TEC Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description tec protein tyrosine kinase|The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7006)
External Link https://ncbi.nlm.nih.gov/gene/7006
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Genes

500 genes differentially expressed following the TEC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TCTA T-cell leukemia translocation altered 0.0115952
CANT1 calcium activated nucleotidase 1 0.0108603
SEPP1 selenoprotein P, plasma, 1 0.0107042
MFAP5 microfibrillar associated protein 5 0.0105251
PCNA proliferating cell nuclear antigen 0.00983546
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.009365
RNPS1 RNA binding protein S1, serine-rich domain 0.00917831
TSPAN13 tetraspanin 13 0.00916207
CXCL14 chemokine (C-X-C motif) ligand 14 0.00826397
DCK deoxycytidine kinase 0.0082504
GPNMB glycoprotein (transmembrane) nmb 0.00824572
TM4SF1 transmembrane 4 L six family member 1 0.00797033
PCCB propionyl CoA carboxylase, beta polypeptide 0.00795639
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00795026
FABP4 fatty acid binding protein 4, adipocyte 0.00782546
CPB1 carboxypeptidase B1 (tissue) 0.00781972
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00781253
MT1E metallothionein 1E 0.00775036
HIST1H2BK histone cluster 1, H2bk 0.0075898
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0075047
CD320 CD320 molecule 0.00746753
FGF13 fibroblast growth factor 13 0.00740322
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.0073586
THBS2 thrombospondin 2 0.00733651
CD99 CD99 molecule 0.00721987
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.00718858
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00715887
SRPX sushi-repeat containing protein, X-linked 0.00712864
ANKRD10 ankyrin repeat domain 10 0.0071271
SPRR1B small proline-rich protein 1B 0.0071195
TMX4 thioredoxin-related transmembrane protein 4 0.00705107
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00704155
TIMP3 TIMP metallopeptidase inhibitor 3 0.00701546
CAVIN3 caveolae associated protein 3 0.00699566
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00698088
REXO2 RNA exonuclease 2 0.0069472
ANPEP alanyl (membrane) aminopeptidase 0.00694092
HOXB7 homeobox B7 0.00687882
EMP1 epithelial membrane protein 1 0.00685175
COMT catechol-O-methyltransferase 0.00681676
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00669601
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00669286
S100A10 S100 calcium binding protein A10 0.006683
TAGLN transgelin 0.00664333
FXYD3 FXYD domain containing ion transport regulator 3 0.00664032
TSPAN1 tetraspanin 1 0.0066284
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00658388
S100A4 S100 calcium binding protein A4 0.00657008
SCAND1 SCAN domain containing 1 0.0065516
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00655146
TCF4 transcription factor 4 0.00650578
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00648808
SNAP23 synaptosomal-associated protein, 23kDa 0.00647498
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.00647434
ARG2 arginase 2 0.0064483
CLINT1 clathrin interactor 1 0.00643402
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00637203
STK10 serine/threonine kinase 10 0.00636925
IGFBP6 insulin-like growth factor binding protein 6 0.00636878
STK17A serine/threonine kinase 17a 0.00634218
RABAC1 Rab acceptor 1 (prenylated) 0.00628622
JAG1 jagged 1 0.00628467
HOXB2 homeobox B2 0.0062451
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00622519
CCL19 chemokine (C-C motif) ligand 19 0.00622154
OSBPL10 oxysterol binding protein-like 10 0.0062182
KRT14 keratin 14, type I 0.00621441
CSRP1 cysteine and glycine-rich protein 1 0.00617535
CLTB clathrin, light chain B 0.00616932
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.00616046
LYPD1 LY6/PLAUR domain containing 1 0.00615163
SHROOM2 shroom family member 2 0.00613429
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00610416
PLS3 plastin 3 0.00609688
COX17 COX17 cytochrome c oxidase copper chaperone 0.00609612
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.00603277
MRPS30 mitochondrial ribosomal protein S30 0.00603172
LAMA3 laminin, alpha 3 0.00602354
CSTA cystatin A (stefin A) 0.00600632
