TEAD4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description TEA domain family member 4|This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7004)
Similar Terms
Downloads & Tools

Genes

321 genes differentially expressed following the TEAD4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ACTL10 actin-like 10 3.8759
ZIC4 Zic family member 4 3.8759
APOL6 apolipoprotein L, 6 3.8759
ENTHD1 ENTH domain containing 1 3.8759
MYBPHL myosin binding protein H-like 3.8759
LYZL4 lysozyme-like 4 3.8759
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 3.8759
PCDHB6 protocadherin beta 6 3.8759
GPRC5A G protein-coupled receptor, class C, group 5, member A 3.8759
LAMP3 lysosomal-associated membrane protein 3 3.8759
IHO1 interactor of HORMAD1 1 3.8759
FRK fyn-related Src family tyrosine kinase 3.8759
LMX1A LIM homeobox transcription factor 1, alpha 3.8759
CIROZ ciliated left-right organizer protein containing ZP-N domains 3.8759
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.8759
C22ORF42 chromosome 22 open reading frame 42 3.8759
PCDHGA3 protocadherin gamma subfamily A, 3 3.8759
H3C14 H3 clustered histone 14 3.8759
COX8C cytochrome c oxidase subunit VIIIC 3.8759
SSTR1 somatostatin receptor 1 3.8169
NCF1 neutrophil cytosolic factor 1 3.8169
HES5 hes family bHLH transcription factor 5 3.8169
FGL2 fibrinogen-like 2 3.8169
ERAS ES cell expressed Ras 3.8169
RAET1G retinoic acid early transcript 1G 3.8169
CD6 CD6 molecule 3.8169
PGLYRP2 peptidoglycan recognition protein 2 3.8169
GPR52 G protein-coupled receptor 52 3.8169
IGFL3 IGF-like family member 3 3.8169
PRICKLE4 prickle homolog 4 (Drosophila) 3.8169
CAMP cathelicidin antimicrobial peptide 3.8169
PTGFR prostaglandin F receptor (FP) 3.8169
PNMA5 paraneoplastic Ma antigen family member 5 3.8169
S100A1 S100 calcium binding protein A1 3.8169
COL15A1 collagen, type XV, alpha 1 3.8169
OR5V1 olfactory receptor, family 5, subfamily V, member 1 3.8169
MUC22 mucin 22 3.8169
CRYGA crystallin, gamma A 3.8169
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 3.8169
TAS2R19 taste receptor, type 2, member 19 3.8169
TBC1D3 TBC1 domain family, member 3 3.8169
GNG13 guanine nucleotide binding protein (G protein), gamma 13 3.8169
COPZ2 coatomer protein complex, subunit zeta 2 3.8169
CXORF65 chromosome X open reading frame 65 3.8169
BMP8A bone morphogenetic protein 8a 3.8169
MFAP5 microfibrillar associated protein 5 3.8169
ADAD2 adenosine deaminase domain containing 2 3.8169
FHL5 four and a half LIM domains 5 3.8169
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 3.8169
CX3CR1 chemokine (C-X3-C motif) receptor 1 3.8169
DRGX dorsal root ganglia homeobox 3.8169
CLEC14A C-type lectin domain family 14, member A 3.8169
NKX2-6 NK2 homeobox 6 3.8169
WDR38 WD repeat domain 38 3.8169
RAB6D RAB6D, member RAS oncogene family 3.8169
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 3.8169
GBP3 guanylate binding protein 3 3.8169
RPL10L ribosomal protein L10-like 3.8169
KRABD1 KRAB domain containing 1 3.8169
CD300LF CD300 molecule-like family member f 3.8169
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 3.8169
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 3.8169
ACOD1 aconitate decarboxylase 1 3.8169
CALHM5 calcium homeostasis modulator family member 5 3.8169
SPMIP1 sperm microtubule inner protein 1 3.8169
PNMA6F PNMA family member 6F 3.8169
PRRT1B proline rich transmembrane protein 1B 3.8169
CIMAP1B ciliary microtubule associated protein 1B 3.8169
LHFPL7 LHFPL tetraspan subfamily member 7 3.8169
CFAP141 cilia and flagella associated protein 141 3.8169
SPATA46 spermatogenesis associated 46 3.8169
CABCOCO1 ciliary associated calcium binding coiled-coil 1 3.8169
MAGIX MAGI family member, X-linked 3.8169
SELL selectin L 3.8169
TPTE transmembrane phosphatase with tensin homology 3.8169
TLR8 toll-like receptor 8 3.8169
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.8169
