| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | tyrosine hydroxylase|The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7054) |
| External Link | https://ncbi.nlm.nih.gov/gene/7054 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TH gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0140518 |
| BMP4 | bone morphogenetic protein 4 | 0.012624 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0124958 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0113799 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0111445 |
| TMSB15A | thymosin beta 15a | 0.0108984 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.010534 |
| FZD6 | frizzled class receptor 6 | 0.0103228 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0101728 |
| STXBP2 | syntaxin binding protein 2 | 0.0101086 |
| RPA3 | replication protein A3, 14kDa | 0.00987868 |
| LOX | lysyl oxidase | 0.00952598 |
| NMU | neuromedin U | 0.00925588 |
| PRDX2 | peroxiredoxin 2 | 0.00923707 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00920597 |
| RGCC | regulator of cell cycle | 0.00893526 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00872385 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00869983 |
| LXN | latexin | 0.00860919 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00857228 |
| CLU | clusterin | 0.008567 |
| CHN1 | chimerin 1 | 0.00851625 |
| FADS1 | fatty acid desaturase 1 | 0.00838559 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00823448 |
| CD52 | CD52 molecule | 0.00796564 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00791035 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00780177 |
| RGS5 | regulator of G-protein signaling 5 | 0.00775471 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00770914 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00759482 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00751623 |
| NNMT | nicotinamide N-methyltransferase | 0.00751267 |
| FRZB | frizzled-related protein | 0.00742744 |
| ANXA1 | annexin A1 | 0.00731763 |
| CA2 | carbonic anhydrase II | 0.00729456 |
| COMMD8 | COMM domain containing 8 | 0.00723045 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0072234 |
| DCK | deoxycytidine kinase | 0.00720292 |
| STMN2 | stathmin 2 | 0.00718122 |
| TMEM47 | transmembrane protein 47 | 0.00713162 |
| ADIRF | adipogenesis regulatory factor | 0.007118 |
| MPO | myeloperoxidase | 0.00711159 |
| FHL1 | four and a half LIM domains 1 | 0.00710632 |
| TSPAN7 | tetraspanin 7 | 0.00710625 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00709782 |
| IFT57 | intraflagellar transport 57 | 0.00708001 |
| FST | follistatin | 0.00707089 |
| MAOA | monoamine oxidase A | 0.00706611 |
| CSTA | cystatin A (stefin A) | 0.0070534 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00702188 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00701588 |
| ZNF423 | zinc finger protein 423 | 0.00701553 |
| BEX1 | brain expressed, X-linked 1 | 0.00699039 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00697171 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00691519 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00691159 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00685503 |
| TMEM14B | transmembrane protein 14B | 0.00685401 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00683966 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00683519 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00681425 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00680742 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00676468 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00670773 |
| H1-2 | H1.2 linker histone, cluster member | 0.0067066 |
| EPHA4 | EPH receptor A4 | 0.00670222 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00669972 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00669201 |
| PDCD10 | programmed cell death 10 | 0.00666586 |
| CEP70 | centrosomal protein 70kDa | 0.00665963 |
| SRGN | serglycin | 0.0066564 |
| HHEX | hematopoietically expressed homeobox | 0.0066422 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00663272 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00660466 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00658519 |
| METTL7A | methyltransferase like 7A | 0.00654121 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00652918 |
| ADCY2 | adenylate cyclase 2 (brain) | 0.00651773 |
| CYBRD1 | cytochrome b reductase 1 | 0.00649617 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00648644 |
| FASN | fatty acid synthase | 0.00647673 |
| CTSG | cathepsin G | 0.00647295 |
| ORC4 | origin recognition complex, subunit 4 | 0.00646126 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00638154 |
| FSTL1 | follistatin-like 1 | 0.00637176 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00636416 |
| TMEM126B | transmembrane protein 126B | 0.00633636 |
| CA4 | carbonic anhydrase IV | 0.00628575 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.00626259 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | 0.00624997 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00624557 |
| METTL5 | methyltransferase like 5 | 0.0061929 |
| FOLR1 | folate receptor 1 (adult) | 0.0061856 |
| FASTKD3 | FAST kinase domains 3 | 0.00617568 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.00617169 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00617075 |
| BEX4 | brain expressed, X-linked 4 | 0.00616707 |
| FOXF1 | forkhead box F1 | 0.0061246 |
