TGM2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description transglutaminase 2|Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7052)
External Link https://ncbi.nlm.nih.gov/gene/7052
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Genes

500 genes differentially expressed following the TGM2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CAV1 caveolin 1, caveolae protein, 22kDa 0.0112663
LGALS13 lectin, galactoside-binding, soluble, 13 0.0111212
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.0107309
SRSF1 serine/arginine-rich splicing factor 1 0.0105627
RDX radixin 0.00985354
CA2 carbonic anhydrase II 0.00939917
DAPK1 death-associated protein kinase 1 0.00939278
ODAM odontogenic, ameloblast asssociated 0.00885957
STOM stomatin 0.00879286
ITGA6 integrin, alpha 6 0.00868819
NUSAP1 nucleolar and spindle associated protein 1 0.00852058
ENO2 enolase 2 (gamma, neuronal) 0.00850993
CAV2 caveolin 2 0.00843405
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00841527
EXOC5 exocyst complex component 5 0.00824826
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00819021
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0080882
SCARB2 scavenger receptor class B, member 2 0.00803364
DPYD dihydropyrimidine dehydrogenase 0.00801823
CNN3 calponin 3, acidic 0.00783512
TXNIP thioredoxin interacting protein 0.00770296
CCNA2 cyclin A2 0.00755816
CD14 CD14 molecule 0.00752467
TRAM1 translocation associated membrane protein 1 0.00752144
CLDND1 claudin domain containing 1 0.00746909
KIF14 kinesin family member 14 0.00744903
LYPLA1 lysophospholipase I 0.0074276
MRPL36 mitochondrial ribosomal protein L36 0.00742101
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.00738077
COL15A1 collagen, type XV, alpha 1 0.0072859
MTUS1 microtubule associated tumor suppressor 1 0.00728251
KDM5D lysine (K)-specific demethylase 5D 0.00727993
IL6ST interleukin 6 signal transducer 0.00724121
NELL1 NEL-like 1 (chicken) 0.00717729
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00717233
CANX calnexin 0.00712521
IFI44L interferon-induced protein 44-like 0.00708802
NRN1 neuritin 1 0.00707379
CXCL10 chemokine (C-X-C motif) ligand 10 0.00707181
SCAMP1 secretory carrier membrane protein 1 0.00699722
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00699399
XPO7 exportin 7 0.00698341
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.0069541
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00693315
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00690307
EMP3 epithelial membrane protein 3 0.00687245
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00686694
OSMR oncostatin M receptor 0.00686177
EPAS1 endothelial PAS domain protein 1 0.00684418
MYBPC1 myosin binding protein C, slow type 0.0068438
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.00682012
WSB1 WD repeat and SOCS box containing 1 0.0068179
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00681029
HSPA4L heat shock 70kDa protein 4-like 0.00679867
SPTBN1 spectrin, beta, non-erythrocytic 1 0.00678525
SOX11 SRY (sex determining region Y)-box 11 0.00675888
TMOD3 tropomodulin 3 (ubiquitous) 0.00674239
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.00673625
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00672279
REEP1 receptor accessory protein 1 0.00664341
IPO5 importin 5 0.00663921
LMAN1 lectin, mannose-binding, 1 0.00663594
EHF ets homologous factor 0.00662868
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00655267
CD164 CD164 molecule, sialomucin 0.00654566
MYOT myotilin 0.00653494
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00650257
HHEX hematopoietically expressed homeobox 0.00642233
ALOX5 arachidonate 5-lipoxygenase 0.00640454
FLNA filamin A, alpha 0.00633581
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00630587
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00630561
NCK1 NCK adaptor protein 1 0.00627014
SUB1 SUB1 homolog (S. cerevisiae) 0.00625922
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00625789
MDFIC MyoD family inhibitor domain containing 0.00625754
PRKCB protein kinase C, beta 0.00624264
ADAMTSL3 ADAMTS-like 3 0.00620353
KLHL2 kelch-like family member 2 0.00619855
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00619648
