TFRC Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description transferrin receptor| (NCBI Entrez Gene Database, 7037)
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Genes

316 genes differentially expressed following the TFRC gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GNG8 guanine nucleotide binding protein (G protein), gamma 8 3.28262
GH2 growth hormone 2 3.28262
DNAI7 dynein axonemal intermediate chain 7 3.28262
NECTIN4 nectin cell adhesion molecule 4 3.28262
PTGER4 prostaglandin E receptor 4 (subtype EP4) 3.28262
CD300LF CD300 molecule-like family member f 3.28262
RHCG Rh family, C glycoprotein 3.28262
POPDC2 popeye domain containing 2 3.28262
NFAM1 NFAT activating protein with ITAM motif 1 3.28262
PCDHB10 protocadherin beta 10 3.28262
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 3.28262
BSX brain-specific homeobox 3.28262
ARHGAP20 Rho GTPase activating protein 20 3.28262
NOX3 NADPH oxidase 3 3.28262
RAD9B RAD9 homolog B (S. pombe) 3.28262
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.28262
KIAA1755 KIAA1755 3.28262
CFAP61 cilia and flagella associated protein 61 3.28262
STMN4 stathmin-like 4 3.28262
SPTBN5 spectrin, beta, non-erythrocytic 5 3.28262
NDRG1 N-myc downstream regulated 1 3.24084
HORMAD1 HORMA domain containing 1 3.24084
IGFL4 IGF-like family member 4 3.24084
GLYAT glycine-N-acyltransferase 3.24084
PRSS41 protease, serine, 41 3.24084
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 3.24084
IL36G interleukin 36, gamma 3.24084
VCX3A variable charge, X-linked 3A 3.24084
ARID3C AT rich interactive domain 3C (BRIGHT-like) 3.24084
RAET1E retinoic acid early transcript 1E 3.24084
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.24084
CFHR4 complement factor H-related 4 3.24084
HNF4A hepatocyte nuclear factor 4, alpha 3.24084
PNMA5 paraneoplastic Ma antigen family member 5 3.24084
MYL7 myosin, light chain 7, regulatory 3.24084
NPIPA3 nuclear pore complex interacting protein family, member A3 3.24084
LGI1 leucine-rich, glioma inactivated 1 3.24084
C8ORF74 chromosome 8 open reading frame 74 3.24084
DPPA3 developmental pluripotency associated 3 3.24084
MMP20 matrix metallopeptidase 20 3.24084
F2 coagulation factor II (thrombin) 3.24084
CELA1 chymotrypsin-like elastase family, member 1 3.24084
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 3.24084
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 3.24084
NEU4 sialidase 4 3.24084
MSC musculin 3.24084
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 3.24084
MTTP microsomal triglyceride transfer protein 3.24084
FOXR1 forkhead box R1 3.24084
LRRC56 leucine rich repeat containing 56 3.24084
SKOR2 SKI family transcriptional corepressor 2 3.24084
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 3.24084
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 3.24084
ULBP1 UL16 binding protein 1 3.24084
TMEM40 transmembrane protein 40 3.24084
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 3.24084
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 3.24084
PDC phosducin 3.24084
DEFB131B defensin beta 131B 3.24084
ROPN1L rhophilin associated tail protein 1-like 3.24084
GOLGA6L7 golgin A6 family like 7 3.24084
PHF24 PHD finger protein 24 3.24084
RTL5 retrotransposon Gag like 5 3.24084
SPATA46 spermatogenesis associated 46 3.24084
CHCT1 CHD1 helical C-terminal domain containing 1 3.24084
H2BW1 H2B.W histone 1 3.24084
GSTT4 glutathione S-transferase theta 4 3.24084
MUCL3 mucin like 3 3.24084
NOTCH2NLB notch 2 N-terminal like B 3.24084
TEKTL1 tektin like 1 3.24084
CATSPERH catsper channel auxiliary subunit eta 3.24084
DOK7 docking protein 7 3.24084
TSPAN1 tetraspanin 1 3.24084
PRDM7 PR domain containing 7 3.24084
SCRT2 scratch family zinc finger 2 3.24084
DMBX1 diencephalon/mesencephalon homeobox 1 3.24084
IL6 interleukin 6 3.24084
