TGFBR2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description transforming growth factor, beta receptor II (70/80kDa)|This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7048)
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Genes

517 genes differentially expressed following the TGFBR2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
COL19A1 collagen, type XIX, alpha 1 3.91576
PDIA2 protein disulfide isomerase family A, member 2 3.91576
TMEM244 transmembrane protein 244 3.91576
PCDHGB3 protocadherin gamma subfamily B, 3 3.91576
CLEC19A C-type lectin domain family 19, member A 3.91576
OSR2 odd-skipped related transciption factor 2 3.91576
GJB5 gap junction protein, beta 5, 31.1kDa 3.91576
CSTL1 cystatin-like 1 3.91576
OR2J3 olfactory receptor, family 2, subfamily J, member 3 3.91576
C6ORF58 chromosome 6 open reading frame 58 3.91576
OLIG3 oligodendrocyte transcription factor 3 3.91576
SSMEM1 serine-rich single-pass membrane protein 1 3.91576
MEI1 meiosis inhibitor 1 3.91576
FGL2 fibrinogen-like 2 3.91576
BTC betacellulin 3.91576
CAMP cathelicidin antimicrobial peptide 3.91576
CFHR4 complement factor H-related 4 3.91576
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 3.91576
ALB albumin 3.91576
NPAP1 nuclear pore associated protein 1 3.91576
FGD2 FYVE, RhoGEF and PH domain containing 2 3.91576
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.91576
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.91576
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 3.91576
ENTHD1 ENTH domain containing 1 3.91576
HEATR9 HEAT repeat containing 9 3.91576
SPINK4 serine peptidase inhibitor, Kazal type 4 3.91576
TMEM176B transmembrane protein 176B 3.91576
FOLR3 folate receptor 3 (gamma) 3.91576
GIMAP8 GTPase, IMAP family member 8 3.91576
SLC23A3 solute carrier family 23, member 3 3.91576
GALP galanin-like peptide 3.91576
CD33 CD33 molecule 3.91576
ABRA actin binding Rho activating protein 3.91576
CD226 CD226 molecule 3.91576
ICAM5 intercellular adhesion molecule 5, telencephalin 3.91576
POPDC2 popeye domain containing 2 3.91576
KCNK18 potassium channel, two pore domain subfamily K, member 18 3.91576
TMPRSS15 transmembrane protease, serine 15 3.91576
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.91576
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 3.91576
CLCNKB chloride channel, voltage-sensitive Kb 3.91576
IL10RA interleukin 10 receptor, alpha 3.91576
DSPP dentin sialophosphoprotein 3.91576
EBI3 Epstein-Barr virus induced 3 3.91576
BTBD19 BTB (POZ) domain containing 19 3.91576
RFPL3 ret finger protein-like 3 3.91576
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.91576
C3ORF22 chromosome 3 open reading frame 22 3.91576
PCDH8 protocadherin 8 3.91576
EDDM3A epididymal protein 3A 3.91576
PSCA prostate stem cell antigen 3.91576
LACTBL1 lactamase, beta-like 1 3.91576
SOWAHB sosondowah ankyrin repeat domain family member B 3.91576
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.91576
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 3.91576
KLLN killin, p53-regulated DNA replication inhibitor 3.91576
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 3.91576
BIN2 bridging integrator 2 3.91576
SPMIP9 sperm microtubule inner protein 9 3.91576
LORICRIN loricrin cornified envelope precursor protein 3.91576
SLURP2 secreted LY6/PLAUR domain containing 2 3.91576
FYB1 FYN binding protein 1 3.91576
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 3.91576
CES4A carboxylesterase 4A 3.91576
ZNF726 zinc finger protein 726 3.91576
PNLIPRP2 pancreatic lipase-related protein 2 3.91576