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00616681
DUSP6 dual specificity phosphatase 6 0.00615223
PALMD palmdelphin 0.00612385
KLHL41 kelch-like family member 41 0.00611508
HIPK3 homeodomain interacting protein kinase 3 0.00608357
RC3H2 ring finger and CCCH-type domains 2 0.00605792
F13A1 coagulation factor XIII, A1 polypeptide 0.00603951
TIMP3 TIMP metallopeptidase inhibitor 3 0.00601936
VSIG4 V-set and immunoglobulin domain containing 4 0.00600451
TMC5 transmembrane channel-like 5 0.00598953
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.00597597
ATAD2 ATPase family, AAA domain containing 2 0.00592343
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00592107
GTPBP8 GTP-binding protein 8 (putative) 0.00591213
MPZL2 myelin protein zero-like 2 0.00585071
RYR1 ryanodine receptor 1 (skeletal) 0.00584899
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00584376
CXCL9 chemokine (C-X-C motif) ligand 9 0.00582003
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00581664
GIMAP6 GTPase, IMAP family member 6 0.00576517
UGCG UDP-glucose ceramide glucosyltransferase 0.00575492
ZMYND11 zinc finger, MYND-type containing 11 0.00573945
NNT nicotinamide nucleotide transhydrogenase 0.0057257
ADORA2B adenosine A2b receptor 0.00571299
FCGBP Fc fragment of IgG binding protein 0.00571278
NREP neuronal regeneration related protein 0.00571153
NIBAN1 niban apoptosis regulator 1 0.00568233
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00567165
RAD23B RAD23 homolog B (S. cerevisiae) 0.00566161
SMPX small muscle protein, X-linked 0.00563908
PRDX4 peroxiredoxin 4 0.00563079
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.0056294
UBA6 ubiquitin-like modifier activating enzyme 6 0.00562887
TMEM45A transmembrane protein 45A 0.00561785
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00561183
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00561169
ISL1 ISL LIM homeobox 1 0.00560766
VAMP7 vesicle-associated membrane protein 7 0.00559216
MEX3D mex-3 RNA binding family member D 0.00559066
TAGLN2 transgelin 2 0.00558333
TPM3 tropomyosin 3 0.00556249
CKM creatine kinase, muscle 0.00554323
GLUL glutamate-ammonia ligase 0.00554323
SOD2 superoxide dismutase 2, mitochondrial 0.0055388
USP6NL USP6 N-terminal like 0.00553237
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00551438
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.00549931
WFDC2 WAP four-disulfide core domain 2 0.00549678
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00549609
NT5E 5'-nucleotidase, ecto (CD73) 0.00549583
ISCA1 iron-sulfur cluster assembly 1 0.00548123
ACTB actin, beta 0.00547857
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00546655
ZWILCH zwilch kinetochore protein 0.00545138
ANKRD46 ankyrin repeat domain 46 0.00545071
MOXD1 monooxygenase, DBH-like 1 0.00544207
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00543438
ANXA3 annexin A3 0.00543313
MECOM MDS1 and EVI1 complex locus 0.00542115
STATH statherin 0.00540192
HSF2 heat shock transcription factor 2 0.0053945
RFX7 regulatory factor X, 7 0.00537996
SPIN1 spindlin 1 0.00537879
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 0.00537282
PHF1 PHD finger protein 1 0.00536098
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00535196
CXCL11 chemokine (C-X-C motif) ligand 11 0.00533323
F3 coagulation factor III (thromboplastin, tissue factor) 0.00530832
PRC1 protein regulator of cytokinesis 1 0.00530551
ARHGAP29 Rho GTPase activating protein 29 0.00529799
CCL14 chemokine (C-C motif) ligand 14 0.00528985
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.005264
CSNK1A1 casein kinase 1, alpha 1 0.0052544
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00522647
GOLM1 golgi membrane protein 1 0.00521621
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00520945
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00518295
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00517893
TLR1 toll-like receptor 1 0.00517401
PLN phospholamban 0.00516727
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00516528
MEIS2 Meis homeobox 2 0.0051529
FMO5 flavin containing monooxygenase 5 0.00514298
LEPR leptin receptor 0.00513835
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00513831
