THAP11 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description THAP domain containing 11|The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 57215)
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Genes

356 genes differentially expressed following the THAP11 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
COL20A1 collagen, type XX, alpha 1 2.87073
GFRA4 GDNF family receptor alpha 4 2.87073
PON1 paraoxonase 1 2.87073
PCDHB6 protocadherin beta 6 2.87073
FOXA2 forkhead box A2 2.87073
TNNI1 troponin I type 1 (skeletal, slow) 2.87073
PCDHGB3 protocadherin gamma subfamily B, 3 2.87073
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 2.87073
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.87073
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.87073
CSTL1 cystatin-like 1 2.87073
PAX5 paired box 5 2.87073
PRSS41 protease, serine, 41 2.87073
PRICKLE1 prickle homolog 1 (Drosophila) 2.87073
CD274 CD274 molecule 2.87073
AGTR1 angiotensin II receptor, type 1 2.87073
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.87073
FGF20 fibroblast growth factor 20 2.87073
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.87073
LIPN lipase, family member N 2.87073
IZUMO3 IZUMO family member 3 2.87073
XAF1 XIAP associated factor 1 2.87073
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.87073
GNLY granulysin 2.87073
SLC16A11 solute carrier family 16, member 11 2.87073
COL16A1 collagen, type XVI, alpha 1 2.87073
HCRTR2 hypocretin (orexin) receptor 2 2.87073
LRRC66 leucine rich repeat containing 66 2.87073
MUC20 mucin 20, cell surface associated 2.87073
TREML2 triggering receptor expressed on myeloid cells-like 2 2.87073
HYPK huntingtin interacting protein K 2.87073
LIMD1 LIM domains containing 1 2.87073
TAS2R19 taste receptor, type 2, member 19 2.87073
TRPC5OS TRPC5 opposite strand 2.87073
SP6 Sp6 transcription factor 2.87073
LOC105378220 macrophage receptor MARCO-like 2.87073
HIC1 hypermethylated in cancer 1 2.87073
SPAG8 sperm associated antigen 8 2.87073
TMEM121 transmembrane protein 121 2.87073
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.87073
CA6 carbonic anhydrase VI 2.87073
RFPL2 ret finger protein-like 2 2.87073
RFPL3 ret finger protein-like 3 2.87073
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.87073
LY6G6F lymphocyte antigen 6 complex, locus G6F 2.87073
RGPD3 RANBP2-like and GRIP domain containing 3 2.87073
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.87073
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.87073
ACKR5 atypical chemokine receptor 5 2.87073
CBY1 chibby homolog 1 (Drosophila) 2.87073
DLL4 delta-like 4 (Drosophila) 2.87073
PMCH pro-melanin-concentrating hormone 2.87073
LITAFD LITAF domain containing 2.87073
STMN1 stathmin 1 2.87073
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 2.87073
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 2.87073
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.87073
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.87073
LTK leukocyte receptor tyrosine kinase 2.87073
MOV10L1 Mov10 RISC complex RNA helicase like 1 2.87073
WNT9B wingless-type MMTV integration site family, member 9B 2.87073
LRRC73 leucine rich repeat containing 73 2.87073
TIMD4 T-cell immunoglobulin and mucin domain containing 4 2.87073
IL1RN interleukin 1 receptor antagonist 2.87073
ALX4 ALX homeobox 4 2.87073
AVPR1B arginine vasopressin receptor 1B 2.87073
DEFB109B defensin beta 109B 2.87073
LOC124903372 uncharacterized LOC124903372 2.87073
EZHIP EZH inhibitory protein 2.87073
PEAK3 PEAK family member 3 2.87073
STPG3 sperm-tail PG-rich repeat containing 3 2.87073
H2AC1 H2A clustered histone 1 2.87073
WDR97 WD repeat domain 97 2.87073
LORICRIN loricrin cornified envelope precursor protein 2.87073
EPOP elongin BC and polycomb repressive complex 2 associated protein 2.87073
PSPN persephin 2.87073
MCHR2 melanin-concentrating hormone receptor 2 2.87073
PGA5 pepsinogen 5, group I (pepsinogen A) 2.87073
CNTFR ciliary neurotrophic factor receptor 2.87073
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.87073
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 2.87073
LGALS7B lectin, galactoside-binding, soluble, 7B 2.87073
TUBA3E tubulin, alpha 3e 2.87073
FAM153A family with sequence similarity 153, member A 2.87073
SCARA5 scavenger receptor class A, member 5 2.87073
ZNF582 zinc finger protein 582 2.87073