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00597148
DERA deoxyribose-phosphate aldolase (putative) 0.00596479
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00588362
CERS2 ceramide synthase 2 0.00585641
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00581827
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00581661
MYL12B myosin, light chain 12B, regulatory 0.00581054
PTPRK protein tyrosine phosphatase, receptor type, K 0.00580363
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00577728
FOXO1 forkhead box O1 0.00577703
GRWD1 glutamate-rich WD repeat containing 1 0.00575463
IL1RAP interleukin 1 receptor accessory protein 0.00569958
TMEM230 transmembrane protein 230 0.00568623
CPNE1 copine I 0.00568534
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 0.00567067
IL1A interleukin 1, alpha 0.00565955
TENT5A terminal nucleotidyltransferase 5A 0.00565541
PDLIM2 PDZ and LIM domain 2 (mystique) 0.00565028
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00563986
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00561004
CCL21 chemokine (C-C motif) ligand 21 0.00560793
PTK2 protein tyrosine kinase 2 0.00558336
WT1 Wilms tumor 1 0.00554499
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.00553217
DAAM1 dishevelled associated activator of morphogenesis 1 0.00553039
C5ORF28 chromosome 5 open reading frame 28 0.00550646
SF3B5 splicing factor 3b, subunit 5, 10kDa 0.00550189
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00549602
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00548964
MGST2 microsomal glutathione S-transferase 2 0.00544148
ANXA4 annexin A4 0.00543847
FN1 fibronectin 1 0.00543672
RCAN1 regulator of calcineurin 1 0.00542257
CAB39 calcium binding protein 39 0.00540303
PDGFC platelet derived growth factor C 0.00538245
NEK7 NIMA-related kinase 7 0.00535201
SCRG1 stimulator of chondrogenesis 1 0.00534861
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 0.00533089
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00532288
ATOX1 antioxidant 1 copper chaperone 0.00529765
TRIM22 tripartite motif containing 22 0.00529509
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0052948
VAMP5 vesicle-associated membrane protein 5 0.00529387
HOPX HOP homeobox 0.00528492
PDHX pyruvate dehydrogenase complex, component X 0.00523318
KANK1 KN motif and ankyrin repeat domains 1 0.00521876
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00521048
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00520041
MZT2A mitotic spindle organizing protein 2A 0.00519917
LIF leukemia inhibitory factor 0.00518884
ACAT1 acetyl-CoA acetyltransferase 1 0.00518455
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0051841
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00511666
PRSS8 protease, serine, 8 0.00510605
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00510173
TRIB3 tribbles pseudokinase 3 0.00509957
ADIPOR2 adiponectin receptor 2 0.00508503
SH3BP4 SH3-domain binding protein 4 0.005083
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.00507785
XYLT1 xylosyltransferase I 0.00506791
NUPR1 nuclear protein, transcriptional regulator, 1 0.00506368
RPS27L ribosomal protein S27-like 0.00505685
HSPB1 heat shock 27kDa protein 1 0.0050405
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00503964
CLEC2B C-type lectin domain family 2, member B 0.00502813
NT5E 5'-nucleotidase, ecto (CD73) 0.00502567
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.00501202
MRPL22 mitochondrial ribosomal protein L22 0.00495705
TLN1 talin 1 0.00494947
SMAGP small cell adhesion glycoprotein 0.00494365
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00492934
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 0.00492444
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00492421
PLAT plasminogen activator, tissue 0.00491836
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00491612
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.00488996
ABHD3 abhydrolase domain containing 3 0.00488219
PRNP prion protein 0.0048779
AMACR alpha-methylacyl-CoA racemase 0.00485737
DYNLT3 dynein, light chain, Tctex-type 3 0.00485389
BMP2 bone morphogenetic protein 2 0.00485045
SCEL sciellin 0.00484597
HMOX2 heme oxygenase 2 0.00484496
CCND2 cyclin D2 0.00484394
