| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | thyrotrophic embryonic factor|This gene encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 7008) |
| External Link | https://ncbi.nlm.nih.gov/gene/7008 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the TEF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0225816 |
| MAP7 | microtubule-associated protein 7 | 0.0194544 |
| CHKB | choline kinase beta | 0.0183204 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.017941 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0174535 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0153421 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0143326 |
| NVL | nuclear VCP-like | 0.0141172 |
| THY1 | Thy-1 cell surface antigen | 0.0139425 |
| COMP | cartilage oligomeric matrix protein | 0.0137418 |
| SIRT3 | sirtuin 3 | 0.0134365 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0134105 |
| MMP12 | matrix metallopeptidase 12 | 0.0130696 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0126347 |
| REG1A | regenerating islet-derived 1 alpha | 0.0121487 |
| ANXA4 | annexin A4 | 0.0120954 |
| PRSS3 | protease, serine, 3 | 0.0120824 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0120779 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0120344 |
| EZR | ezrin | 0.0117922 |
| NDRG1 | N-myc downstream regulated 1 | 0.0116706 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.0116417 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0115243 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.0111535 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0111164 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.0111129 |
| DCK | deoxycytidine kinase | 0.0110026 |
| EPHB2 | EPH receptor B2 | 0.0109855 |
| TMEM106C | transmembrane protein 106C | 0.0108521 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0107314 |
| CLCA1 | chloride channel accessory 1 | 0.0106344 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0106318 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0105807 |
| ADIRF | adipogenesis regulatory factor | 0.0105232 |
| HEPH | hephaestin | 0.0105039 |
| ARSL | arylsulfatase L | 0.010489 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.010456 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.0104449 |
| COL5A1 | collagen, type V, alpha 1 | 0.0104356 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.0103444 |
| FZD5 | frizzled class receptor 5 | 0.0102612 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0102311 |
| RANBP1 | RAN binding protein 1 | 0.0102042 |
| TOX3 | TOX high mobility group box family member 3 | 0.0101638 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0101274 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0100411 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0100351 |
| IPO13 | importin 13 | 0.00987764 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00987584 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00980647 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00974555 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00969266 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00966819 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00964916 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00963128 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00957569 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00957275 |
| HMGB3 | high mobility group box 3 | 0.00954205 |
| PKP2 | plakophilin 2 | 0.00951809 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00949853 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00943801 |
| PLS3 | plastin 3 | 0.00940152 |
| ZG16 | zymogen granule protein 16 | 0.00932529 |
| CCNG2 | cyclin G2 | 0.00928579 |
| GPX2 | glutathione peroxidase 2 | 0.00921268 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00919581 |
| LRRC15 | leucine rich repeat containing 15 | 0.00919231 |
| CST6 | cystatin E/M | 0.00914627 |
| REG1B | regenerating islet-derived 1 beta | 0.00913284 |
| TYMS | thymidylate synthetase | 0.00910134 |
| KRT20 | keratin 20, type I | 0.00905392 |
| CNN3 | calponin 3, acidic | 0.00903372 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.0090009 |
| SNX7 | sorting nexin 7 | 0.00899196 |
| NOX1 | NADPH oxidase 1 | 0.0089575 |
| ELN | elastin | 0.00891373 |
| CALD1 | caldesmon 1 | 0.00888429 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00887506 |
| MALL | mal, T-cell differentiation protein-like | 0.00883718 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00881854 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00877303 |
| MARCKSL1 | MARCKS-like 1 | 0.0087527 |
| AEBP1 | AE binding protein 1 | 0.00870617 |
| ENO1 | enolase 1, (alpha) | 0.00867988 |
| GLO1 | glyoxalase I | 0.00864881 |
| PLS1 | plastin 1 | 0.00859177 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00858397 |
| GAL | galanin/GMAP prepropeptide | 0.00854635 |
| TPD52 | tumor protein D52 | 0.00854167 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00853423 |
| FABP1 | fatty acid binding protein 1, liver | 0.00852669 |
| LEFTY1 | left-right determination factor 1 | 0.00850828 |
| TMEM14A | transmembrane protein 14A | 0.0084956 |
| PERP | PERP, TP53 apoptosis effector | 0.00843442 |
| PKM | pyruvate kinase, muscle | 0.00838212 |
| CA2 | carbonic anhydrase II | 0.00834303 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00833782 |
| HOPX | HOP homeobox | 0.00833471 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00830248 |
| COL5A2 | collagen, type V, alpha 2 | 0.00830197 |
