TGFBR3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transforming growth factor, beta receptor III|This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 7049)
External Link https://ncbi.nlm.nih.gov/gene/7049
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Genes

500 genes differentially expressed following the TGFBR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0195716
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0138151
NELL2 NEL-like 2 (chicken) 0.0136354
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0124845
TUBB2A tubulin, beta 2A class IIa 0.0120187
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0116288
MMP12 matrix metallopeptidase 12 0.0114858
NTS neurotensin 0.0114165
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.0113116
CCNB1 cyclin B1 0.0112608
CLCA1 chloride channel accessory 1 0.0111848
TNNT1 troponin T type 1 (skeletal, slow) 0.0110701
TMSB15A thymosin beta 15a 0.0103495
SUB1 SUB1 homolog (S. cerevisiae) 0.0101079
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0100734
MDFIC MyoD family inhibitor domain containing 0.00989799
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00984912
WDR61 WD repeat domain 61 0.00984309
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00982692
CANT1 calcium activated nucleotidase 1 0.00980135
GLO1 glyoxalase I 0.00978574
TBC1D31 TBC1 domain family, member 31 0.00974762
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00952672
GJA1 gap junction protein, alpha 1, 43kDa 0.00949978
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00947098
CD99 CD99 molecule 0.00946674
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00929919
TMEM14A transmembrane protein 14A 0.00927944
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00925158
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00910485
DCXR dicarbonyl/L-xylulose reductase 0.00898596
TCTA T-cell leukemia translocation altered 0.00893231
LGALS13 lectin, galactoside-binding, soluble, 13 0.00892804
SELENBP1 selenium binding protein 1 0.00889324
ECI2 enoyl-CoA delta isomerase 2 0.00883418
TFF1 trefoil factor 1 0.00882568
CHKB choline kinase beta 0.00873562
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00869887
TSPAN6 tetraspanin 6 0.00869743
NPM3 nucleophosmin/nucleoplasmin 3 0.00865241
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00865237
SORD sorbitol dehydrogenase 0.00863281
HNMT histamine N-methyltransferase 0.00852454
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00851537
LGALS4 lectin, galactoside-binding, soluble, 4 0.00849791
CCK cholecystokinin 0.0084761
FAM3C family with sequence similarity 3, member C 0.00846662
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00840847
TMC5 transmembrane channel-like 5 0.00833437
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00832488
ADORA2B adenosine A2b receptor 0.00825583
KDM5D lysine (K)-specific demethylase 5D 0.00822846
KIF20A kinesin family member 20A 0.00818577
DUOX2 dual oxidase 2 0.00799336
DPYD dihydropyrimidine dehydrogenase 0.00796353
TMEM14B transmembrane protein 14B 0.00795106
CD320 CD320 molecule 0.00790208
GSTT1 glutathione S-transferase theta 1 0.00784462
SPON2 spondin 2, extracellular matrix protein 0.00781247
GNLY granulysin 0.00777957
SEPP1 selenoprotein P, plasma, 1 0.0077353
FCGBP Fc fragment of IgG binding protein 0.00769688
SIRT3 sirtuin 3 0.00765103
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00759354
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00758934
IDO1 indoleamine 2,3-dioxygenase 1 0.007547
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00753044
ACP5 acid phosphatase 5, tartrate resistant 0.0075274
RGS10 regulator of G-protein signaling 10 0.00751907
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00750028
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00749436
FZD5 frizzled class receptor 5 0.00749249
TSPAN7 tetraspanin 7 0.00745079
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00741994
GCLC glutamate-cysteine ligase, catalytic subunit 0.00741653
CALML4 calmodulin-like 4 0.00740684
GTPBP8 GTP-binding protein 8 (putative) 0.00736932
FABP1 fatty acid binding protein 1, liver 0.00735859
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00735457
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.00731773
