TFEB Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description transcription factor EB| (NCBI Entrez Gene Database, 7942)
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Genes

315 genes differentially expressed following the TFEB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ATP13A4 ATPase type 13A4 2.49438
AGTRAP angiotensin II receptor-associated protein 2.49438
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 2.49438
LIPN lipase, family member N 2.49438
KNG1 kininogen 1 2.49438
SLC46A2 solute carrier family 46, member 2 2.49438
SPINK6 serine peptidase inhibitor, Kazal type 6 2.49438
PRICKLE4 prickle homolog 4 (Drosophila) 2.49438
PRELP proline/arginine-rich end leucine-rich repeat protein 2.49438
TSGA13 testis specific, 13 2.49438
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 2.49438
HLX H2.0-like homeobox 2.49438
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 2.49438
FPR1 formyl peptide receptor 1 2.49438
GUCA1C guanylate cyclase activator 1C 2.49438
OR6T1 olfactory receptor, family 6, subfamily T, member 1 2.49438
KLHL35 kelch-like family member 35 2.49438
GPR4 G protein-coupled receptor 4 2.49438
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.49438
SRPX2 sushi-repeat containing protein, X-linked 2 2.49438
TMEM212 transmembrane protein 212 2.49438
TNNI1 troponin I type 1 (skeletal, slow) 2.49438
SLC25A45 solute carrier family 25, member 45 2.49438
TNS4 tensin 4 2.49438
LCN12 lipocalin 12 2.49438
RGPD3 RANBP2-like and GRIP domain containing 3 2.49438
TCP11 t-complex 11, testis-specific 2.49438
STOML1 stomatin (EPB72)-like 1 2.49438
MPL MPL proto-oncogene, thrombopoietin receptor 2.49438
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.49438
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 2.49438
THEMIS thymocyte selection associated 2.49438
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.49438
BAAT bile acid CoA:amino acid N-acyltransferase 2.49438
APLN apelin 2.49438
TMEM177 transmembrane protein 177 2.49438
GFAP glial fibrillary acidic protein 2.49438
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 2.49438
MSC musculin 2.49438
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.49438
GYPE glycophorin E (MNS blood group) 2.49438
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.49438
TNIP3 TNFAIP3 interacting protein 3 2.49438
KCNU1 potassium channel, subfamily U, member 1 2.49438
OR2I1 olfactory receptor family 2 subfamily I member 1 (gene/pseudogene) 2.49438
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 2.49438
CCDC9B coiled-coil domain containing 9B 2.49438
VSIR V-set immunoregulatory receptor 2.49438
SQOR sulfide quinone oxidoreductase 2.49438
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.49438
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2.49438
PROP1 PROP paired-like homeobox 1 2.49438
GPX5 glutathione peroxidase 5 2.49438
CD300LF CD300 molecule-like family member f 2.49438
MAB21L4 mab-21 like 4 2.49438
CALHM5 calcium homeostasis modulator family member 5 2.49438
C1ORF232 chromosome 1 open reading frame 230 2.49438
LOC124903372 uncharacterized LOC124903372 2.49438
RHEX regulator of hemoglobinization and erythroid cell expansion 2.49438
H3C3 H3 clustered histone 3 2.49438
CFAP299 cilia and flagella associated protein 299 2.49438
SEPTIN12 septin 12 2.49438
H2AC1 H2A clustered histone 1 2.49438
VXN vexin 2.49438
PLPP4 phospholipid phosphatase 4 2.49438
CXCL13 chemokine (C-X-C motif) ligand 13 2.49438
DNAAF1 dynein, axonemal, assembly factor 1 2.49438
SASH3 SAM and SH3 domain containing 3 2.49438
UBL4B ubiquitin-like 4B 2.49438
PGC progastricsin (pepsinogen C) 2.49438
MTFMT mitochondrial methionyl-tRNA formyltransferase 2.49438
UROC1 urocanate hydratase 1 2.49438
ANXA13 annexin A13 2.49438
DSG1 desmoglein 1 2.49438
VIT vitrin 2.49438
PCDHB10 protocadherin beta 10 2.49438
LRRC70 leucine rich repeat containing 70 2.49438
