TE9 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
Description A immortal human esophagus-derived cell line cell that has the characteristics: Human esophageal squamous cell carcinoma (poorly differentiated) cell line. Not transplantable to nude mouse. TKG0260 (Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051379)
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Genes

459 gene knockdowns changing fitness of TE9 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
MMP24 matrix metallopeptidase 24 (membrane-inserted) 3.14983
CD34 CD34 molecule 3.03156
PCDHB14 protocadherin beta 14 3.01263
MYLIP myosin regulatory light chain interacting protein 3.00202
ARF4 ADP-ribosylation factor 4 2.96606
KAT5 K(lysine) acetyltransferase 5 2.82617
BCAR3 breast cancer anti-estrogen resistance 3 2.62425
MAT2B methionine adenosyltransferase II, beta 2.61049
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2.56338
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 2.54705
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2.36561
FETUB fetuin B 2.27434
ZFAND3 zinc finger, AN1-type domain 3 2.22837
EWSR1 EWS RNA-binding protein 1 2.14273
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.13612
LOC100653162 2.12313
MED1 mediator complex subunit 1 2.11067
ZIK1 zinc finger protein interacting with K protein 1 2.10093
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 2.07353
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 2.07342
RNF25 ring finger protein 25 2.02056
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.01269
IL22 interleukin 22 1.98683
DLD dihydrolipoamide dehydrogenase 1.98446
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.9835
KCTD10 potassium channel tetramerization domain containing 10 1.98169
CHD5 chromodomain helicase DNA binding protein 5 1.95695
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 1.94087
GPR65 G protein-coupled receptor 65 1.93571
ANXA8 annexin A8 1.92927
ARSE arylsulfatase E (chondrodysplasia punctata 1) 1.8869
SRPK1 SRSF protein kinase 1 1.88193
ZCCHC13 zinc finger, CCHC domain containing 13 1.86677
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 1.85136
C19ORF48 chromosome 19 open reading frame 48 1.83577
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.8283
GJA1 gap junction protein, alpha 1, 43kDa 1.80413
FBXO18 F-box protein, helicase, 18 1.80211
TPTE transmembrane phosphatase with tensin homology 1.79639
SPRED2 sprouty-related, EVH1 domain containing 2 1.791
SMC2 structural maintenance of chromosomes 2 1.78637
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 1.78257
HMGN2 high mobility group nucleosomal binding domain 2 1.77978
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.7732
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.76751
TCEA3 transcription elongation factor A (SII), 3 1.76555
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.73935
RIMS3 regulating synaptic membrane exocytosis 3 1.69521
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.67877
RABIF RAB interacting factor 1.67088
DPYS dihydropyrimidinase 1.66061
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.65835
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 1.63486
SMAD2 SMAD family member 2 1.62447
HABP2 hyaluronan binding protein 2 1.60539
TRIM23 tripartite motif containing 23 1.5854
UBL3 ubiquitin-like 3 1.57834
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 1.5731
TSN translin 1.57133
STK38L serine/threonine kinase 38 like 1.55986
CLCN1 chloride channel, voltage-sensitive 1 1.54665
PCDHGB1 protocadherin gamma subfamily B, 1 1.5428
TSC22D3 TSC22 domain family, member 3 1.54142
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 1.53516
GPRC5C G protein-coupled receptor, class C, group 5, member C 1.53356
WNT1 wingless-type MMTV integration site family, member 1 1.53196
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 1.52887
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.5251
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.52308
RRM1 ribonucleotide reductase M1 1.51733
QDPR quinoid dihydropteridine reductase 1.51651
PPT1 palmitoyl-protein thioesterase 1 1.51189
MED17 mediator complex subunit 17 1.49952
NFYB nuclear transcription factor Y, beta 1.4982
UBC ubiquitin C 1.49428
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.49107
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 1.48912
TRPC7 transient receptor potential cation channel, subfamily C, member 7 1.47513
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 1.4717
H2BFM H2B histone family, member M 1.46954
INTS6 integrator complex subunit 6 1.4694
CLIC2 chloride intracellular channel 2 1.46137
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 1.45484