DUSP8 dual specificity phosphatase 8 3.91576
DNAAF1 dynein, axonemal, assembly factor 1 3.91576
SRGN serglycin 3.91576
C1QTNF9B C1q and tumor necrosis factor related protein 9B 3.91576
ANO3 anoctamin 3 3.91576
KASH5 KASH domain containing 5 3.91576
CIROP ciliated left-right organizer metallopeptidase 3.91576
SOFU1 sperm-oocyte fusion factor 1 3.91576
SMIM32 small integral membrane protein 32 3.91576
WASL-DT WASL divergent transcript 3.91576
NOTCH2NLB notch 2 N-terminal like B 3.91576
CIMAP1B ciliary microtubule associated protein 1B 3.91576
LY6L lymphocyte antigen 6 family member L 3.91576
GLYATL1B glycine-N-acyltransferase like 1B 3.91576
IHO1 interactor of HORMAD1 1 3.91576
CFAP299 cilia and flagella associated protein 299 3.91576
H2BW2 H2B.W histone 2 3.91576
CFAP206 cilia and flagella associated protein 206 3.91576
GARIN1A golgi associated RAB2 interactor 1A 3.91576
SPDYE9 speedy/RINGO cell cycle regulator family member E9 3.91576
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 3.91576
TMPRSS3 transmembrane protease, serine 3 3.91576
PROX2 prospero homeobox 2 3.91576
C1QTNF8 C1q and tumor necrosis factor related protein 8 3.91576
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.91576
AWAT2 acyl-CoA wax alcohol acyltransferase 2 3.91576
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.91576
LDHAL6B lactate dehydrogenase A-like 6B 3.91576
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.91576
CLEC3A C-type lectin domain family 3, member A 3.91576
CHRD chordin 3.91576
MAGEB3 melanoma antigen family B3 3.91576
KLHL33 kelch-like family member 33 3.91576
CCIN calicin 3.91576
NRN1 neuritin 1 3.91576
PRR19 proline rich 19 3.91576
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 3.91576
NPFF neuropeptide FF-amide peptide precursor 3.91576
OR1C1 olfactory receptor, family 1, subfamily C, member 1 3.91576
GATA4 GATA binding protein 4 3.91576
CSAG3 CSAG family, member 3 3.91576
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.91576
DLK1 delta-like 1 homolog (Drosophila) 3.91576
TMEM119 transmembrane protein 119 3.91576
COX8C cytochrome c oxidase subunit VIIIC 3.91576
NPIPB8 nuclear pore complex interacting protein family, member B8 3.91576
GPR83 G protein-coupled receptor 83 3.91576
PNPLA1 patatin-like phospholipase domain containing 1 3.91576
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 3.91576
SBSN suprabasin 3.91576
HNF4A hepatocyte nuclear factor 4, alpha 3.91576
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 3.91576
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 3.91576
F2RL3 coagulation factor II (thrombin) receptor-like 3 3.91576
NIPAL4 NIPA-like domain containing 4 3.91576
MAB21L2 mab-21-like 2 (C. elegans) 3.91576
CGB1 chorionic gonadotropin, beta polypeptide 1 3.91576
TBX1 T-box 1 3.91576
PCDHGA3 protocadherin gamma subfamily A, 3 3.91576
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 3.91576
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 3.91576
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.91576
IL19 interleukin 19 3.91576
F2RL2 coagulation factor II (thrombin) receptor-like 2 3.91576
WFDC9 WAP four-disulfide core domain 9 3.91576
NEK9 NIMA-related kinase 9 3.91576
TMEM132D transmembrane protein 132D 3.91576
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 3.91576
HAMP hepcidin antimicrobial peptide 3.91576
LCNL1 lipocalin-like 1 3.91576
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.91576
UBQLNL ubiquilin-like 3.91576
NANOGNB NANOG neighbor homeobox 3.91576
CDHR5 cadherin-related family member 5 3.91576
GOLGA6B golgin A6 family, member B 3.91576
IL1B interleukin 1, beta 3.91576