| HAT1 | histone acetyltransferase 1 | 0.00606304 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.00606109 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00602883 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00602691 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00602312 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00601345 |
| FBXO11 | F-box protein 11 | 0.00600196 |
| PFDN5 | prefoldin subunit 5 | 0.00599323 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00599087 |
| EVI2A | ecotropic viral integration site 2A | 0.00594974 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00594708 |
| EZR | ezrin | 0.00590709 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00589938 |
| GOLT1B | golgi transport 1B | 0.00588471 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00585771 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00584132 |
| ZNF331 | zinc finger protein 331 | 0.00581362 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.0057858 |
| WASF1 | WAS protein family, member 1 | 0.00577907 |
| MID1IP1 | MID1 interacting protein 1 | 0.0057491 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00573756 |
| CD302 | CD302 molecule | 0.00571381 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.00568548 |
| ELANE | elastase, neutrophil expressed | 0.00567967 |
| TPRKB | TP53RK binding protein | 0.00565651 |
| LY96 | lymphocyte antigen 96 | 0.00564305 |
| SC5D | sterol-C5-desaturase | 0.00562429 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00561196 |
| CD83 | CD83 molecule | 0.00559906 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00558196 |
| MED28 | mediator complex subunit 28 | 0.00558072 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00556428 |
| CLC | Charcot-Leyden crystal galectin | 0.00555399 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00554957 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00553207 |
| CNN3 | calponin 3, acidic | 0.00552938 |
| RGS10 | regulator of G-protein signaling 10 | 0.00551549 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00551502 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00551251 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00551104 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00548906 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.0054881 |
| VRK1 | vaccinia related kinase 1 | 0.00548203 |
| OIP5 | Opa interacting protein 5 | 0.0054816 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00547324 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00546589 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.00546242 |
| LRRC17 | leucine rich repeat containing 17 | 0.00545396 |
| CCNG1 | cyclin G1 | 0.00544623 |
| ISL1 | ISL LIM homeobox 1 | 0.00544517 |
| PRDX3 | peroxiredoxin 3 | 0.00542976 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.00542235 |
| MDFIC | MyoD family inhibitor domain containing | 0.00541852 |
| PAQR3 | progestin and adipoQ receptor family member III | 0.00541638 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00539527 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00537814 |
| EAPP | E2F-associated phosphoprotein | 0.00537562 |
| CD99 | CD99 molecule | 0.00537271 |
| CHKB | choline kinase beta | 0.00535416 |
| APIP | APAF1 interacting protein | 0.0053407 |
| MGAM | maltase-glucoamylase | 0.00532335 |
| IFT52 | intraflagellar transport 52 | 0.00532106 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.00531279 |
| CLCA4 | chloride channel accessory 4 | 0.00531023 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00531021 |
| PFDN4 | prefoldin subunit 4 | 0.00530508 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00528313 |
| CAV2 | caveolin 2 | 0.0052825 |
| GPX3 | glutathione peroxidase 3 | 0.00528004 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0052684 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00526295 |
| HTRA1 | HtrA serine peptidase 1 | 0.00525032 |
| WBP5 | WW domain binding protein 5 | 0.00524921 |
| LEPR | leptin receptor | 0.0052463 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.0052461 |
| CEL | carboxyl ester lipase | 0.00524335 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00524089 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00523481 |
| FBXO5 | F-box protein 5 | 0.00522606 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00522414 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00522195 |
| HOXD1 | homeobox D1 | 0.00520885 |
| C1ORF174 | chromosome 1 open reading frame 174 | 0.00520276 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00519903 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 0.00519783 |
| STOM | stomatin | 0.00518893 |
| MAGEH1 | melanoma antigen family H1 | 0.00518675 |
| APOC1 | apolipoprotein C-I | 0.00518197 |
| TOX | thymocyte selection-associated high mobility group box | 0.0051816 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00518022 |
| PLN | phospholamban | 0.00517021 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00516091 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00515532 |
| ANGPT1 | angiopoietin 1 | 0.00515371 |
| ESM1 | endothelial cell-specific molecule 1 | 0.00515305 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.0051483 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.00513619 |
| TMEM50B | transmembrane protein 50B | 0.00513147 |
| ATF1 | activating transcription factor 1 | 0.0051161 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00511145 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00510835 |
| MOAP1 | modulator of apoptosis 1 | 0.00510661 |
| FOXF2 | forkhead box F2 | 0.00509396 |
