TGIF2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description TGFB-induced factor homeobox 2|The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 60436)
External Link http://www.ncbi.nlm.nih.gov/gene/60436
Similar Terms
Downloads & Tools

Genes

7 interacting proteins for TGIF2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ELAVL1 ELAV like RNA binding protein 1
HDAC1 histone deacetylase 1
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
RBBP8 retinoblastoma binding protein 8
SMAD3 SMAD family member 3
TARBP2 TAR (HIV-1) RNA binding protein 2