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00512945
FGL2 fibrinogen-like 2 0.00510884
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00509742
MCL1 myeloid cell leukemia 1 0.0050973
PCLAF PCNA clamp associated factor 0.00508908
EMP1 epithelial membrane protein 1 0.00508734
DEPDC1 DEP domain containing 1 0.00505824
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.00503624
TYMS thymidylate synthetase 0.00502254
TNNC2 troponin C type 2 (fast) 0.00501969
PRDX2 peroxiredoxin 2 0.00501397
ADCY7 adenylate cyclase 7 0.00501345
DLD dihydrolipoamide dehydrogenase 0.00500928
ACTA1 actin, alpha 1, skeletal muscle 0.00500801
GDE1 glycerophosphodiester phosphodiesterase 1 0.00500128
KCTD9 potassium channel tetramerization domain containing 9 0.00498108
RMI1 RecQ mediated genome instability 1 0.00496962
IQGAP2 IQ motif containing GTPase activating protein 2 0.00496221
EGR3 early growth response 3 0.00496024
RGCC regulator of cell cycle 0.00495777
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00495744
NELL2 NEL-like 2 (chicken) 0.00494855
NFE2L3 nuclear factor, erythroid 2-like 3 0.00494167
FZD6 frizzled class receptor 6 0.00494049
LOX lysyl oxidase 0.00492807
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00492623
ZBTB6 zinc finger and BTB domain containing 6 0.00491137
CLEC7A C-type lectin domain family 7, member A 0.00490933
YBX3 Y box binding protein 3 0.00488029
CLEC2B C-type lectin domain family 2, member B 0.00487485
PBK PDZ binding kinase 0.00486934
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00486827
FHL1 four and a half LIM domains 1 0.00486148
LIMCH1 LIM and calponin homology domains 1 0.00484998
CLIP1 CAP-GLY domain containing linker protein 1 0.00484365
PKM pyruvate kinase, muscle 0.00484184
MYOZ2 myozenin 2 0.00483773
TSPAN8 tetraspanin 8 0.00483631
PCDH8 protocadherin 8 0.00483469
LST1 leukocyte specific transcript 1 0.00483359
PRR4 proline rich 4 (lacrimal) 0.00482857
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00482351
DLG1 discs, large homolog 1 (Drosophila) 0.00481978
SDC4 syndecan 4 0.00481451
MNDA myeloid cell nuclear differentiation antigen 0.00481411
FABP4 fatty acid binding protein 4, adipocyte 0.00481345
CCR2 chemokine (C-C motif) receptor 2 0.00480137
SELENOW selenoprotein W 0.00480095
GSDMB gasdermin B 0.00478315
ADGRL3 adhesion G protein-coupled receptor L3 0.0047814
DPY19L2P2 DPY19L2 pseudogene 2 0.00478104
C4ORF19 chromosome 4 open reading frame 19 0.00476934
S100A8 S100 calcium binding protein A8 0.00476495
SV2C synaptic vesicle glycoprotein 2C 0.00476384
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.0047442
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00474389
AHNAK2 AHNAK nucleoprotein 2 0.00473017
PCSK2 proprotein convertase subtilisin/kexin type 2 0.00472916
CPB2 carboxypeptidase B2 (plasma) 0.00472501
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.00472079
GIMAP4 GTPase, IMAP family member 4 0.00472001
RNF146 ring finger protein 146 0.00471937
ITPRID2 ITPR interacting domain containing 2 0.0047166
PER3 period circadian clock 3 0.00470823
DCTN4 dynactin 4 (p62) 0.004705
CD163 CD163 molecule 0.00470135
C1QA complement component 1, q subcomponent, A chain 0.00469924
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.00469566
PDE4B phosphodiesterase 4B, cAMP-specific 0.00467974
WASL Wiskott-Aldrich syndrome-like 0.00467604
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00466634
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00466247
PNMA2 paraneoplastic Ma antigen 2 0.00465819
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00465407
YOD1 YOD1 deubiquitinase 0.00464876
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00463766
SLBP stem-loop binding protein 0.00462769
CAPN7 calpain 7 0.00462089
CPVL carboxypeptidase, vitellogenic-like 0.00460876
CD1D CD1d molecule 0.00460459
PTPRE protein tyrosine phosphatase, receptor type, E 0.00460391
RCAN2 regulator of calcineurin 2 0.00459529
DSC2 desmocollin 2 0.00458819
SMC2 structural maintenance of chromosomes 2 0.00458693
EIF5 eukaryotic translation initiation factor 5 0.00457761

decreased expression

Symbol Name Standardized Value
MELK maternal embryonic leucine zipper kinase -0.0116575
