TGF-beta receptor signaling activates SMADs Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-2173789
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Genes

47 proteins participating in the TGF-beta receptor signaling activates SMADs pathway from the Reactome Pathways 2024 dataset.

Symbol Name
BAMBI BMP and activin membrane-bound inhibitor
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
FBN1 fibrillin 1
FKBP1A FK506 binding protein 1A, 12kDa
FURIN furin (paired basic amino acid cleaving enzyme)
ITGA8 integrin, alpha 8
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
ITGB8 integrin, beta 8
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
MTMR4 myotubularin related protein 4
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
PMEPA1 prostate transmembrane protein, androgen induced 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RPS27A ribosomal protein S27a
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
STRAP serine/threonine kinase receptor associated protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2M ubiquitin-conjugating enzyme E2M
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP25 ubiquitin specific peptidase 25
XPO1 exportin 1
ZFYVE9 zinc finger, FYVE domain containing 9