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 3.8169
OR51B5 olfactory receptor, family 51, subfamily B, member 5 3.8169
GOLGA6L4 golgin A6 family-like 4 3.8169
MAL mal, T-cell differentiation protein 3.8169
ITK IL2-inducible T-cell kinase 3.8169
C1QTNF9 C1q and tumor necrosis factor related protein 9 3.8169
LSP1 lymphocyte-specific protein 1 3.8169
C4ORF50 chromosome 4 open reading frame 50 3.8169
TIMD4 T-cell immunoglobulin and mucin domain containing 4 3.8169
OOSP1 oocyte secreted protein 1, pseudogene 3.8169
PLD4 phospholipase D family, member 4 3.8169
MTMR11 myotubularin related protein 11 3.8169
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.8169
CCR3 chemokine (C-C motif) receptor 3 3.8169
EXOC3L4 exocyst complex component 3-like 4 3.8169
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.8169
TMC8 transmembrane channel-like 8 3.8169
GOLGA8J golgin A8 family, member J 3.8169
GOLGA6A golgin A6 family, member A 3.8169
PRM1 protamine 1 3.8169
CYSLTR1 cysteinyl leukotriene receptor 1 3.8169
CRYBB2 crystallin, beta B2 3.8169
ARR3 arrestin 3, retinal (X-arrestin) 3.8169
KLHL6 kelch-like family member 6 3.8169
EHF ets homologous factor 3.8169
C10ORF120 chromosome 10 open reading frame 120 3.8169
KRT13 keratin 13, type I 3.8169
SMYD1 SET and MYND domain containing 1 3.8169
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.8169
TCF21 transcription factor 21 3.8169
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 3.8169
MAPK11 mitogen-activated protein kinase 11 3.8169
CSF3R colony stimulating factor 3 receptor (granulocyte) 3.8169
PLGLB1 plasminogen-like B1 3.8169
CALHM3 calcium homeostasis modulator 3 3.8169
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 3.8169
LRRN4 leucine rich repeat neuronal 4 3.8169
LAMB4 laminin, beta 4 3.8169
PCDHAC2 protocadherin alpha subfamily C, 2 3.8169
TSPAN19 tetraspanin 19 3.8169
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 3.8169
CTSW cathepsin W 3.8169
SYNGR4 synaptogyrin 4 3.8169
PDCD1LG2 programmed cell death 1 ligand 2 3.8169
PTHLH parathyroid hormone-like hormone 3.8169
ITGA10 integrin, alpha 10 3.8169
IGF2 insulin-like growth factor 2 3.8169
THBD thrombomodulin 3.8169
VWA7 von Willebrand factor A domain containing 7 3.8169
IFITM5 interferon induced transmembrane protein 5 3.8169
CGB1 chorionic gonadotropin, beta polypeptide 1 3.8169
RANBP3L RAN binding protein 3-like 3.8169
FADS6 fatty acid desaturase 6 3.8169
TGM5 transglutaminase 5 3.8169
CCDC87 coiled-coil domain containing 87 3.8169
APOL3 apolipoprotein L, 3 3.8169
FGF6 fibroblast growth factor 6 3.8169
PTCRA pre T-cell antigen receptor alpha 3.8169
PANO1 proapoptotic nucleolar protein 1 3.8169
CLEC2B C-type lectin domain family 2, member B 3.8169
ANGPTL5 angiopoietin-like 5 3.8169
ANXA8 annexin A8 3.8169
CCDC89 coiled-coil domain containing 89 3.8169
MRGPRX3 MAS-related GPR, member X3 3.8169
MT1M metallothionein 1M 3.8169
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 3.8169
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.8169
FGF17 fibroblast growth factor 17 3.8169
TMEM52B transmembrane protein 52B 3.8169
UBASH3A ubiquitin associated and SH3 domain containing A 3.8169
MMP1 matrix metallopeptidase 1 3.8169
GPX2 glutathione peroxidase 2 3.44017
RTN4RL2 reticulon 4 receptor-like 2 3.41682
CCDC9 coiled-coil domain containing 9 3.39702
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 3.32154
DCLK1 doublecortin-like kinase 1 2.96023
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.95026
ANKRD44 ankyrin repeat domain 44 2.8819
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 2.82252
DEFB131B defensin beta 131B 2.80026
OLFM3 olfactomedin 3 2.79436
DDB1 damage-specific DNA binding protein 1, 127kDa 2.78715
KRT10 keratin 10, type I 2.75784
ATP5MF ATP synthase membrane subunit f 2.69338
BRICD5 BRICHOS domain containing 5 2.60716
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.60716