VCAM1 vascular cell adhesion molecule 1 -0.0103571
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.0101566
PLAAT3 phospholipase A and acyltransferase 3 -0.00968739
CSRP1 cysteine and glycine-rich protein 1 -0.00927317
QPCT glutaminyl-peptide cyclotransferase -0.00887073
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00872511
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00869117
MAP7 microtubule-associated protein 7 -0.00848036
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00833575
SPON1 spondin 1, extracellular matrix protein -0.00817092
SIRT3 sirtuin 3 -0.00814568
PUF60 poly-U binding splicing factor 60KDa -0.00810786
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.00808047
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.00803348
EIF5B eukaryotic translation initiation factor 5B -0.00802584
KRT7 keratin 7, type II -0.00790831
EFHD1 EF-hand domain family, member D1 -0.0079055
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00788581
TBX2 T-box 2 -0.00780609
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00778352
MT1F metallothionein 1F -0.00775769
TBL1X transducin (beta)-like 1X-linked -0.0076741
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00748822
STC2 stanniocalcin 2 -0.00737636
HOXC6 homeobox C6 -0.00735592
IL1R1 interleukin 1 receptor, type I -0.00727343
NNMT nicotinamide N-methyltransferase -0.0071959
MUC2 mucin 2, oligomeric mucus/gel-forming -0.0071897
MT1H metallothionein 1H -0.00714546
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -0.00711182
MCOLN1 mucolipin 1 -0.00707953
SEPP1 selenoprotein P, plasma, 1 -0.00701045
SCGB1D2 secretoglobin, family 1D, member 2 -0.00697121
GLA galactosidase, alpha -0.00692093
NTS neurotensin -0.00691092
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00689994
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00689425
AQP3 aquaporin 3 (Gill blood group) -0.00682974
TXNDC9 thioredoxin domain containing 9 -0.00680235
BGN biglycan -0.00676273
AEBP1 AE binding protein 1 -0.00675247
INHBA inhibin, beta A -0.00671954
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00659017
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00652616
ACAA2 acetyl-CoA acyltransferase 2 -0.0063824
CST7 cystatin F (leukocystatin) -0.00635771
HEPH hephaestin -0.00632796
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -0.00630789
CD8A CD8a molecule -0.00630043
ICA1 islet cell autoantigen 1, 69kDa -0.00629166
NUP85 nucleoporin 85kDa -0.00623263
XIC X chromosome inactivation center -0.00623072
LRP2 low density lipoprotein receptor-related protein 2 -0.00618863
MT1HL1 metallothionein 1H-like 1 -0.0061849
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00617682
GPR137B G protein-coupled receptor 137B -0.00616668
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00616628
KRT18 keratin 18, type I -0.00616617
TALDO1 transaldolase 1 -0.00611142
NOP56 NOP56 ribonucleoprotein -0.00611109
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00604547
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -0.00604436
CHGB chromogranin B -0.00604212
SMYD3 SET and MYND domain containing 3 -0.00597577
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00597352
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -0.0059519
CLDN3 claudin 3 -0.00592227
PCCB propionyl CoA carboxylase, beta polypeptide -0.00590643
MCAM melanoma cell adhesion molecule -0.00590401
PEPD peptidase D -0.00589897
KRT81 keratin 81, type II -0.00589714
WT1 Wilms tumor 1 -0.00589403
KRT19 keratin 19, type I -0.00586649
CLTA clathrin, light chain A -0.00586041
MT1G metallothionein 1G -0.00583653
MAPK13 mitogen-activated protein kinase 13 -0.00583319
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00579795
MICU2 mitochondrial calcium uptake 2 -0.00576694
PXDN peroxidasin -0.00576467
SLC46A3 solute carrier family 46, member 3 -0.00576182
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.00576052
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00574169
ANTKMT adenine nucleotide translocase lysine methyltransferase -0.00573533
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00573403
HIST1H2AC histone cluster 1, H2ac -0.00573167
NADSYN1 NAD synthetase 1 -0.0056994