ATP10B ATPase, class V, type 10B 0.00729627
SPINK4 serine peptidase inhibitor, Kazal type 4 0.0072809
STAT4 signal transducer and activator of transcription 4 0.00726528
JPT1 Jupiter microtubule associated homolog 1 0.00721716
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00716009
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00708173
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00702919
C3ORF14 chromosome 3 open reading frame 14 0.00701046
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.0070028
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.00699296
MSMB microseminoprotein, beta- 0.00694612
IL2RG interleukin 2 receptor, gamma 0.00693543
CD2 CD2 molecule 0.00692242
BCHE butyrylcholinesterase 0.00690023
NEK2 NIMA-related kinase 2 0.00689733
DPYSL3 dihydropyrimidinase-like 3 0.00689175
NID1 nidogen 1 0.00688701
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.00685069
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.00683955
ACTL6A actin-like 6A 0.00683767
ACTC1 actin, alpha, cardiac muscle 1 0.00682373
NKX3-1 NK3 homeobox 1 0.00681032
NDNF neuron-derived neurotrophic factor 0.00679712
HEPH hephaestin 0.00678683
TRIP13 thyroid hormone receptor interactor 13 0.00676702
CCNA2 cyclin A2 0.00674511
PFN1 profilin 1 0.00674042
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.0067265
CD38 CD38 molecule 0.00671176
FBP1 fructose-1,6-bisphosphatase 1 0.00669644
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00666828
ANPEP alanyl (membrane) aminopeptidase 0.00664875
ADAMDEC1 ADAM-like, decysin 1 0.00663648
MAOA monoamine oxidase A 0.00663589
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00663195
NDC80 NDC80 kinetochore complex component 0.00654203
MAP2K6 mitogen-activated protein kinase kinase 6 0.00652181
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00651433
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00650946
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00649313
AMD1 adenosylmethionine decarboxylase 1 0.00647326
BIRC5 baculoviral IAP repeat containing 5 0.00647321
ACSL5 acyl-CoA synthetase long-chain family member 5 0.0064725
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.00641696
MARCKSL1 MARCKS-like 1 0.00639358
NIPSNAP2 nipsnap homolog 2 0.00639286
TMEM38B transmembrane protein 38B 0.00636225
CETN2 centrin, EF-hand protein, 2 0.00635153
RNASEH2A ribonuclease H2, subunit A 0.00635116
PRDX4 peroxiredoxin 4 0.0063504
TPM4 tropomyosin 4 0.00633888
MMP10 matrix metallopeptidase 10 0.00632844
TSPAN8 tetraspanin 8 0.00631961
MICU2 mitochondrial calcium uptake 2 0.00631755
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00630968
PEX2 peroxisomal biogenesis factor 2 0.00628527
RLN1 relaxin 1 0.00627803
ANG angiogenin, ribonuclease, RNase A family, 5 0.00627735
PIMREG PICALM interacting mitotic regulator 0.00627611
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00627583
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.00626458
EFNB3 ephrin-B3 0.0062467
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.00624558
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.00624288
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00618956
TDP2 tyrosyl-DNA phosphodiesterase 2 0.00618742
CCL5 chemokine (C-C motif) ligand 5 0.00618728
CLIC1 chloride intracellular channel 1 0.0061862
CRYBG1 crystallin beta-gamma domain containing 1 0.00618025
UFM1 ubiquitin-fold modifier 1 0.00617811
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00617566
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00616526
HOPX HOP homeobox 0.00613334
MLF1 myeloid leukemia factor 1 0.00612502
IL27RA interleukin 27 receptor, alpha 0.00612287
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.0061178
SLAMF7 SLAM family member 7 0.00610771
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.0061006
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00609248
NAGA N-acetylgalactosaminidase, alpha- 0.00608799
DLK1 delta-like 1 homolog (Drosophila) 0.00606103
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.00604342
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00603872
PLS3 plastin 3 0.00601482
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00599203
RTN1 reticulon 1 0.00598137
