TET2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description tet methylcytosine dioxygenase 2|The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 54790)
External Link https://ncbi.nlm.nih.gov/gene/54790
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Genes

497 genes differentially expressed following the TET2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0214728
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0189325
GNAS GNAS complex locus 0.0168041
CXCL13 chemokine (C-X-C motif) ligand 13 0.0141814
GOLGA8A golgin A8 family, member A 0.0136164
MAGEA3 melanoma antigen family A3 0.0134285
SFRP1 secreted frizzled-related protein 1 0.0131824
BASP1 brain abundant, membrane attached signal protein 1 0.0130708
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.012996
COL4A5 collagen, type IV, alpha 5 0.0127196
IRS2 insulin receptor substrate 2 0.0126766
GREM1 gremlin 1, DAN family BMP antagonist 0.0125489
RHOBTB3 Rho-related BTB domain containing 3 0.0123669
LIMCH1 LIM and calponin homology domains 1 0.012035
PBX1 pre-B-cell leukemia homeobox 1 0.0119623
BST2 bone marrow stromal cell antigen 2 0.0119233
XIC X chromosome inactivation center 0.0118807
CXCL9 chemokine (C-X-C motif) ligand 9 0.011804
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0116196
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0112981
IFI44L interferon-induced protein 44-like 0.0112761
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0111442
TGM2 transglutaminase 2 0.0111273
CXCL10 chemokine (C-X-C motif) ligand 10 0.0107053
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.0105263
CHGB chromogranin B 0.0104575
VCL vinculin 0.0104446
RAD23B RAD23 homolog B (S. cerevisiae) 0.010346
GOLGA8H golgin A8 family, member H 0.0103147
GBP1 guanylate binding protein 1, interferon-inducible 0.0102179
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.0102149
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.0101443
MEIS2 Meis homeobox 2 0.0101157
PMP22 peripheral myelin protein 22 0.00999604
NBPF10 neuroblastoma breakpoint family, member 10 0.00997082
PBX3 pre-B-cell leukemia homeobox 3 0.00989481
ZBTB20 zinc finger and BTB domain containing 20 0.00986544
NAV2 neuron navigator 2 0.00983647
ADGRF5 adhesion G protein-coupled receptor F5 0.00973907
BCHE butyrylcholinesterase 0.00968091
TENT4A terminal nucleotidyltransferase 4A 0.00964771
RNF167 ring finger protein 167 0.00963668
KRT7 keratin 7, type II 0.00960398
SRRM2 serine/arginine repetitive matrix 2 0.00949391
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00942224
DMXL2 Dmx-like 2 0.00938374
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00933389
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00928543
CPE carboxypeptidase E 0.00922582
MN1 meningioma (disrupted in balanced translocation) 1 0.0092164
COL4A6 collagen, type IV, alpha 6 0.0091169
FAM120A family with sequence similarity 120A 0.00903549
SIDT2 SID1 transmembrane family, member 2 0.00898536
CSAD cysteine sulfinic acid decarboxylase 0.00897203
ZEB1 zinc finger E-box binding homeobox 1 0.0089217
CLC Charcot-Leyden crystal galectin 0.00890454
ISG15 ISG15 ubiquitin-like modifier 0.00887265
PDGFC platelet derived growth factor C 0.0087733
MAP7 microtubule-associated protein 7 0.00875875
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00874296
TBX3 T-box 3 0.00869627
DUSP5 dual specificity phosphatase 5 0.00868804
IFI44 interferon-induced protein 44 0.00867869
BRD4 bromodomain containing 4 0.00861239
HK1 hexokinase 1 0.00857527
TLN1 talin 1 0.00853501
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00852837
PLXNB2 plexin B2 0.00852438
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00850404
DPYD dihydropyrimidine dehydrogenase 0.00847291
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00846121
KANK2 KN motif and ankyrin repeat domains 2 0.00842544
NELL1 NEL-like 1 (chicken) 0.00837567
OSBPL10 oxysterol binding protein-like 10 0.00836862
SOBP sine oculis binding protein homolog (Drosophila) 0.00835029
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00830341
JCHAIN joining chain of multimeric IgA and IgM 0.00829922
CCDC47 coiled-coil domain containing 47 0.0082874
JMJD6 jumonji domain containing 6 0.00824604