| KRT19 | keratin 19, type I | 0.00508811 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00507566 |
| BTG3 | BTG family, member 3 | 0.00506048 |
| CCDC176 | coiled-coil domain containing 176 | 0.00505845 |
| BCAS2 | breast carcinoma amplified sequence 2 | 0.00505213 |
| ASPH | aspartate beta-hydroxylase | 0.00505161 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00504465 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00503398 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00502747 |
| MRPL49 | mitochondrial ribosomal protein L49 | 0.0050243 |
| EAF2 | ELL associated factor 2 | 0.00502309 |
| CYB5R4 | cytochrome b5 reductase 4 | 0.00502229 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00501877 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00501849 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 0.00501744 |
| MREG | melanoregulin | 0.00500782 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00499343 |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.00498858 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00498682 |
| TRAPPC2L | trafficking protein particle complex 2-like | 0.00498623 |
| CFD | complement factor D (adipsin) | 0.00497995 |
| COPS4 | COP9 signalosome subunit 4 | 0.00497667 |
| SEPTIN10 | septin 10 | 0.00497514 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00496867 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.00496319 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00496052 |
| CD200 | CD200 molecule | 0.00495201 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00495135 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.00495005 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00493172 |
| PCLAF | PCNA clamp associated factor | 0.00492375 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00492343 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00491969 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.00490941 |
| BMX | BMX non-receptor tyrosine kinase | 0.00490821 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00490415 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00489846 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00489841 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00485839 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00485106 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00484461 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0048319 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00482892 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00482888 |
| FLT1 | fms-related tyrosine kinase 1 | 0.00482508 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00482035 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00481711 |
| CDCA4 | cell division cycle associated 4 | 0.00481446 |
| CCNE2 | cyclin E2 | 0.00481322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFF1 | trefoil factor 1 | -0.0166345 |
| CD320 | CD320 molecule | -0.0125036 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0121085 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0111219 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0106345 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00975107 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00962198 |
| KLF6 | Kruppel-like factor 6 | -0.00957055 |
| XIC | X chromosome inactivation center | -0.00956521 |
| COPS7A | COP9 signalosome subunit 7A | -0.00950992 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00942863 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00939179 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00932946 |
| LAMC2 | laminin, gamma 2 | -0.00925166 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00920886 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00911706 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00908764 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00908621 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00908585 |
| FMOD | fibromodulin | -0.00906852 |
| TSPAN8 | tetraspanin 8 | -0.0089424 |
| MX1 | MX dynamin-like GTPase 1 | -0.00877047 |
| EGR2 | early growth response 2 | -0.00848318 |
| IL32 | interleukin 32 | -0.00842951 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00842165 |
| XPO7 | exportin 7 | -0.00833439 |
| COL9A3 | collagen, type IX, alpha 3 | -0.0083259 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00824594 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00819606 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00815117 |
| RRAGA | Ras-related GTP binding A | -0.00813973 |
| KRT7 | keratin 7, type II | -0.00799252 |
| KRT14 | keratin 14, type I | -0.00786821 |
| WT1 | Wilms tumor 1 | -0.0078402 |
| VEGFA | vascular endothelial growth factor A | -0.00768067 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00763775 |
| S100A11 | S100 calcium binding protein A11 | -0.00753783 |
| KYNU | kynureninase | -0.00752725 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00750216 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00745175 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.0073498 |
| CLTB | clathrin, light chain B | -0.00733408 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00727047 |
| GPX2 | glutathione peroxidase 2 | -0.00724456 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00722806 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00720466 |
| NOP2 | NOP2 nucleolar protein | -0.00718887 |
| PRF1 | perforin 1 (pore forming protein) | -0.00716412 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00714725 |
| IRF7 | interferon regulatory factor 7 | -0.00707016 |