SPON1 spondin 1, extracellular matrix protein 0.00597735
PALLD palladin, cytoskeletal associated protein 0.0059714
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00596435
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.00595921
AKAP7 A kinase (PRKA) anchor protein 7 0.00595559
TMPRSS2 transmembrane protease, serine 2 0.00594295
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00594009
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00593284
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00592806
ARG2 arginase 2 0.00591203
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00591063
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00588616
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.00588206
BAG3 BCL2-associated athanogene 3 0.00587629
HMGN4 high mobility group nucleosomal binding domain 4 0.00587175
IQGAP2 IQ motif containing GTPase activating protein 2 0.00587059
GMDS GDP-mannose 4,6-dehydratase 0.00586994
AOC1 amine oxidase, copper containing 1 0.00586897
CRYM crystallin, mu 0.00586753
ESR1 estrogen receptor 1 0.00586364
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00585103
NPR3 natriuretic peptide receptor 3 0.005846
COL6A3 collagen, type VI, alpha 3 0.0058418
S100A10 S100 calcium binding protein A10 0.0058212
PRDX3 peroxiredoxin 3 0.00580888
GPA33 glycoprotein A33 (transmembrane) 0.00579915
OIP5 Opa interacting protein 5 0.00579043
PID1 phosphotyrosine interaction domain containing 1 0.00578473
COPS4 COP9 signalosome subunit 4 0.00578447
MME membrane metallo-endopeptidase 0.00577146
VEGFA vascular endothelial growth factor A 0.00576636
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00575796
IL10RB interleukin 10 receptor, beta 0.00574828
BCL7C B-cell CLL/lymphoma 7C 0.00574706
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.00572807
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00572764
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.00571491
DMBT1 deleted in malignant brain tumors 1 0.00571306
MRPS10 mitochondrial ribosomal protein S10 0.00568877
PIGR polymeric immunoglobulin receptor 0.00565157
HOXB2 homeobox B2 0.00564557
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.0056455
C1QBP complement component 1, q subcomponent binding protein 0.00563733
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.00563611
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.00563089
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.00562557
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00562461
GCHFR GTP cyclohydrolase I feedback regulator 0.00562452
PCSK1 proprotein convertase subtilisin/kexin type 1 0.0056156
DEFA6 defensin, alpha 6, Paneth cell-specific 0.0056108
MTMR11 myotubularin related protein 11 0.00560477
APOO apolipoprotein O 0.00559725
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00559502
RFC3 replication factor C (activator 1) 3, 38kDa 0.00559463
SLC30A9 solute carrier family 30 (zinc transporter), member 9 0.00558932
FOXA1 forkhead box A1 0.00558045
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00557827
MCTP1 multiple C2 domains, transmembrane 1 0.00557195
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.0055598
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00555558
ASF1B anti-silencing function 1B histone chaperone 0.00555026
THAP12 THAP domain containing 12 0.00554933
GREB1 growth regulation by estrogen in breast cancer 1 0.00553957
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00553785
KRT20 keratin 20, type I 0.00553741
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00553447
MRPS18A mitochondrial ribosomal protein S18A 0.00553365
RIMS3 regulating synaptic membrane exocytosis 3 0.00553329
C1QB complement component 1, q subcomponent, B chain 0.00552681
ERLIN2 ER lipid raft associated 2 0.00552583
ACP3 acid phosphatase 3 0.0055258
SPC25 SPC25, NDC80 kinetochore complex component 0.00551897
LMNB1 lamin B1 0.00551428
TFDP1 transcription factor Dp-1 0.00549681
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.00549399
IFITM1 interferon induced transmembrane protein 1 0.00548522
GIMAP4 GTPase, IMAP family member 4 0.00548392
CA11 carbonic anhydrase XI 0.00548375
ADAM28 ADAM metallopeptidase domain 28 0.00548365
TIPRL TOR signaling pathway regulator 0.00547394
TMEM106C transmembrane protein 106C 0.00546548
