TEC Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description tec protein tyrosine kinase|The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7006)
External Link http://www.ncbi.nlm.nih.gov/gene/7006
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Genes

6 substrates of the kinase TEC from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
BMX BMX non-receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
FGF2 fibroblast growth factor 2 (basic)
ITK IL2-inducible T-cell kinase
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
TEC tec protein tyrosine kinase