TEKT2 tektin 2 (testicular) 3.91576
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 3.91576
ORM2 orosomucoid 2 3.91576
LY6G6D lymphocyte antigen 6 complex, locus G6D 3.91576
MSMP microseminoprotein, prostate associated 3.91576
GPR149 G protein-coupled receptor 149 3.91576
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.91576
WNT2 wingless-type MMTV integration site family member 2 3.91576
TTC22 tetratricopeptide repeat domain 22 3.91576
GOLGA8R golgin A8 family, member R 3.91576
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 3.91576
SIDT1 SID1 transmembrane family, member 1 3.91576
TPSAB1 tryptase alpha/beta 1 3.91576
CLEC1A C-type lectin domain family 1, member A 3.91576
CFAP47 cilia and flagella associated protein 47 3.91576
UTS2R urotensin 2 receptor 3.91576
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 3.91576
LRTM3 leucine rich repeat transmembrane protein 3 3.91576
BSPH1 binder of sperm protein homolog 1 3.91576
ANKRD55 ankyrin repeat domain 55 3.91576
DLX3 distal-less homeobox 3 3.91576
DAW1 dynein assembly factor with WDR repeat domains 1 3.91576
SLC38A3 solute carrier family 38, member 3 3.91576
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 3.91576
ITGAD integrin, alpha D 3.91576
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 3.91576
ALOX15B arachidonate 15-lipoxygenase, type B 3.91576
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 3.91576
CETP cholesteryl ester transfer protein, plasma 3.91576
RORC RAR-related orphan receptor C 3.91576
IL12B interleukin 12B 3.91576
RERGL RERG/RAS-like 3.91576
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.91576
RHAG Rh-associated glycoprotein 3.91576
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 3.91576
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 3.91576
ZMYND10 zinc finger, MYND-type containing 10 3.91576
ACKR2 atypical chemokine receptor 2 3.91576
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.91576
DISP2 dispatched homolog 2 (Drosophila) 3.91576
REEP4 receptor accessory protein 4 3.91576
SNTN sentan, cilia apical structure protein 3.91576
STAR steroidogenic acute regulatory protein 3.8093
PLA2G10 phospholipase A2, group X 3.8093
MSI1 musashi RNA-binding protein 1 3.80131
PKDCC protein kinase domain containing, cytoplasmic 3.7922
PIEZO2 piezo-type mechanosensitive ion channel component 2 3.60137
MRPS25 mitochondrial ribosomal protein S25 3.58787
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 3.56548
LOXL1 lysyl oxidase-like 1 3.30987
LHX1 LIM homeobox 1 3.27241
SMOC1 SPARC related modular calcium binding 1 3.27241
GOLGA8A golgin A8 family, member A 3.15543
MTMR2 myotubularin related protein 2 3.02798
DNAH14 dynein, axonemal, heavy chain 14 3.01058
TMEM61 transmembrane protein 61 2.91601
SFRP1 secreted frizzled-related protein 1 2.82809
NUP58 nucleoporin 58 2.80129
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 2.78734
RBM4B RNA binding motif protein 4B 2.7827
PNPLA2 patatin-like phospholipase domain containing 2 2.76833
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.7538
MEAK7 MTOR associated protein, eak-7 homolog 2.73864
FYB2 FYN binding protein 2 2.7372
CAPN11 calpain 11 2.7372
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.7372
ACSBG2 acyl-CoA synthetase bubblegum family member 2 2.7372
AP3M1 adaptor-related protein complex 3, mu 1 subunit 2.7372
LDB3 LIM domain binding 3 2.7372
FNDC8 fibronectin type III domain containing 8 2.7372
PRLR prolactin receptor 2.7282
ESRRB estrogen-related receptor beta 2.70616
CWC22 CWC22 spliceosome-associated protein 2.68253
CABIN1 calcineurin binding protein 1 2.68253