| TCAF1 | TRPM8 channel-associated factor 1 | -0.00702364 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00699438 |
| MAP7 | microtubule-associated protein 7 | -0.00699321 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00695607 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00691616 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00691149 |
| SMAD3 | SMAD family member 3 | -0.00690257 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00689095 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00688032 |
| CTPS1 | CTP synthase 1 | -0.00686957 |
| ALB | albumin | -0.00682519 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | -0.00682217 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00678447 |
| MLXIP | MLX interacting protein | -0.00676945 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00667404 |
| IL2RG | interleukin 2 receptor, gamma | -0.00663193 |
| SIRT3 | sirtuin 3 | -0.00658914 |
| RBM34 | RNA binding motif protein 34 | -0.00655852 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00652707 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00652147 |
| MMP7 | matrix metallopeptidase 7 | -0.00649495 |
| RHOC | ras homolog family member C | -0.00648848 |
| MIA | melanoma inhibitory activity | -0.00642932 |
| IL1RN | interleukin 1 receptor antagonist | -0.00641688 |
| IPO13 | importin 13 | -0.00639957 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00634579 |
| EGR1 | early growth response 1 | -0.00632762 |
| APOD | apolipoprotein D | -0.00630606 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00628275 |
| JMJD6 | jumonji domain containing 6 | -0.00626901 |
| KRT17 | keratin 17, type I | -0.00620871 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00619741 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00619476 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00618536 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00614651 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0061434 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00610457 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00607818 |
| EPHB3 | EPH receptor B3 | -0.00605591 |
| MVP | major vault protein | -0.0060534 |
| RNASET2 | ribonuclease T2 | -0.00603508 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0060261 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00602302 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0060056 |
| LAMB3 | laminin, beta 3 | -0.0059958 |
| ECM1 | extracellular matrix protein 1 | -0.00598982 |
| IFI44L | interferon-induced protein 44-like | -0.00596215 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00594039 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00593835 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.00593379 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00591737 |
| VPREB1 | pre-B lymphocyte 1 | -0.00588079 |
| NKG7 | natural killer cell granule protein 7 | -0.00586986 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00584557 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00583246 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00582233 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00581781 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00580673 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00576472 |
| SPATA20 | spermatogenesis associated 20 | -0.00575517 |
| PCDH9 | protocadherin 9 | -0.00575283 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00574137 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00573335 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0057326 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00568199 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00567461 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0056456 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00563371 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00558597 |
| EMILIN1 | elastin microfibril interfacer 1 | -0.00558161 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00555973 |
| TEAD4 | TEA domain family member 4 | -0.00554346 |
| CD81 | CD81 molecule | -0.00551171 |
| MMP1 | matrix metallopeptidase 1 | -0.0055074 |
| NOTCH2NL | notch 2 N-terminal like | -0.00547345 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00544464 |
| CTSE | cathepsin E | -0.00544284 |
| FAM102A | family with sequence similarity 102, member A | -0.00542438 |
| CD8A | CD8a molecule | -0.00540721 |
| MYO1E | myosin IE | -0.0054062 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00539661 |
| CDC25B | cell division cycle 25B | -0.00538645 |
| PYGB | phosphorylase, glycogen; brain | -0.00537638 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00535356 |
| ACTN4 | actinin, alpha 4 | -0.00529973 |
| AGR2 | anterior gradient 2 | -0.00529058 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00525965 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00525506 |
| GNLY | granulysin | -0.00523768 |
| FAM53B | family with sequence similarity 53, member B | -0.00521382 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00519363 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | -0.00518852 |
| IL2RB | interleukin 2 receptor, beta | -0.00518692 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00518481 |
| MUC13 | mucin 13, cell surface associated | -0.00518216 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00517072 |
| DIO1 | deiodinase, iodothyronine, type I | -0.0051703 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00516111 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00514299 |
