TGFBR2 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description transforming growth factor, beta receptor II (70/80kDa)|This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7048)
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100 substrates of the kinase TGFBR2 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
CENPF centromere protein F, 350/400kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
LMO7 LIM domain 7
PPP1R18 protein phosphatase 1, regulatory subunit 18
MFF mitochondrial fission factor
BACE2 beta-site APP-cleaving enzyme 2
PVRL4 poliovirus receptor-related 4
ENTHD2 ENTH domain containing 2
CEP68 centrosomal protein 68kDa
AKAP13 A kinase (PRKA) anchor protein 13
CD5 CD5 molecule
TTN titin
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2
PSIP1 PC4 and SFRS1 interacting protein 1
CABIN1 calcineurin binding protein 1
RASIP1 Ras interacting protein 1
SPAG9 sperm associated antigen 9
WIZ widely interspaced zinc finger motifs
BCR breakpoint cluster region
UBE2O ubiquitin-conjugating enzyme E2O
STX7 syntaxin 7
CIT citron rho-interacting serine/threonine kinase
TJP1 tight junction protein 1
MKI67 marker of proliferation Ki-67
RNF10 ring finger protein 10
PIGR polymeric immunoglobulin receptor
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B
SFPQ splicing factor proline/glutamine-rich
MYO18A myosin XVIIIA
LTV1 LTV1 ribosome biogenesis factor
ABR active BCR-related
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
YIPF5 Yip1 domain family, member 5
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
ARFIP2 ADP-ribosylation factor interacting protein 2
IGF1R insulin-like growth factor 1 receptor
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
AHNAK AHNAK nucleoprotein
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
PTPRF protein tyrosine phosphatase, receptor type, F
MLPH melanophilin
COL1A1 collagen, type I, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
GRB2 growth factor receptor-bound protein 2
ICE1 interactor of little elongation complex ELL subunit 1
NHSL2 NHS-like 2
PABPC1 poly(A) binding protein, cytoplasmic 1
BTBD7 BTB (POZ) domain containing 7
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
TICRR TOPBP1-interacting checkpoint and replication regulator
RSF1 remodeling and spacing factor 1
NCAPH2 non-SMC condensin II complex, subunit H2
PHF3 PHD finger protein 3
CNOT12 CCR4-NOT transcription complex subunit 12
MAT2B methionine adenosyltransferase II, beta
AQP8 aquaporin 8
TP53BP1 tumor protein p53 binding protein 1
FLNA filamin A, alpha
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
FANCA Fanconi anemia, complementation group A
VPS13B vacuolar protein sorting 13 homolog B (yeast)
FKBP15 FK506 binding protein 15, 133kDa
MAP1A microtubule-associated protein 1A
CCP110 centriolar coiled coil protein 110kDa
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
RIN1 Ras and Rab interactor 1
ABLIM3 actin binding LIM protein family, member 3
WDR17 WD repeat domain 17
ANAPC5 anaphase promoting complex subunit 5
RIF1 replication timing regulatory factor 1
SRRM2 serine/arginine repetitive matrix 2
LMNA lamin A/C
UBR4 ubiquitin protein ligase E3 component n-recognin 4
CAPZB capping protein (actin filament) muscle Z-line, beta
EIF3A eukaryotic translation initiation factor 3, subunit A
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PARD3B par-3 family cell polarity regulator beta
BPTF bromodomain PHD finger transcription factor
ZNF407 zinc finger protein 407
DEF6 differentially expressed in FDCP 6 homolog (mouse)
PIEZO2 piezo-type mechanosensitive ion channel component 2
CTTN cortactin
TRPM7 transient receptor potential cation channel, subfamily M, member 7
NCAPH non-SMC condensin I complex, subunit H
CEP170 centrosomal protein 170kDa
STAB2 stabilin 2
CLK2 CDC-like kinase 2
SOGA1 suppressor of glucose, autophagy associated 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
DMTN dematin actin binding protein
KIAA1468 KIAA1468
LOC113230 uncharacterized protein LOC113230
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
TXNDC17 thioredoxin domain containing 17