CRISP3 cysteine-rich secretory protein 3 0.00815598
RUBCN rubicon autophagy regulator 0.00810896
ZNF512B zinc finger protein 512B 0.00809709
CXCL11 chemokine (C-X-C motif) ligand 11 0.00804261
SGK1 serum/glucocorticoid regulated kinase 1 0.00804146
IGSF3 immunoglobulin superfamily, member 3 0.00803479
ADCY9 adenylate cyclase 9 0.00802573
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00801461
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.0079783
ZSWIM8 zinc finger, SWIM-type containing 8 0.00795841
LAMA5 laminin, alpha 5 0.00789215
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0078472
PNISR PNN-interacting serine/arginine-rich protein 0.00784668
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00781734
PDE10A phosphodiesterase 10A 0.00780702
CCL8 chemokine (C-C motif) ligand 8 0.00778389
LY6E lymphocyte antigen 6 complex, locus E 0.00772683
LUM lumican 0.00768722
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00766259
HHEX hematopoietically expressed homeobox 0.00766061
EDNRA endothelin receptor type A 0.00764693
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00764502
AHCYL1 adenosylhomocysteinase-like 1 0.00763185
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.00762835
CCNL2 cyclin L2 0.00761636
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00760135
SPG11 spastic paraplegia 11 (autosomal recessive) 0.00758519
PALLD palladin, cytoskeletal associated protein 0.00758493
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00753607
CHD9 chromodomain helicase DNA binding protein 9 0.00752672
PON3 paraoxonase 3 0.00751687
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00750865
PDLIM7 PDZ and LIM domain 7 (enigma) 0.00750157
TLE4 transducin-like enhancer of split 4 0.00749778
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00747038
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0074533
G6PD glucose-6-phosphate dehydrogenase 0.0073978
MSL1 male-specific lethal 1 homolog (Drosophila) 0.00738027
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00736894
CDA cytidine deaminase 0.0073491
CLGN calmegin 0.00730373
ZFP36L1 ZFP36 ring finger protein-like 1 0.007298
FASN fatty acid synthase 0.00727556
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0072728
CA11 carbonic anhydrase XI 0.00724896
ZMIZ1 zinc finger, MIZ-type containing 1 0.00724592
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00724451
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00723503
FLT1 fms-related tyrosine kinase 1 0.00722966
IL13RA2 interleukin 13 receptor, alpha 2 0.0072207
KPNB1 karyopherin (importin) beta 1 0.00719332
PDE8B phosphodiesterase 8B 0.00718957
SETD5 SET domain containing 5 0.00717582
FLNA filamin A, alpha 0.00717471
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00716891
NBEA neurobeachin 0.00716559
PDIA3 protein disulfide isomerase family A, member 3 0.00714968
NFIB nuclear factor I/B 0.00714856
TMSB15A thymosin beta 15a 0.0071137
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00709423
ZNF638 zinc finger protein 638 0.00708946
TBL1X transducin (beta)-like 1X-linked 0.00708805
VEGFA vascular endothelial growth factor A 0.00706295
XAF1 XIAP associated factor 1 0.00705832
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00705017
LYPD3 LY6/PLAUR domain containing 3 0.00704473
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.00703118
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.0070299
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00702814
CUX1 cut-like homeobox 1 0.00702664
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.00702408
HIRA histone cell cycle regulator 0.00699415
DVL1 dishevelled segment polarity protein 1 0.00698967
PILRB paired immunoglobin-like type 2 receptor beta 0.00696593
NPTN neuroplastin 0.00696456
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.00696289
WWC3 WWC family member 3 0.00694744
TGFB1 transforming growth factor, beta 1 0.00691966
RTN2 reticulon 2 0.0069163
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00691049
SLC35E2B solute carrier family 35, member E2B 0.00690653
CD83 CD83 molecule 0.00689563
EIF3B eukaryotic translation initiation factor 3, subunit B 0.00688625
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00685889