NPIPB8 nuclear pore complex interacting protein family, member B8 2.49438
FMO2 flavin containing monooxygenase 2 (non-functional) 2.49438
TRIM31 tripartite motif containing 31 2.49438
TREX2 three prime repair exonuclease 2 2.49438
WNT16 wingless-type MMTV integration site family, member 16 2.49438
ZNF441 zinc finger protein 441 2.49438
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.49438
DYNAP dynactin associated protein 2.49438
HNF1A HNF1 homeobox A 2.49438
IL16 interleukin 16 2.49438
PCDHGA10 protocadherin gamma subfamily A, 10 2.49438
LPAR5 lysophosphatidic acid receptor 5 2.49438
SCML4 sex comb on midleg-like 4 (Drosophila) 2.49438
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.49438
KLF2 Kruppel-like factor 2 2.49438
CALHM1 calcium homeostasis modulator 1 2.49438
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.49438
TDRD10 tudor domain containing 10 2.49438
TCP11X1 t-complex 11 family, X-linked 1 2.49438
CLEC4D C-type lectin domain family 4, member D 2.49438
CBX8 chromobox homolog 8 2.49438
DGCR6 DiGeorge syndrome critical region gene 6 2.49438
C11ORF16 chromosome 11 open reading frame 16 2.49438
AGR2 anterior gradient 2 2.49438
NBPF8 neuroblastoma breakpoint family, member 8 2.49438
TBPL2 TATA box binding protein like 2 2.49438
EBF3 early B-cell factor 3 2.49438
RSAD2 radical S-adenosyl methionine domain containing 2 2.49438
APLNR apelin receptor 2.49438
EDN2 endothelin 2 2.49438
CLDN34 claudin 34 2.49438
OR9A4 olfactory receptor, family 9, subfamily A, member 4 2.49438
PCDHGA2 protocadherin gamma subfamily A, 2 2.49438
SHISA8 shisa family member 8 2.49438
ISL2 ISL LIM homeobox 2 2.49438
EFCC1 EF-hand and coiled-coil domain containing 1 2.49438
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.49438
DEFB135 defensin, beta 135 2.49438
C1ORF105 chromosome 1 open reading frame 105 2.49438
HPGDS hematopoietic prostaglandin D synthase 2.49438
CCNA1 cyclin A1 2.49438
ADAM18 ADAM metallopeptidase domain 18 2.49438
ADRA2B adrenoceptor alpha 2B 2.49438
ZNF831 zinc finger protein 831 2.49438
GCHFR GTP cyclohydrolase I feedback regulator 2.49438
SLC38A3 solute carrier family 38, member 3 2.49438
EGR3 early growth response 3 2.49438
ASTL astacin-like metallo-endopeptidase (M12 family) 2.49438
ITGAD integrin, alpha D 2.49438
FSHR follicle stimulating hormone receptor 2.49438
TF transferrin 2.49438
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 2.49438
VAV1 vav 1 guanine nucleotide exchange factor 2.49438
SOSTDC1 sclerostin domain containing 1 2.49438
NCR3 natural cytotoxicity triggering receptor 3 2.49438
PHOX2A paired-like homeobox 2a 2.49438
C5AR2 complement component 5a receptor 2 2.49438
PITX3 paired-like homeodomain 3 2.49438
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.49438
MAGEA12 melanoma antigen family A12 2.49438
BOD1L2 biorientation of chromosomes in cell division 1-like 2 2.49438
XCR1 chemokine (C motif) receptor 1 2.49438
AOC1 amine oxidase, copper containing 1 2.49438
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.49438
FOXG1 forkhead box G1 2.49438
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.49438
KCTD4 potassium channel tetramerization domain containing 4 2.49438
OR4M2 olfactory receptor, family 4, subfamily M, member 2 2.49438
RAB7B RAB7B, member RAS oncogene family 2.49438
CLCNKB chloride channel, voltage-sensitive Kb 2.49438
BIN2 bridging integrator 2 2.49438
FGF16 fibroblast growth factor 16 2.49438
PXT1 peroxisomal, testis specific 1 2.49438
POTEJ POTE ankyrin domain family, member J 2.49438
KIAA1755 KIAA1755 2.49438
CCDC166 coiled-coil domain containing 166 2.49438
APOL3 apolipoprotein L, 3 2.49438
STEAP4 STEAP family member 4 2.49438
PLGLB2 plasminogen-like B2 2.49438
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 2.49438
FNBP1L formin binding protein 1-like 2.49438
BOLA2 bolA family member 2 2.49438
PATE2 prostate and testis expressed 2 2.49438