SIVA1 SIVA1, apoptosis-inducing factor 0.00543254
KRT19 keratin 19, type I 0.00542985
PAK1IP1 PAK1 interacting protein 1 0.00541787

decreased expression

Symbol Name Standardized Value
LTF lactotransferrin -0.0225893
HSPA1A heat shock 70kDa protein 1A -0.0172595
CRISP3 cysteine-rich secretory protein 3 -0.0160486
ANXA3 annexin A3 -0.0143437
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.0136857
ELANE elastase, neutrophil expressed -0.0135763
SLPI secretory leukocyte peptidase inhibitor -0.0131448
GOLGA8A golgin A8 family, member A -0.0131094
DEFA4 defensin, alpha 4, corticostatin -0.0128777
CTSG cathepsin G -0.0121394
KRT7 keratin 7, type II -0.0121302
S100A8 S100 calcium binding protein A8 -0.0119068
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.0118812
MPO myeloperoxidase -0.0117535
S100A12 S100 calcium binding protein A12 -0.011552
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0114621
BPI bactericidal/permeability-increasing protein -0.0113358
RRAGD Ras-related GTP binding D -0.0112417
XIC X chromosome inactivation center -0.0111537
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.0109583
S100A9 S100 calcium binding protein A9 -0.0109375
KRT23 keratin 23, type I -0.0108859
PERP PERP, TP53 apoptosis effector -0.0108049
CRYAB crystallin, alpha B -0.010792
ARG1 arginase 1 -0.0107838
OXA1L oxidase (cytochrome c) assembly 1-like -0.0107735
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0107271
MX1 MX dynamin-like GTPase 1 -0.0107199
PLAAT3 phospholipase A and acyltransferase 3 -0.0106745
TFPI2 tissue factor pathway inhibitor 2 -0.0104679
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0103786
GNAS GNAS complex locus -0.0103531
EGR1 early growth response 1 -0.0101451
CAMP cathelicidin antimicrobial peptide -0.0101131
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0100494
CALML5 calmodulin-like 5 -0.0100132
ALOX5 arachidonate 5-lipoxygenase -0.00998514
MGLL monoglyceride lipase -0.00997645
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00996001
SGCE sarcoglycan, epsilon -0.00964002
RFTN1 raftlin, lipid raft linker 1 -0.00945372
PNN pinin, desmosome associated protein -0.00943686
LYST lysosomal trafficking regulator -0.00942851
CAPN3 calpain 3, (p94) -0.00924835
AZU1 azurocidin 1 -0.00919195
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00908401
PROM1 prominin 1 -0.00897513
PAX5 paired box 5 -0.0089248
G0S2 G0/G1 switch 2 -0.00890545
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00888122
SGK1 serum/glucocorticoid regulated kinase 1 -0.00887825
MAP7 microtubule-associated protein 7 -0.00884116
STK10 serine/threonine kinase 10 -0.00880731
RELN reelin -0.00871779
L1CAM L1 cell adhesion molecule -0.00863529
TACSTD2 tumor-associated calcium signal transducer 2 -0.00853281
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00852597
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00851925
PILRB paired immunoglobin-like type 2 receptor beta -0.00847692
DDIT3 DNA-damage-inducible transcript 3 -0.0084282
KRT14 keratin 14, type I -0.00839991
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00833497
GPX3 glutathione peroxidase 3 -0.00827549
MIR22HG MIR22 host gene -0.00825157
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00818794
COL9A3 collagen, type IX, alpha 3 -0.00818597
SFRP1 secreted frizzled-related protein 1 -0.00817737
CDV3 CDV3 homolog (mouse) -0.00812756
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00810823
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00810795
ATP9A ATPase, class II, type 9A -0.0080978
SCGB2A1 secretoglobin, family 2A, member 1 -0.00807194
DTX4 deltex 4, E3 ubiquitin ligase -0.00803641
MMP8 matrix metallopeptidase 8 -0.00802094
RET ret proto-oncogene -0.0080004
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00795614
BICC1 BicC family RNA binding protein 1 -0.00794044
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00793488
CADM1 cell adhesion molecule 1 -0.00791368
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00789483
H1-0 H1.0 linker histone -0.00785189
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00781954
CTSA cathepsin A -0.00774062
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00765656
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.007644