MX1 MX dynamin-like GTPase 1 0.0068472
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00683691
NDNF neuron-derived neurotrophic factor 0.00682832
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00678401
DYNLL1 dynein, light chain, LC8-type 1 0.00678008
ECHDC2 enoyl CoA hydratase domain containing 2 0.0067742
FNBP1 formin binding protein 1 0.0067517
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.00674684
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.00673181
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00673087
COL9A2 collagen, type IX, alpha 2 0.00672912
SRSF4 serine/arginine-rich splicing factor 4 0.00667372
GLS glutaminase 0.00666833
DGKD diacylglycerol kinase, delta 130kDa 0.00666466
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.00666374
TNIK TRAF2 and NCK interacting kinase 0.00665324
EXOC7 exocyst complex component 7 0.0066341
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00661298
RBM26 RNA binding motif protein 26 0.00660711
LPP LIM domain containing preferred translocation partner in lipoma 0.0065969
CKAP4 cytoskeleton-associated protein 4 0.00659561
SCPEP1 serine carboxypeptidase 1 0.0065823
BTBD3 BTB (POZ) domain containing 3 0.00656367
RGS5 regulator of G-protein signaling 5 0.00656021
SVIL supervillin 0.00656012
CPB1 carboxypeptidase B1 (tissue) 0.00655336
EXT1 exostosin glycosyltransferase 1 0.00654869
NLRP2 NLR family, pyrin domain containing 2 0.0065478
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0065276
GALC galactosylceramidase 0.00652096
STX16 syntaxin 16 0.00651921
GOLM1 golgi membrane protein 1 0.00651182
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00650733
ADGRL2 adhesion G protein-coupled receptor L2 0.00650361
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.00650064
HMG20B high mobility group 20B 0.00649172
WSB1 WD repeat and SOCS box containing 1 0.00645856
LAMP3 lysosomal-associated membrane protein 3 0.00644866
MLPH melanophilin 0.00644486
NINL ninein-like 0.00644227
CADM1 cell adhesion molecule 1 0.00642497
TUG1 taurine up-regulated 1 (non-protein coding) 0.00641849
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00641601
TNS1 tensin 1 0.00639551
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00638723
ORC1 origin recognition complex, subunit 1 0.00638415
SAMD4A sterile alpha motif domain containing 4A 0.00636758
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00636044
GANAB glucosidase, alpha; neutral AB 0.00634604
AIM2 absent in melanoma 2 0.00634493
PRUNE2 prune homolog 2 (Drosophila) 0.0063383
PCP4 Purkinje cell protein 4 0.0063258
SPEN spen family transcriptional repressor 0.00632527
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00632416
DMPK dystrophia myotonica-protein kinase 0.00632273
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00631133
AMIGO2 adhesion molecule with Ig-like domain 2 0.00631103
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.00631084
RUFY3 RUN and FYVE domain containing 3 0.00630941
RSAD2 radical S-adenosyl methionine domain containing 2 0.00630766
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00630752
MACF1 microtubule-actin crosslinking factor 1 0.00630379
ZDHHC6 zinc finger, DHHC-type containing 6 0.00628148
MYLK myosin light chain kinase 0.00628103
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.00626809
NXN nucleoredoxin 0.00626315
ADARB1 adenosine deaminase, RNA-specific, B1 0.00625536
FGL2 fibrinogen-like 2 0.00625331
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.00625285
UNC13B unc-13 homolog B (C. elegans) 0.00624403
ZNF160 zinc finger protein 160 0.00624225
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0062255
GRB10 growth factor receptor-bound protein 10 0.00622519
CCDC86 coiled-coil domain containing 86 0.00621675
ACADVL acyl-CoA dehydrogenase, very long chain 0.00621521
SNX1 sorting nexin 1 0.00619452
HAUS3 HAUS augmin-like complex, subunit 3 0.00618957
GSDME gasdermin E 0.00618812
RHOF ras homolog family member F (in filopodia) 0.00618535
KDR kinase insert domain receptor 0.00618239
ARHGAP6 Rho GTPase activating protein 6 0.0061811
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00618056
SIK1 salt-inducible kinase 1 0.00617234