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.42519
LYPD6 LY6/PLAUR domain containing 6 2.3768
DZANK1 double zinc ribbon and ankyrin repeat domains 1 2.37166
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.36176
GLRA3 glycine receptor, alpha 3 2.36176
SIM1 single-minded family bHLH transcription factor 1 2.36176
GZMM granzyme M (lymphocyte met-ase 1) 2.36176
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.36176
RETREG2 reticulophagy regulator family member 2 2.35171
NKX3-1 NK3 homeobox 1 2.35171
ZNF750 zinc finger protein 750 2.35171
SLCO5A1 solute carrier organic anion transporter family, member 5A1 2.33728
PCDHA5 protocadherin alpha 5 2.33041
RTL5 retrotransposon Gag like 5 2.31185
KMT2E lysine (K)-specific methyltransferase 2E 2.28588
PTCHD1 patched domain containing 1 2.2827
PRKN parkin RBR E3 ubiquitin protein ligase 2.28112
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.27387
SLC30A6 solute carrier family 30 (zinc transporter), member 6 2.27387
MRPL32 mitochondrial ribosomal protein L32 2.26957
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.2668
ZNF395 zinc finger protein 395 2.25257
PDZK1 PDZ domain containing 1 2.20928
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component 2.19202
TMEM38A transmembrane protein 38A 2.19202
GK5 glycerol kinase 5 (putative) 2.19179
LIG4 ligase IV, DNA, ATP-dependent 2.17443
CSNK2A2 casein kinase 2, alpha prime polypeptide 2.17406
ZNF609 zinc finger protein 609 2.17108
RHOH ras homolog family member H 2.16462
FOXP4 forkhead box P4 2.11887
RHOA ras homolog family member A 2.09355
TXNDC9 thioredoxin domain containing 9 2.09355
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.0858
C2ORF92 chromosome 2 open reading frame 92 2.08441
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.08441
GPAT4 glycerol-3-phosphate acyltransferase 4 2.06562
RNMT RNA (guanine-7-) methyltransferase 2.05635
MRFAP1 Morf4 family associated protein 1 2.04881
CKAP5 cytoskeleton associated protein 5 2.04682
GPS2 G protein pathway suppressor 2 2.03565
TMEM44 transmembrane protein 44 2.02764
TMEM143 transmembrane protein 143 2.02764
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.02614
MRPS33 mitochondrial ribosomal protein S33 2.02614
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 2.02204
LAG3 lymphocyte-activation gene 3 2.00767
SALL1 spalt-like transcription factor 1 2.00055

decreased expression

Symbol Name Standardized Value
HEATR9 HEAT repeat containing 9 -2.49438
ACTL8 actin-like 8 -2.49438
RNF4 ring finger protein 4 -2.49438
BBS5 Bardet-Biedl syndrome 5 -2.49438
CPLX1 complexin 1 -2.49438
TVP23A trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) -2.49438
SUMF1 sulfatase modifying factor 1 -2.49438
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -2.49438
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.49438
LHX6 LIM homeobox 6 -2.49438
S1PR1 sphingosine-1-phosphate receptor 1 -2.49438
NPR3 natriuretic peptide receptor 3 -2.49438
CCDC92 coiled-coil domain containing 92 -2.49438
TLR3 toll-like receptor 3 -2.49438
C2CD2L C2CD2-like -2.49438
PDE1B phosphodiesterase 1B, calmodulin-dependent -2.49438
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.49438
GTPBP8 GTP-binding protein 8 (putative) -2.49438
PRSS36 protease, serine, 36 -2.49438
TMEM176B transmembrane protein 176B -2.49438
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -2.49438
ZBTB42 zinc finger and BTB domain containing 42 -2.49438
SH2D7 SH2 domain containing 7 -2.49438
PAX6 paired box 6 -2.49438
LRG1 leucine-rich alpha-2-glycoprotein 1 -2.49438
SFXN3 sideroflexin 3 -2.49438
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 -2.49438
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -2.49438
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -2.49438
LURAP1L leucine rich adaptor protein 1-like -2.49438
PNKD paroxysmal nonkinesigenic dyskinesia -2.49438
SHISA7 shisa family member 7 -2.49438