| PRDX4 | peroxiredoxin 4 | 0.00823733 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00822111 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00818474 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00817297 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00816715 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00816647 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00815207 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00813868 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.0081183 |
| FRZB | frizzled-related protein | 0.00810648 |
| RPA3 | replication protein A3, 14kDa | 0.0081051 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00810109 |
| CENPX | centromere protein X | 0.00805999 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | 0.0080499 |
| S100A9 | S100 calcium binding protein A9 | 0.00801065 |
| GSE1 | Gse1 coiled-coil protein | 0.00799481 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00798782 |
| CBX1 | chromobox homolog 1 | 0.00795628 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00795236 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00795068 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00794843 |
| TMPO | thymopoietin | 0.00790894 |
| GLS | glutaminase | 0.00790501 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.0078886 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 0.00787257 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.00787069 |
| GLOD4 | glyoxalase domain containing 4 | 0.00786125 |
| SMYD3 | SET and MYND domain containing 3 | 0.00785173 |
| MXRA8 | matrix-remodelling associated 8 | 0.00784417 |
| PGK1 | phosphoglycerate kinase 1 | 0.00778536 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00774235 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00771911 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00770516 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.0076899 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00767908 |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.00767699 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.00766846 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00763972 |
| ZNF395 | zinc finger protein 395 | 0.00763437 |
| SLBP | stem-loop binding protein | 0.00762711 |
| RAB20 | RAB20, member RAS oncogene family | 0.0076227 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.00762108 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0076169 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00756644 |
| CDK1 | cyclin-dependent kinase 1 | 0.0075319 |
| IL7 | interleukin 7 | 0.00752551 |
| RXRA | retinoid X receptor, alpha | 0.0075198 |
| IL18 | interleukin 18 | 0.00750957 |
| RHOB | ras homolog family member B | 0.00750657 |
| SATB2 | SATB homeobox 2 | 0.00748273 |
| CA12 | carbonic anhydrase XII | 0.0074726 |
| CCNB1 | cyclin B1 | 0.00745203 |
| FBLN1 | fibulin 1 | 0.00745059 |
| CLCA4 | chloride channel accessory 4 | 0.00744497 |
| RNF19B | ring finger protein 19B | 0.00743733 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00742161 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00741323 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00741072 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00739513 |
| ITM2C | integral membrane protein 2C | 0.00738693 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00738592 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00737922 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.00736226 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00734966 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00734457 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00733892 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00729836 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00728661 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00728084 |
| FAM162A | family with sequence similarity 162, member A | 0.00724648 |
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.0072375 |
| TMEM106B | transmembrane protein 106B | 0.00723634 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00723594 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00720726 |
| DSP | desmoplakin | 0.00720706 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00720224 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00719007 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00718167 |
| SEPTIN11 | septin 11 | 0.00715228 |
| PDE9A | phosphodiesterase 9A | 0.00713752 |
| H1-2 | H1.2 linker histone, cluster member | 0.00713545 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00713448 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 | 0.00713023 |
| TMEM176B | transmembrane protein 176B | 0.00712961 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00711027 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00711015 |
| EPHB6 | EPH receptor B6 | 0.00709917 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00709512 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00709392 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00708995 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00705908 |
| SYNGR3 | synaptogyrin 3 | 0.00705316 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00704723 |
| PANK3 | pantothenate kinase 3 | 0.00703337 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.00702183 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.00700784 |
| COMMD8 | COMM domain containing 8 | 0.00700424 |
