TEAD1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description TEA domain family member 1 (SV40 transcriptional enhancer factor)|This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 7003)
External Link https://ncbi.nlm.nih.gov/gene/7003
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Genes

500 genes differentially expressed following the TEAD1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0140567
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0133243
AQP3 aquaporin 3 (Gill blood group) 0.0126497
IFI27 interferon, alpha-inducible protein 27 0.0113947
PDZK1IP1 PDZK1 interacting protein 1 0.0113906
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0112326
LCN2 lipocalin 2 0.010488
MGLL monoglyceride lipase 0.0102858
MX1 MX dynamin-like GTPase 1 0.0102399
S100A9 S100 calcium binding protein A9 0.0100239
CRYAB crystallin, alpha B 0.00997587
TACSTD2 tumor-associated calcium signal transducer 2 0.00942231
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00938991
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00936457
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0092622
IFI44L interferon-induced protein 44-like 0.00912399
SNX11 sorting nexin 11 0.00908514
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00902185
TRIP6 thyroid hormone receptor interactor 6 0.00877227
MT1X metallothionein 1X 0.00876006
ZYX zyxin 0.00867897
HSPB8 heat shock 22kDa protein 8 0.00865886
ASS1 argininosuccinate synthase 1 0.00848689
GRB7 growth factor receptor-bound protein 7 0.00847038
METTL7A methyltransferase like 7A 0.00844358
CA2 carbonic anhydrase II 0.00816265
S100A7 S100 calcium binding protein A7 0.0081497
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00809953
SLPI secretory leukocyte peptidase inhibitor 0.00806293
IPO13 importin 13 0.00800227
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00795364
HSPA1A heat shock 70kDa protein 1A 0.00790729
APOD apolipoprotein D 0.00782501
CSTA cystatin A (stefin A) 0.007825
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00780375
DEFB1 defensin, beta 1 0.00774108
MVP major vault protein 0.00765399
IL1RN interleukin 1 receptor antagonist 0.00764309
TUBB2A tubulin, beta 2A class IIa 0.00762332
S100A11 S100 calcium binding protein A11 0.00759192
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00758808
MT1H metallothionein 1H 0.00755701
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00743205
QPRT quinolinate phosphoribosyltransferase 0.00742487
IFI6 interferon, alpha-inducible protein 6 0.00742176
ATF3 activating transcription factor 3 0.00737677
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00737129
SNAP25 synaptosomal-associated protein, 25kDa 0.00736487
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00736477
SPRR2B small proline-rich protein 2B 0.00735144
SASH1 SAM and SH3 domain containing 1 0.00726255
KLK10 kallikrein-related peptidase 10 0.00724783
TRIM22 tripartite motif containing 22 0.00717382
MTA1 metastasis associated 1 0.0071535
PCSK5 proprotein convertase subtilisin/kexin type 5 0.00714278
ACTN4 actinin, alpha 4 0.00713964
JPT1 Jupiter microtubule associated homolog 1 0.00710795
MAST4 microtubule associated serine/threonine kinase family member 4 0.00709767
HIST1H2AC histone cluster 1, H2ac 0.00707943
SPRR3 small proline-rich protein 3 0.00704802
INAVA innate immunity activator 0.00699497
HIP1R huntingtin interacting protein 1 related 0.0069824
KRT6A keratin 6A, type II 0.00696474
MINK1 misshapen-like kinase 1 0.00696077
PELI1 pellino E3 ubiquitin protein ligase 1 0.00694729
ISG15 ISG15 ubiquitin-like modifier 0.00694048
ITM2C integral membrane protein 2C 0.00692215
SIRPA signal-regulatory protein alpha 0.0069134
SFRP1 secreted frizzled-related protein 1 0.00688349
TGFBR3 transforming growth factor, beta receptor III 0.00688217
MT1HL1 metallothionein 1H-like 1 0.00687108
PPL periplakin 0.00686082
CXCL14 chemokine (C-X-C motif) ligand 14 0.00681546
BEX1 brain expressed, X-linked 1 0.00681277
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00679603
JUP junction plakoglobin 0.00674839
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00673943
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00670221
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.006681
TGFA transforming growth factor, alpha 0.00667653