VCX variable charge, X-linked 2.60716
HIKESHI heat shock protein nuclear import factor hikeshi 2.58729
REEP5 receptor accessory protein 5 2.52032
DTX2 deltex 2, E3 ubiquitin ligase 2.51279
EBAG9 estrogen receptor binding site associated, antigen, 9 2.50648
ANKRD55 ankyrin repeat domain 55 2.4887
ZNF71 zinc finger protein 71 2.45903
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 2.44256
ACY1 aminoacylase 1 2.42691
ZBTB5 zinc finger and BTB domain containing 5 2.38381
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 2.38195
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.38195
LIN28A lin-28 homolog A (C. elegans) 2.37049
C6ORF118 chromosome 6 open reading frame 118 2.33633
CTSV cathepsin V 2.31593
IGIP IgA-inducing protein 2.2964
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 2.29318
MCTP1 multiple C2 domains, transmembrane 1 2.29318
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 2.29318
C1QBP complement component 1, q subcomponent binding protein 2.29283
CSNK1D casein kinase 1, delta 2.28891
TMPRSS6 transmembrane protease, serine 6 2.28062
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.28062
NID1 nidogen 1 2.2787
CASS4 Cas scaffolding protein family member 4 2.27253
ACTN4 actinin, alpha 4 2.26086
RPS15A ribosomal protein S15a 2.24795
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 2.24561
FBXO27 F-box protein 27 2.23794
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 2.23502
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.19705
DEFB134 defensin, beta 134 2.19705
RCC2 regulator of chromosome condensation 2 2.18437
FAM9B family with sequence similarity 9, member B 2.17293
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 2.16014
COPS2 COP9 signalosome subunit 2 2.15611
DDTL D-dopachrome tautomerase-like 2.15318
MED27 mediator complex subunit 27 2.12575
ABHD13 abhydrolase domain containing 13 2.12323
BCDIN3D BCDIN3 domain containing 2.0964
CRYBG2 crystallin beta-gamma domain containing 2 2.09151
RFXANK regulatory factor X-associated ankyrin-containing protein 2.07435
CRNKL1 crooked neck pre-mRNA splicing factor 1 2.06707
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.06422
CRYAB crystallin, alpha B 2.05481
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 2.05075
BRD2 bromodomain containing 2 2.04657
STARD7 StAR-related lipid transfer (START) domain containing 7 2.04225
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2.04157
LOC124902694 uncharacterized LOC124902694 2.02972
STX4 syntaxin 4 2.02919
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 2.0014
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.0014
BOD1 biorientation of chromosomes in cell division 1 2.0014

decreased expression

Symbol Name Standardized Value
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -3.8759
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -3.8759
ZNF492 zinc finger protein 492 -3.8759
ACP7 acid phosphatase 7, tartrate resistant (putative) -3.8759
NOTO notochord homeobox -3.8759
CD160 CD160 molecule -3.8759
NPR2 natriuretic peptide receptor 2 -3.8759
EMCN endomucin -3.8169
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) -3.8169
ICAM5 intercellular adhesion molecule 5, telencephalin -3.8169
CXCL14 chemokine (C-X-C motif) ligand 14 -3.8169
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -3.8169
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -3.8169
OR2B6 olfactory receptor, family 2, subfamily B, member 6 -3.8169
MMP28 matrix metallopeptidase 28 -3.8169
NALCN sodium leak channel, non selective -3.8169
EIF2D eukaryotic translation initiation factor 2D -3.8169
NDRG1 N-myc downstream regulated 1 -3.8169
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -3.8169
PDZD9 PDZ domain containing 9 -3.8169
PLIN4 perilipin 4 -3.8169
PLA2G4E phospholipase A2, group IVE -3.8169
ADGRG7 adhesion G protein-coupled receptor G7 -3.8169