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.42073
RBBP6 retinoblastoma binding protein 6 1.41894
RNPS1 RNA binding protein S1, serine-rich domain 1.41787
ANKRD29 ankyrin repeat domain 29 1.41115
ANK2 ankyrin 2, neuronal 1.39913
EME1 essential meiotic structure-specific endonuclease 1 1.39685
ANXA8L1 annexin A8-like 1 1.39395
FABP1 fatty acid binding protein 1, liver 1.38815
DPRX divergent-paired related homeobox 1.38785
ERP44 endoplasmic reticulum protein 44 1.38458
IRX5 iroquois homeobox 5 1.38234
COPE coatomer protein complex, subunit epsilon 1.37957
ATP11A ATPase, class VI, type 11A 1.37795
MED19 mediator complex subunit 19 1.36885
PRICKLE1 prickle homolog 1 (Drosophila) 1.36427
MMP19 matrix metallopeptidase 19 1.36241
AFF1 AF4/FMR2 family, member 1 1.36113
ADCK5 aarF domain containing kinase 5 1.36062
TULP4 tubby like protein 4 1.35588
NCBP2 nuclear cap binding protein subunit 2, 20kDa 1.34733
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.33671
CNGA2 cyclic nucleotide gated channel alpha 2 1.33147
UFC1 ubiquitin-fold modifier conjugating enzyme 1 1.32966
CST3 cystatin C 1.329
OR4D1 olfactory receptor, family 4, subfamily D, member 1 1.32785
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 1.32638
GPR143 G protein-coupled receptor 143 1.32489
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.31955
KIAA1804 mixed lineage kinase 4 1.31941
CPB1 carboxypeptidase B1 (tissue) 1.31354
DGKA diacylglycerol kinase, alpha 80kDa 1.31219
PRKG2 protein kinase, cGMP-dependent, type II 1.3113
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 1.3038
VEZF1 vascular endothelial zinc finger 1 1.29644
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 1.29644
ODC1 ornithine decarboxylase 1 1.29227
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 1.28265
PARK2 parkin RBR E3 ubiquitin protein ligase 1.28104
BRI3 brain protein I3 1.26591
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.26579
TAOK1 TAO kinase 1 1.26041
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.25699
CRP C-reactive protein, pentraxin-related 1.25487
IL17C interleukin 17C 1.25417
PCDHA4 protocadherin alpha 4 1.25059
CPNE3 copine III 1.24554
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 1.24327
SLC26A9 solute carrier family 26 (anion exchanger), member 9 1.24308
AIRE autoimmune regulator 1.24305
NAPSA napsin A aspartic peptidase 1.242
PPARG peroxisome proliferator-activated receptor gamma 1.23933
MPPE1 metallophosphoesterase 1 1.23927
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.23682
RDH8 retinol dehydrogenase 8 (all-trans) 1.234
CCT2 chaperonin containing TCP1, subunit 2 (beta) 1.23005
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.22654
HNF1B HNF1 homeobox B 1.22631
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.22601
FAM3C family with sequence similarity 3, member C 1.21552
ZNF12 zinc finger protein 12 1.21295
RPTOR regulatory associated protein of MTOR, complex 1 1.20884
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.20777
STEAP3 STEAP family member 3, metalloreductase 1.20586
MAN2A1 mannosidase, alpha, class 2A, member 1 1.19613
OSR2 odd-skipped related transciption factor 2 1.18625
PDCL3 phosducin-like 3 1.18381
MVD mevalonate (diphospho) decarboxylase 1.18256
MST1R macrophage stimulating 1 receptor 1.18199
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.1808
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 1.17846
ZIC5 Zic family member 5 1.17804
BAG4 BCL2-associated athanogene 4 1.16803
ACR acrosin 1.16209
NPR2 natriuretic peptide receptor 2 1.15928
WARS tryptophanyl-tRNA synthetase 1.15237
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.15173
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3 1.14695
MLH1 mutL homolog 1 1.14616
RIC8B RIC8 guanine nucleotide exchange factor B 1.14567
KRT3 keratin 3, type II 1.14336
ATR ATR serine/threonine kinase 1.14032
MADD MAP-kinase activating death domain 1.13995
SSBP2 single-stranded DNA binding protein 2 1.1365
PPP1R16A protein phosphatase 1, regulatory subunit 16A 1.13595
ADK adenosine kinase 1.13498
CAMK1G calcium/calmodulin-dependent protein kinase IG 1.13478
BRWD1 bromodomain and WD repeat domain containing 1 1.12914
TESK2 testis-specific kinase 2 1.12814
KLF6 Kruppel-like factor 6 1.12232
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 1.12171
FFAR2 free fatty acid receptor 2 1.11342
AVIL advillin 1.1116
RCOR3 REST corepressor 3 1.1094
PRSS35 protease, serine, 35 1.10823
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 1.10682
PDCD1 programmed cell death 1 1.10576
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.10477
RAB17 RAB17, member RAS oncogene family 1.10329
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 1.09935