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0048129
GRB7 growth factor receptor-bound protein 7 0.00480669
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00480027
FLNB filamin B, beta 0.00479595
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00478719
SNX10 sorting nexin 10 0.00475868
GATA6 GATA binding protein 6 0.00475815
AKAP12 A kinase (PRKA) anchor protein 12 0.00475801
FRMD4B FERM domain containing 4B 0.00475314
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00474447
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.00474427
SERTAD2 SERTA domain containing 2 0.0047428
PDLIM4 PDZ and LIM domain 4 0.00474218
CD58 CD58 molecule 0.00471571
APRT adenine phosphoribosyltransferase 0.00470015
C12ORF29 chromosome 12 open reading frame 29 0.00468904
SLBP stem-loop binding protein 0.00468392
SRCAP Snf2-related CREBBP activator protein 0.00467917
NOTCH2 notch 2 0.00467675
MALL mal, T-cell differentiation protein-like 0.00466902
EFNA1 ephrin-A1 0.00466147
TGIF1 TGFB-induced factor homeobox 1 0.00465892
DAP death-associated protein 0.00465055
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00461966
SMTN smoothelin 0.00461761
POF1B premature ovarian failure, 1B 0.00461132
KLHL9 kelch-like family member 9 0.00457863
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00457517
NOP10 NOP10 ribonucleoprotein 0.00457231
FAR2 fatty acyl CoA reductase 2 0.00456735
MTUS1 microtubule associated tumor suppressor 1 0.00455457
LAMA4 laminin, alpha 4 0.00453152
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.00451862
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.00451706
KLF5 Kruppel-like factor 5 (intestinal) 0.00451699
CDC20 cell division cycle 20 0.00450609
FASTKD5 FAST kinase domains 5 0.00450087
SNRK SNF related kinase 0.00450025
TXNDC9 thioredoxin domain containing 9 0.00449997
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00449822
PPAP2A phosphatidic acid phosphatase type 2A 0.00449298
MED21 mediator complex subunit 21 0.00448637
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00448414
APLP2 amyloid beta (A4) precursor-like protein 2 0.00447879
CALR calreticulin 0.00447492
ELOB elongin B 0.00447051
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00446813
SNRPB2 small nuclear ribonucleoprotein polypeptide B 0.0044667
ANXA9 annexin A9 0.00443506
RPL36 ribosomal protein L36 0.00443258
AMD1 adenosylmethionine decarboxylase 1 0.00443249
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.00443187
OCRL oculocerebrorenal syndrome of Lowe 0.00443057
TWSG1 twisted gastrulation BMP signaling modulator 1 0.00442735
TGFBI transforming growth factor, beta-induced, 68kDa 0.00441986
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0044189
TJP2 tight junction protein 2 0.00441543
DYNLRB1 dynein, light chain, roadblock-type 1 0.0044134
TPST1 tyrosylprotein sulfotransferase 1 0.00440433
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.00439669
SAR1B secretion associated, Ras related GTPase 1B 0.00438688
AHNAK2 AHNAK nucleoprotein 2 0.00438648
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00437992
PHB prohibitin 0.00437565
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00436818
BOLA1 bolA family member 1 0.00435617
MPG N-methylpurine-DNA glycosylase 0.00435192
NDRG1 N-myc downstream regulated 1 0.00435057
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00434771
STK32B serine/threonine kinase 32B 0.00434529
SMS spermine synthase 0.0043422
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00433648
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00431618
ATP10D ATPase, class V, type 10D 0.00430972
MEOX2 mesenchyme homeobox 2 0.00429629
PROCR protein C receptor, endothelial 0.00429579
FKBP11 FK506 binding protein 11, 19 kDa 0.00429536
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0042884
CXCL6 chemokine (C-X-C motif) ligand 6 0.0042845
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.004284
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.00427917
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.0042774
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00425327
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.00425295
UBE2S ubiquitin-conjugating enzyme E2S 0.00424809
ECM1 extracellular matrix protein 1 0.00424495
