| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | transforming growth factor, beta receptor II (70/80kDa)|This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7048) |
| External Link | https://ncbi.nlm.nih.gov/gene/7048 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TGFBR2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 0.0392016 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.0391562 |
| S100A7 | S100 calcium binding protein A7 | 0.0389089 |
| HOPX | HOP homeobox | 0.0351735 |
| PFKL | phosphofructokinase, liver | 0.0328636 |
| PKM | pyruvate kinase, muscle | 0.0326896 |
| MEF2C | myocyte enhancer factor 2C | 0.031 |
| PLPP3 | phospholipid phosphatase 3 | 0.0297263 |
| LCN2 | lipocalin 2 | 0.0291061 |
| INSIG1 | insulin induced gene 1 | 0.0285222 |
| VEGFA | vascular endothelial growth factor A | 0.0284378 |
| PFKP | phosphofructokinase, platelet | 0.0283806 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0281939 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0279301 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0278778 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.026552 |
| RPIA | ribose 5-phosphate isomerase A | 0.0263575 |
| CHKB | choline kinase beta | 0.0261793 |
| EPHB2 | EPH receptor B2 | 0.0260374 |
| RGCC | regulator of cell cycle | 0.0259145 |
| CD9 | CD9 molecule | 0.0258723 |
| DACH1 | dachshund family transcription factor 1 | 0.0256144 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0255005 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0254704 |
| EPN2 | epsin 2 | 0.0253653 |
| TUBA1A | tubulin, alpha 1a | 0.0251702 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.025126 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.0251029 |
| AK4 | adenylate kinase 4 | 0.0250439 |
| H1-10 | H1.10 linker histone | 0.0245218 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.0245155 |
| PROM1 | prominin 1 | 0.0240618 |
| TYRP1 | tyrosinase-related protein 1 | 0.0239558 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0239548 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.0238098 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0237891 |
| CRIP2 | cysteine-rich protein 2 | 0.0237864 |
| GOLT1B | golgi transport 1B | 0.0236856 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0236789 |
| MLF1 | myeloid leukemia factor 1 | 0.0230819 |
| GRAMD1C | GRAM domain containing 1C | 0.022943 |
| SQOR | sulfide quinone oxidoreductase | 0.0229321 |
| KLK6 | kallikrein-related peptidase 6 | 0.0228881 |
| DEFB1 | defensin, beta 1 | 0.0228313 |
| MSLN | mesothelin | 0.0227948 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.022652 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.0226477 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0225909 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.0225471 |
| HMGB3 | high mobility group box 3 | 0.0224407 |
| CST6 | cystatin E/M | 0.0223759 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0223467 |
| ADIRF | adipogenesis regulatory factor | 0.0222795 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.0222648 |
| DNTT | DNA nucleotidylexotransferase | 0.0221508 |
| FASN | fatty acid synthase | 0.0221234 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.0220606 |
| ENO1 | enolase 1, (alpha) | 0.0217395 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0217218 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.0217067 |
| SMAD6 | SMAD family member 6 | 0.0215435 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0211715 |
| GPX1 | glutathione peroxidase 1 | 0.0209235 |
| CCNB2 | cyclin B2 | 0.0208958 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.0208104 |
| FOXF1 | forkhead box F1 | 0.0207712 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0206251 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.020413 |
| TSPAN12 | tetraspanin 12 | 0.020232 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0200012 |
| CCDC92 | coiled-coil domain containing 92 | 0.0199605 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.0199246 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0199001 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.0196492 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.0196397 |
| GPSM2 | G-protein signaling modulator 2 | 0.0194438 |
| EFNB2 | ephrin-B2 | 0.0192717 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0191685 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0190795 |
| KLHL23 | kelch-like family member 23 | 0.0190633 |
| FHL1 | four and a half LIM domains 1 | 0.0189443 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0188949 |
| RAPSN | receptor-associated protein of the synapse | 0.0188789 |
| KLK11 | kallikrein-related peptidase 11 | 0.0188469 |
| FOLR1 | folate receptor 1 (adult) | 0.018794 |
| IL10RB | interleukin 10 receptor, beta | 0.0187465 |
| CLDN3 | claudin 3 | 0.0186408 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0186234 |
| LTA4H | leukotriene A4 hydrolase | 0.0185854 |
| PGK1 | phosphoglycerate kinase 1 | 0.018573 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0184697 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0184672 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0184087 |
| TNS3 | tensin 3 | 0.0184039 |
| HLTF | helicase-like transcription factor | 0.0183876 |
| MYLIP | myosin regulatory light chain interacting protein | 0.0183807 |
| KLF10 | Kruppel-like factor 10 | 0.0183155 |
| AREG | amphiregulin | 0.0183083 |