OIT3 oncoprotein induced transcript 3 1.09783
OR4D11 olfactory receptor, family 4, subfamily D, member 11 1.09183
DDIT4 DNA-damage-inducible transcript 4 1.09042
CDK4 cyclin-dependent kinase 4 1.08834
CCNT1 cyclin T1 1.08722
TIGD6 tigger transposable element derived 6 1.08719
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.08561
TRIP4 thyroid hormone receptor interactor 4 1.08315
KLF15 Kruppel-like factor 15 1.08275
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.0777
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1 1.07313
ULBP1 UL16 binding protein 1 1.07274
ZNF426 zinc finger protein 426 1.06909
SLC35B1 solute carrier family 35, member B1 1.06907
KDM1A lysine (K)-specific demethylase 1A 1.06342
PLAG1 pleiomorphic adenoma gene 1 1.06312
GH2 growth hormone 2 1.05815
FGFR3 fibroblast growth factor receptor 3 1.05756
ZFR zinc finger RNA binding protein 1.05705
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.05562
LDHA lactate dehydrogenase A 1.05555
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 1.05266
KNG1 kininogen 1 1.05261
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.05236
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.04901
RGS4 regulator of G-protein signaling 4 1.0484
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 1.04728
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.04622
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.04077
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.03915
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.03804
SREBF2 sterol regulatory element binding transcription factor 2 1.03503
EPHA6 EPH receptor A6 1.03411
CELA1 chymotrypsin-like elastase family, member 1 1.0307
SSBP4 single stranded DNA binding protein 4 1.02466
BRD2 bromodomain containing 2 1.02243
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.02067
LTB4R leukotriene B4 receptor 1.01996
PKD2L1 polycystic kidney disease 2-like 1 1.01724
HPR haptoglobin-related protein 1.01518
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene 1.01491
ACVR1 activin A receptor, type I 1.01349
IL12A interleukin 12A 1.01272
OR3A1 olfactory receptor, family 3, subfamily A, member 1 1.01193
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 1.01079
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.01072
NUP93 nucleoporin 93kDa 1.00556
PRSS36 protease, serine, 36 1.00498
HIST1H2BL histone cluster 1, H2bl 1.00466
RUVBL1 RuvB-like AAA ATPase 1 1.00356
HYAL1 hyaluronoglucosaminidase 1 1.00227

decreased fitness

Symbol Name Standardized Value
LUC7L LUC7-like (S. cerevisiae) -3.36769
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -2.76831
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -2.66638
RASL11B RAS-like, family 11, member B -2.54084
TAS2R42 taste receptor, type 2, member 42 -2.49046
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.464
PCDHA11 protocadherin alpha 11 -2.45492
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -2.35931
TRIM49 tripartite motif containing 49 -2.29241
CD300C CD300c molecule -2.28119
ZSCAN10 zinc finger and SCAN domain containing 10 -2.27565
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.23731
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -2.21568
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -2.19095
ZCCHC3 zinc finger, CCHC domain containing 3 -2.18639
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 -2.17479
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.03441
FZD4 frizzled class receptor 4 -2.01982
MMP28 matrix metallopeptidase 28 -1.98106
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -1.98011
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -1.97724
FBN2 fibrillin 2 -1.9662
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -1.91758
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -1.88992
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -1.87053
GTF2IRD1 GTF2I repeat domain containing 1 -1.85882
IL25 interleukin 25 -1.84602
MPL MPL proto-oncogene, thrombopoietin receptor -1.84003
SCARA3 scavenger receptor class A, member 3 -1.81131
TMX3 thioredoxin-related transmembrane protein 3 -1.7901
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -1.77625
RPP38 ribonuclease P/MRP 38kDa subunit -1.77537
BRMS1 breast cancer metastasis suppressor 1 -1.75073
ADAR adenosine deaminase, RNA-specific -1.7408
EFNB2 ephrin-B2 -1.72981
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -1.7241
KIF13B kinesin family member 13B -1.72333
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) -1.72327
PRKDC protein kinase, DNA-activated, catalytic polypeptide -1.7058
ANTXR2 anthrax toxin receptor 2 -1.69302
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 -1.68833
