patched 1 2.07003
DSC3 desmocollin 3 2.06504
TMEM38A transmembrane protein 38A 2.06453
FOXN2 forkhead box N2 2.06094
TTC22 tetratricopeptide repeat domain 22 2.0608
AK7 adenylate kinase 7 2.05891
LDLRAD1 low density lipoprotein receptor class A domain containing 1 2.05836
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 2.05786
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 2.05425
HOXC10 homeobox C10 2.05356
EML6 echinoderm microtubule associated protein like 6 2.05197
RANGRF RAN guanine nucleotide release factor 2.04809
SERTM1 serine-rich and transmembrane domain containing 1 2.04342
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.04253
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 2.04128
POC1A POC1 centriolar protein A 2.04116
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 2.04026
OPTC opticin 2.03873
FAM47E family with sequence similarity 47, member E 2.03733
PGLYRP1 peptidoglycan recognition protein 1 2.03465
SPINDOC spindlin interactor and repressor of chromatin binding 2.03251
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) 2.02635
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 2.02483
ALPK1 alpha-kinase 1 2.02418
AK3 adenylate kinase 3 2.02177
GUCY2C guanylate cyclase 2C 2.02118
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.0206
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.0203
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 2.0189
POU3F3 POU class 3 homeobox 3 2.01821
EPS8L3 EPS8-like 3 2.01672
FAIM Fas apoptotic inhibitory molecule 2.01633
MYH2 myosin, heavy chain 2, skeletal muscle, adult 2.01265
TRIM39 tripartite motif containing 39 2.0124
RFX8 RFX family member 8, lacking RFX DNA binding domain 2.01092
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.01088
CACUL1 CDK2-associated, cullin domain 1 2.01055
USP51 ubiquitin specific peptidase 51 2.00967
APH1A APH1A gamma secretase subunit 2.006
TMPRSS2 transmembrane protease, serine 2 2.00438
CCDC69 coiled-coil domain containing 69 2.00292
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.00234
ISYNA1 inositol-3-phosphate synthase 1 2.00049