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00665954
DAXX death-domain associated protein 0.00662689
SYNGR3 synaptogyrin 3 0.00659885
TPPP3 tubulin polymerization-promoting protein family member 3 0.00658822
PYCARD PYD and CARD domain containing 0.00657308
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00656196
STX4 syntaxin 4 0.00655657
ACADVL acyl-CoA dehydrogenase, very long chain 0.00653588
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00650564
MDK midkine (neurite growth-promoting factor 2) 0.00650302
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00649853
CHGB chromogranin B 0.00648403
OPHN1 oligophrenin 1 0.00646989
RBM47 RNA binding motif protein 47 0.00646237
KRT15 keratin 15, type I 0.00645558
GSTP1 glutathione S-transferase pi 1 0.00644699
MT1G metallothionein 1G 0.00643986
SPRR1A small proline-rich protein 1A 0.00643669
IFITM1 interferon induced transmembrane protein 1 0.0064283
PLXNB2 plexin B2 0.00642337
IRF7 interferon regulatory factor 7 0.00638355
SPRR1B small proline-rich protein 1B 0.00634093
HEPH hephaestin 0.00630372
RNF19B ring finger protein 19B 0.00628995
PUF60 poly-U binding splicing factor 60KDa 0.0062872
GAB2 GRB2-associated binding protein 2 0.00628062
VSNL1 visinin-like 1 0.0062722
DHCR24 24-dehydrocholesterol reductase 0.00626939
LAMP5 lysosomal-associated membrane protein family, member 5 0.00622944
SPON1 spondin 1, extracellular matrix protein 0.006225
GUCY2C guanylate cyclase 2C 0.0062233
LY6D lymphocyte antigen 6 complex, locus D 0.00622226
ASXL2 additional sex combs like transcriptional regulator 2 0.00618899
AQP1 aquaporin 1 (Colton blood group) 0.00618223
S100A8 S100 calcium binding protein A8 0.00617934
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00617837
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00617695
TSPAN8 tetraspanin 8 0.00616332
MAPK13 mitogen-activated protein kinase 13 0.00614563
BHLHE41 basic helix-loop-helix family, member e41 0.00614158
BCL3 B-cell CLL/lymphoma 3 0.0061159
SLC22A18 solute carrier family 22, member 18 0.00611248
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00608965
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00608752
BAMBI BMP and activin membrane-bound inhibitor 0.0060836
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00605465
PRSS8 protease, serine, 8 0.00604674
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00603993
IER5 immediate early response 5 0.00602828
HSPB1 heat shock 27kDa protein 1 0.00601661
TFPI2 tissue factor pathway inhibitor 2 0.00600976
CLCA4 chloride channel accessory 4 0.00599845
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00599476
SCPEP1 serine carboxypeptidase 1 0.00598361
GALC galactosylceramidase 0.0059589
XAF1 XIAP associated factor 1 0.00595304
DSG3 desmoglein 3 0.0059239
GSTK1 glutathione S-transferase kappa 1 0.0059155
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.00588509
MT1F metallothionein 1F 0.0058838
SEPP1 selenoprotein P, plasma, 1 0.00587316
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00587163
MT2A metallothionein 2A 0.00584777
TSC22D4 TSC22 domain family, member 4 0.00583609
KRT13 keratin 13, type I 0.00581986
CLTB clathrin, light chain B 0.00581194
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00578356
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0057564
CXCL8 chemokine (C-X-C motif) ligand 8 0.00575488
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00574998
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00574689
BTG2 BTG family, member 2 0.00573962
KRT6B keratin 6B, type II 0.00573743
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00573604
LAT2 linker for activation of T cells family, member 2 0.00572502
TSPAN1 tetraspanin 1 0.00571073
KLK6 kallikrein-related peptidase 6 0.00570527
FDXR ferredoxin reductase 0.00569901
RSAD2 radical S-adenosyl methionine domain containing 2 0.00569807
KLK11 kallikrein-related peptidase 11 0.00567693
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00567647
EHD3 EH-domain containing 3 0.00566902
PLAAT3 phospholipase A and acyltransferase 3 0.00566212
TUBA4A tubulin, alpha 4a 0.00564171
TGM1 transglutaminase 1 0.00562991
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.0055831
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00558213