KARS1 lysyl-tRNA synthetase 1 2.66525
WWOX WW domain containing oxidoreductase 2.62871
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.62871
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 2.6196
INO80C INO80 complex subunit C 2.60338
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 2.58612
NR6A1 nuclear receptor subfamily 6, group A, member 1 2.57313
WWP2 WW domain containing E3 ubiquitin protein ligase 2 2.55335
OSBPL11 oxysterol binding protein-like 11 2.54372
SAP30 Sin3A-associated protein, 30kDa 2.53104
EHBP1 EH domain binding protein 1 2.52287
IRX2 iroquois homeobox 2 2.5183
FZD8 frizzled class receptor 8 2.51536
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.51338
EML4 echinoderm microtubule associated protein like 4 2.50259
ZNF175 zinc finger protein 175 2.49165
PIP4P2 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2.46644
PTPRA protein tyrosine phosphatase, receptor type, A 2.46413
PRR36 proline rich 36 2.45472
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 2.45472
ZC3HC1 zinc finger, C3HC-type containing 1 2.44597
FRMPD2 FERM and PDZ domain containing 2 2.43862
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.43862
CPZ carboxypeptidase Z 2.43862
PRTG protogenin 2.43182
RASL12 RAS-like, family 12 2.41711
FIZ1 FLT3-interacting zinc finger 1 2.41512
SEZ6 seizure related 6 homolog (mouse) 2.4116
WTAP Wilms tumor 1 associated protein 2.38995
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 2.38537
APEH acylaminoacyl-peptide hydrolase 2.36983
PROCR protein C receptor, endothelial 2.36758
CD8B CD8b molecule 2.36569
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 2.36378
WDR64 WD repeat domain 64 2.36378
RIPOR2 RHO family interacting cell polarization regulator 2 2.36134
S100A4 S100 calcium binding protein A4 2.35358
CCND2 cyclin D2 2.35358
GAB2 GRB2-associated binding protein 2 2.34858
PARD3 par-3 family cell polarity regulator 2.34757
NEFM neurofilament, medium polypeptide 2.34757
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 2.32232
PCNX2 pecanex 2 2.32086
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.31141
PBX1 pre-B-cell leukemia homeobox 1 2.29948
CD46 CD46 molecule, complement regulatory protein 2.29948
SMDT1 single-pass membrane protein with aspartate-rich tail 1 2.29948
TRIM26 tripartite motif containing 26 2.29509
BLACAT1 bladder cancer associated transcript 1 (non-protein coding) 2.29195
CALY calcyon neuron-specific vesicular protein 2.28505
FBLIM1 filamin binding LIM protein 1 2.28505
LRRC61 leucine rich repeat containing 61 2.28505
GPC1 glypican 1 2.28245
PPA2 pyrophosphatase (inorganic) 2 2.28232
ANKRD6 ankyrin repeat domain 6 2.2819
CD24 CD24 molecule 2.2819
ZNF609 zinc finger protein 609 2.28001
LYPD6 LY6/PLAUR domain containing 6 2.2699
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 2.26694
NRIP3 nuclear receptor interacting protein 3 2.26694
H1-1 H1.1 linker histone, cluster member 2.25414
ZNF2 zinc finger protein 2 2.24712
AAMP angio-associated, migratory cell protein 2.23529
PRRX2 paired related homeobox 2 2.20138
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.18792
STAU2 staufen double-stranded RNA binding protein 2 2.18272
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 2.18109
CADM1 cell adhesion molecule 1 2.18109
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 2.17853
CNTNAP3B contactin associated protein-like 3B 2.17078
STK26 serine/threonine protein kinase 26 2.16436
TEAD3 TEA domain family member 3 2.16286
C22ORF15 chromosome 22 open reading frame 15 2.16193
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.16193