TRIM29 tripartite motif containing 29 -0.00756478
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00754299
CST6 cystatin E/M -0.00753543
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00749175
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00747195
RNASE3 ribonuclease, RNase A family, 3 -0.00744589
DEFB1 defensin, beta 1 -0.00742174
PEG10 paternally expressed 10 -0.00739993
TSPYL5 TSPY-like 5 -0.00737901
OXTR oxytocin receptor -0.00729695
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00722039
MNDA myeloid cell nuclear differentiation antigen -0.00718303
IRS2 insulin receptor substrate 2 -0.00713724
RGS1 regulator of G-protein signaling 1 -0.00713388
CYB5R2 cytochrome b5 reductase 2 -0.00713373
ANKRD11 ankyrin repeat domain 11 -0.00712173
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00712141
ADIRF adipogenesis regulatory factor -0.00710938
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00709306
MYO6 myosin VI -0.00707085
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00707006
MBD2 methyl-CpG binding domain protein 2 -0.0070533
LIMCH1 LIM and calponin homology domains 1 -0.00703247
FOXC1 forkhead box C1 -0.00699801
MFAP3L microfibrillar-associated protein 3-like -0.00697887
ITSN2 intersectin 2 -0.00696992
ARHGAP29 Rho GTPase activating protein 29 -0.00693731
EREG epiregulin -0.00693029
RPL10 ribosomal protein L10 -0.00692822
IGHMBP2 immunoglobulin mu binding protein 2 -0.00691616
ZIC1 Zic family member 1 -0.00690004
ATF3 activating transcription factor 3 -0.00686806
GOLGA4 golgin A4 -0.00686537
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00685662
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00685256
CLC Charcot-Leyden crystal galectin -0.00682994
POU2AF1 POU class 2 associating factor 1 -0.00681589
CLU clusterin -0.00679817
HMOX1 heme oxygenase 1 -0.00677149
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00676632
NT5E 5'-nucleotidase, ecto (CD73) -0.00676144
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00674524
CCNL2 cyclin L2 -0.00672357
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00666784
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00666582
ADM adrenomedullin -0.00666099
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00665669
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.0066513
GRN granulin -0.0066497
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.00664222
TAC1 tachykinin, precursor 1 -0.0066376
AKAP9 A kinase (PRKA) anchor protein 9 -0.00663423
IL6 interleukin 6 -0.00661865
ELOVL1 ELOVL fatty acid elongase 1 -0.00661124
IFI27 interferon, alpha-inducible protein 27 -0.006594
AMPD3 adenosine monophosphate deaminase 3 -0.0065834
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00656352
PARP6 poly (ADP-ribose) polymerase family, member 6 -0.00652381
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00650708
GAB2 GRB2-associated binding protein 2 -0.00649945
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00648116
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.00647232
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00647151
MEF2A myocyte enhancer factor 2A -0.00646399
FYN FYN proto-oncogene, Src family tyrosine kinase -0.00646121
QPCT glutaminyl-peptide cyclotransferase -0.00643291
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00642243
HBEGF heparin-binding EGF-like growth factor -0.00641887
PDZD2 PDZ domain containing 2 -0.00641446
DOCK9 dedicator of cytokinesis 9 -0.00641277
SCGB1D2 secretoglobin, family 1D, member 2 -0.0064085
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00638666
CLCN7 chloride channel, voltage-sensitive 7 -0.00638417
GUSBP3 glucuronidase, beta pseudogene 3 -0.00637546
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00637411
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00635507
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00635277
SIK1 salt-inducible kinase 1 -0.00635251
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00634869
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00633315
CHD7 chromodomain helicase DNA binding protein 7 -0.00632677
NCF1C neutrophil cytosolic factor 1C pseudogene -0.00632593
KCNK12 potassium channel, two pore domain subfamily K, member 12 -0.00630283