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00558142
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00557041
TRIB2 tribbles pseudokinase 2 0.00556159
FXYD3 FXYD domain containing ion transport regulator 3 0.0055612
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.00555469
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00555152
NPY1R neuropeptide Y receptor Y1 0.00553182
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00552134
FSCN1 fascin actin-bundling protein 1 0.00551267
EPS8L1 EPS8-like 1 0.0054973
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00549146
IRF9 interferon regulatory factor 9 0.00548602
FILIP1L filamin A interacting protein 1-like 0.00548353
ZNF185 zinc finger protein 185 (LIM domain) 0.00548059
CRNN cornulin 0.0054667
RRAD Ras-related associated with diabetes 0.00546351
PI3 peptidase inhibitor 3, skin-derived 0.00544359
AOC1 amine oxidase, copper containing 1 0.00542531
MT1E metallothionein 1E 0.00542235
PRR14 proline rich 14 0.00542019
DTX4 deltex 4, E3 ubiquitin ligase 0.00541006
MKRN1 makorin ring finger protein 1 0.00538739
MX2 MX dynamin-like GTPase 2 0.00538203
KRT19 keratin 19, type I 0.00535411
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.00534983
LYPD3 LY6/PLAUR domain containing 3 0.00533346
RTN2 reticulon 2 0.00532077
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00530476
CLCA2 chloride channel accessory 2 0.00530362
IRF4 interferon regulatory factor 4 0.00529655
FAXDC2 fatty acid hydroxylase domain containing 2 0.00529489
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00529387
S100A14 S100 calcium binding protein A14 0.00527291
DUSP5 dual specificity phosphatase 5 0.00527107
RAB9A RAB9A, member RAS oncogene family 0.00525485
SELENBP1 selenium binding protein 1 0.00523002
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 0.00522248
CRABP2 cellular retinoic acid binding protein 2 0.00521721
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.00521224
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00521168
CPM carboxypeptidase M 0.00520403
RET ret proto-oncogene 0.00520038
HBP1 HMG-box transcription factor 1 0.00518413
SMOX spermine oxidase 0.0051626
IL17RB interleukin 17 receptor B 0.0051486
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.00514623
SPON2 spondin 2, extracellular matrix protein 0.00513337
OASL 2'-5'-oligoadenylate synthetase-like 0.0051245
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00511791
MUC4 mucin 4, cell surface associated 0.00510499
RGS5 regulator of G-protein signaling 5 0.00510019
ESYT1 extended synaptotagmin-like protein 1 0.00509249
TUFM Tu translation elongation factor, mitochondrial 0.00509093
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.00508295
C14ORF132 chromosome 14 open reading frame 132 0.00507541
RUNX3 runt-related transcription factor 3 0.00506549
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00506392
CFB complement factor B 0.0050637
TUBB2B tubulin, beta 2B class IIb 0.0050625
AGTR1 angiotensin II receptor, type 1 0.00506109
ATP10B ATPase, class V, type 10B 0.00506085
CFD complement factor D (adipsin) 0.00505943
MISP mitotic spindle positioning 0.0050518
AGRN agrin 0.00504693
CCNG2 cyclin G2 0.00504313
ISG20 interferon stimulated exonuclease gene 20kDa 0.00504051
SPATA20 spermatogenesis associated 20 0.0050303
G0S2 G0/G1 switch 2 0.00502717
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00502458
NPEPL1 aminopeptidase-like 1 0.00499855
PLEK pleckstrin 0.00497854
HIST1H2BD histone cluster 1, H2bd 0.0049746
CCND2 cyclin D2 0.00497074
HOPX HOP homeobox 0.0049664
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0049436
TMEM176B transmembrane protein 176B 0.00494319
FRMD4B FERM domain containing 4B 0.00493943
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00493842
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00493573
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00493339
TP53 tumor protein p53 0.0049333
SCD5 stearoyl-CoA desaturase 5 0.00493187
MAP7D1 MAP7 domain containing 1 0.00493043

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0129855
RPS5 ribosomal protein S5 -0.0108205
RAD23B RAD23 homolog B (S. cerevisiae) -0.0101888
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0094482
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00943302