GJA5 gap junction protein, alpha 5, 40kDa 2.87073
TMPRSS11D transmembrane protease, serine 11D 2.87073
TMPRSS11A transmembrane protease, serine 11A 2.87073
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.87073
FNTB farnesyltransferase, CAAX box, beta 2.87073
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.87073
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.87073
CCR8 chemokine (C-C motif) receptor 8 2.87073
CREB3L3 cAMP responsive element binding protein 3-like 3 2.87073
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.87073
SCN7A sodium channel, voltage gated, type VII alpha subunit 2.87073
SLAMF6 SLAM family member 6 2.87073
RNF113B ring finger protein 113B 2.87073
TFEC transcription factor EC 2.87073
OR2A12 olfactory receptor, family 2, subfamily A, member 12 2.87073
SCRT1 scratch family zinc finger 1 2.87073
TMEM235 transmembrane protein 235 2.87073
CST11 cystatin 11 2.87073
GPBAR1 G protein-coupled bile acid receptor 1 2.87073
NKX6-3 NK6 homeobox 3 2.87073
TMEM154 transmembrane protein 154 2.87073
TCF21 transcription factor 21 2.87073
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.87073
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.87073
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.87073
PCDHGB1 protocadherin gamma subfamily B, 1 2.87073
CCDC154 coiled-coil domain containing 154 2.87073
RSAD2 radical S-adenosyl methionine domain containing 2 2.87073
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.87073
NTSR1 neurotensin receptor 1 (high affinity) 2.87073
MMP3 matrix metallopeptidase 3 2.87073
FADS6 fatty acid desaturase 6 2.87073
SLC7A4 solute carrier family 7, member 4 2.87073
FAIM2 Fas apoptotic inhibitory molecule 2 2.87073
ZNF214 zinc finger protein 214 2.87073
C5AR2 complement component 5a receptor 2 2.87073
ACKR2 atypical chemokine receptor 2 2.87073
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.87073
DBX2 developing brain homeobox 2 2.87073
LRRC25 leucine rich repeat containing 25 2.87073
FATE1 fetal and adult testis expressed 1 2.87073
RGS8 regulator of G-protein signaling 8 2.87073
MAB21L2 mab-21-like 2 (C. elegans) 2.87073
DND1 DND microRNA-mediated repression inhibitor 1 2.87073
DMRT1 doublesex and mab-3 related transcription factor 1 2.87073
POU2AF1 POU class 2 associating factor 1 2.87073
FAM209A family with sequence similarity 209, member A 2.87073
C2CD4B C2 calcium-dependent domain containing 4B 2.87073
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 2.87073
CCL15 chemokine (C-C motif) ligand 15 2.87073
CD244 CD244 molecule, natural killer cell receptor 2B4 2.87073
SH2D1B SH2 domain containing 1B 2.87073
CXCR6 chemokine (C-X-C motif) receptor 6 2.87073
CSF1R colony stimulating factor 1 receptor 2.87073
ANKRD63 ankyrin repeat domain 63 2.87073
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 2.87073
FAM163A family with sequence similarity 163, member A 2.87073
NPFFR1 neuropeptide FF receptor 1 2.87073
TREH trehalase (brush-border membrane glycoprotein) 2.87073
CLEC4D C-type lectin domain family 4, member D 2.87073
CDH22 cadherin 22, type 2 2.87073
VWA2 von Willebrand factor A domain containing 2 2.87073
CLCA2 chloride channel accessory 2 2.87073
IFNK interferon, kappa 2.87073
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.87073
IFNE interferon, epsilon 2.87073
SPDEF SAM pointed domain containing ETS transcription factor 2.87073
FXYD3 FXYD domain containing ion transport regulator 3 2.87073
TGS1 trimethylguanosine synthase 1 2.87073
RDH16 retinol dehydrogenase 16 (all-trans) 2.87073
RAX retina and anterior neural fold homeobox 2.87073
LRRC24 leucine rich repeat containing 24 2.87073
ADRA2A adrenoceptor alpha 2A 2.87073
BPIFC BPI fold containing family C 2.87073
PADI4 peptidyl arginine deiminase, type IV 2.87073
TGM4 transglutaminase 4 2.87073
ITGA8 integrin, alpha 8 2.87073
EVC Ellis van Creveld protein 2.87073
CASQ2 calsequestrin 2 (cardiac muscle) 2.87073
CLCA4 chloride channel accessory 4 2.87073
IFITM10 interferon induced transmembrane protein 10 2.87073
TMEM86A transmembrane protein 86A 2.87073
LEP leptin 2.87073
ZBED6 zinc finger, BED-type containing 6 2.87073
FAM81B family with sequence similarity 81, member B 2.87073
KLHDC1 kelch domain containing 1 2.87073
ASCL3 achaete-scute family bHLH transcription factor 3 2.87073
REG1A regenerating islet-derived 1 alpha 2.87073
DMRTC1 DMRT-like family C1 2.87073
ESPNL espin-like 2.87073
