TET3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description tet methylcytosine dioxygenase 3|Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM, Nov 2010] (NCBI Entrez Gene Database, 200424)
Similar Terms
Downloads & Tools

Genes

340 genes differentially expressed following the TET3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FPR3 formyl peptide receptor 3 3.37345
TSGA13 testis specific, 13 3.37345
OR2A42 olfactory receptor, family 2, subfamily A, member 42 3.37345
TNNI1 troponin I type 1 (skeletal, slow) 3.37345
MILR1 mast cell immunoglobulin-like receptor 1 3.37345
GRXCR2 glutaredoxin, cysteine rich 2 3.37345
TBX15 T-box 15 3.37345
GJB1 gap junction protein, beta 1, 32kDa 3.37345
SLC15A5 solute carrier family 15, member 5 3.37345
PLCH2 phospholipase C, eta 2 3.37345
NANOS3 nanos homolog 3 (Drosophila) 3.37345
CABP4 calcium binding protein 4 3.37345
ANKRD29 ankyrin repeat domain 29 3.37345
NRN1 neuritin 1 3.37345
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 3.37345
SIX6 SIX homeobox 6 3.37345
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.37345
CLEC12A C-type lectin domain family 12, member A 3.37345
FGF22 fibroblast growth factor 22 3.37345
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.37345
ZNF492 zinc finger protein 492 3.37345
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 3.37345
FBLN7 fibulin 7 3.37345
UNC45B unc-45 homolog B (C. elegans) 3.37345
GADL1 glutamate decarboxylase-like 1 3.37345
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.37345
ETV7 ets variant 7 3.37345
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 3.37345
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 3.37345
WAS Wiskott-Aldrich syndrome 3.37345
HIGD1C HIG1 hypoxia inducible domain family, member 1C 3.37345
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 3.37345
ANXA2R annexin A2 receptor 3.37345
PSD4 pleckstrin and Sec7 domain containing 4 3.37345
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3.37345
CPLX3 complexin 3 3.37345
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 3.37345
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 3.37345
TDRD9 tudor domain containing 9 3.37345
LRRC10B leucine rich repeat containing 10B 3.37345
ACVRL1 activin A receptor type II-like 1 3.37345
FOXJ1 forkhead box J1 3.37345
MUC20 mucin 20, cell surface associated 3.37345
MUC22 mucin 22 3.37345
NT5E 5'-nucleotidase, ecto (CD73) 3.37345
IL2RA interleukin 2 receptor, alpha 3.37345
CD34 CD34 molecule 3.37345
PCDHA2 protocadherin alpha 2 3.37345
LOC107986837 uncharacterized LOC107986837 3.37345
CLDN14 claudin 14 3.37345
GPR34 G protein-coupled receptor 34 3.37345
UNC5CL unc-5 homolog C (C. elegans)-like 3.37345
DNAAF1 dynein, axonemal, assembly factor 1 3.37345
SRGN serglycin 3.37345
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 3.37345
IQCF1 IQ motif containing F1 3.37345
GC group-specific component (vitamin D binding protein) 3.37345
WNT16 wingless-type MMTV integration site family, member 16 3.37345
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 3.37345
MCHR1 melanin-concentrating hormone receptor 1 3.37345
GBP4 guanylate binding protein 4 3.37345
CTXND1 cortexin domain containing 1 3.37345
LHFPL7 LHFPL tetraspan subfamily member 7 3.37345
H2BW2 H2B.W histone 2 3.37345
H1-8 H1.8 linker histone 3.37345
DUSP29 dual specificity phosphatase 29 3.37345
SPACDR sperm acrosome developmental regulator 3.37345
H1-6 H1.6 linker histone, cluster member 3.37345
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 3.37345
SPATS1 spermatogenesis associated, serine-rich 1 3.37345
GPR37L1 G protein-coupled receptor 37 like 1 3.37345
C15ORF62 chromosome 15 open reading frame 62 3.37345
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.37345
TFEC transcription factor EC 3.37345
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.37345
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 3.37345
TMEM236 transmembrane protein 236 3.37345
UROC1 urocanate hydratase 1 3.37345
IDO2 indoleamine 2,3-dioxygenase 2 3.37345
SP140 SP140 nuclear body protein 3.37345
VIT vitrin 3.37345
CFAP99 cilia and flagella associated protein 99 3.37345