| ANXA5 | annexin A5 | 0.0181906 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0181893 |
| RRAGD | Ras-related GTP binding D | 0.0181857 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.0181779 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.0181138 |
| MCM2 | minichromosome maintenance complex component 2 | 0.0180364 |
| KLK8 | kallikrein-related peptidase 8 | 0.018028 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0179713 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0179532 |
| NMU | neuromedin U | 0.0179467 |
| HMGB2 | high mobility group box 2 | 0.017926 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.0178424 |
| TCF4 | transcription factor 4 | 0.0178003 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.0177814 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0177642 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0177433 |
| LAMA5 | laminin, alpha 5 | 0.0177384 |
| PRKD1 | protein kinase D1 | 0.017637 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.0175245 |
| KLK7 | kallikrein-related peptidase 7 | 0.0175202 |
| SCARA3 | scavenger receptor class A, member 3 | 0.0174717 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0174169 |
| ATF3 | activating transcription factor 3 | 0.0174155 |
| CUEDC1 | CUE domain containing 1 | 0.0172326 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0171054 |
| OLFM4 | olfactomedin 4 | 0.0170998 |
| COL6A1 | collagen, type VI, alpha 1 | 0.017098 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0170967 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.0170659 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0170555 |
| BARD1 | BRCA1 associated RING domain 1 | 0.0170456 |
| LDB2 | LIM domain binding 2 | 0.0170374 |
| TSPYL5 | TSPY-like 5 | 0.0169708 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.0169507 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0169198 |
| SRP54 | signal recognition particle 54kDa | 0.0168884 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0168652 |
| H1-0 | H1.0 linker histone | 0.0167872 |
| TNS1 | tensin 1 | 0.0167378 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0167225 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.0166361 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0165857 |
| DEK | DEK proto-oncogene | 0.0165458 |
| CFAP69 | cilia and flagella associated protein 69 | 0.0165406 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0165096 |
| ADK | adenosine kinase | 0.0164375 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0164347 |
| HPCAL1 | hippocalcin-like 1 | 0.016408 |
| ANXA3 | annexin A3 | 0.0163618 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.0163566 |
| CS | citrate synthase | 0.0163484 |
| SOSTDC1 | sclerostin domain containing 1 | 0.0162508 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0162375 |
| EMP2 | epithelial membrane protein 2 | 0.0162309 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.0161827 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0161229 |
| NPY | neuropeptide Y | 0.0161105 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0161079 |
| MUC16 | mucin 16, cell surface associated | 0.016082 |
| PRR7 | proline rich 7 (synaptic) | 0.0160556 |
| TMEM45A | transmembrane protein 45A | 0.0160266 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0160183 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0160143 |
| FSTL1 | follistatin-like 1 | 0.0159881 |
| PCNA | proliferating cell nuclear antigen | 0.0158713 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0158664 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0158505 |
| F2R | coagulation factor II (thrombin) receptor | 0.0158378 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0158089 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 0.0158076 |
| CCNF | cyclin F | 0.0157701 |
| S100A2 | S100 calcium binding protein A2 | 0.0156691 |
| PALMD | palmdelphin | 0.0156323 |
| MATN2 | matrilin 2 | 0.015626 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0156258 |
| CRNN | cornulin | 0.0155149 |
| GPX3 | glutathione peroxidase 3 | 0.0154753 |
| EREG | epiregulin | 0.015428 |
| TOX | thymocyte selection-associated high mobility group box | 0.0154209 |
| FADS1 | fatty acid desaturase 1 | 0.0153952 |
| MACROD1 | MACRO domain containing 1 | 0.0153304 |
| PRPF4 | pre-mRNA processing factor 4 | 0.015304 |
| CUX2 | cut-like homeobox 2 | 0.0152978 |
| NREP | neuronal regeneration related protein | 0.0152863 |
| TMSB15A | thymosin beta 15a | 0.0152826 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.0152684 |
| SVIL | supervillin | 0.0152645 |
| MAGED1 | melanoma antigen family D1 | 0.0152354 |
| DIO2 | deiodinase, iodothyronine, type II | 0.0151828 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0151813 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | 0.0151682 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.0151413 |
| CYRIA | CYFIP related Rac1 interactor A | 0.0151113 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.0150899 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0150531 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0150492 |
| TGM1 | transglutaminase 1 | 0.0150238 |
| RNF43 | ring finger protein 43 | 0.0149595 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0149022 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.0148965 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0148882 |
| FRMD4B | FERM domain containing 4B | 0.0148784 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0148762 |