| YBX3 | Y box binding protein 3 | -0.00513986 |
| LMNA | lamin A/C | -0.00513008 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00511941 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00511274 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00510955 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00510923 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00510913 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00510432 |
| ZYX | zyxin | -0.00510371 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.00509761 |
| IRF9 | interferon regulatory factor 9 | -0.00509389 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0050825 |
| LAD1 | ladinin 1 | -0.0050815 |
| TRIB2 | tribbles pseudokinase 2 | -0.00507098 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00506652 |
| ITK | IL2-inducible T-cell kinase | -0.00502551 |
| E2F2 | E2F transcription factor 2 | -0.0050134 |
| HELZ | helicase with zinc finger | -0.00501084 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.00499258 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00499224 |
| LAMB1 | laminin, beta 1 | -0.00499091 |
| CLSTN3 | calsyntenin 3 | -0.00498899 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00498869 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00498849 |
| NCOR2 | nuclear receptor corepressor 2 | -0.00498816 |
| LIPG | lipase, endothelial | -0.00498754 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | -0.0049803 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00497778 |
| KIF13B | kinesin family member 13B | -0.00497659 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00497588 |
| SYNGR3 | synaptogyrin 3 | -0.00497379 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00496982 |
| TESC | tescalcin | -0.00496045 |
| MARCKSL1 | MARCKS-like 1 | -0.00494346 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -0.00493775 |
| TFF2 | trefoil factor 2 | -0.00493098 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.00492125 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.00491304 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00491262 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00491056 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00490916 |
| PRKCA | protein kinase C, alpha | -0.00489896 |
| ATF5 | activating transcription factor 5 | -0.00489862 |
| DUSP4 | dual specificity phosphatase 4 | -0.00489522 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00489367 |
| MMP12 | matrix metallopeptidase 12 | -0.0048677 |
| CCND2 | cyclin D2 | -0.00484998 |
| OPN3 | opsin 3 | -0.0048435 |
| DPP6 | dipeptidyl-peptidase 6 | -0.00484275 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00483686 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00483085 |
| PSCA | prostate stem cell antigen | -0.00482335 |
| C1RL | complement component 1, r subcomponent-like | -0.00480969 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00478101 |
| OGN | osteoglycin | -0.00477367 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -0.00475231 |
| FCGBP | Fc fragment of IgG binding protein | -0.00474695 |
| ENO1 | enolase 1, (alpha) | -0.00474493 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | -0.00474432 |
| PUM3 | pumilio RNA binding family member 3 | -0.00474401 |
| DSP | desmoplakin | -0.00473955 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.00473615 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00473265 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | -0.00472276 |
| PLCB4 | phospholipase C, beta 4 | -0.00472051 |
| BMERB1 | bMERB domain containing 1 | -0.00471851 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0046844 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00468269 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00468154 |
| RET | ret proto-oncogene | -0.00468058 |
| UPP1 | uridine phosphorylase 1 | -0.00467652 |
| TAOK3 | TAO kinase 3 | -0.00466346 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00466311 |
| AUTS2 | autism susceptibility candidate 2 | -0.00466122 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.00466001 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00465841 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00465653 |
| ANXA6 | annexin A6 | -0.00464563 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.00464481 |
| HIP1R | huntingtin interacting protein 1 related | -0.00464385 |
| COG7 | component of oligomeric golgi complex 7 | -0.0046206 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00461203 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00460826 |
| CADM1 | cell adhesion molecule 1 | -0.00460637 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00460216 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00459729 |
| CALB1 | calbindin 1, 28kDa | -0.00459533 |
| CTSW | cathepsin W | -0.00459175 |
| NCALD | neurocalcin delta | -0.00458664 |
| CD247 | CD247 molecule | -0.00458411 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.00457238 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 | -0.00457161 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00456802 |
| GPR171 | G protein-coupled receptor 171 | -0.00456182 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | -0.0045512 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00454924 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00454789 |
| FUS | FUS RNA binding protein | -0.00454569 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00454415 |
| PSPC1 | paraspeckle component 1 | -0.00454032 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | -0.00453947 |