| PFKL | phosphofructokinase, liver | 0.00697233 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00695214 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.0069438 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.0069358 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00692814 |
| MEST | mesoderm specific transcript | 0.00687899 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00686751 |
| PDCD10 | programmed cell death 10 | 0.0068597 |
| CD177 | CD177 molecule | 0.00685837 |
| HMGB1 | high mobility group box 1 | 0.00685493 |
| SDC1 | syndecan 1 | 0.00684664 |
| STK39 | serine threonine kinase 39 | 0.0068392 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0068272 |
| ATXN10 | ataxin 10 | 0.00681928 |
| RBM47 | RNA binding motif protein 47 | 0.00674005 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00673557 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.0067329 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00671851 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00668312 |
| FASN | fatty acid synthase | 0.00663665 |
| CNTNAP2 | contactin associated protein-like 2 | 0.0066346 |
| PLAU | plasminogen activator, urokinase | 0.00662544 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00662361 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00661795 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.0066045 |
| LOR | loricrin | 0.00660448 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.00659936 |
| REG3A | regenerating islet-derived 3 alpha | 0.00658362 |
| MYCBP | MYC binding protein | 0.00657129 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00656975 |
| NUTF2 | nuclear transport factor 2 | 0.00656245 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00655189 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00655105 |
| ATP5G1 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) | 0.00649866 |
| AURKA | aurora kinase A | 0.00648932 |
| C4BPA | complement component 4 binding protein, alpha | 0.00648717 |
| SSBP3 | single stranded DNA binding protein 3 | 0.00646924 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.00646255 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.00645645 |
| CRYL1 | crystallin, lambda 1 | 0.006445 |
| MRS2 | MRS2 magnesium transporter | 0.00643854 |
| GRAMD4 | GRAM domain containing 4 | 0.00643457 |
| CRYZ | crystallin, zeta (quinone reductase) | 0.00643187 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.0064214 |
| CLDND1 | claudin domain containing 1 | 0.00642021 |
| AOC1 | amine oxidase, copper containing 1 | 0.00641754 |
| TMEM126B | transmembrane protein 126B | 0.00640952 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00640746 |
| S100A8 | S100 calcium binding protein A8 | 0.0064049 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | 0.00640161 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00639136 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00636279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -0.0242315 |
| SFRP1 | secreted frizzled-related protein 1 | -0.019629 |
| MX1 | MX dynamin-like GTPase 1 | -0.0192289 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.017586 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0175622 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0167781 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0164952 |
| IFI44L | interferon-induced protein 44-like | -0.0163195 |
| SYNM | synemin, intermediate filament protein | -0.0160337 |
| OXTR | oxytocin receptor | -0.0160108 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0158303 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0157482 |
| FHL1 | four and a half LIM domains 1 | -0.0155496 |
| PEG3 | paternally expressed 3 | -0.0153457 |
| ANXA1 | annexin A1 | -0.0152296 |
| MMP7 | matrix metallopeptidase 7 | -0.0151426 |
| ABLIM1 | actin binding LIM protein 1 | -0.015131 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0150819 |
| MGP | matrix Gla protein | -0.0148786 |
| KRT7 | keratin 7, type II | -0.0147538 |
| PROM1 | prominin 1 | -0.0146892 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0145251 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.013876 |
| C3 | complement component 3 | -0.0138615 |
| LTF | lactotransferrin | -0.0137097 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0136037 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0135836 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0135278 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.013465 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0133479 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.0132387 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0131549 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0131098 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0130277 |
| TSPYL5 | TSPY-like 5 | -0.0127994 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0125231 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0123809 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0123504 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0123362 |
| CRYAB | crystallin, alpha B | -0.0123073 |
| IFI44 | interferon-induced protein 44 | -0.0122808 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0122441 |
| ZIC1 | Zic family member 1 | -0.0121997 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.0121706 |
| PALMD | palmdelphin | -0.0119673 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0118363 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.0117924 |
| NES | nestin | -0.0117156 |
| MYBPC1 | myosin binding protein C, slow type | -0.0116785 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0115694 |