| PGD | phosphogluconate dehydrogenase | 0.0148661 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0148628 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0148092 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0147991 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0147852 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0147548 |
| NIPSNAP2 | nipsnap homolog 2 | 0.014727 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0147162 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.0147116 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0146849 |
| ADD3 | adducin 3 (gamma) | 0.0146505 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.0146406 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0145979 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | 0.0145598 |
| FZD10 | frizzled class receptor 10 | 0.0145344 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0144848 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0144803 |
| ITM2A | integral membrane protein 2A | 0.014454 |
| CENPU | centromere protein U | 0.0143464 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.0143442 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0143283 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0143254 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0142855 |
| MCM6 | minichromosome maintenance complex component 6 | 0.0142805 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.0142789 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0142678 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0142641 |
| IPP | intracisternal A particle-promoted polypeptide | 0.0142413 |
| MYO5C | myosin VC | 0.0142344 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.014225 |
| COL1A2 | collagen, type I, alpha 2 | 0.0142249 |
| IFT81 | intraflagellar transport 81 | 0.0142137 |
| NDRG1 | N-myc downstream regulated 1 | 0.0142049 |
| RAB38 | RAB38, member RAS oncogene family | 0.0141695 |
| ALAD | aminolevulinate dehydratase | 0.0141395 |
| FOXC1 | forkhead box C1 | 0.0141023 |
| YPEL1 | yippee-like 1 (Drosophila) | 0.0140648 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0140566 |
| PCGF2 | polycomb group ring finger 2 | 0.0140449 |
| ATXN1 | ataxin 1 | 0.0140422 |
| PTMS | parathymosin | 0.0139952 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0139885 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0139658 |
| SSPN | sarcospan | 0.0139463 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.013942 |
| AGRN | agrin | 0.0139323 |
| SRGN | serglycin | 0.0139001 |
| SMYD3 | SET and MYND domain containing 3 | 0.0138982 |
| TXN | thioredoxin | 0.0138981 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.0477171 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0391316 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.0389532 |
| CD163 | CD163 molecule | -0.0340502 |
| C3 | complement component 3 | -0.0339381 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0331729 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0331136 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0323024 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0318631 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0318434 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0317882 |
| HOXC6 | homeobox C6 | -0.0308465 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0301613 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.0299525 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0297315 |
| MEN1 | multiple endocrine neoplasia I | -0.0295865 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0285392 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0285038 |
| DCLK1 | doublecortin-like kinase 1 | -0.0280791 |
| RTN1 | reticulon 1 | -0.0278939 |
| PLXNC1 | plexin C1 | -0.0276771 |
| AGTR1 | angiotensin II receptor, type 1 | -0.0276338 |
| STAB1 | stabilin 1 | -0.0269652 |
| TNC | tenascin C | -0.0269562 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0267682 |
| ANXA10 | annexin A10 | -0.0266028 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.0262898 |
| TFF1 | trefoil factor 1 | -0.0256116 |
| GATA3 | GATA binding protein 3 | -0.0255814 |
| TLR4 | toll-like receptor 4 | -0.0255468 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0251664 |
| NLGN4X | neuroligin 4, X-linked | -0.0251416 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0249182 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0246601 |
| AIM2 | absent in melanoma 2 | -0.0246408 |
| FOXO1 | forkhead box O1 | -0.0245536 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0245163 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0241667 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.024013 |
| GAP43 | growth associated protein 43 | -0.0239979 |
| SYT1 | synaptotagmin I | -0.0234848 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0233658 |
| TAC1 | tachykinin, precursor 1 | -0.0233397 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0232151 |
| PRDX2 | peroxiredoxin 2 | -0.0232068 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0231286 |
| GCH1 | GTP cyclohydrolase 1 | -0.0231277 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0229884 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0227263 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0227175 |
| MFAP5 | microfibrillar associated protein 5 | -0.0225514 |
| CTSE | cathepsin E | -0.0224617 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0224316 |
| S100B | S100 calcium binding protein B | -0.0222927 |