AKR1D1 aldo-keto reductase family 1, member D1 -1.68696
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -1.66879
CPN1 carboxypeptidase N, polypeptide 1 -1.66735
CD59 CD59 molecule, complement regulatory protein -1.65287
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -1.64745
HTRA4 HtrA serine peptidase 4 -1.62247
ANTXR1 anthrax toxin receptor 1 -1.62052
RNMTL1 RNA methyltransferase like 1 -1.60776
ADAM17 ADAM metallopeptidase domain 17 -1.59485
GCKR glucokinase (hexokinase 4) regulator -1.59436
SECISBP2L SECIS binding protein 2-like -1.59371
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -1.59352
NME5 NME/NM23 family member 5 -1.58458
SYCP2L synaptonemal complex protein 2-like -1.58427
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 -1.57953
TLX1 T-cell leukemia homeobox 1 -1.57938
GYS1 glycogen synthase 1 (muscle) -1.57382
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -1.55807
FZD3 frizzled class receptor 3 -1.5446
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -1.54102
MOCS3 molybdenum cofactor synthesis 3 -1.53682
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -1.52208
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -1.51479
PRKACG protein kinase, cAMP-dependent, catalytic, gamma -1.50883
TRAIP TRAF interacting protein -1.50872
TSC1 tuberous sclerosis 1 -1.5009
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -1.48771
RRAGB Ras-related GTP binding B -1.4825
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.46912
CDK10 cyclin-dependent kinase 10 -1.46424
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -1.46274
PNPLA6 patatin-like phospholipase domain containing 6 -1.46137
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -1.45993
SHOX2 short stature homeobox 2 -1.44619
S1PR5 sphingosine-1-phosphate receptor 5 -1.43854
CNGA3 cyclic nucleotide gated channel alpha 3 -1.43374
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 -1.42861
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -1.42803
ANKFY1 ankyrin repeat and FYVE domain containing 1 -1.4247
OR52L1 olfactory receptor, family 52, subfamily L, member 1 -1.42421
ADD1 adducin 1 (alpha) -1.4238
HCAR1 hydroxycarboxylic acid receptor 1 -1.4201
SOS1 son of sevenless homolog 1 (Drosophila) -1.41893
ADGRE1 adhesion G protein-coupled receptor E1 -1.41854
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit -1.41727
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -1.41328
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -1.41106
ZNF791 zinc finger protein 791 -1.41054
EXOSC1 exosome component 1 -1.40793
TIMP3 TIMP metallopeptidase inhibitor 3 -1.40407
DLK2 delta-like 2 homolog (Drosophila) -1.40055
RNF183 ring finger protein 183 -1.40052
TRPV3 transient receptor potential cation channel, subfamily V, member 3 -1.39382
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A -1.39296
MSC musculin -1.38594
NR1I2 nuclear receptor subfamily 1, group I, member 2 -1.38542
SP7 Sp7 transcription factor -1.3761
XRN2 5'-3' exoribonuclease 2 -1.37537
BHLHE22 basic helix-loop-helix family, member e22 -1.3753
OR2T12 olfactory receptor, family 2, subfamily T, member 12 -1.37519
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -1.36657
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 -1.36347
ANXA7 annexin A7 -1.36332
SOCS6 suppressor of cytokine signaling 6 -1.35929
ST13P4 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4 -1.35796
CYB561 cytochrome b561 -1.35694
MLKL mixed lineage kinase domain-like -1.3553
NT5M 5',3'-nucleotidase, mitochondrial -1.34782
NTAN1 N-terminal asparagine amidase -1.34475
IGFBP6 insulin-like growth factor binding protein 6 -1.34304
SIRT4 sirtuin 4 -1.33786
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -1.33727
TRIP6 thyroid hormone receptor interactor 6 -1.33718
NR1H3 nuclear receptor subfamily 1, group H, member 3 -1.32146
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase -1.3196
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 -1.31402
CAMKV CaM kinase-like vesicle-associated -1.31046
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -1.30795
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -1.30593
OR7G2 olfactory receptor, family 7, subfamily G, member 2 -1.30535
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.29984
NUAK1 NUAK family, SNF1-like kinase, 1 -1.29118
MMP23B matrix metallopeptidase 23B -1.27985
DEGS2 delta(4)-desaturase, sphingolipid 2 -1.2791
SLC35A4 solute carrier family 35, member A4 -1.27649
LMBR1 limb development membrane protein 1 -1.26547
NUCB1 nucleobindin 1 -1.26545
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -1.26335
AUP1 ancient ubiquitous protein 1 -1.26277
ZFP64 ZFP64 zinc finger protein -1.25954