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00939761
CD52 CD52 molecule -0.0092586
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00878604
MRPS16 mitochondrial ribosomal protein S16 -0.00841117
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00838365
GSAP gamma-secretase activating protein -0.00758486
PDGFC platelet derived growth factor C -0.00757827
IL13RA2 interleukin 13 receptor, alpha 2 -0.00733108
CHEK2 checkpoint kinase 2 -0.00732385
SLC38A1 solute carrier family 38, member 1 -0.00716125
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -0.00712918
ODC1 ornithine decarboxylase 1 -0.00712397
PDIA3 protein disulfide isomerase family A, member 3 -0.00712227
DPYD dihydropyrimidine dehydrogenase -0.0071205
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00704155
CD69 CD69 molecule -0.0069616
TMEM14B transmembrane protein 14B -0.00688646
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00688084
USP1 ubiquitin specific peptidase 1 -0.00682679
GARS1 glycyl-tRNA synthetase 1 -0.0067798
NSL1 NSL1, MIS12 kinetochore complex component -0.00675286
CPVL carboxypeptidase, vitellogenic-like -0.006682
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.0066291
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00661945
CD1E CD1e molecule -0.00649461
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00648652
CCNA2 cyclin A2 -0.00648324
TMSB15A thymosin beta 15a -0.0064126
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.00640512
IGFBP1 insulin-like growth factor binding protein 1 -0.00634631
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.0063416
INTS6 integrator complex subunit 6 -0.00633987
LOXL2 lysyl oxidase-like 2 -0.00631524
MAP7 microtubule-associated protein 7 -0.00631032
MCTP1 multiple C2 domains, transmembrane 1 -0.0062731
ESD esterase D -0.0062674
THAP12 THAP domain containing 12 -0.00622993
DUT deoxyuridine triphosphatase -0.00620339
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00618414
GANAB glucosidase, alpha; neutral AB -0.00617526
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00616791
CDCA4 cell division cycle associated 4 -0.00609531
CCDC47 coiled-coil domain containing 47 -0.00607808
LUM lumican -0.00606759
SNX7 sorting nexin 7 -0.00602724
OIP5 Opa interacting protein 5 -0.00596503
TIPRL TOR signaling pathway regulator -0.00596028
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.00593909
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00593269
SPC25 SPC25, NDC80 kinetochore complex component -0.00588936
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00587128
SLC38A4 solute carrier family 38, member 4 -0.00583761
NEK2 NIMA-related kinase 2 -0.00582786
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00582635
AURKB aurora kinase B -0.00580794
C12ORF29 chromosome 12 open reading frame 29 -0.00579558
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00579506
DRG1 developmentally regulated GTP binding protein 1 -0.005787
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00578617
TMEM106B transmembrane protein 106B -0.00576026
CPB2 carboxypeptidase B2 (plasma) -0.00573668
YME1L1 YME1-like 1 ATPase -0.00568252
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00565884
SULF1 sulfatase 1 -0.00565095
TAGLN2 transgelin 2 -0.00564289
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00560705
ENSA endosulfine alpha -0.00559624
KIF20A kinesin family member 20A -0.00559055
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00555314
NNMT nicotinamide N-methyltransferase -0.00553741
EPHA4 EPH receptor A4 -0.00553132
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00552603
COPS4 COP9 signalosome subunit 4 -0.00550676
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00549748
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -0.00544499
F5 coagulation factor V (proaccelerin, labile factor) -0.00542768
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.00541673
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00540327
PCLO piccolo presynaptic cytomatrix protein -0.00538214
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00536186
ISOC1 isochorismatase domain containing 1 -0.00535196
DBF4 DBF4 zinc finger -0.00534476
AGO3 argonaute RISC catalytic component 3 -0.00534069
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00533507