PXDC1 PX domain containing 1 0.00424392

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -0.0132357
G0S2 G0/G1 switch 2 -0.0115585
OLFM4 olfactomedin 4 -0.0110951
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0105174
WFDC1 WAP four-disulfide core domain 1 -0.0101095
MMP12 matrix metallopeptidase 12 -0.00993833
EIF5A eukaryotic translation initiation factor 5A -0.00954267
ZBTB18 zinc finger and BTB domain containing 18 -0.00937876
GREB1 growth regulation by estrogen in breast cancer 1 -0.00926769
CYBB cytochrome b-245, beta polypeptide -0.00906971
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00882571
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00875295
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00871036
MYBPC1 myosin binding protein C, slow type -0.00851912
NAV2 neuron navigator 2 -0.00840612
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00833223
NEBL nebulette -0.00829979
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00818155
FBP1 fructose-1,6-bisphosphatase 1 -0.00815
FTH1 ferritin, heavy polypeptide 1 -0.00806466
ZIC1 Zic family member 1 -0.00783406
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00775038
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0077111
TTN titin -0.00771048
KYNU kynureninase -0.00765579
PSAP prosaposin -0.0074243
RTN2 reticulon 2 -0.00736501
WARS1 tryptophanyl-tRNA synthetase 1 -0.00727241
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00723199
RRAGD Ras-related GTP binding D -0.00721599
MYBPC2 myosin binding protein C, fast type -0.00717836
LDB3 LIM domain binding 3 -0.00708558
NTS neurotensin -0.00706221
CCNB1 cyclin B1 -0.00703993
ACTA1 actin, alpha 1, skeletal muscle -0.00701832
SCRIB scribbled planar cell polarity protein -0.00699948
LY6E lymphocyte antigen 6 complex, locus E -0.00699665
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00699068
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00692441
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00690957
AZIN1 antizyme inhibitor 1 -0.00686433
F3 coagulation factor III (thromboplastin, tissue factor) -0.00685
CD83 CD83 molecule -0.00684765
IL7R interleukin 7 receptor -0.00684416
IDO1 indoleamine 2,3-dioxygenase 1 -0.00681292
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00677619
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00675653
RAP2A RAP2A, member of RAS oncogene family -0.00672249
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.00664732
PRPF4 pre-mRNA processing factor 4 -0.00660587
TUBB2A tubulin, beta 2A class IIa -0.00660194
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00659462
DLK1 delta-like 1 homolog (Drosophila) -0.00658847
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.00654185
ENO3 enolase 3 (beta, muscle) -0.00646563
ASRGL1 asparaginase like 1 -0.00646097
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00643808
EFHD1 EF-hand domain family, member D1 -0.006436
PBX3 pre-B-cell leukemia homeobox 3 -0.00642857
RHOBTB3 Rho-related BTB domain containing 3 -0.00641203
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00634397
COLEC11 collectin sub-family member 11 -0.00633475
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00631156
ZNF423 zinc finger protein 423 -0.00631009
RXYLT1 ribitol xylosyltransferase 1 -0.00629637
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00628578
CRABP1 cellular retinoic acid binding protein 1 -0.00626015
NRIP3 nuclear receptor interacting protein 3 -0.0062545
LIMCH1 LIM and calponin homology domains 1 -0.00623939
ACKR3 atypical chemokine receptor 3 -0.00614203
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00613154
TADA2A transcriptional adaptor 2A -0.00612956
BHLHE41 basic helix-loop-helix family, member e41 -0.00609783
GALC galactosylceramidase -0.00609636
TTC3 tetratricopeptide repeat domain 3 -0.00607526
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 -0.0060677
DEPTOR DEP domain containing MTOR-interacting protein -0.00604786
TUBA1A tubulin, alpha 1a -0.00603457
MNDA myeloid cell nuclear differentiation antigen -0.006022
PGD phosphogluconate dehydrogenase -0.00601909
SH2B2 SH2B adaptor protein 2 -0.00595858
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00592339
PLPP3 phospholipid phosphatase 3 -0.00592037