NEMP1 nuclear envelope integral membrane protein 1 0.00616937
RASIP1 Ras interacting protein 1 0.00615985
UBP1 upstream binding protein 1 (LBP-1a) 0.00615889

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0241798
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.0148125
CEMIP cell migration inducing protein, hyaluronan binding -0.0143251
SCGB2A1 secretoglobin, family 2A, member 1 -0.0133037
TFF3 trefoil factor 3 (intestinal) -0.0128959
S100A10 S100 calcium binding protein A10 -0.0123914
GPX2 glutathione peroxidase 2 -0.0123847
PUF60 poly-U binding splicing factor 60KDa -0.0121467
TUBB2A tubulin, beta 2A class IIa -0.0117237
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.0113757
GMDS GDP-mannose 4,6-dehydratase -0.0113469
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0109593
LGALS4 lectin, galactoside-binding, soluble, 4 -0.0109543
SEPP1 selenoprotein P, plasma, 1 -0.0107043
BAMBI BMP and activin membrane-bound inhibitor -0.0104257
PKP2 plakophilin 2 -0.0103739
LGALS3 lectin, galactoside-binding, soluble, 3 -0.010265
ASRGL1 asparaginase like 1 -0.0102491
AKR1C3 aldo-keto reductase family 1, member C3 -0.0101106
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0100588
DSP desmoplakin -0.00995038
CD9 CD9 molecule -0.00989861
COQ8A coenzyme Q8A -0.00983346
GSTO1 glutathione S-transferase omega 1 -0.00976596
PI3 peptidase inhibitor 3, skin-derived -0.00969072
ITM2C integral membrane protein 2C -0.00967359
CRIP1 cysteine-rich protein 1 (intestinal) -0.00963669
WFDC2 WAP four-disulfide core domain 2 -0.00954125
TXNDC9 thioredoxin domain containing 9 -0.00952479
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00940608
RCAN1 regulator of calcineurin 1 -0.00938388
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00933609
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00933549
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00928184
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00925851
EMP1 epithelial membrane protein 1 -0.00925573
HTRA1 HtrA serine peptidase 1 -0.00914464
LSM1 LSM1, U6 small nuclear RNA associated -0.00912824
MAL mal, T-cell differentiation protein -0.00912055
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -0.00902766
CSTA cystatin A (stefin A) -0.0089947
ADAM28 ADAM metallopeptidase domain 28 -0.00890873
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.00882414
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00877196
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00877184
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00872933
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00872661
LEFTY1 left-right determination factor 1 -0.00868201
IFITM2 interferon induced transmembrane protein 2 -0.00867454
FAR2 fatty acyl CoA reductase 2 -0.00861487
CCL20 chemokine (C-C motif) ligand 20 -0.00860633
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00852989
KRT20 keratin 20, type I -0.00851366
RGS10 regulator of G-protein signaling 10 -0.00844256
EMX2 empty spiracles homeobox 2 -0.00840274
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00834781
CLDN10 claudin 10 -0.00831761
IL1R2 interleukin 1 receptor, type II -0.00826857
AREG amphiregulin -0.00823315
ECI2 enoyl-CoA delta isomerase 2 -0.00821689
CYBA cytochrome b-245, alpha polypeptide -0.00821097
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00821095
RNASET2 ribonuclease T2 -0.00819854
SLPI secretory leukocyte peptidase inhibitor -0.00814167
HSBP1 heat shock factor binding protein 1 -0.00813446
HBB hemoglobin, beta -0.00809104
TSPAN8 tetraspanin 8 -0.0080695
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00805907
TRAPPC2L trafficking protein particle complex 2-like -0.00804236
TRH thyrotropin-releasing hormone -0.00800312
VSNL1 visinin-like 1 -0.00798768
EPCAM epithelial cell adhesion molecule -0.0079796
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -0.0079526
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00791717
CYB5A cytochrome b5 type A (microsomal) -0.00780065
TSPAN1 tetraspanin 1 -0.00772135
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00771856
PERP PERP, TP53 apoptosis effector -0.00771804
MECOM MDS1 and EVI1 complex locus -0.00771041
THBS2 thrombospondin 2 -0.00770989
C3 complement component 3 -0.00770846