SLC45A2 solute carrier family 45, member 2 3.24084
GLP2R glucagon-like peptide 2 receptor 3.24084
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.24084
ARMS2 age-related maculopathy susceptibility 2 3.24084
EXOC3L1 exocyst complex component 3-like 1 3.24084
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 3.24084
SASH3 SAM and SH3 domain containing 3 3.24084
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.24084
C7 complement component 7 3.24084
ADIG adipogenin 3.24084
PNPLA1 patatin-like phospholipase domain containing 1 3.24084
GDF6 growth differentiation factor 6 3.24084
PRG4 proteoglycan 4 3.24084
LTB lymphotoxin beta (TNF superfamily, member 3) 3.24084
COXFA4L3 cytochrome c oxidase associated subunit FA4L3 3.24084
MEPE matrix extracellular phosphoglycoprotein 3.24084
DQX1 DEAQ box RNA-dependent ATPase 1 3.24084
EFCAB3 EF-hand calcium binding domain 3 3.24084
LRTM2 leucine-rich repeats and transmembrane domains 2 3.24084
SOWAHA sosondowah ankyrin repeat domain family member A 3.24084
BRDT bromodomain, testis-specific 3.24084
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 3.24084
GFI1B growth factor independent 1B transcription repressor 3.24084
STAB1 stabilin 1 3.24084
PHOSPHO1 phosphatase, orphan 1 3.24084
ZMYND10 zinc finger, MYND-type containing 10 3.24084
C9ORF50 chromosome 9 open reading frame 50 3.24084
C9ORF57 chromosome 9 open reading frame 57 3.24084
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 3.24084
DEFB134 defensin, beta 134 3.24084
AQP7 aquaporin 7 3.24084
GLT6D1 glycosyltransferase 6 domain containing 1 3.24084
AQP6 aquaporin 6, kidney specific 3.24084
CPSF4L cleavage and polyadenylation specific factor 4-like 3.24084
SCML4 sex comb on midleg-like 4 (Drosophila) 3.24084
CDH22 cadherin 22, type 2 3.24084
CISH cytokine inducible SH2-containing protein 3.24084
TH tyrosine hydroxylase 3.24084
SPEF1 sperm flagellar 1 3.24084
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.24084
KLK3 kallikrein-related peptidase 3 3.24084
SHARPIN SHANK-associated RH domain interactor 3.24084
HRCT1 histidine rich carboxyl terminus 1 3.24084
CHI3L2 chitinase 3-like 2 3.24084
MB myoglobin 3.24084
MUC13 mucin 13, cell surface associated 3.24084
COX7B2 cytochrome c oxidase subunit VIIb2 3.24084
SPRR2F small proline-rich protein 2F 3.24084
FOXE3 forkhead box E3 3.24084
C22ORF42 chromosome 22 open reading frame 42 3.24084
ADAM7 ADAM metallopeptidase domain 7 3.24084
OR11G2 olfactory receptor, family 11, subfamily G, member 2 3.24084
MSLN mesothelin 3.24084
BIN2 bridging integrator 2 3.24084
FGF9 fibroblast growth factor 9 3.24084
PTPN20 protein tyrosine phosphatase, non-receptor type 20 3.24084
NLRP6 NLR family, pyrin domain containing 6 3.24084
IFNK interferon, kappa 3.24084
LPA lipoprotein, Lp(a) 3.24084
BPIFC BPI fold containing family C 3.24084
TGM5 transglutaminase 5 3.24084
DUOXA1 dual oxidase maturation factor 1 3.24084
GHRH growth hormone releasing hormone 3.24084
PRR29 proline rich 29 3.24084
SPAG6 sperm associated antigen 6 3.24084
AQP1 aquaporin 1 (Colton blood group) 3.24084
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.24084
PPY pancreatic polypeptide 3.24084
ZPLD1 zona pellucida-like domain containing 1 3.24084
CAMTA2 calmodulin binding transcription activator 2 3.10333
DLG3 discs, large homolog 3 (Drosophila) 2.85417
GPC2 glypican 2 2.85417
VIPR1 vasoactive intestinal peptide receptor 1 2.85191
HARS1 histidyl-tRNA synthetase 1 2.68742
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 2.62795
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 2.59418
PLD2 phospholipase D2 2.59418
GPRASP2 G protein-coupled receptor associated sorting protein 2 2.575
MICALL1 MICAL-like 1 2.53814
IL15 interleukin 15 2.4316
LRRK1 leucine-rich repeat kinase 1 2.3971
TRHR thyrotropin-releasing hormone receptor 2.3971