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -1.25899
MT1F metallothionein 1F -1.25888
LOC729739 peptidylprolyl isomerase A (cyclophilin A) pseudogene -1.25369
ATF7 activating transcription factor 7 -1.25365
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -1.25011
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 -1.25001
HIST1H4E histone cluster 1, H4e -1.24731
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -1.24016
AOX1 aldehyde oxidase 1 -1.23858
PLRG1 pleiotropic regulator 1 -1.23798
SYTL2 synaptotagmin-like 2 -1.23558
PRPF3 pre-mRNA processing factor 3 -1.22897
WDR11 WD repeat domain 11 -1.22709
KLK4 kallikrein-related peptidase 4 -1.22617
ZSCAN20 zinc finger and SCAN domain containing 20 -1.21818
MMP27 matrix metallopeptidase 27 -1.21767
FGF3 fibroblast growth factor 3 -1.21738
GPR151 G protein-coupled receptor 151 -1.21433
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -1.21006
ZNF239 zinc finger protein 239 -1.20664
USP34 ubiquitin specific peptidase 34 -1.19986
STRN striatin, calmodulin binding protein -1.19806
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -1.18832
SV2B synaptic vesicle glycoprotein 2B -1.18593
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -1.18485
CIC capicua transcriptional repressor -1.17901
PARP10 poly (ADP-ribose) polymerase family, member 10 -1.17413
TP53 tumor protein p53 -1.17193
BCAP29 B-cell receptor-associated protein 29 -1.17183
PUF60 poly-U binding splicing factor 60KDa -1.17098
ATXN7 ataxin 7 -1.1627
KRT4 keratin 4, type II -1.15925
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.15919
LIPE lipase, hormone-sensitive -1.15735
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) -1.15387
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -1.15038
GHSR growth hormone secretagogue receptor -1.1495
NR2F6 nuclear receptor subfamily 2, group F, member 6 -1.14736
MCHR1 melanin-concentrating hormone receptor 1 -1.14648
CABP5 calcium binding protein 5 -1.14049
SPTAN1 spectrin, alpha, non-erythrocytic 1 -1.13383
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 -1.13256
CELF2 CUGBP, Elav-like family member 2 -1.13109
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 -1.1309
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.12671
ARL3 ADP-ribosylation factor-like 3 -1.12553
GOPC golgi-associated PDZ and coiled-coil motif containing -1.12549
ITPK1 inositol-tetrakisphosphate 1-kinase -1.12357
RFX2 regulatory factor X, 2 (influences HLA class II expression) -1.12222
KLF10 Kruppel-like factor 10 -1.11981
NPC2 Niemann-Pick disease, type C2 -1.11973
GLP2R glucagon-like peptide 2 receptor -1.11807
SEC13 SEC13 homolog (S. cerevisiae) -1.10767
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -1.10751
DGKQ diacylglycerol kinase, theta 110kDa -1.10543
CASP7 caspase 7, apoptosis-related cysteine peptidase -1.10032
CXCL10 chemokine (C-X-C motif) ligand 10 -1.10017
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -1.0978
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -1.09481
BST2 bone marrow stromal cell antigen 2 -1.09111
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -1.09036
TRIM17 tripartite motif containing 17 -1.09026
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -1.08576
RAB11A RAB11A, member RAS oncogene family -1.08252
SYT4 synaptotagmin IV -1.08016
HIST1H3G histone cluster 1, H3g -1.07787
P3H2 prolyl 3-hydroxylase 2 -1.0692
DRD2 dopamine receptor D2 -1.06711
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 -1.067
TPSD1 tryptase delta 1 -1.06682
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 -1.06632
HRK harakiri, BCL2 interacting protein -1.05387
EXOSC2 exosome component 2 -1.05253
C5 complement component 5 -1.05241
NPTXR neuronal pentraxin receptor -1.05237
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 -1.04802
NME1-NME2 NME1-NME2 readthrough -1.04586
PCLO piccolo presynaptic cytomatrix protein -1.03988
CTSC cathepsin C -1.03868
PMPCA peptidase (mitochondrial processing) alpha -1.03525
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -1.03498
TGIF1 TGFB-induced factor homeobox 1 -1.03394
ACAA1 acetyl-CoA acyltransferase 1 -1.03352
POFUT2 protein O-fucosyltransferase 2 -1.03171
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -1.02903
POU1F1 POU class 1 homeobox 1 -1.0285
ACTN4 actinin, alpha 4 -1.02648
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -1.01921
MMP23A matrix metallopeptidase 23A (pseudogene) -1.01069
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -1.00524
SLA2 Src-like-adaptor 2 -1.00456
MRRF mitochondrial ribosome recycling factor -1.0029
PRKG1 protein kinase, cGMP-dependent, type I -1.00253
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -1.00197
ZNF362 zinc finger protein 362 -1.00117