| CHGB | chromogranin B | -0.0221825 |
| CHEK2 | checkpoint kinase 2 | -0.0219935 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0219023 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0215255 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0213823 |
| CA12 | carbonic anhydrase XII | -0.0213382 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.021322 |
| CALB1 | calbindin 1, 28kDa | -0.0212401 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0212042 |
| FYB1 | FYN binding protein 1 | -0.0210987 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0210936 |
| CSF1R | colony stimulating factor 1 receptor | -0.0209331 |
| TMEM176B | transmembrane protein 176B | -0.0207417 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0207006 |
| TPD52L1 | tumor protein D52-like 1 | -0.0206447 |
| QDPR | quinoid dihydropteridine reductase | -0.0204951 |
| MOCOS | molybdenum cofactor sulfurase | -0.0204797 |
| TLR2 | toll-like receptor 2 | -0.0204404 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0203287 |
| L1CAM | L1 cell adhesion molecule | -0.0203212 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.0203062 |
| RND3 | Rho family GTPase 3 | -0.0202739 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0202389 |
| HMOX1 | heme oxygenase 1 | -0.0201545 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.0201087 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -0.0200336 |
| C1S | complement component 1, s subcomponent | -0.0198736 |
| KIF5C | kinesin family member 5C | -0.0198646 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0197298 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0196894 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.019646 |
| MAP7 | microtubule-associated protein 7 | -0.0195993 |
| MIA | melanoma inhibitory activity | -0.0195859 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.0194556 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.0193796 |
| STMN2 | stathmin 2 | -0.0193766 |
| ITK | IL2-inducible T-cell kinase | -0.0193684 |
| VSNL1 | visinin-like 1 | -0.0193328 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0192603 |
| ITGA6 | integrin, alpha 6 | -0.0192286 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.0191052 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0190646 |
| THBS2 | thrombospondin 2 | -0.0190509 |
| TFF2 | trefoil factor 2 | -0.0189464 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.018775 |
| GNLY | granulysin | -0.0186328 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.018511 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.0185078 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0184466 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0184173 |
| OLFML2B | olfactomedin-like 2B | -0.0184091 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0183416 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.0182993 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0182421 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.0182076 |
| HOXB6 | homeobox B6 | -0.0181854 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | -0.0181749 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0179497 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0179034 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0178435 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.0177812 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0177105 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0177031 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -0.0176951 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0176596 |
| C4BPB | complement component 4 binding protein, beta | -0.0176006 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0175863 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0174179 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.0174008 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.0173985 |
| FCGBP | Fc fragment of IgG binding protein | -0.0173913 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0173735 |
| C4BPA | complement component 4 binding protein, alpha | -0.0173569 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0172942 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.0172717 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.0171191 |
| NTS | neurotensin | -0.017115 |
| STK10 | serine/threonine kinase 10 | -0.0170852 |
| TMEM110 | transmembrane protein 110 | -0.0170764 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0170268 |
| C3AR1 | complement component 3a receptor 1 | -0.017009 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0169861 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0169515 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.0169477 |
| ABHD3 | abhydrolase domain containing 3 | -0.0168861 |
| CDC25B | cell division cycle 25B | -0.0168787 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0168536 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.0168131 |
| GPR88 | G protein-coupled receptor 88 | -0.0168109 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.0167927 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.0167538 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0166685 |
| FGF13 | fibroblast growth factor 13 | -0.0166633 |
| ADRA2A | adrenoceptor alpha 2A | -0.0166553 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0166528 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.0165876 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.0165723 |