SPON1 spondin 1, extracellular matrix protein -0.00769005
KLK10 kallikrein-related peptidase 10 -0.00767812
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00765183
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00760016
VAMP5 vesicle-associated membrane protein 5 -0.007599
DOK5 docking protein 5 -0.00747933
S100A2 S100 calcium binding protein A2 -0.00747753
MRPL48 mitochondrial ribosomal protein L48 -0.00743224
SOX17 SRY (sex determining region Y)-box 17 -0.00742831
POLB polymerase (DNA directed), beta -0.00740849
SMYD2 SET and MYND domain containing 2 -0.00740476
DMAC2L distal membrane arm assembly component 2 like -0.00739605
AOC1 amine oxidase, copper containing 1 -0.00737372
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00734895
SELENOW selenoprotein W -0.00731402
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00728454
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00728327
SIRT5 sirtuin 5 -0.00727412
TMEM14A transmembrane protein 14A -0.00726974
C6ORF48 chromosome 6 open reading frame 48 -0.00726797
MLF1 myeloid leukemia factor 1 -0.00725074
GLUL glutamate-ammonia ligase -0.00724471
ANXA2P2 annexin A2 pseudogene 2 -0.00722249
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00718284
CASP4 caspase 4, apoptosis-related cysteine peptidase -0.00717507
PMP2 peripheral myelin protein 2 -0.00716903
TMEM231 transmembrane protein 231 -0.00713868
FERMT1 fermitin family member 1 -0.00712643
CLTB clathrin, light chain B -0.00710023
GLDC glycine dehydrogenase (decarboxylating) -0.00708902
OSTF1 osteoclast stimulating factor 1 -0.00708492
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00707237
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0070592
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00701156
SMAGP small cell adhesion glycoprotein -0.00700914
S100A8 S100 calcium binding protein A8 -0.00699398
GCA grancalcin, EF-hand calcium binding protein -0.00698387
AMDHD2 amidohydrolase domain containing 2 -0.0069828
KRT23 keratin 23, type I -0.00697152
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -0.00697093
FABP1 fatty acid binding protein 1, liver -0.00694909
SATB2 SATB homeobox 2 -0.00692825
KRT5 keratin 5, type II -0.00692807
TMEM14B transmembrane protein 14B -0.00689619
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.00689328
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00687001
TMEM176A transmembrane protein 176A -0.00684756
CLU clusterin -0.00682997
DEFB1 defensin, beta 1 -0.00682057
PITX3 paired-like homeodomain 3 -0.00681966
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00679684
EAPP E2F-associated phosphoprotein -0.00677642
CETN2 centrin, EF-hand protein, 2 -0.00676958
TCTN2 tectonic family member 2 -0.00674276
SAR1B secretion associated, Ras related GTPase 1B -0.00672836
MRPS18A mitochondrial ribosomal protein S18A -0.00672397
AZIN1 antizyme inhibitor 1 -0.00670847
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00669575
VIL1 villin 1 -0.00668938
MYL12B myosin, light chain 12B, regulatory -0.00668864
DEF8 differentially expressed in FDCP 8 homolog (mouse) -0.00666788
MED7 mediator complex subunit 7 -0.00665494
ANAPC15 anaphase promoting complex subunit 15 -0.00665479
CALML4 calmodulin-like 4 -0.0066376
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00662789
AK4 adenylate kinase 4 -0.00661164
ZNF552 zinc finger protein 552 -0.00660782
SCRG1 stimulator of chondrogenesis 1 -0.00659976
TANK TRAF family member-associated NFKB activator -0.00659359
CDC123 cell division cycle 123 -0.00657212
NPC2 Niemann-Pick disease, type C2 -0.00656919
RPS5 ribosomal protein S5 -0.00656436
BPGM 2,3-bisphosphoglycerate mutase -0.00654464
SIVA1 SIVA1, apoptosis-inducing factor -0.0065395
FOXG1 forkhead box G1 -0.00653526
MRPL23 mitochondrial ribosomal protein L23 -0.00653465
MAP1A microtubule-associated protein 1A -0.00651148
THBS1 thrombospondin 1 -0.0064938
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00648341
MED6 mediator complex subunit 6 -0.00647798
RPA3 replication protein A3, 14kDa -0.00647057
PLLP plasmolipin -0.00646347
CRIPT cysteine-rich PDZ-binding protein -0.00644857
NT5E 5'-nucleotidase, ecto (CD73) -0.00644218
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00642457