KMT5C lysine methyltransferase 5C 2.14629
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.14454
GJC3 gap junction protein, gamma 3, 30.2kDa 2.14296
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 2.14296
MACROD1 MACRO domain containing 1 2.14215
WDR27 WD repeat domain 27 2.12775
BTBD2 BTB (POZ) domain containing 2 2.12775
WNK3 WNK lysine deficient protein kinase 3 2.11589
DRC11 dynein regulatory complex subunit 11 2.10927
KLHL12 kelch-like family member 12 2.1076
SIRT5 sirtuin 5 2.09737
CCDC97 coiled-coil domain containing 97 2.09737
PHOSPHO2 phosphatase, orphan 2 2.08698
MOB2 MOB kinase activator 2 2.08592
TACR3 tachykinin receptor 3 2.08392
ATP5PB ATP synthase peripheral stalk-membrane subunit b 2.08304
HAS3 hyaluronan synthase 3 2.06994
GLRA2 glycine receptor, alpha 2 2.06819
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 2.05746
PTPRM protein tyrosine phosphatase, receptor type, M 2.05564
ACTN1 actinin, alpha 1 2.04512
NUP107 nucleoporin 107kDa 2.0427
RND2 Rho family GTPase 2 2.0427
VAT1L vesicle amine transport 1-like 2.04039
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.04039
ZFC3H1 zinc finger, C3H1-type containing 2.03998
DUSP5 dual specificity phosphatase 5 2.03749
CCDC142 coiled-coil domain containing 142 2.02306
ZNF75A zinc finger protein 75a 2.0186
COTL1 coactosin-like F-actin binding protein 1 2.01399
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 2.00905
CCDC175 coiled-coil domain containing 175 2.00846
KCTD7 potassium channel tetramerization domain containing 7 2.00116

decreased expression

Symbol Name Standardized Value
UPK1A uroplakin 1A -3.91576
SKIL SKI-like proto-oncogene -3.91576
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -3.91576
RPS8 ribosomal protein S8 -3.91576
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 -3.91576
CXCR4 chemokine (C-X-C motif) receptor 4 -3.91576
IZUMO1 izumo sperm-egg fusion 1 -3.91576
STRIT1 small transmembrane regulator of ion transport 1 -3.91576
CCDC17 coiled-coil domain containing 17 -3.91576
ANKRD53 ankyrin repeat domain 53 -3.91576
TEX101 testis expressed 101 -3.91576
LGALS14 lectin, galactoside-binding, soluble, 14 -3.91576
ZNF599 zinc finger protein 599 -3.91576
GARIN6 golgi associated RAB2 interactor family member 6 -3.91576
TERB1 telomere repeat binding bouquet formation protein 1 -3.91576
ZNF804B zinc finger protein 804B -3.91576
DLX4 distal-less homeobox 4 -3.91576
LEP leptin -3.91576
RASA4 RAS p21 protein activator 4 -3.91576
AGA-DT AGA divergent transcript -3.91576
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -3.91576
CRYGB crystallin, gamma B -3.91576
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) -3.91576
TMEM238L transmembrane protein 238 like -3.91576
GPC6 glypican 6 -3.91179
C2CD3 C2 calcium-dependent domain containing 3 -3.76658
CIDEB cell death-inducing DFFA-like effector b -3.6733
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 -3.58787
S100A11 S100 calcium binding protein A11 -3.58787
SOCS1 suppressor of cytokine signaling 1 -3.56934
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -3.51198
ACVR1 activin A receptor, type I -3.37157
ANXA2 annexin A2 -3.32218
RPL38 ribosomal protein L38 -3.31845
MAN2A1 mannosidase, alpha, class 2A, member 1 -3.29059
RCAN2 regulator of calcineurin 2 -3.281
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -3.27241
TPM1 tropomyosin 1 (alpha) -3.23728
MGAT4C MGAT4 family, member C -3.19433
SMIM18 small integral membrane protein 18 -3.19433
KIFAP3 kinesin-associated protein 3 -3.19433
SCGB3A2 secretoglobin, family 3A, member 2 -3.18813
