TFAP2A Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)|The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 7020)
External Link http://www.ncbi.nlm.nih.gov/gene/7020
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75 interacting proteins for TFAP2A from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APC adenomatous polyposis coli
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
BRCA1 breast cancer 1, early onset
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD59 CD59 molecule, complement regulatory protein
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CLTC clathrin, heavy chain (Hc)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DEK DEK proto-oncogene
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPN1 epsin 1
EPN2 epsin 2
EPPK1 epiplakin 1
EPS15 epidermal growth factor receptor pathway substrate 15
GRB2 growth factor receptor-bound protein 2
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HIP1 huntingtin interacting protein 1
HIST1H3B histone cluster 1, H3b
IQGAP1 IQ motif containing GTPase activating protein 1
KCTD1 potassium channel tetramerization domain containing 1
KCTD15 potassium channel tetramerization domain containing 15
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LDLRAP1 low density lipoprotein receptor adaptor protein 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MPRIP myosin phosphatase Rho interacting protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PLEC plectin
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKD1 protein kinase D1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RACGAP1 Rac GTPase activating protein 1
RB1 retinoblastoma 1
SH3BP4 SH3-domain binding protein 4
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SRA1 steroid receptor RNA activator 1
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO4 small ubiquitin-like modifier 4
SYT1 synaptotagmin I
TNF tumor necrosis factor
TP53 tumor protein p53
UBB ubiquitin B
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YBX1 Y box binding protein 1
YY1 YY1 transcription factor