HRG histidine-rich glycoprotein 2.87073
XCR1 chemokine (C motif) receptor 1 2.87073
FDPS farnesyl diphosphate synthase 2.8321
ZRANB3 zinc finger, RAN-binding domain containing 3 2.8321
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 2.81135
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.8018
SPTBN5 spectrin, beta, non-erythrocytic 5 2.8018
FHIT fragile histidine triad 2.76363
ZNF785 zinc finger protein 785 2.69675
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2.69652
PHF8 PHD finger protein 8 2.67385
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 2.62876
ZNF773 zinc finger protein 773 2.60716
CRIP1 cysteine-rich protein 1 (intestinal) 2.56185
CALM2 calmodulin 2 (phosphorylase kinase, delta) 2.55753
F12 coagulation factor XII (Hageman factor) 2.51456
HGD homogentisate 1,2-dioxygenase 2.46658
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 2.46658
MAP3K4-AS1 MAP3K4 antisense RNA 1 2.46658
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.45774
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2.45361
CFAP410 cilia and flagella associated protein 410 2.45016
TTBK2 tau tubulin kinase 2 2.42812
TMEM147 transmembrane protein 147 2.42186
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 2.42085
BAG6 BCL2-associated athanogene 6 2.42029
LASP1NB LASP1 neighbor 2.3249
STK38L serine/threonine kinase 38 like 2.31284
CPNE1 copine I 2.30268
MSH2 mutS homolog 2 2.26118
GAS2 growth arrest-specific 2 2.26118
CENPE centromere protein E, 312kDa 2.25697
CDK19 cyclin-dependent kinase 19 2.25248
TRIM69 tripartite motif containing 69 2.2366
HMGB2 high mobility group box 2 2.22777
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.22635
RLIM ring finger protein, LIM domain interacting 2.19446
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.19446
FOXO4 forkhead box O4 2.19219
KCTD15 potassium channel tetramerization domain containing 15 2.18589
RTEL1 regulator of telomere elongation helicase 1 2.1834
UBXN8 UBX domain protein 8 2.1737
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.16338
MRS2 MRS2 magnesium transporter 2.16338
HRAS Harvey rat sarcoma viral oncogene homolog 2.13591
PRPF6 pre-mRNA processing factor 6 2.13444
SLFN12 schlafen family member 12 2.12132
EID2B EP300 interacting inhibitor of differentiation 2B 2.11966
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 2.1059
MSL3 male-specific lethal 3 homolog (Drosophila) 2.10489
MSH5 mutS homolog 5 2.0966
PM20D2 peptidase M20 domain containing 2 2.08752
TOR3A torsin family 3, member A 2.08411
RSRC2 arginine/serine-rich coiled-coil 2 2.06546
B2M beta-2-microglobulin 2.06328
MRPS6 mitochondrial ribosomal protein S6 2.05802
FAM161A family with sequence similarity 161, member A 2.05802
SNX19 sorting nexin 19 2.05303
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 2.05303
CEP44 centrosomal protein 44kDa 2.04723
RPS20 ribosomal protein S20 2.04421
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 2.04323
C2CD3 C2 calcium-dependent domain containing 3 2.03442
ARMC1 armadillo repeat containing 1 2.03419
WWC3 WWC family member 3 2.03292
ARSJ arylsulfatase family, member J 2.03292
RAB20 RAB20, member RAS oncogene family 2.0308
PFKP phosphofructokinase, platelet 2.0308
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.0308
PRORP protein only RNase P catalytic subunit 2.02661
HRK harakiri, BCL2 interacting protein 2.0246
SH3BP1 SH3-domain binding protein 1 2.02055
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.01605

decreased expression

Symbol Name Standardized Value
CARNMT1 carnosine N-methyltransferase 1 -2.87073
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.87073
PRADC1 protease-associated domain containing 1 -2.87073
SALL4 spalt-like transcription factor 4 -2.87073
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.87073
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -2.87073
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -2.87073
SDE2 SDE2 telomere maintenance homolog (S. pombe) -2.87073
FOXD3 forkhead box D3 -2.87073
CHLSN cholesin -2.87073
CERS3 ceramide synthase 3 -2.87073
ATXN10 ataxin 10 -2.87073
EPHA5 EPH receptor A5 -2.87073
ADGRL1 adhesion G protein-coupled receptor L1 -2.87073
NKAIN2 Na+/K+ transporting ATPase interacting 2 -2.87073
LDAH lipid droplet associated hydrolase -2.87073
SMOX spermine oxidase -2.87073
CALY calcyon neuron-specific vesicular protein -2.87073