ISYNA1 inositol-3-phosphate synthase 1 -0.00567964
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -0.0056698
ODC1 ornithine decarboxylase 1 -0.00564061
CLU clusterin -0.00562329
AOC1 amine oxidase, copper containing 1 -0.00562223
MAP1A microtubule-associated protein 1A -0.00561393
COG2 component of oligomeric golgi complex 2 -0.00561122
SKAP2 src kinase associated phosphoprotein 2 -0.00560124
PGLS 6-phosphogluconolactonase -0.0055676
H1-2 H1.2 linker histone, cluster member -0.00555632
SCGB2A2 secretoglobin, family 2A, member 2 -0.00554586
RASL11B RAS-like, family 11, member B -0.0055368
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00553483
ADRA2C adrenoceptor alpha 2C -0.00553127
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00550664
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -0.00549135
ADGRG1 adhesion G protein-coupled receptor G1 -0.0054887
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein -0.00548851
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -0.0054819
IFITM1 interferon induced transmembrane protein 1 -0.00548127
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00548046
EDNRB endothelin receptor type B -0.00547625
TTC39A tetratricopeptide repeat domain 39A -0.00541797
PRSS3 protease, serine, 3 -0.00541233
MMP19 matrix metallopeptidase 19 -0.00537684
HIST1H2BD histone cluster 1, H2bd -0.00535949
OSBPL10 oxysterol binding protein-like 10 -0.00535872
NIT2 nitrilase family, member 2 -0.0053545
TCTA T-cell leukemia translocation altered -0.00534408
COL16A1 collagen, type XVI, alpha 1 -0.00533528
MT1X metallothionein 1X -0.00532896
CTSW cathepsin W -0.0053087
SPATA20 spermatogenesis associated 20 -0.00529027
ATP10A ATPase, class V, type 10A -0.0052765
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00527179
MAL mal, T-cell differentiation protein -0.00527151
ELOVL1 ELOVL fatty acid elongase 1 -0.00526051
THBS2 thrombospondin 2 -0.00525973
USH1C Usher syndrome 1C (autosomal recessive, severe) -0.00524736
MRPL28 mitochondrial ribosomal protein L28 -0.00524542
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00524493
CTSA cathepsin A -0.00524436
EHD1 EH-domain containing 1 -0.00522124
CLTB clathrin, light chain B -0.00521937
SELENBP1 selenium binding protein 1 -0.00521182
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00519529
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.0051872
RCAN1 regulator of calcineurin 1 -0.00517968
CLEC11A C-type lectin domain family 11, member A -0.0051749
ZNF544 zinc finger protein 544 -0.00517149
SHLD2 shieldin complex subunit 2 -0.00516884
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00516295
FMO1 flavin containing monooxygenase 1 -0.00514411
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.00513831
GUCY2C guanylate cyclase 2C -0.00512712
LXN latexin -0.00512338
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00510112
COLEC11 collectin sub-family member 11 -0.00508824
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00508035
FIBP fibroblast growth factor (acidic) intracellular binding protein -0.0050546
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00505025
ACAA1 acetyl-CoA acyltransferase 1 -0.00504603
TPP1 tripeptidyl peptidase I -0.00504185
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00504031
E2F2 E2F transcription factor 2 -0.00500138
LAMP1 lysosomal-associated membrane protein 1 -0.00497629
COL18A1 collagen, type XVIII, alpha 1 -0.00494558
ENG endoglin -0.00494426
ADD3 adducin 3 (gamma) -0.00494416
BAMBI BMP and activin membrane-bound inhibitor -0.00492993
SLC16A6 solute carrier family 16, member 6 -0.0049185
PI3 peptidase inhibitor 3, skin-derived -0.00491814
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.00491119
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00490581
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00490487
UFM1 ubiquitin-fold modifier 1 -0.00489857
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00489723
RSAD1 radical S-adenosyl methionine domain containing 1 -0.00489082
SGPL1 sphingosine-1-phosphate lyase 1 -0.00488957
DLK1 delta-like 1 homolog (Drosophila) -0.00488503
XYLT1 xylosyltransferase I -0.00487572
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.00486755