RPL29 ribosomal protein L29 -0.0053175
SRSF1 serine/arginine-rich splicing factor 1 -0.00528074
NKX3-1 NK3 homeobox 1 -0.00525619
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00524568
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -0.00522902
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -0.00522299
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00522072
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00521927
RPP30 ribonuclease P/MRP 30kDa subunit -0.00521876
SOX11 SRY (sex determining region Y)-box 11 -0.00521474
PARPBP PARP1 binding protein -0.00521301
CLEC2B C-type lectin domain family 2, member B -0.00519789
SPIN1 spindlin 1 -0.00519767
CDH13 cadherin 13 -0.0051891
RAD51 RAD51 recombinase -0.00518508
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00517095
VCAM1 vascular cell adhesion molecule 1 -0.00516306
ANGEL2 angel homolog 2 (Drosophila) -0.0051612
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00515841
HMGN4 high mobility group nucleosomal binding domain 4 -0.00514792
TRAPPC4 trafficking protein particle complex 4 -0.00514438
EIF3L eukaryotic translation initiation factor 3, subunit L -0.00512665
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00512348
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00511975
RNASEH2B ribonuclease H2, subunit B -0.00511527
SETMAR SET domain and mariner transposase fusion gene -0.005112
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00509947
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.00508581
TATDN2 TatD DNase domain containing 2 -0.00507722
CDC25C cell division cycle 25C -0.00507201
APOC3 apolipoprotein C-III -0.00506241
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00506128
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00504165
GPN3 GPN-loop GTPase 3 -0.00502868
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00502499
FASTKD3 FAST kinase domains 3 -0.0050157
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00501328
FAM172A family with sequence similarity 172, member A -0.00500655
FBXO11 F-box protein 11 -0.00500451
CLGN calmegin -0.0049897
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00498889
WIF1 WNT inhibitory factor 1 -0.00498514
COMMD8 COMM domain containing 8 -0.00498424
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -0.00497434
HMGB2 high mobility group box 2 -0.00493265
PRKCA protein kinase C, alpha -0.00493188
TMEM38B transmembrane protein 38B -0.00492447
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00491436
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -0.00490865
NUP37 nucleoporin 37kDa -0.00490271
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.00490131
TMEM165 transmembrane protein 165 -0.00489532
KLHL23 kelch-like family member 23 -0.00489405
ZWILCH zwilch kinetochore protein -0.00488889
UBL3 ubiquitin-like 3 -0.00487475
CEP55 centrosomal protein 55kDa -0.00485316
PRR16 proline rich 16 -0.00483876
TFAM transcription factor A, mitochondrial -0.00483726
ABHD10 abhydrolase domain containing 10 -0.00481697
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00478956
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -0.00478903
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00478373
C9 complement component 9 -0.00477956
PRMT1 protein arginine methyltransferase 1 -0.00477018
CDC6 cell division cycle 6 -0.00476775
ELOVL6 ELOVL fatty acid elongase 6 -0.00476523
MCMBP minichromosome maintenance complex binding protein -0.00476501
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00476016
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00475991
RAD51C RAD51 paralog C -0.00475805
MOCS2 molybdenum cofactor synthesis 2 -0.00475573
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.00473721
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00473166
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00472751
MRPL9 mitochondrial ribosomal protein L9 -0.00472284
ICE2 interactor of little elongation complex ELL subunit 2 -0.00470983
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00469786
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00469756
OXSM 3-oxoacyl-ACP synthase, mitochondrial -0.00469321
CDKN3 cyclin-dependent kinase inhibitor 3 -0.0046876
OSBPL8 oxysterol binding protein-like 8 -0.00468544