| APOC1 | apolipoprotein C-I | -0.0165406 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0164382 |
| RETREG1 | reticulophagy regulator 1 | -0.0164154 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.0164129 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0163767 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0163573 |
| IL16 | interleukin 16 | -0.016329 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0163288 |
| RUNX3 | runt-related transcription factor 3 | -0.0162693 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0162255 |
| CD2 | CD2 molecule | -0.0161797 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.0161755 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.0161121 |
| MXRA5 | matrix-remodelling associated 5 | -0.016046 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0160383 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.0160361 |
| PRAME | preferentially expressed antigen in melanoma | -0.0159788 |
| TRIM22 | tripartite motif containing 22 | -0.015942 |
| GPX2 | glutathione peroxidase 2 | -0.015925 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.0158765 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | -0.0158706 |
| FDX1 | ferredoxin 1 | -0.0158631 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0158314 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0158209 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0158202 |
| NNMT | nicotinamide N-methyltransferase | -0.0158076 |
| LPIN1 | lipin 1 | -0.0157897 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.0157493 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -0.0157423 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.0157406 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0157329 |
| GUCY2C | guanylate cyclase 2C | -0.0157318 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0157037 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.0156543 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.0155878 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0155866 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.0154774 |
| ADORA3 | adenosine A3 receptor | -0.0154507 |
| R3HDM4 | R3H domain containing 4 | -0.0154059 |
| NELL2 | NEL-like 2 (chicken) | -0.0153907 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0153894 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.0153422 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0153395 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0153012 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.0152786 |
| MEST | mesoderm specific transcript | -0.015232 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.0151906 |
| LTF | lactotransferrin | -0.0151715 |
| APOL6 | apolipoprotein L, 6 | -0.0151316 |
| ESR1 | estrogen receptor 1 | -0.015101 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.0150951 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.0150792 |
| HEATR1 | HEAT repeat containing 1 | -0.0149966 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | -0.0149677 |
| FAM198B | family with sequence similarity 198, member B | -0.0149607 |
| LRP5L | low density lipoprotein receptor-related protein 5-like | -0.0149593 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.0149503 |
| RPS27L | ribosomal protein S27-like | -0.0149347 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.0148523 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.0148406 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0148372 |
| CA2 | carbonic anhydrase II | -0.0148353 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0148224 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0148105 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.0147318 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.014731 |
| RPS17 | ribosomal protein S17 | -0.0147257 |
| FPR1 | formyl peptide receptor 1 | -0.0147167 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.014684 |
| MFAP2 | microfibrillar-associated protein 2 | -0.014673 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.0146652 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.01464 |
| PTHLH | parathyroid hormone-like hormone | -0.0146112 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.0145809 |
| NOP2 | NOP2 nucleolar protein | -0.0145443 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | -0.0145212 |
| PLP1 | proteolipid protein 1 | -0.0144706 |
| A2M | alpha-2-macroglobulin | -0.014455 |
| WDR45 | WD repeat domain 45 | -0.0144477 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0144273 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0143992 |
| CLU | clusterin | -0.0143589 |
| C1R | complement component 1, r subcomponent | -0.0142682 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0142621 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | -0.0142558 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.0142516 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.014225 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.0142246 |
| CD14 | CD14 molecule | -0.0142099 |
| PRPH | peripherin | -0.014206 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0141904 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0141696 |
| HOXB7 | homeobox B7 | -0.0141663 |
| MSX1 | msh homeobox 1 | -0.014159 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0141455 |
| GKN1 | gastrokine 1 | -0.0141329 |
| DST | dystonin | -0.0141323 |
| TFR2 | transferrin receptor 2 | -0.0141305 |
| LRRC31 | leucine rich repeat containing 31 | -0.0141237 |