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.37345
PGC progastricsin (pepsinogen C) 3.37345
C1QL4 complement component 1, q subcomponent-like 4 3.37345
GATA5 GATA binding protein 5 3.37345
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.37345
SAMD11 sterile alpha motif domain containing 11 3.37345
C7 complement component 7 3.37345
TACR2 tachykinin receptor 2 3.37345
CNTFR ciliary neurotrophic factor receptor 3.37345
SPDYE16 speedy/RINGO cell cycle regulator family member E16 3.37345
C6ORF118 chromosome 6 open reading frame 118 3.37345
KCNT1 potassium channel, sodium activated subfamily T, member 1 3.37345
TLE6 transducin-like enhancer of split 6 3.37345
RDH16 retinol dehydrogenase 16 (all-trans) 3.37345
TMEM132D transmembrane protein 132D 3.37345
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.37345
ERICH6B glutamate-rich 6B 3.37345
INHA inhibin, alpha 3.37345
AKNAD1 AKNA domain containing 1 3.37345
IL36R interleukin 36 receptor 3.37345
TTC9B tetratricopeptide repeat domain 9B 3.37345
IL11 interleukin 11 3.37345
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.37345
ZCCHC12 zinc finger, CCHC domain containing 12 3.37345
PLA1A phospholipase A1 member A 3.37345
IL21R interleukin 21 receptor 3.37345
CDHR4 cadherin-related family member 4 3.37345
VWA7 von Willebrand factor A domain containing 7 3.37345
AKR1B15 aldo-keto reductase family 1, member B15 3.37345
RGS11 regulator of G-protein signaling 11 3.37345
LCT lactase 3.37345
POF1B premature ovarian failure, 1B 3.37345
DQX1 DEAQ box RNA-dependent ATPase 1 3.37345
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 3.37345
KLHL1 kelch-like family member 1 3.37345
PHGR1 proline/histidine/glycine-rich 1 3.37345
NOX1 NADPH oxidase 1 3.37345
KLK7 kallikrein-related peptidase 7 3.37345
ILDR2 immunoglobulin-like domain containing receptor 2 3.37345
GPR150 G protein-coupled receptor 150 3.37345
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.37345
PCDHAC1 protocadherin alpha subfamily C, 1 3.37345
C4B complement component 4B (Chido blood group) 3.37345
ZBTB7C zinc finger and BTB domain containing 7C 3.37345
WNT4 wingless-type MMTV integration site family, member 4 3.37345
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 3.37345
ADRA2A adrenoceptor alpha 2A 3.37345
GOLGA8N golgin A8 family, member N 3.37345
NLRP14 NLR family, pyrin domain containing 14 3.37345
NMBR neuromedin B receptor 3.37345
TMPPE transmembrane protein with metallophosphoesterase domain 3.37345
IL9R interleukin 9 receptor 3.37345
CRYBA1 crystallin, beta A1 3.37345
NT5DC4 5'-nucleotidase domain containing 4 3.37345
ACSBG2 acyl-CoA synthetase bubblegum family member 2 3.37345
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 3.37345
PLAC8 placenta-specific 8 3.37345
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 3.37345
DAW1 dynein assembly factor with WDR repeat domains 1 3.37345
PGR progesterone receptor 3.37345
CISH cytokine inducible SH2-containing protein 3.37345
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 3.37345
CCL21 chemokine (C-C motif) ligand 21 3.37345
MPZL2 myelin protein zero-like 2 3.37345
MT1A metallothionein 1A 3.37345
MST1 macrophage stimulating 1 3.37345
TTC36 tetratricopeptide repeat domain 36 3.37345
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 3.37345
IL17B interleukin 17B 3.37345
CARD9 caspase recruitment domain family, member 9 3.37345
ANKRD33 ankyrin repeat domain 33 3.37345
ZMYND10 zinc finger, MYND-type containing 10 3.37345
ZNF823 zinc finger protein 823 3.37345
GGN gametogenetin 3.37345
DNAH8 dynein, axonemal, heavy chain 8 3.37345
PTGDR prostaglandin D2 receptor (DP) 3.37345
FGF17 fibroblast growth factor 17 3.37345
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 3.37345
FNDC1 fibronectin type III domain containing 1 3.37345
WNK4 WNK lysine deficient protein kinase 4 3.37345
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.37345
CD86 CD86 molecule 3.37345
TRPM1 transient receptor potential cation channel, subfamily M, member 1 3.37345
ASCL3 achaete-scute family bHLH transcription factor 3 3.37345
PTPN7 protein tyrosine phosphatase, non-receptor type 7 3.37345
NPPA natriuretic peptide A 3.37345
FGF14 fibroblast growth factor 14 3.30965