TP73 tumor protein p73 -3.14794
OPRM1 opioid receptor, mu 1 -3.14008
AMIGO1 adhesion molecule with Ig-like domain 1 -3.14008
RPL35 ribosomal protein L35 -3.12586
PRICKLE1 prickle homolog 1 (Drosophila) -3.0884
KIAA0825 KIAA0825 -3.07278
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -3.04749
EIF2D eukaryotic translation initiation factor 2D -3.02756
PEX39 peroxisomal biogenesis factor 39 -3.02142
UNC93B1 unc-93 homolog B1 (C. elegans) -3.01617
RBMS2 RNA binding motif, single stranded interacting protein 2 -3.00879
BMPR1A bone morphogenetic protein receptor, type IA -2.98855
N4BP1 NEDD4 binding protein 1 -2.98102
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 -2.96693
NHSL1 NHS-like 1 -2.96693
NUDCD3 NudC domain containing 3 -2.96658
RESF1 retroelement silencing factor 1 -2.95701
SYT4 synaptotagmin IV -2.9425
TMEM106C transmembrane protein 106C -2.91947
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.91947
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.87767
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 -2.8775
LPAR3 lysophosphatidic acid receptor 3 -2.82809
SNRPN small nuclear ribonucleoprotein polypeptide N -2.82143
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -2.81431
C1ORF52 chromosome 1 open reading frame 52 -2.8088
PDCL phosducin-like -2.80805
TTC39C tetratricopeptide repeat domain 39C -2.79844
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -2.78734
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -2.78423
SYNGR2 synaptogyrin 2 -2.78206
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.7708
PHF21B PHD finger protein 21B -2.7708
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.73864
MCPH1 microcephalin 1 -2.7372
RPS16 ribosomal protein S16 -2.7282
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.69688
BAG4 BCL2-associated athanogene 4 -2.68253
SPRYD7 SPRY domain containing 7 -2.66296
LIG4 ligase IV, DNA, ATP-dependent -2.636
S100A10 S100 calcium binding protein A10 -2.63274
S1PR5 sphingosine-1-phosphate receptor 5 -2.62507
ACOT13 acyl-CoA thioesterase 13 -2.62233
AFG3L2 AFG3-like AAA ATPase 2 -2.58774
RGL3 ral guanine nucleotide dissociation stimulator-like 3 -2.56542
REX1BD required for excision 1-B domain containing -2.55608
EXO1 exonuclease 1 -2.55608
ADAM15 ADAM metallopeptidase domain 15 -2.55335
ANGPT1 angiopoietin 1 -2.54898
ADAM28 ADAM metallopeptidase domain 28 -2.54372
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.53634
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -2.50879
GNMT glycine N-methyltransferase -2.5054
MAGED2 melanoma antigen family D2 -2.5054
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -2.50338
MSH2 mutS homolog 2 -2.50338
RBP5 retinol binding protein 5, cellular -2.49015
KREMEN2 kringle containing transmembrane protein 2 -2.4739
RPL39 ribosomal protein L39 -2.45829
PNMA2 paraneoplastic Ma antigen 2 -2.45399
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -2.44427
IFITM1 interferon induced transmembrane protein 1 -2.43604
H4C2 H4 clustered histone 2 -2.42594
HCLS1 hematopoietic cell-specific Lyn substrate 1 -2.41512
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -2.41512
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -2.41314
RUNX2 runt-related transcription factor 2 -2.407
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.37892
ANKRD24 ankyrin repeat domain 24 -2.36734
VSTM2L V-set and transmembrane domain containing 2 like -2.36569
VSTM2A V-set and transmembrane domain containing 2A -2.36569
SPART spartin -2.36378
PDLIM1 PDZ and LIM domain 1 -2.35448
TRIM14 tripartite motif containing 14 -2.3503
GPC4 glypican 4 -2.3503
