TGFBR1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description transforming growth factor, beta receptor 1|The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 7046)
External Link http://www.ncbi.nlm.nih.gov/gene/7046
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Genes

6 substrates of the kinase TGFBR1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
ENG endoglin
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
SMAD2 SMAD family member 2
TGFBR3 transforming growth factor, beta receptor III
TP63 tumor protein p63