CCP110 centriolar coiled coil protein 110kDa -0.00591255
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00590494
ADCY1 adenylate cyclase 1 (brain) -0.00587306
FZD1 frizzled class receptor 1 -0.00587228
ARPP21 cAMP-regulated phosphoprotein, 21kDa -0.00587
RGCC regulator of cell cycle -0.00586145
C8ORF33 chromosome 8 open reading frame 33 -0.00583394
PDZRN3 PDZ domain containing ring finger 3 -0.00583254
TNNC2 troponin C type 2 (fast) -0.00577199
PLPP2 phospholipid phosphatase 2 -0.00575818
LY75 lymphocyte antigen 75 -0.00575597
NPTX2 neuronal pentraxin II -0.00575544
CYBA cytochrome b-245, alpha polypeptide -0.00575346
FAM171A1 family with sequence similarity 171, member A1 -0.00574385
GLUL glutamate-ammonia ligase -0.00572547
LCN2 lipocalin 2 -0.0056781
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00566118
FAM189A2 family with sequence similarity 189, member A2 -0.00565677
ANOS1 anosmin 1 -0.00565357
RBM34 RNA binding motif protein 34 -0.00565274
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00563589
COL4A5 collagen, type IV, alpha 5 -0.00562415
ACTC1 actin, alpha, cardiac muscle 1 -0.00561232
TNNC1 troponin C type 1 (slow) -0.00560113
LAPTM4B lysosomal protein transmembrane 4 beta -0.00557605
PROM1 prominin 1 -0.00556225
NXN nucleoredoxin -0.00555838
AK4 adenylate kinase 4 -0.00553744
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.00548403
RGS1 regulator of G-protein signaling 1 -0.00548291
COL5A1 collagen, type V, alpha 1 -0.00547481
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00546538
PDE8B phosphodiesterase 8B -0.00541708
FOXG1 forkhead box G1 -0.00540815
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00540458
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00540274
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00539746
CKM creatine kinase, muscle -0.00539444
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00539421
AUTS2 autism susceptibility candidate 2 -0.00538923
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.00538476
SLN sarcolipin -0.00537255
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.00537209
GPM6A glycoprotein M6A -0.00535427
C6ORF48 chromosome 6 open reading frame 48 -0.00533036
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00532062
PLCB4 phospholipase C, beta 4 -0.00531766
IFI44L interferon-induced protein 44-like -0.0053122
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00530593
IVNS1ABP influenza virus NS1A binding protein -0.0052977
ARMCX3 armadillo repeat containing, X-linked 3 -0.00527045
GPM6B glycoprotein M6B -0.00526987
FCGBP Fc fragment of IgG binding protein -0.00526135
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00525176
CLC Charcot-Leyden crystal galectin -0.00525129
TESC tescalcin -0.00523032
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00522204
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00521655
TNNT1 troponin T type 1 (skeletal, slow) -0.00520075
HMGN5 high mobility group nucleosome binding domain 5 -0.00518689
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.00518214
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00517835
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00517633
ZMYM2 zinc finger, MYM-type 2 -0.00517371
KLHL41 kelch-like family member 41 -0.00516834
MAP1B microtubule-associated protein 1B -0.00516598
DLG5 discs, large homolog 5 (Drosophila) -0.00512198
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00512129
DUOX2 dual oxidase 2 -0.00510397
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00508126
SLC16A6 solute carrier family 16, member 6 -0.0050792
MYL4 myosin, light chain 4, alkali; atrial, embryonic -0.0050781
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00507757
IFI6 interferon, alpha-inducible protein 6 -0.0050755
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00507481
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -0.00507162
HELLS helicase, lymphoid-specific -0.00506348
PRAME preferentially expressed antigen in melanoma -0.00505762
SIRT3 sirtuin 3 -0.00505485
SCGB2A1 secretoglobin, family 2A, member 1 -0.00505324
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00505017
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00504815
UBXN7 UBX domain protein 7 -0.00503069