KCNIP3 Kv channel interacting protein 3, calsenilin -2.49438
COL20A1 collagen, type XX, alpha 1 -2.49438
PPP1R3C protein phosphatase 1, regulatory subunit 3C -2.49438
CHP2 calcineurin-like EF-hand protein 2 -2.49438
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.49438
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -2.49438
MMP24OS MMP24 opposite strand -2.49438
WFDC8 WAP four-disulfide core domain 8 -2.49438
STRIT1 small transmembrane regulator of ion transport 1 -2.49438
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa -2.49438
C2CD4B C2 calcium-dependent domain containing 4B -2.49438
CNTFR ciliary neurotrophic factor receptor -2.49438
PCDH12 protocadherin 12 -2.49438
CCDC73 coiled-coil domain containing 73 -2.49438
CRYBA1 crystallin, beta A1 -2.49438
CNGB3 cyclic nucleotide gated channel beta 3 -2.49438
LOC107986837 uncharacterized LOC107986837 -2.49438
SPIRE1 spire-type actin nucleation factor 1 -2.49438
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -2.49438
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.49438
ZNF112 zinc finger protein 112 -2.49438
DENND2D DENN/MADD domain containing 2D -2.49438
GMDS GDP-mannose 4,6-dehydratase -2.49438
SACK1F scaffolding CK1 anchoring protein F -2.49438
FAM181B family with sequence similarity 181, member B -2.49438
PCSK1 proprotein convertase subtilisin/kexin type 1 -2.49438
TUBGCP6 tubulin, gamma complex associated protein 6 -2.49438
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.49438
CES4A carboxylesterase 4A -2.49438
TDRD12 tudor domain containing 12 -2.49438
ZNRD2 zinc ribbon domain containing 2 -2.37412
SPATA20 spermatogenesis associated 20 -2.36075
RGPD1 RANBP2-like and GRIP domain containing 1 -2.36019
NPIPB12 nuclear pore complex interacting protein family member B12 -2.36019
UBTD1 ubiquitin domain containing 1 -2.35171
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.34661
ETNPPL ethanolamine-phosphate phospho-lyase -2.33041
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 -2.33041
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.27387
ZFAND2A zinc finger, AN1-type domain 2A -2.26877
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -2.26877
XKR6 XK, Kell blood group complex subunit-related family, member 6 -2.2668
ZSCAN26 zinc finger and SCAN domain containing 26 -2.25151
IGF2R insulin-like growth factor 2 receptor -2.22413
STX8 syntaxin 8 -2.21779
SNRK SNF related kinase -2.20007
DENND4B DENN/MADD domain containing 4B -2.19272
HNMT histamine N-methyltransferase -2.19272
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -2.19272
SMTN smoothelin -2.19202
HSPH1 heat shock 105kDa/110kDa protein 1 -2.19202
OTUD7A OTU deubiquitinase 7A -2.19202
MIB1 mindbomb E3 ubiquitin protein ligase 1 -2.19179
KMT2D lysine (K)-specific methyltransferase 2D -2.19142
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.19142
PRMT9 protein arginine methyltransferase 9 -2.17114
CCDC136 coiled-coil domain containing 136 -2.16856
SREBF2 sterol regulatory element binding transcription factor 2 -2.16462
NECAP1 NECAP endocytosis associated 1 -2.16462
H2BC8 H2B clustered histone 8 -2.16323
PRCP prolylcarboxypeptidase (angiotensinase C) -2.16066
TRAP1 TNF receptor-associated protein 1 -2.13973
TMEM70 transmembrane protein 70 -2.13206
MPI mannose phosphate isomerase -2.12532
HPF1 histone PARylation factor 1 -2.11887
SMCO2 single-pass membrane protein with coiled-coil domains 2 -2.1064
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.1064
NCOA7 nuclear receptor coactivator 7 -2.09181
EGFL8 EGF-like-domain, multiple 8 -2.0898
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.07525
RIOK3 RIO kinase 3 -2.07037
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 -2.05452
SFRP1 secreted frizzled-related protein 1 -2.04881
TRIM56 tripartite motif containing 56 -2.04519
APCDD1L adenomatosis polyposis coli down-regulated 1-like -2.01444