GLYAT glycine-N-acyltransferase -0.00486229
PEBP1 phosphatidylethanolamine binding protein 1 -0.00484314
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -0.00483261
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma -0.00483182
SLC44A4 solute carrier family 44, member 4 -0.00483009
NEU1 sialidase 1 (lysosomal sialidase) -0.00482823
RGS5 regulator of G-protein signaling 5 -0.00482656
STYXL1 serine/threonine/tyrosine interacting-like 1 -0.00482283
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00481861
IL17RB interleukin 17 receptor B -0.00481104
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00480876
KYNU kynureninase -0.0047961
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00479366
TRIB3 tribbles pseudokinase 3 -0.00479131
PALM paralemmin -0.00475729
PKP3 plakophilin 3 -0.0047524
PLAT plasminogen activator, tissue -0.0047493
TM4SF1 transmembrane 4 L six family member 1 -0.00474539
NRCAM neuronal cell adhesion molecule -0.00473215
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00471194
TP53I3 tumor protein p53 inducible protein 3 -0.00470062
CDR2L cerebellar degeneration-related protein 2-like -0.00469447
SH2D2A SH2 domain containing 2A -0.00468495
FAHD2A fumarylacetoacetate hydrolase domain containing 2A -0.00468125
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00467863
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -0.00466371
TBX3 T-box 3 -0.00466182
TARP TCR gamma alternate reading frame protein -0.00466113
CTBP2 C-terminal binding protein 2 -0.00465396
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00465202
UBAP2 ubiquitin associated protein 2 -0.00465011
HSPA8 heat shock 70kDa protein 8 -0.00464923
FOXG1 forkhead box G1 -0.00464897
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -0.00464342
ABHD11 abhydrolase domain containing 11 -0.00463938
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0046362
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) -0.00462797
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00460771
QDPR quinoid dihydropteridine reductase -0.00460408
LMCD1 LIM and cysteine-rich domains 1 -0.00458443
KRT20 keratin 20, type I -0.00458232
BASP1 brain abundant, membrane attached signal protein 1 -0.00457149
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00456933
ANO10 anoctamin 10 -0.00456339
SUOX sulfite oxidase -0.00455478
PNMA8A PNMA family member 8A -0.0045497
ARMCX6 armadillo repeat containing, X-linked 6 -0.00453488
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00453149
CPB1 carboxypeptidase B1 (tissue) -0.00453072
CRIP1 cysteine-rich protein 1 (intestinal) -0.00451974
EPS8L1 EPS8-like 1 -0.00451002
CRABP1 cellular retinoic acid binding protein 1 -0.00450688
BOP1 block of proliferation 1 -0.00450411
BICC1 BicC family RNA binding protein 1 -0.00450172
IFT88 intraflagellar transport 88 -0.00450009
GUSB glucuronidase, beta -0.00450004
POR P450 (cytochrome) oxidoreductase -0.00449502
DHCR7 7-dehydrocholesterol reductase -0.00449436
QPRT quinolinate phosphoribosyltransferase -0.00447322
MTIF2 mitochondrial translational initiation factor 2 -0.00447257
TFPI2 tissue factor pathway inhibitor 2 -0.00446861
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00445219
SDF2L1 stromal cell-derived factor 2-like 1 -0.00443919
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -0.00443819
MRPL58 mitochondrial ribosomal protein L58 -0.00443601
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -0.00443337
NAV3 neuron navigator 3 -0.00441925
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.00441857
MFSD1 major facilitator superfamily domain containing 1 -0.00441856
CUTA cutA divalent cation tolerance homolog (E. coli) -0.00440574
RAI2 retinoic acid induced 2 -0.00440053
P3H2 prolyl 3-hydroxylase 2 -0.0043846
AATF apoptosis antagonizing transcription factor -0.00437623
ADIRF adipogenesis regulatory factor -0.00436887
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -0.00436714
AKAP8 A kinase (PRKA) anchor protein 8 -0.00436434
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00434675
LAMC3 laminin, gamma 3 -0.00433427
MT2A metallothionein 2A -0.00432783
PDGFD platelet derived growth factor D -0.00432552
LEFTY1 left-right determination factor 1 -0.00432213