IDNK idnK, gluconokinase homolog (E. coli) 2.36963
LRRC55 leucine rich repeat containing 55 2.36128
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.36128
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 2.34733
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 2.33248
PARG poly (ADP-ribose) glycohydrolase 2.31861
CDIN1 CDAN1 interacting nuclease 1 2.31333
CCDC138 coiled-coil domain containing 138 2.27124
SAPCD1 suppressor APC domain containing 1 2.26592
MROH6 maestro heat-like repeat family member 6 2.26592
NELL1 NEL-like 1 (chicken) 2.26592
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.26592
ZNF506 zinc finger protein 506 2.23349
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.23349
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 2.22359
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.20427
FLCN folliculin 2.19976
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.19608
SATL1 spermidine/spermine N1-acetyl transferase-like 1 2.19608
CLTB clathrin, light chain B 2.17495
PDCD2 programmed cell death 2 2.17456
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.17456
BIN1 bridging integrator 1 2.13341
SDC2 syndecan 2 2.12754
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.12754
OLFM3 olfactomedin 3 2.12122
AKAP17A A kinase (PRKA) anchor protein 17A 2.12122
WRNIP1 Werner helicase interacting protein 1 2.11486
MED22 mediator complex subunit 22 2.09971
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.09504
MARVELD2 MARVEL domain containing 2 2.09187
WBP1L WW domain binding protein 1-like 2.06893
ZNF629 zinc finger protein 629 2.06308
NCKAP5L NCK-associated protein 5-like 2.05349
TPD52 tumor protein D52 2.05274
ATE1 arginyltransferase 1 2.05057
CGAS cyclic GMP-AMP synthase 2.0424
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.0424
COBL cordon-bleu WH2 repeat protein 2.0294
CRACDL CRACD like 2.00687
TEX10 testis expressed 10 2.00608
CCDC184 coiled-coil domain containing 184 2.00608
ADD2 adducin 2 (beta) 2.00608

decreased expression

Symbol Name Standardized Value
C7orf78 chromosome 7 open reading frame 78 -3.28262
ESR1 estrogen receptor 1 -3.28262
PELI3 pellino E3 ubiquitin protein ligase family member 3 -3.28262
CNGA4 cyclic nucleotide gated channel alpha 4 -3.28262
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -3.28262
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -3.28262
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -3.28262
H4C13 H4 clustered histone 13 -3.28262
FAM78A family with sequence similarity 78, member A -3.28262
PSRC1 proline/serine-rich coiled-coil 1 -3.24084
PSCA prostate stem cell antigen -3.19836
KYNU kynureninase -3.19836
FRG2C FSHD region gene 2 family, member C -3.19836
CSAG3 CSAG family, member 3 -3.19836
MAGEB17 melanoma antigen family B17 -3.19836
FZD1 frizzled class receptor 1 -3.19836
LDHC lactate dehydrogenase C -3.19836
ADIRF adipogenesis regulatory factor -3.19836
ASIC4 acid sensing (proton gated) ion channel family member 4 -3.19836
NDP Norrie disease (pseudoglioma) -3.19836
MMP3 matrix metallopeptidase 3 -3.19836
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -3.19836
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -3.19836
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -3.19836
DUSP8 dual specificity phosphatase 8 -3.19836
PTH2 parathyroid hormone 2 -3.19836
HAS1 hyaluronan synthase 1 -3.19836
ORM2 orosomucoid 2 -3.19836
STYXL2 serine/threonine/tyrosine interacting like 2 -3.19836
NOTCH4 notch 4 -3.19836
SCARA5 scavenger receptor class A, member 5 -3.19836
CCDC177 coiled-coil domain containing 177 -3.19836
IQCN IQ motif containing N -3.19836
OLIG1 oligodendrocyte transcription factor 1 -3.19836
DMRT1 doublesex and mab-3 related transcription factor 1 -3.19836
PTGER3 prostaglandin E receptor 3 (subtype EP3) -3.19836
