TGFBR1 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description transforming growth factor, beta receptor 1|The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 7046)
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100 substrates of the kinase TGFBR1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
EIF5B eukaryotic translation initiation factor 5B
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
CLNS1A chloride channel, nucleotide-sensitive, 1A
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
NUCLEOLIN nucleolin multifunctional protein
MIER1 mesoderm induction early response 1, transcriptional regulator
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
ERBB2IP erbb2 interacting protein
NPHP1 nephronophthisis 1 (juvenile)
FAM21A family with sequence similarity 21, member A
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
NEK1 NIMA-related kinase 1
NPM3 nucleophosmin/nucleoplasmin 3
TUBB3 tubulin, beta 3 class III
TUBB1 tubulin, beta 1 class VI
HP1BP3 heterochromatin protein 1, binding protein 3
CHGB chromogranin B
MICALL2 MICAL-like 2
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
FTO fat mass and obesity associated
EHD2 EH-domain containing 2
PRMT6 protein arginine methyltransferase 6
CTR9 CTR9, Paf1/RNA polymerase II complex component
CLGN calmegin
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
TMEM110 transmembrane protein 110
HNF1B HNF1 homeobox B
STRN4 striatin, calmodulin binding protein 4
PRPF38A pre-mRNA processing factor 38A
KAT6A K(lysine) acetyltransferase 6A
BZW1 basic leucine zipper and W2 domains 1
BZW2 basic leucine zipper and W2 domains 2
ZCRB1 zinc finger CCHC-type and RNA binding motif 1
FAM13A family with sequence similarity 13, member A
HTATSF1 HIV-1 Tat specific factor 1
BRMS1 breast cancer metastasis suppressor 1
WBP11 WW domain binding protein 11
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
POLR2M polymerase (RNA) II (DNA directed) polypeptide M
ANKHD1 ankyrin repeat and KH domain containing 1
CCDC97 coiled-coil domain containing 97
ARID4A AT rich interactive domain 4A (RBP1-like)
ZNF777 zinc finger protein 777
SF3A1 splicing factor 3a, subunit 1, 120kDa
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
MRVI1 murine retrovirus integration site 1 homolog
TRIP12 thyroid hormone receptor interactor 12
NOM1 nucleolar protein with MIF4G domain 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
GCOM1 GRINL1A complex locus 1
MYBBP1A MYB binding protein (P160) 1a
HDAC6 histone deacetylase 6
XPC xeroderma pigmentosum, complementation group C
NOP2 NOP2 nucleolar protein
NACA2 nascent polypeptide-associated complex alpha subunit 2
COIL coilin
NEK3 NIMA-related kinase 3
DEK DEK proto-oncogene
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
KRI1 KRI1 homolog (S. cerevisiae)
CADPS2 Ca++-dependent secretion activator 2
PCNP PEST proteolytic signal containing nuclear protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
SKA3 spindle and kinetochore associated complex subunit 3
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NACA nascent polypeptide-associated complex alpha subunit
ANTXR1 anthrax toxin receptor 1
ZEB1 zinc finger E-box binding homeobox 1
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough
TYSND1 trypsin domain containing 1
LIG1 ligase I, DNA, ATP-dependent
PRPF3 pre-mRNA processing factor 3
NES nestin
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
C6ORF203 chromosome 6 open reading frame 203
TJP1 tight junction protein 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
SENP6 SUMO1/sentrin specific peptidase 6
PELP1 proline, glutamate and leucine rich protein 1
U2SURP U2 snRNP-associated SURP domain containing
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
TFIP11 tuftelin interacting protein 11
QSER1 glutamine and serine rich 1
PURB purine-rich element binding protein B
LAT2 linker for activation of T cells family, member 2
GPATCH11 G patch domain containing 11
MDN1 MDN1, midasin homolog (yeast)
HIRIP3 HIRA interacting protein 3
NEMF nuclear export mediator factor
EIF1AD eukaryotic translation initiation factor 1A domain containing
FBLN2 fibulin 2