RNF187 ring finger protein 187 -2.87073
ERMAP erythroblast membrane-associated protein (Scianna blood group) -2.86364
DIO1 deiodinase, iodothyronine, type I -2.8321
SLC25A45 solute carrier family 25, member 45 -2.8321
ALOX15 arachidonate 15-lipoxygenase -2.8321
CFAP53 cilia and flagella associated protein 53 -2.8321
NXPH3 neurexophilin 3 -2.8321
MITF microphthalmia-associated transcription factor -2.8321
BIRC6 baculoviral IAP repeat containing 6 -2.8321
XKR8 XK, Kell blood group complex subunit-related family, member 8 -2.8321
BOLL boule-like RNA-binding protein -2.8321
AZIN2 antizyme inhibitor 2 -2.8321
CARD18 caspase recruitment domain family, member 18 -2.8321
KCNK7 potassium channel, two pore domain subfamily K, member 7 -2.8321
HLA-DMB major histocompatibility complex, class II, DM beta -2.8321
ADGRD1 adhesion G protein-coupled receptor D1 -2.8321
SHC4 SHC (Src homology 2 domain containing) family, member 4 -2.8321
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -2.8321
TLR3 toll-like receptor 3 -2.8321
ZFP92 ZFP92 zinc finger protein -2.8321
PCDHA13 protocadherin alpha 13 -2.8321
UPK3A uroplakin 3A -2.8321
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 -2.8321
SORCS3 sortilin-related VPS10 domain containing receptor 3 -2.8321
SIKE1 suppressor of IKBKE 1 -2.81187
STAC2 SH3 and cysteine rich domain 2 -2.76363
ANKFY1 ankyrin repeat and FYVE domain containing 1 -2.70292
NRCAM neuronal cell adhesion molecule -2.61963
ZNHIT6 zinc finger, HIT-type containing 6 -2.61625
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.5404
ZNF175 zinc finger protein 175 -2.51791
KIAA0753 KIAA0753 -2.51791
NALF2 NALCN channel auxiliary factor 2 -2.49085
TMEM69 transmembrane protein 69 -2.45954
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.42812
RAB4B RAB4B, member RAS oncogene family -2.40202
TCAF1 TRPM8 channel-associated factor 1 -2.40045
ITGA9 integrin, alpha 9 -2.37061
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.36771
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 -2.34362
CPM carboxypeptidase M -2.3249
FTCD formimidoyltransferase cyclodeaminase -2.3249
S1PR5 sphingosine-1-phosphate receptor 5 -2.3249
ZNF594 zinc finger protein 594 -2.32413
FXYD5 FXYD domain containing ion transport regulator 5 -2.31233
SETDB2 SET domain, bifurcated 2 -2.26968
ZXDB zinc finger, X-linked, duplicated B -2.26464
FAM184B family with sequence similarity 184, member B -2.26449
SSH2 slingshot protein phosphatase 2 -2.24993
SNX14 sorting nexin 14 -2.24575
NPW neuropeptide W -2.24149
CNOT12 CCR4-NOT transcription complex subunit 12 -2.2366
ZNF597 zinc finger protein 597 -2.2366
MAP2K5-DT MAP2K5 divergent transcript -2.2366
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C -2.22023
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -2.21501
YEATS4 YEATS domain containing 4 -2.21261
SCG5 secretogranin V -2.2079
CERT1 ceramide transporter 1 -2.19741
VEGFA vascular endothelial growth factor A -2.18951
KIF17 kinesin family member 17 -2.1834
ERI3 ERI1 exoribonuclease family member 3 -2.16398
KATNBL1 katanin p80 subunit B-like 1 -2.16038
RAB9B RAB9B, member RAS oncogene family -2.15989
PLTP phospholipid transfer protein -2.14978
RAI14 retinoic acid induced 14 -2.14721
DUS2 dihydrouridine synthase 2 -2.12322
ITGB8 integrin, beta 8 -2.12132
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 -2.12132
TRAF3IP2 TRAF3 interacting protein 2 -2.11966
CSF1 colony stimulating factor 1 (macrophage) -2.11966
PCGF3 polycomb group ring finger 3 -2.11966
EPS8 epidermal growth factor receptor pathway substrate 8 -2.08752
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -2.06546
CCDC175 coiled-coil domain containing 175 -2.05357
TENT5B terminal nucleotidyltransferase 5B -2.05357
CYYR1 cysteine/tyrosine-rich 1 -2.05357
MXI1 MAX interactor 1, dimerization protein -2.05357
TMEM248 transmembrane protein 248 -2.04215
ADGRL3 adhesion G protein-coupled receptor L3 -2.04042
ACBD7 acyl-CoA binding domain containing 7 -2.03292
BAD BCL2-associated agonist of cell death -2.03292
LARP7 La ribonucleoprotein domain family, member 7 -2.0308
MYO10 myosin X -2.0308
MBD4 methyl-CpG binding domain protein 4 -2.0308
DZIP3 DAZ interacting zinc finger protein 3 -2.02661
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -2.02661
ERCC6L2 excision repair cross-complementation group 6-like 2 -2.01503
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 -2.00817