| GPC3 | glypican 3 | -0.0115531 |
| CHRDL1 | chordin-like 1 | -0.0115274 |
| PDZD2 | PDZ domain containing 2 | -0.0115075 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0113164 |
| KRT23 | keratin 23, type I | -0.0113162 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0112972 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.0112593 |
| HLA-B | major histocompatibility complex, class I, B | -0.011219 |
| HOMER1 | homer scaffolding protein 1 | -0.0110987 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.0110238 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0109906 |
| NCAM1 | neural cell adhesion molecule 1 | -0.010747 |
| VWF | von Willebrand factor | -0.0107153 |
| SELL | selectin L | -0.0106787 |
| FAM107A | family with sequence similarity 107, member A | -0.0106342 |
| VLDLR | very low density lipoprotein receptor | -0.0106253 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.0106076 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0105934 |
| MFAP5 | microfibrillar associated protein 5 | -0.0105456 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0105068 |
| RGCC | regulator of cell cycle | -0.0104863 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0104253 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.0104114 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0103717 |
| MX2 | MX dynamin-like GTPase 2 | -0.0103488 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0102478 |
| BMP7 | bone morphogenetic protein 7 | -0.0102324 |
| MSLN | mesothelin | -0.0101842 |
| CES1 | carboxylesterase 1 | -0.0101668 |
| MEOX2 | mesenchyme homeobox 2 | -0.0101177 |
| SVIL | supervillin | -0.0101149 |
| TNNC1 | troponin C type 1 (slow) | -0.0101087 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0100575 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0100039 |
| LIPG | lipase, endothelial | -0.00997754 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00996213 |
| TAC1 | tachykinin, precursor 1 | -0.00995308 |
| ESR1 | estrogen receptor 1 | -0.0099382 |
| A2M | alpha-2-macroglobulin | -0.00990137 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00987173 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00982321 |
| PIP | prolactin-induced protein | -0.00981368 |
| GSDME | gasdermin E | -0.00978596 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00977936 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00971545 |
| CHI3L2 | chitinase 3-like 2 | -0.00971128 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00970782 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00970608 |
| MUC16 | mucin 16, cell surface associated | -0.0096594 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00964896 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00964577 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.00962219 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00960527 |
| PODXL | podocalyxin-like | -0.00955334 |
| FRY | furry homolog (Drosophila) | -0.00954976 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00951848 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00943956 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00941866 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00941739 |
| MVP | major vault protein | -0.0093929 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00934646 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00931433 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00926958 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00926944 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00924764 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.009247 |
| RRAGD | Ras-related GTP binding D | -0.00918229 |
| PDE8B | phosphodiesterase 8B | -0.00917864 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00914483 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00912339 |
| KRT14 | keratin 14, type I | -0.00906506 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00905092 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.00904836 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.0090466 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00903887 |
| TMEM100 | transmembrane protein 100 | -0.00897517 |
| GOLGA8A | golgin A8 family, member A | -0.00896896 |
| HLA-A | major histocompatibility complex, class I, A | -0.00895718 |
| BTG2 | BTG family, member 2 | -0.00895286 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00892701 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00888592 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00888242 |
| QKI | QKI, KH domain containing, RNA binding | -0.00879143 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00877828 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00877227 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0087105 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00870315 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00868645 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00867836 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00865586 |
| STK10 | serine/threonine kinase 10 | -0.00864728 |
| MED1 | mediator complex subunit 1 | -0.00859231 |
| SP100 | SP100 nuclear antigen | -0.0085519 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00852383 |
| FBLN5 | fibulin 5 | -0.00845177 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00844975 |
| HECA | headcase homolog (Drosophila) | -0.00844351 |
| IL1B | interleukin 1, beta | -0.00843908 |
| CD93 | CD93 molecule | -0.00842218 |
| JMJD1C | jumonji domain containing 1C | -0.0084046 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.0083894 |
| TMEM255A | transmembrane protein 255A | -0.00836761 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00836038 |
| IRS2 | insulin receptor substrate 2 | -0.00834326 |
| HRASLS | HRAS-like suppressor | -0.00833712 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00831942 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0083087 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0082604 |
| KLHL41 | kelch-like family member 41 | -0.0082258 |
| MYOZ2 | myozenin 2 | -0.0082204 |
| GPX7 | glutathione peroxidase 7 | -0.00818069 |
| ZNF91 | zinc finger protein 91 | -0.00817025 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00815 |
| NRCAM | neuronal cell adhesion molecule | -0.00812097 |
| PITX3 | paired-like homeodomain 3 | -0.00811876 |
| LAMC2 | laminin, gamma 2 | -0.00808244 |
| RGS5 | regulator of G-protein signaling 5 | -0.00806228 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00805832 |
| FGF9 | fibroblast growth factor 9 | -0.00804842 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00803287 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0080074 |
| KYNU | kynureninase | -0.00799556 |
| PITRM1 | pitrilysin metallopeptidase 1 | -0.00798643 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00797419 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00794982 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00792013 |
| BEX4 | brain expressed, X-linked 4 | -0.00791983 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.00791434 |
| TNS1 | tensin 1 | -0.00789815 |
| MYOF | myoferlin | -0.00788616 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00787547 |
| KRT15 | keratin 15, type I | -0.00781908 |
| FYCO1 | FYVE and coiled-coil domain containing 1 | -0.00780686 |
| IL6 | interleukin 6 | -0.00780294 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00780117 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00779022 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00778562 |
| TLR5 | toll-like receptor 5 | -0.00777189 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00775894 |
| MPDZ | multiple PDZ domain protein | -0.00773455 |
| FABP7 | fatty acid binding protein 7, brain | -0.00772656 |
| PRKCA | protein kinase C, alpha | -0.00771812 |
| NFIB | nuclear factor I/B | -0.00769005 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00767735 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00767447 |
| SAMHD1 | SAM domain and HD domain 1 | -0.00767084 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00767 |
| GOLGA8H | golgin A8 family, member H | -0.00766569 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00766073 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.0076546 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00764009 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.00762594 |
| MYO1C | myosin IC | -0.00761609 |
| SMPX | small muscle protein, X-linked | -0.00756481 |
| COG7 | component of oligomeric golgi complex 7 | -0.00756 |
| MAOB | monoamine oxidase B | -0.00754113 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | -0.00753241 |
| RBM34 | RNA binding motif protein 34 | -0.00751373 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.00749365 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00749341 |
| MGLL | monoglyceride lipase | -0.00748923 |
| RUNX1 | runt-related transcription factor 1 | -0.0074558 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00745139 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -0.00742526 |
| NID1 | nidogen 1 | -0.00739316 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00737531 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00736532 |
| SP110 | SP110 nuclear body protein | -0.00735668 |
| BCL2A1 | BCL2-related protein A1 | -0.00732905 |
| COPA | coatomer protein complex, subunit alpha | -0.00731128 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) | -0.00730724 |
| WIF1 | WNT inhibitory factor 1 | -0.00730065 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | -0.00728472 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00727854 |
| ERP44 | endoplasmic reticulum protein 44 | -0.00727314 |
| REEP1 | receptor accessory protein 1 | -0.00726473 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00725919 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00724514 |
| FZD10 | frizzled class receptor 10 | -0.00723865 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -0.00723814 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00722921 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00722549 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.0072117 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00721099 |
| B2M | beta-2-microglobulin | -0.0072083 |
| DES | desmin | -0.0072031 |
| TUBD1 | tubulin, delta 1 | -0.00719262 |
| GPX3 | glutathione peroxidase 3 | -0.00718726 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00717277 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00715178 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00715081 |
| CAPN6 | calpain 6 | -0.00712461 |
| DOK5 | docking protein 5 | -0.00711738 |
| C9ORF91 | chromosome 9 open reading frame 91 | -0.00711168 |
| TNC | tenascin C | -0.00710266 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00709632 |
| ANXA3 | annexin A3 | -0.00709103 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.00709003 |
| TLR7 | toll-like receptor 7 | -0.00708591 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00708341 |