NEIL1 nei endonuclease VIII-like 1 (E. coli) -2.34858
ELOB elongin B -2.34757
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -2.34509
SLC25A39 solute carrier family 25, member 39 -2.34297
RPLP2 ribosomal protein, large, P2 -2.33858
CLSTN3 calsyntenin 3 -2.33533
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.30707
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -2.30595
USP53 ubiquitin specific peptidase 53 -2.29135
COL5A2 collagen, type V, alpha 2 -2.28935
PAOX polyamine oxidase (exo-N4-amino) -2.28505
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -2.28505
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -2.26694
CKMT1A creatine kinase, mitochondrial 1A -2.26283
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.23529
IPMK inositol polyphosphate multikinase -2.22903
RIOK3 RIO kinase 3 -2.22304
RASA2 RAS p21 protein activator 2 -2.21964
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.2102
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.2079
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta -2.2046
GCN1 GCN1 activator of EIF2AK4 -2.19547
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -2.19393
UBE2B ubiquitin-conjugating enzyme E2B -2.19231
KLHDC3 kelch domain containing 3 -2.19093
DCC DCC netrin 1 receptor -2.19044
BMP2K BMP2 inducible kinase -2.19044
ADGRB3 adhesion G protein-coupled receptor B3 -2.19044
KLC4 kinesin light chain 4 -2.18109
SP110 SP110 nuclear body protein -2.18099
LIG1 ligase I, DNA, ATP-dependent -2.17207
MRAS muscle RAS oncogene homolog -2.17123
EXD2 exonuclease 3'-5' domain containing 2 -2.16193
TMEM63A transmembrane protein 63A -2.15986
SCO2 SCO2 cytochrome c oxidase assembly protein -2.15842
GLB1 galactosidase, beta 1 -2.14654
NODAL nodal growth differentiation factor -2.13239
WTIP Wilms tumor 1 interacting protein -2.13239
MRPL32 mitochondrial ribosomal protein L32 -2.12775
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -2.11975
XBP1 X-box binding protein 1 -2.11514
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -2.1076
CCDC80 coiled-coil domain containing 80 -2.1076
CNTLN centlein, centrosomal protein -2.10106
IFT70A intraflagellar transport 70A -2.09935
DNAH1 dynein, axonemal, heavy chain 1 -2.09935
ISG15 ISG15 ubiquitin-like modifier -2.09737
LPAR1 lysophosphatidic acid receptor 1 -2.09737
COX19 COX19 cytochrome c oxidase assembly factor -2.09737
GLIS2 GLIS family zinc finger 2 -2.0934
CAPG capping protein (actin filament), gelsolin-like -2.07858
DPH7 diphthamide biosynthesis 7 -2.07237
POM121C POM121 transmembrane nucleoporin C -2.07237
ELMOD3 ELMO/CED-12 domain containing 3 -2.06958
TBRG4 transforming growth factor beta regulator 4 -2.06598
NFXL1 nuclear transcription factor, X-box binding-like 1 -2.05757
DIPK1B divergent protein kinase domain 1B -2.05564
GAP43 growth associated protein 43 -2.05357
TENT4B terminal nucleotidyltransferase 4B -2.05324
RPL28 ribosomal protein L28 -2.0515
CRCP CGRP receptor component -2.05065
STOX2 storkhead box 2 -2.04678
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 -2.0427
POU5F1 POU class 5 homeobox 1 -2.0427
ADORA2A adenosine A2a receptor -2.03998
CDAN1 codanin 1 -2.03377
ZNF420 zinc finger protein 420 -2.02498
FMO5 flavin containing monooxygenase 5 -2.02321
TMEM209 transmembrane protein 209 -2.0215
MRPL12 mitochondrial ribosomal protein L12 -2.02105
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.01735
TULP2 tubby like protein 2 -2.00905
MIEF2 mitochondrial elongation factor 2 -2.00905
CTSL cathepsin L -2.00846
ANKRD9 ankyrin repeat domain 9 -2.00753
SMIM12 small integral membrane protein 12 -2.00077