TEC Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description tec protein tyrosine kinase|The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7006)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GCM_TEC
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Genes

32 co-expressed genes for TEC from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
APOC3 apolipoprotein C-III
AVPR1B arginine vasopressin receptor 1B
CCR9 chemokine (C-C motif) receptor 9
CD8B CD8b molecule
CHIC1 cysteine-rich hydrophobic domain 1
CHRM5 cholinergic receptor, muscarinic 5
DGCR6 DiGeorge syndrome critical region gene 6
FANCC Fanconi anemia, complementation group C
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FEV FEV (ETS oncogene family)
GRM4 glutamate receptor, metabotropic 4
HMGA2 high mobility group AT-hook 2
IFNA21 interferon, alpha 21
KRT83 keratin 83, type II
MADD MAP-kinase activating death domain
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MVK mevalonate kinase
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRF1 nuclear respiratory factor 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PTPRU protein tyrosine phosphatase, receptor type, U
RING1 ring finger protein 1
SLC17A2 solute carrier family 17, member 2
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
TMEM106A transmembrane protein 106A
VAV1 vav 1 guanine nucleotide exchange factor
ZNF8 zinc finger protein 8