CRYZL2P-SEC16B CRYZL2P-SEC16B readthrough 3.22501
CLCN1 chloride channel, voltage-sensitive 1 3.22501
TRDN triadin 3.22501
SMG7 SMG7 nonsense mediated mRNA decay factor 3.0085
AKR1E2 aldo-keto reductase family 1, member E2 2.79428
MXRA8 matrix-remodelling associated 8 2.78181
MYOF myoferlin 2.76452
NRL neural retina leucine zipper 2.68418
OMG oligodendrocyte myelin glycoprotein 2.6748
ZNF763 zinc finger protein 763 2.6748
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 2.64351
ANTXR1 anthrax toxin receptor 1 2.63272
ARSA arylsulfatase A 2.60764
LIG4 ligase IV, DNA, ATP-dependent 2.59722
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.48118
ATN1 atrophin 1 2.47987
TUBGCP4 tubulin, gamma complex associated protein 4 2.43375
MAPK10 mitogen-activated protein kinase 10 2.42102
BTN2A2 butyrophilin, subfamily 2, member A2 2.41358
CFAP45 cilia and flagella associated protein 45 2.37723
NOD2 nucleotide-binding oligomerization domain containing 2 2.37723
SCN1B sodium channel, voltage gated, type I beta subunit 2.36834
TP53BP1 tumor protein p53 binding protein 1 2.3486
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 2.33988
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 2.33096
MORN4 MORN repeat containing 4 2.2944
ZNF8 zinc finger protein 8 2.28641
LRRTM1 leucine rich repeat transmembrane neuronal 1 2.19659
ARID5B AT rich interactive domain 5B (MRF1-like) 2.19659
STK38L serine/threonine kinase 38 like 2.19659
AHNAK2 AHNAK nucleoprotein 2 2.19659
MYO18B myosin XVIIIB 2.19659
HES4 hes family bHLH transcription factor 4 2.19659
RAD51 RAD51 recombinase 2.15215
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2.13955
RINL Ras and Rab interactor-like 2.1334
CCDC200 coiled-coil domain containing 200 2.13236
REST RE1-silencing transcription factor 2.13236
TIGD6 tigger transposable element derived 6 2.13003
CIBAR1 CBY1 interacting BAR domain containing 1 2.12302
ADD2 adducin 2 (beta) 2.11589
DNAAF2 dynein, axonemal, assembly factor 2 2.11503
THAP3 THAP domain containing, apoptosis associated protein 3 2.11503
TMEM245 transmembrane protein 245 2.11154
BAK1 BCL2-antagonist/killer 1 2.10794
LDHA lactate dehydrogenase A 2.0935
CEP63 centrosomal protein 63kDa 2.0855
TNRC6C trinucleotide repeat containing 6C 2.0855
CSKMT citrate synthase lysine methyltransferase 2.07304
NUB1 negative regulator of ubiquitin-like proteins 1 2.06524
EHD4 EH-domain containing 4 2.06365
MTMR9 myotubularin related protein 9 2.05254
GRIA4 glutamate receptor, ionotropic, AMPA 4 2.04227
WDR76 WD repeat domain 76 2.04227
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.04227
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.0377
HSBP1 heat shock factor binding protein 1 2.01906
KLHL8 kelch-like family member 8 2.00437
MYH9 myosin, heavy chain 9, non-muscle 2.00168
EMC6 ER membrane protein complex subunit 6 2.00113

decreased expression

Symbol Name Standardized Value
NR1I2 nuclear receptor subfamily 1, group I, member 2 -3.37345
AMDHD1 amidohydrolase domain containing 1 -3.37345
CA7 carbonic anhydrase VII -3.37345
BAIAP3 BAI1-associated protein 3 -3.37345
GCK glucokinase (hexokinase 4) -3.37345
TTLL10 tubulin tyrosine ligase-like family member 10 -3.37345
TMEM191C transmembrane protein 191C -3.37345
DUSP8 dual specificity phosphatase 8 -3.37345
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -3.37345
BAAT bile acid CoA:amino acid N-acyltransferase -3.37345
KCTD11 potassium channel tetramerization domain containing 11 -3.37345
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -3.37345
TP53TG5 TP53 target 5 -3.37345
SPAG6 sperm associated antigen 6 -3.37345
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A -3.37345
CYSRT1 cysteine-rich tail protein 1 -3.37345
ASIC4 acid sensing (proton gated) ion channel family member 4 -3.37345
COL6A6 collagen, type VI, alpha 6 -3.37345
ZNF688 zinc finger protein 688 -3.37345
WSCD2 WSC domain containing 2 -3.37345
BTN3A3 butyrophilin, subfamily 3, member A3 -3.37345
PCDH19 protocadherin 19 -3.37345
RGS9 regulator of G-protein signaling 9 -3.37345
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) -3.37345
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -3.37345