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00628735
CD79B CD79b molecule, immunoglobulin-associated beta -0.00625405
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00625051
TCL1A T-cell leukemia/lymphoma 1A -0.00624418
TMEM131L transmembrane 131 like -0.00623977
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00623904
YPEL5 yippee-like 5 (Drosophila) -0.00623699
PCNA proliferating cell nuclear antigen -0.00621777
BTG2 BTG family, member 2 -0.00621436
PLCB4 phospholipase C, beta 4 -0.00621276
BMP2 bone morphogenetic protein 2 -0.00620982
IL6ST interleukin 6 signal transducer -0.00620972
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00618737
RRAGC Ras-related GTP binding C -0.00618401
SEPTIN8 septin 8 -0.00617918
MGAM maltase-glucoamylase -0.0061702
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00615922
MVP major vault protein -0.006154
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00614786
RGS16 regulator of G-protein signaling 16 -0.00614414
ANO1 anoctamin 1, calcium activated chloride channel -0.00614083
APOLD1 apolipoprotein L domain containing 1 -0.00611045
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00609503
NFASC neurofascin -0.00608536
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.00607689
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00606648
S100A7 S100 calcium binding protein A7 -0.00605304
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.0060513
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00602896
NCOA3 nuclear receptor coactivator 3 -0.00602629
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00598092
NRCAM neuronal cell adhesion molecule -0.00597788
PGLYRP1 peptidoglycan recognition protein 1 -0.00597628
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00597289
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -0.00596752
SCGB2A2 secretoglobin, family 2A, member 2 -0.00596015
MCM2 minichromosome maintenance complex component 2 -0.005955
NNMT nicotinamide N-methyltransferase -0.00594536
USP6NL USP6 N-terminal like -0.00594342
KLF2 Kruppel-like factor 2 -0.0059208
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.00591651
PLA1A phospholipase A1 member A -0.00591533
WIPF1 WAS/WASL interacting protein family, member 1 -0.00591148
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.0058914
CDA cytidine deaminase -0.00587153
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.0058585
PRTN3 proteinase 3 -0.00585614
SLC38A2 solute carrier family 38, member 2 -0.00585049
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.00583613
MAGEA3 melanoma antigen family A3 -0.00582929
PNISR PNN-interacting serine/arginine-rich protein -0.00582589
GPI glucose-6-phosphate isomerase -0.0058112
TASOR2 transcription activation suppressor family member 2 -0.00580564
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.00577869
COCH cochlin -0.00575637
STAG3 stromal antigen 3 -0.00575034
PLPP2 phospholipid phosphatase 2 -0.0057397
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.00572942
RETN resistin -0.00571691
JMJD6 jumonji domain containing 6 -0.00571196
RUNX1 runt-related transcription factor 1 -0.0057015
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00569739
LONP2 lon peptidase 2, peroxisomal -0.00566369
TMEM45A transmembrane protein 45A -0.00565766
SUSD6 sushi domain containing 6 -0.00562626
MBNL2 muscleblind-like splicing regulator 2 -0.00561741
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00560864
ASXL2 additional sex combs like transcriptional regulator 2 -0.00560388
MET MET proto-oncogene, receptor tyrosine kinase -0.00560015
SORBS3 sorbin and SH3 domain containing 3 -0.00559904
LEF1 lymphoid enhancer-binding factor 1 -0.00559895
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00559769
SCD5 stearoyl-CoA desaturase 5 -0.00558724
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.0055852
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.00558388
MT1F metallothionein 1F -0.00558297
GREM1 gremlin 1, DAN family BMP antagonist -0.00557173
TOP2B topoisomerase (DNA) II beta 180kDa -0.00556618
TPCN1 two pore segment channel 1 -0.00556555
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00555105
NPC1 Niemann-Pick disease, type C1 -0.00554304
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00554105