TETRODOTOXIN Gene Set

Dataset	DGIdb Drug Targets 2026
Category	physical interactions
Type	drug
Description	A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels. (Chemical Entities of Biological Interest Ontology, CHEBI_9506)
External Link	https://dgidb.org/results?searchType=drug&searchTerms=TETRODOTOXIN
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Genes

10 interacting proteins for the TETRODOTOXIN drug from theDGIdb Drug Targets 2026 dataset.

Symbol	Name	Standardized Value
XK	X-linked Kx blood group	0.147033
SCN3A	sodium channel, voltage gated, type III alpha subunit	0.126892
SCN4A	sodium channel, voltage gated, type IV alpha subunit	0.121883
SCN1A	sodium channel, voltage gated, type I alpha subunit	0.118758
SCN5A	sodium channel, voltage gated, type V alpha subunit	0.0998717
SCN9A	sodium channel, voltage gated, type IX alpha subunit	0.0975063
SCN11A	sodium channel, voltage gated, type XI alpha subunit	0.0802
SCN2A	sodium channel, voltage gated, type II alpha subunit	0.0696474
SCN8A	sodium channel, voltage gated, type VIII alpha subunit	0.0687428
SCN10A	sodium channel, voltage gated, type X alpha subunit	0.058167