ARHGAP26 Rho GTPase activating protein 26 -0.00642431
DLK1 delta-like 1 homolog (Drosophila) -0.00641676
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00641008
CYC1 cytochrome c-1 -0.00638882
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00638291
ZNF277 zinc finger protein 277 -0.00638215
AHSG alpha-2-HS-glycoprotein -0.00635695
SPA17 sperm autoantigenic protein 17 -0.00634938
CCN2 cellular communication network factor 2 -0.00634247
ADAP1 ArfGAP with dual PH domains 1 -0.00631972
COMMD8 COMM domain containing 8 -0.00631631
S100B S100 calcium binding protein B -0.00630089
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -0.00629837
SYBU syntabulin (syntaxin-interacting) -0.00629745
PYCARD PYD and CARD domain containing -0.00627678
EIF4A3 eukaryotic translation initiation factor 4A3 -0.00626278
IFT52 intraflagellar transport 52 -0.00624333
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00623933
GPA33 glycoprotein A33 (transmembrane) -0.00623925
APOA2 apolipoprotein A-II -0.00623746
HIST3H2A histone cluster 3, H2a -0.00623546
STMN2 stathmin 2 -0.00622813
PRKCQ protein kinase C, theta -0.00621791
FGGY FGGY carbohydrate kinase domain containing -0.00620622
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00619815
STK17A serine/threonine kinase 17a -0.00619625
CLIC1 chloride intracellular channel 1 -0.00619606
TTC1 tetratricopeptide repeat domain 1 -0.00618692
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00618109
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00616147
LYRM4 LYR motif containing 4 -0.00615537
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00615111
CSTB cystatin B (stefin B) -0.00613824
S100A9 S100 calcium binding protein A9 -0.00612966
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.00610203
COMMD3 COMM domain containing 3 -0.00609395
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00608105
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00607864
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00607648
COMMD10 COMM domain containing 10 -0.00607626
COPS8 COP9 signalosome subunit 8 -0.00603143
METTL18 methyltransferase like 18 -0.0060273
LIPT1 lipoyltransferase 1 -0.00602105
MPP1 membrane protein, palmitoylated 1, 55kDa -0.00601997
SYNGR3 synaptogyrin 3 -0.00601764
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00600991
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00600837
TXNL1 thioredoxin-like 1 -0.00598771
HEBP2 heme binding protein 2 -0.00597802
AAMDC adipogenesis associated, Mth938 domain containing -0.00595775
MRPS33 mitochondrial ribosomal protein S33 -0.00595653
CGRRF1 cell growth regulator with ring finger domain 1 -0.00595024
TXN thioredoxin -0.00594725
IFT20 intraflagellar transport 20 -0.00594223
LRRC17 leucine rich repeat containing 17 -0.0059356
CD59 CD59 molecule, complement regulatory protein -0.00593018
MRPL39 mitochondrial ribosomal protein L39 -0.00592832
PEX2 peroxisomal biogenesis factor 2 -0.00592734
SUMO3 small ubiquitin-like modifier 3 -0.00592506
PGGT1B protein geranylgeranyltransferase type I, beta subunit -0.00592084
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00591287
LASP1 LIM and SH3 protein 1 -0.00591069
CLIC5 chloride intracellular channel 5 -0.00590871
RBM7 RNA binding motif protein 7 -0.00589795
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.00589664
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -0.0058964
FAM171A1 family with sequence similarity 171, member A1 -0.0058804
ATF3 activating transcription factor 3 -0.00587831
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 -0.00587473
PLP1 proteolipid protein 1 -0.00586505
AMBP alpha-1-microglobulin/bikunin precursor -0.00586363
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00584435
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -0.00581968
RLN1 relaxin 1 -0.00581698
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00581558
RPL14 ribosomal protein L14 -0.00581062
COMMD9 COMM domain containing 9 -0.00580638
C9ORF16 chromosome 9 open reading frame 16 -0.00579522
NUTF2 nuclear transport factor 2 -0.00578884
CHMP6 charged multivesicular body protein 6 -0.00578544
RPL35 ribosomal protein L35 -0.00578472
MRS2 MRS2 magnesium transporter -0.00578206