ITM2A integral membrane protein 2A -0.00502861
FOXF2 forkhead box F2 -0.00502788
CD38 CD38 molecule -0.0050249
PCYOX1 prenylcysteine oxidase 1 -0.00501997
WNT5A wingless-type MMTV integration site family, member 5A -0.0050055
EIF5 eukaryotic translation initiation factor 5 -0.00499896
TRPS1 trichorhinophalangeal syndrome I -0.004986
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0049692
ANXA6 annexin A6 -0.00496825
FZD10 frizzled class receptor 10 -0.00496592
KRT19 keratin 19, type I -0.00495523
ANO1 anoctamin 1, calcium activated chloride channel -0.00495244
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00494945
LMNB1 lamin B1 -0.00494531
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00492846
CHIT1 chitinase 1 (chitotriosidase) -0.00492165
NBPF10 neuroblastoma breakpoint family, member 10 -0.00491731
ZNF106 zinc finger protein 106 -0.00488549
AOC1 amine oxidase, copper containing 1 -0.00488531
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00487666
GSTM3 glutathione S-transferase mu 3 (brain) -0.00486973
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00486476
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00486375
CAPN3 calpain 3, (p94) -0.00485063
LEFTY1 left-right determination factor 1 -0.0048505
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.00484825
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00481168
GRN granulin -0.00480376
KRT13 keratin 13, type I -0.0047768
PBX1 pre-B-cell leukemia homeobox 1 -0.00477632
FGR FGR proto-oncogene, Src family tyrosine kinase -0.00477239
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00476707
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00476369
ENAH enabled homolog (Drosophila) -0.00475902
FOXE1 forkhead box E1 -0.00474961
CTSS cathepsin S -0.00474538
SFTPA2 surfactant protein A2 -0.00474379
TFRC transferrin receptor -0.00473727
FBXO21 F-box protein 21 -0.00473496
COCH cochlin -0.00471247
NFIB nuclear factor I/B -0.00470915
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00469732
LAMP3 lysosomal-associated membrane protein 3 -0.00468621
PALLD palladin, cytoskeletal associated protein -0.0046836
IGFBP5 insulin-like growth factor binding protein 5 -0.00467512
DMBT1 deleted in malignant brain tumors 1 -0.00466002
DLX5 distal-less homeobox 5 -0.00465392
OGFRL1 opioid growth factor receptor-like 1 -0.00464828
TMPRSS4 transmembrane protease, serine 4 -0.00464546
OXA1L oxidase (cytochrome c) assembly 1-like -0.00462366
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00460984
CST1 cystatin SN -0.004595
PCP4 Purkinje cell protein 4 -0.00459089
CES1 carboxylesterase 1 -0.00458944
FADS1 fatty acid desaturase 1 -0.00458432
COL1A2 collagen, type I, alpha 2 -0.00457611
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0045479
KRT23 keratin 23, type I -0.00454154
TAPBP TAP binding protein (tapasin) -0.00453283
SH3BGR SH3 domain binding glutamate-rich protein -0.00453205
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00451953
GMPR guanosine monophosphate reductase -0.00451402
GCLC glutamate-cysteine ligase, catalytic subunit -0.00449876
FOXF1 forkhead box F1 -0.00449865
CHD7 chromodomain helicase DNA binding protein 7 -0.00448763
VNN1 vanin 1 -0.0044851
MTARC1 mitochondrial amidoxime reducing component 1 -0.00448252
FMO3 flavin containing monooxygenase 3 -0.00448169
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00446893
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00446749
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.00446439
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 -0.00446271
PHACTR4 phosphatase and actin regulator 4 -0.00445412
MX1 MX dynamin-like GTPase 1 -0.00445068
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -0.00444974
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.00444959
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00444663
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00444507
ADD3 adducin 3 (gamma) -0.00444238
JCHAIN joining chain of multimeric IgA and IgM -0.00444206
LRP4 low density lipoprotein receptor-related protein 4 -0.0044395
TNNI2 troponin I type 2 (skeletal, fast) -0.00443783
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.00442101
SOBP sine oculis binding protein homolog (Drosophila) -0.00441931