PCDHGB4 protocadherin gamma subfamily B, 4 -3.8169
TNNI1 troponin I type 1 (skeletal, slow) -3.8169
ZFP92 ZFP92 zinc finger protein -3.8169
TERB1 telomere repeat binding bouquet formation protein 1 -3.8169
CALR3 calreticulin 3 -3.8169
SMIM38 small integral membrane protein 38 -3.8169
LY6G6D lymphocyte antigen 6 complex, locus G6D -3.8169
ABLIM3 actin binding LIM protein family, member 3 -3.8169
CPNE8-AS1 CPNE8 antisense RNA 1 -3.8169
EFCAB9 EF-hand calcium binding domain 9 -3.8169
SEZ6L seizure related 6 homolog (mouse)-like -3.8169
CFAP100 cilia and flagella associated protein 100 -3.8169
ARFIP1 ADP-ribosylation factor interacting protein 1 -3.30388
DESI1 desumoylating isopeptidase 1 -3.22065
VGF VGF nerve growth factor inducible -3.16249
TPM1 tropomyosin 1 (alpha) -3.08898
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -3.08277
TCF24 transcription factor 24 -3.01423
PCDHB14 protocadherin beta 14 -3.01412
PDCL2 phosducin-like 2 -3.01412
CD164L2 CD164 sialomucin-like 2 -2.99844
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 -2.99341
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -2.99341
LURAP1L leucine rich adaptor protein 1-like -2.99341
PRRT1 proline-rich transmembrane protein 1 -2.99341
MTMR9 myotubularin related protein 9 -2.8819
ZSCAN22 zinc finger and SCAN domain containing 22 -2.88181
MYO7A myosin VIIA -2.88181
SP140 SP140 nuclear body protein -2.88181
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -2.80963
RTKN rhotekin -2.79715
TMEM63B transmembrane protein 63B -2.69338
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 -2.6475
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 -2.64591
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -2.61192
HMOX1 heme oxygenase 1 -2.54987
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.53562
LYG2 lysozyme G-like 2 -2.53562
APH1B APH1B gamma secretase subunit -2.51101
RBBP5 retinoblastoma binding protein 5 -2.49157
MORN1 MORN repeat containing 1 -2.47027
CEP104 centrosomal protein 104kDa -2.46381
ZNF395 zinc finger protein 395 -2.42691
SRRT serrate, RNA effector molecule -2.42691
ANKRD36B ankyrin repeat domain 36B -2.38449
ELF4 E74-like factor 4 (ets domain transcription factor) -2.38449
SLC16A6 solute carrier family 16, member 6 -2.38449
CYB561 cytochrome b561 -2.38222
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -2.37642
MTX3 metaxin 3 -2.34367
ADISSP adipose secreted signaling protein -2.33765
PCGF3 polycomb group ring finger 3 -2.29447
CFAP144 cilia and flagella associated protein 144 -2.26858
SNAP91 synaptosomal-associated protein, 91kDa -2.26858
PDE7B phosphodiesterase 7B -2.26858
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -2.26858
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -2.26282
TMEM209 transmembrane protein 209 -2.26086
HMX2 H6 family homeobox 2 -2.26086
SYTL3 synaptotagmin-like 3 -2.26086
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.24561
EMP3 epithelial membrane protein 3 -2.21301
PGS1 phosphatidylglycerophosphate synthase 1 -2.18437
SELENOI selenoprotein I -2.17733
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.17525
SFXN4 sideroflexin 4 -2.17293
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.13501
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -2.11866
GOPC golgi-associated PDZ and coiled-coil motif containing -2.07435
IER3 immediate early response 3 -2.07353
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 -2.05769
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -2.05596
BICC1 BicC family RNA binding protein 1 -2.05481
RFC3 replication factor C (activator 1) 3, 38kDa -2.05075
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -2.04577
MEST mesoderm specific transcript -2.03938
ZMYM6 zinc finger, MYM-type 6 -2.03921
CKB creatine kinase, brain -2.03266
SNX5 sorting nexin 5 -2.03266
MAPKAP1 mitogen-activated protein kinase associated protein 1 -2.0014
FOXM1 forkhead box M1 -2.0014