TMX1 thioredoxin-related transmembrane protein 1 -0.00468124
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00467623
GPR88 G protein-coupled receptor 88 -0.00467111
CHPT1 choline phosphotransferase 1 -0.00467007
DSCC1 DNA replication and sister chromatid cohesion 1 -0.00464359
SEC23A Sec23 homolog A (S. cerevisiae) -0.00464258
PTER phosphotriesterase related -0.00462555
PBK PDZ binding kinase -0.00462541
ERH enhancer of rudimentary homolog (Drosophila) -0.00462508
ANXA10 annexin A10 -0.00462286
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.00461394
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -0.00460922
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -0.00460904
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00460804
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -0.00460695
TIPIN TIMELESS interacting protein -0.00460234
MTREX Mtr4 exosome RNA helicase -0.00460007
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -0.00459693
LTA4H leukotriene A4 hydrolase -0.00459164
CPD carboxypeptidase D -0.00459102
ANKRD49 ankyrin repeat domain 49 -0.00458756
MRPL36 mitochondrial ribosomal protein L36 -0.00458684
MAPK1 mitogen-activated protein kinase 1 -0.00457687
AP1AR adaptor-related protein complex 1 associated regulatory protein -0.00456968
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -0.00456763
ZNF22 zinc finger protein 22 -0.00455208
TRA2B transformer 2 beta homolog (Drosophila) -0.00455187
FASTKD1 FAST kinase domains 1 -0.00454993
TLR4 toll-like receptor 4 -0.00454861
PRPF4 pre-mRNA processing factor 4 -0.00454808
ORC5 origin recognition complex, subunit 5 -0.00454346
PUM2 pumilio RNA-binding family member 2 -0.00454146
ADGRG6 adhesion G protein-coupled receptor G6 -0.00454065
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -0.00453653
IARS1 isoleucyl-tRNA synthetase 1 -0.00453463
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00453426
CHMP3 charged multivesicular body protein 3 -0.00453415
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -0.00452361
TKTL1 transketolase-like 1 -0.00452098
PLPBP pyridoxal phosphate binding protein -0.00451769
ATP5MG ATP synthase membrane subunit g -0.0045093
CHEK1 checkpoint kinase 1 -0.00450696
TOX thymocyte selection-associated high mobility group box -0.00448898
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -0.00448158
PHYH phytanoyl-CoA 2-hydroxylase -0.00447265
CDK13 cyclin-dependent kinase 13 -0.00445903
THYN1 thymocyte nuclear protein 1 -0.00445498
PRELID3B PRELI domain containing 3B -0.00443936
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00443845
ANO1 anoctamin 1, calcium activated chloride channel -0.0044287
RAD17 RAD17 homolog (S. pombe) -0.00442635
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00441957
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -0.00441497
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00441249
ALCAM activated leukocyte cell adhesion molecule -0.00440179
ACP6 acid phosphatase 6, lysophosphatidic -0.00439971
ATF1 activating transcription factor 1 -0.00439229
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.00439169
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -0.00439096
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00439093
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -0.00437963
ZIC1 Zic family member 1 -0.00437407
ARPP21 cAMP-regulated phosphoprotein, 21kDa -0.00436642
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -0.00436163
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00436138
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00435996
PDAP1 PDGFA associated protein 1 -0.00435164
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -0.00434827
C1ORF112 chromosome 1 open reading frame 112 -0.00434721
FBXO5 F-box protein 5 -0.00434396
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00434337
ARL4A ADP-ribosylation factor-like 4A -0.00433564
SERF2 small EDRK-rich factor 2 -0.00432214
ACTL6A actin-like 6A -0.00430918
ATRAID all-trans retinoic acid-induced differentiation factor -0.00430751
MRPL35 mitochondrial ribosomal protein L35 -0.00430494
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00430354
CRP C-reactive protein, pentraxin-related -0.00429792
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -0.00429007
PLK4 polo-like kinase 4 -0.00428794