LOXHD1 lipoxygenase homology domains 1 -3.37345
PPP1R21 protein phosphatase 1, regulatory subunit 21 -3.37345
H4C5 H4 clustered histone 5 -3.37345
KLHL10 kelch-like family member 10 -3.37345
CLUL1 clusterin-like 1 (retinal) -3.37345
BCL6 B-cell CLL/lymphoma 6 -3.37345
PWWP3B PWWP domain containing 3B -3.37345
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -3.37345
HK2 hexokinase 2 -3.37345
ACKR3 atypical chemokine receptor 3 -3.37345
RAN RAN, member RAS oncogene family -3.37345
MAT1A methionine adenosyltransferase I, alpha -3.37345
EPHA3 EPH receptor A3 -3.37345
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic -3.37345
SDS serine dehydratase -3.37345
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -3.34484
ZNF888 zinc finger protein 888 -3.33959
RASIP1 Ras interacting protein 1 -3.33959
BRME1 break repair meiotic recombinase recruitment factor 1 -3.27999
RNF207 ring finger protein 207 -3.27999
MFAP3L microfibrillar-associated protein 3-like -3.26612
ZNF454 zinc finger protein 454 -3.25314
AGBL5 ATP/GTP binding protein-like 5 -3.10699
RHOF ras homolog family member F (in filopodia) -3.08326
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -3.03937
EIF3M eukaryotic translation initiation factor 3, subunit M -2.98761
MRPS35 mitochondrial ribosomal protein S35 -2.85009
NOP56 NOP56 ribonucleoprotein -2.75311
FTCD formimidoyltransferase cyclodeaminase -2.73396
MBLAC2 metallo-beta-lactamase domain containing 2 -2.73396
PCDHB3 protocadherin beta 3 -2.65535
ALCAM activated leukocyte cell adhesion molecule -2.62192
KNSTRN kinetochore-localized astrin/SPAG5 binding protein -2.61954
COQ3 coenzyme Q3 methyltransferase -2.59722
ZNF14 zinc finger protein 14 -2.59065
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.58365
VMAC vimentin-type intermediate filament associated coiled-coil protein -2.55974
NES nestin -2.53852
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -2.52099
RAB11FIP2 RAB11 family interacting protein 2 (class I) -2.47883
TENT4A terminal nucleotidyltransferase 4A -2.46341
TMEM234 transmembrane protein 234 -2.36268
SPAG7 sperm associated antigen 7 -2.3587
PHF7 PHD finger protein 7 -2.31209
IGFLR1 IGF-like family receptor 1 -2.2944
ELMO3 engulfment and cell motility 3 -2.29365
TDRD7 tudor domain containing 7 -2.29365
EFCAB6 EF-hand calcium binding domain 6 -2.27407
OSTN osteocrin -2.26317
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -2.26317
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C -2.26317
LRRC39 leucine rich repeat containing 39 -2.26317
CRIP2 cysteine-rich protein 2 -2.26317
SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 -2.26317
TEPSIN TEPSIN adaptor related protein complex 4 accessory protein -2.23806
ADPRHL1 ADP-ribosylhydrolase like 1 -2.23806
SEC11C SEC11 homolog C (S. cerevisiae) -2.23806
FBP2 fructose-1,6-bisphosphatase 2 -2.23806
SLC35E3 solute carrier family 35, member E3 -2.21821
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.20753
TBX19 T-box 19 -2.20634
ADAP2 ArfGAP with dual PH domains 2 -2.19659
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.19659
ZFYVE26 zinc finger, FYVE domain containing 26 -2.18445
ELOVL5 ELOVL fatty acid elongase 5 -2.17025
RPS27L ribosomal protein S27-like -2.17025
ANKRD44 ankyrin repeat domain 44 -2.13955
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.13881
TMEM37 transmembrane protein 37 -2.11503
VIL1 villin 1 -2.10794
USP25 ubiquitin specific peptidase 25 -2.0935
NUDCD2 NudC domain containing 2 -2.0935
UBXN4 UBX domain protein 4 -2.07806
FRMPD3 FERM and PDZ domain containing 3 -2.0662
IGSF1 immunoglobulin superfamily, member 1 -2.06524
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.06429
GTF2I general transcription factor IIi -2.06365
ZNF883 zinc finger protein 883 -2.06024
COPG1 coatomer protein complex, subunit gamma 1 -2.05144
NR2C2AP nuclear receptor 2C2-associated protein -2.04675
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -2.04227
HSPA4L heat shock 70kDa protein 4-like -2.04227
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -2.02851
SSTR2 somatostatin receptor 2 -2.01906
PBX3 pre-B-cell leukemia homeobox 3 -2.01906
CD4 CD4 molecule -2.01539