TEC Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description tec protein tyrosine kinase|The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7006)
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100 substrates of the kinase TEC from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 99.94
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 99.89
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 99.83
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 99.82
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 99.8
UBE2E2 ubiquitin-conjugating enzyme E2E 2 99.74
UBE2E3 ubiquitin-conjugating enzyme E2E 3 99.74
UBE2E1 ubiquitin-conjugating enzyme E2E 1 99.74
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 99.69
FHIT fragile histidine triad 99.63
TCHP trichoplein, keratin filament binding 99.61
PCYOX1 prenylcysteine oxidase 1 99.58
LOC102725035 leukocyte immunoglobulin-like receptor subfamily B member 3 99.54
CNOT9 CCR4-NOT transcription complex subunit 9 99.47
CD300LB CD300 molecule-like family member b 99.45
PTPRB protein tyrosine phosphatase, receptor type, B 99.43
SMC4 structural maintenance of chromosomes 4 99.41
CKAP4 cytoskeleton-associated protein 4 99.36
ZCCHC3 zinc finger, CCHC domain containing 3 99.34
RFTN1 raftlin, lipid raft linker 1 99.26
SCAF8 SR-related CTD-associated factor 8 99.19
RGS10 regulator of G-protein signaling 10 99.17
SPATA5L1 spermatogenesis associated 5-like 1 99.12
CHD2 chromodomain helicase DNA binding protein 2 99.02
FBXO9 F-box protein 9 99.01
RPS10 ribosomal protein S10 98.99
RPS10-NUDT3 RPS10-NUDT3 readthrough 98.99
DPH6 diphthamine biosynthesis 6 98.93
SIPA1L1 signal-induced proliferation-associated 1 like 1 98.88
EXPH5 exophilin 5 98.86
ELP3 elongator acetyltransferase complex subunit 3 98.83
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 98.77
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 98.75
PTPRH protein tyrosine phosphatase, receptor type, H 98.69
KAT2B K(lysine) acetyltransferase 2B 98.67
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 98.64
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 98.56
UBA7 ubiquitin-like modifier activating enzyme 7 98.55
RABGAP1L RAB GTPase activating protein 1-like 98.53
FCMR Fc fragment of IgM receptor 98.45
BCAS2 breast carcinoma amplified sequence 2 98.43
CEP89 centrosomal protein 89kDa 98.34
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 98.32
LY6G6F lymphocyte antigen 6 complex, locus G6F 98.31
SMG8 SMG8 nonsense mediated mRNA decay factor 98.25
KAT2A K(lysine) acetyltransferase 2A 98.21
PSME3IP1 proteasome activator subunit 3 interacting protein 1 98.18
AP1AR adaptor-related protein complex 1 associated regulatory protein 98.16
DOK3 docking protein 3 98.07
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 98.05
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 97.86
NFYA nuclear transcription factor Y, alpha 97.83
FKBP6 FK506 binding protein 6, 36kDa 97.77
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 97.75
PLCL2 phospholipase C-like 2 97.74
RRM1 ribonucleotide reductase M1 97.7
RPL10A ribosomal protein L10a 97.68
ZNF169 zinc finger protein 169 97.57
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 97.4
KLC3 kinesin light chain 3 97.35
TGFB1I1 transforming growth factor beta 1 induced transcript 1 97.33
CD244 CD244 molecule, natural killer cell receptor 2B4 97.32
SVBP small vasohibin binding protein 97.31
GEMIN8 gem (nuclear organelle) associated protein 8 97.29
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 97.27
KMT5A lysine methyltransferase 5A 97.22
SH3GLB2 SH3-domain GRB2-like endophilin B2 97.2
N4BP2 NEDD4 binding protein 2 97.15
CHERP calcium homeostasis endoplasmic reticulum protein 97.09
TRIM25 tripartite motif containing 25 97.07
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 97.04
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 97.04
MTOR mechanistic target of rapamycin (serine/threonine kinase) 97.0
RPS29 ribosomal protein S29 96.96
TEX2 testis expressed 2 96.94
STARD13 StAR-related lipid transfer (START) domain containing 13 96.87
MCRIP1 MAPK regulated corepressor interacting protein 1 96.72
MX2 MX dynamin-like GTPase 2 96.7
RASGRP4 RAS guanyl releasing protein 4 96.7
ACOX1 acyl-CoA oxidase 1, palmitoyl 96.67
RPS16 ribosomal protein S16 96.65
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 96.63
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 96.59
GMPPA GDP-mannose pyrophosphorylase A 96.58
CZIB CXXC motif containing zinc binding protein 96.54
RGS14 regulator of G-protein signaling 14 96.52
RBM25 RNA binding motif protein 25 96.48
MPZL1 myelin protein zero-like 1 96.39
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 96.35
PBX2 pre-B-cell leukemia homeobox 2 96.32
RPL36AL ribosomal protein L36a-like 96.23
STING1 stimulator of interferon response cGAMP interactor 1 96.13
UMPS uridine monophosphate synthetase 96.1
EGR1 early growth response 1 96.0
FHOD1 formin homology 2 domain containing 1 95.91
SRCIN1 SRC kinase signaling inhibitor 1 95.875
MEMO1 mediator of cell motility 1 95.84
LY9 lymphocyte antigen 9 95.83
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 95.82
FCRL6 Fc receptor-like 6 95.75