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -3.19836
TRIM74 tripartite motif containing 74 -3.19836
CCER2 coiled-coil glutamate-rich protein 2 -3.19836
IL1A interleukin 1, alpha -3.19836
HHEX hematopoietically expressed homeobox -3.19836
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -3.19836
EPHA10 EPH receptor A10 -3.19836
RANBP3L RAN binding protein 3-like -3.19836
KCTD11 potassium channel tetramerization domain containing 11 -3.15402
SPARCL1 SPARC-like 1 (hevin) -3.11077
YBX1 Y box binding protein 1 -3.09761
ZNF135 zinc finger protein 135 -3.09232
SRRM5 serine/arginine repetitive matrix 5 -3.08042
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -3.00564
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.76391
MCF2 MCF.2 cell line derived transforming sequence -2.66256
BAIAP2L2 BAI1-associated protein 2-like 2 -2.66256
SYNGR3 synaptogyrin 3 -2.6326
FAM133B family with sequence similarity 133, member B -2.6145
BCL6B B-cell CLL/lymphoma 6, member B -2.61239
ACKR4 atypical chemokine receptor 4 -2.61239
HRC histidine rich calcium binding protein -2.53507
SGSM2 small G protein signaling modulator 2 -2.53435
ZNF165 zinc finger protein 165 -2.5326
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 -2.47462
ZNF709 zinc finger protein 709 -2.44958
KLC3 kinesin light chain 3 -2.44369
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.44369
PKLR pyruvate kinase, liver and RBC -2.44369
FAM76A family with sequence similarity 76, member A -2.44047
VPS9D1 VPS9 domain containing 1 -2.44047
RHOBTB1 Rho-related BTB domain containing 1 -2.36963
CCDC194 coiled-coil domain containing 194 -2.36963
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) -2.3499
FKBP5 FK506 binding protein 5 -2.34843
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -2.29142
RHOU ras homolog family member U -2.28564
CLDN12 claudin 12 -2.27366
SYT3 synaptotagmin III -2.27366
NBPF15 neuroblastoma breakpoint family, member 15 -2.26592
NBEAL2 neurobeachin-like 2 -2.22359
B3GAT2 beta-1,3-glucuronyltransferase 2 -2.21793
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -2.20427
COQ6 coenzyme Q6 monooxygenase -2.19784
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.19608
H4C1 H4 clustered histone 1 -2.19608
AURKB aurora kinase B -2.18278
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -2.17739
IQGAP3 IQ motif containing GTPase activating protein 3 -2.17189
RPL10 ribosomal protein L10 -2.164
SGO1 shugoshin 1 -2.14579
RGN regucalcin -2.13088
ATF3 activating transcription factor 3 -2.12122
TPD52L1 tumor protein D52-like 1 -2.10486
SRSF1 serine/arginine-rich splicing factor 1 -2.10034
SLC35A4 solute carrier family 35, member A4 -2.08894
LRRC26 leucine rich repeat containing 26 -2.08538
DCLK2 doublecortin-like kinase 2 -2.08538
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.08538
ELF4 E74-like factor 4 (ets domain transcription factor) -2.08538
SYBU syntabulin (syntaxin-interacting) -2.08538
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 -2.08538
FLNC filamin C, gamma -2.08538
OVOL1 ovo-like zinc finger 1 -2.08538
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -2.07878
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -2.06893
CHLSN cholesin -2.06308
KMT2A lysine (K)-specific methyltransferase 2A -2.06308
CDC14B cell division cycle 14B -2.05349
TMEM134 transmembrane protein 134 -2.05274
ALPL alkaline phosphatase, liver/bone/kidney -2.05057
NIBAN1 niban apoptosis regulator 1 -2.0424
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -2.038
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.03398
STARD5 StAR-related lipid transfer (START) domain containing 5 -2.03084
YY1AP1 YY1 associated protein 1 -2.01893
KIF23 kinesin family member 23 -2.01719
POGLUT2 protein O-glucosyltransferase 2 -2.01719