TGF-beta signaling pathway Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
External Link https://www.kegg.jp/entry/hsa04350
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Genes

109 proteins participating in the TGF-beta signaling pathway pathway from the KEGG Pathways 2026 dataset.

Symbol Name
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
BAMBI BMP and activin membrane-bound inhibitor
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHRD chordin
CREBBP CREB binding protein
CUL1 cullin 1
DAND5 DAN domain family member 5, BMP antagonist
DCN decorin
E2F4 E2F transcription factor 4, p107/p130-binding
E2F5 E2F transcription factor 5, p130-binding
EMP3 epithelial membrane protein 3
EP300 E1A binding protein p300
FBN1 fibrillin 1
FMOD fibromodulin
FST follistatin
GDF5 growth differentiation factor 5
GDF6 growth differentiation factor 6
GDF7 growth differentiation factor 7
GREM1 gremlin 1, DAN family BMP antagonist
GREM2 gremlin 2, DAN family BMP antagonist
HAMP hepcidin antimicrobial peptide
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HFE hemochromatosis
HJV hemojuvelin BMP co-receptor
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IGSF1 immunoglobulin superfamily, member 1
INHBA inhibin, beta A
INHBB inhibin, beta B
INHBC inhibin, beta C
INHBE inhibin, beta E
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LEMD3 LEM domain containing 3
LINC02762 long intergenic non-protein coding RNA 2762
LRRC32 leucine rich repeat containing 32
LTBP1 latent transforming growth factor beta binding protein 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NEO1 neogenin 1
NODAL nodal growth differentiation factor
NOG noggin
NRROS negative regulator of reactive oxygen species
PITX2 paired-like homeodomain 2
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
RBL1 retinoblastoma-like 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RGMA repulsive guidance molecule family member a
RGMB repulsive guidance molecule family member b
RHOA ras homolog family member A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SIN3A SIN3 transcription regulator family member A
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SKP1 S-phase kinase-associated protein 1
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMAD9 SMAD family member 9
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
TF transferrin
TFDP1 transcription factor Dp-1
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGIF1 TGFB-induced factor homeobox 1
TGIF2 TGFB-induced factor homeobox 2
THBS1 thrombospondin 1
THSD4 thrombospondin, type I, domain containing 4
TMEM53 transmembrane protein 53
TNF tumor necrosis factor
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE9 zinc finger, FYVE domain containing 9