TH Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description tyrosine hydroxylase|The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7054)
External Link http://www.ncbi.nlm.nih.gov/gene/7054
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23 interacting proteins for TH from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDK11B cyclin-dependent kinase 11B
CSNK2A1 casein kinase 2, alpha 1 polypeptide
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TYSND1 trypsin domain containing 1
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta