THEMIS Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description thymocyte selection associated|This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 387357)
External Link https://ncbi.nlm.nih.gov/gene/387357
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Genes

500 genes differentially expressed following the THEMIS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0123458
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0110534
MMP12 matrix metallopeptidase 12 0.0109408
CD2 CD2 molecule 0.0109292
ENO2 enolase 2 (gamma, neuronal) 0.0107893
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0104586
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.0104124
CXCL9 chemokine (C-X-C motif) ligand 9 0.010274
NRN1 neuritin 1 0.0102264
EPHB2 EPH receptor B2 0.0100941
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00993486
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00981861
CLCA1 chloride channel accessory 1 0.00968307
FABP7 fatty acid binding protein 7, brain 0.00962544
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00925353
EGLN3 egl-9 family hypoxia-inducible factor 3 0.009071
PCP4 Purkinje cell protein 4 0.00905476
FGL2 fibrinogen-like 2 0.00890733
CCNB1 cyclin B1 0.00890141
GLUL glutamate-ammonia ligase 0.00885796
DCK deoxycytidine kinase 0.008841
NUSAP1 nucleolar and spindle associated protein 1 0.00881541
ADAMDEC1 ADAM-like, decysin 1 0.00872585
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.00870817
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00863548
RAD23B RAD23 homolog B (S. cerevisiae) 0.00844674
DHFR dihydrofolate reductase 0.00841348
GSTO1 glutathione S-transferase omega 1 0.0084065
PTTG1 pituitary tumor-transforming 1 0.00837734
GLO1 glyoxalase I 0.00837508
NOX1 NADPH oxidase 1 0.00837463
DUOX2 dual oxidase 2 0.00837017
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00835504
CXCL10 chemokine (C-X-C motif) ligand 10 0.008237
FAM162A family with sequence similarity 162, member A 0.00820515
CHKB choline kinase beta 0.00804565
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00801207
TOX3 TOX high mobility group box family member 3 0.00794652
TMEM106C transmembrane protein 106C 0.00774312
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00771547
FCGBP Fc fragment of IgG binding protein 0.0076758
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00764164
SRP9 signal recognition particle 9kDa 0.0076126
TFF3 trefoil factor 3 (intestinal) 0.00761125
SNX11 sorting nexin 11 0.00759928
HOPX HOP homeobox 0.00759504
CA9 carbonic anhydrase IX 0.00758831
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.0075165
CENPX centromere protein X 0.00747888
IL2RB interleukin 2 receptor, beta 0.00739447
NMU neuromedin U 0.00739118
HPF1 histone PARylation factor 1 0.0073806
TSPAN6 tetraspanin 6 0.00726889
GFAP glial fibrillary acidic protein 0.00726503
HLA-DMB major histocompatibility complex, class II, DM beta 0.00721076
ACOT13 acyl-CoA thioesterase 13 0.00720967
CXADR coxsackie virus and adenovirus receptor 0.00720478
CP ceruloplasmin (ferroxidase) 0.00719868
RAB32 RAB32, member RAS oncogene family 0.00717302
COMMD10 COMM domain containing 10 0.00713921
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00713864
SORD sorbitol dehydrogenase 0.00711799
ACP6 acid phosphatase 6, lysophosphatidic 0.00711678
PGAM1 phosphoglycerate mutase 1 (brain) 0.00709757
CIAO3 cytosolic iron-sulfur assembly component 3 0.00708923
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00706415
DPYSL3 dihydropyrimidinase-like 3 0.00706397
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00702453
IGFBP5 insulin-like growth factor binding protein 5 0.00702406
ADORA2B adenosine A2b receptor 0.0070232
CLEC7A C-type lectin domain family 7, member A 0.00700239
GPM6A glycoprotein M6A 0.00700175
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00695779
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00687933
CD99 CD99 molecule 0.00687816
IGSF6 immunoglobulin superfamily, member 6 0.00685988
FASN fatty acid synthase 0.00682108
CCR2 chemokine (C-C motif) receptor 2 0.00681317
LEFTY1 left-right determination factor 1 0.00679649
GANAB glucosidase, alpha; neutral AB 0.00679464
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.0067941
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00676864
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00676544
CPVL carboxypeptidase, vitellogenic-like 0.00675335
COPS4 COP9 signalosome subunit 4 0.00675149
CALD1 caldesmon 1 0.00674698
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.00672587
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00670504
SELENOF selenoprotein F 0.00665222
TMPO thymopoietin 0.00663941
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00662143
H2AX H2A.X variant histone 0.00661822
STK38L serine/threonine kinase 38 like 0.00660974
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00660551
MRPL42 mitochondrial ribosomal protein L42 0.00659056
FZD5 frizzled class receptor 5 0.00652304
HILPDA hypoxia inducible lipid droplet-associated 0.00651599
ATP5PD ATP synthase peripheral stalk subunit d 0.00651433
FGFR3 fibroblast growth factor receptor 3 0.00650551
TMEM14B transmembrane protein 14B 0.00650303
SV2A synaptic vesicle glycoprotein 2A 0.00644549
CD52 CD52 molecule 0.00643926
HINT1 histidine triad nucleotide binding protein 1 0.00643069
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0064304
REG1A regenerating islet-derived 1 alpha 0.00642253
RGS10 regulator of G-protein signaling 10 0.00642223
SOX9 SRY (sex determining region Y)-box 9 0.00638752
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00638256
PCLAF PCNA clamp associated factor 0.00635142
ADARB1 adenosine deaminase, RNA-specific, B1 0.00633908
WDR61 WD repeat domain 61 0.00632837
GJA1 gap junction protein, alpha 1, 43kDa 0.00632434
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00629417
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00628726
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00627223
HOXB13 homeobox B13 0.00626592
CLDND1 claudin domain containing 1 0.00625483
FYB1 FYN binding protein 1 0.00623421
KIF20A kinesin family member 20A 0.00620453
CYC1 cytochrome c-1 0.00620355
SPTSSA serine palmitoyltransferase, small subunit A 0.00620039
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00619276
GZMK granzyme K (granzyme 3; tryptase II) 0.00619131
ECI2 enoyl-CoA delta isomerase 2 0.00618741
GET1 guided entry of tail-anchored proteins factor 1 0.00618608
REG3A regenerating islet-derived 3 alpha 0.00618185
CLEC10A C-type lectin domain family 10, member A 0.00617522
GTF2A2 general transcription factor IIA, 2, 12kDa 0.00616055
KRT20 keratin 20, type I 0.00615662
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00614143
PTK2 protein tyrosine kinase 2 0.00613666
CRLF1 cytokine receptor-like factor 1 0.00612559
GAP43 growth associated protein 43 0.00612267
PGK1 phosphoglycerate kinase 1 0.00612207
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00611857
CEMIP cell migration inducing protein, hyaluronan binding 0.00611305
PIGR polymeric immunoglobulin receptor 0.00610134
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00609494
PLEK2 pleckstrin 2 0.00609111
CNTNAP2 contactin associated protein-like 2 0.00608329
SELENOT selenoprotein T 0.00599582
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00598374
SREBF1 sterol regulatory element binding transcription factor 1 0.00598332
CPE carboxypeptidase E 0.00597808
CCNA2 cyclin A2 0.00597322
CD8A CD8a molecule 0.00596491
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00596177
TBCA tubulin folding cofactor A 0.0059338
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00593155
NPM3 nucleophosmin/nucleoplasmin 3 0.00589693
ADAM28 ADAM metallopeptidase domain 28 0.0058925
FOXF1 forkhead box F1 0.00587727
WFDC1 WAP four-disulfide core domain 1 0.00587719
ATP10B ATPase, class V, type 10B 0.00587667
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00586495
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.00586156
RXRA retinoid X receptor, alpha 0.00582246
TMEM126B transmembrane protein 126B 0.00582169
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00581973
RANBP1 RAN binding protein 1 0.00581618
ACTL6A actin-like 6A 0.00580694
GPA33 glycoprotein A33 (transmembrane) 0.00578161
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.0057646
KIF1B kinesin family member 1B 0.00576307
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00574423
ASF1A anti-silencing function 1A histone chaperone 0.00574335
SCRG1 stimulator of chondrogenesis 1 0.00573425
TMEM14A transmembrane protein 14A 0.00573305
LMNB1 lamin B1 0.00572618
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00572487
SRSF1 serine/arginine-rich splicing factor 1 0.0056939
CD48 CD48 molecule 0.0056902
SAP30 Sin3A-associated protein, 30kDa 0.00567411
RPA3 replication protein A3, 14kDa 0.00566281
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.0056518
PSRC1 proline/serine-rich coiled-coil 1 0.00562239
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0056004
NDRG1 N-myc downstream regulated 1 0.0055988
NUP37 nucleoporin 37kDa 0.00559199
NTS neurotensin 0.00558087
CRIP2 cysteine-rich protein 2 0.00557462
CBX1 chromobox homolog 1 0.00556746
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00556384
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00555411
OIP5 Opa interacting protein 5 0.00555303
AIF1 allograft inflammatory factor 1 0.00553708
MRPL39 mitochondrial ribosomal protein L39 0.00552791
CAAP1 caspase activity and apoptosis inhibitor 1 0.00551665
ITM2A integral membrane protein 2A 0.00550551
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.0054945
PTPRO protein tyrosine phosphatase, receptor type, O 0.00548329
CANX calnexin 0.00547948
HIRA histone cell cycle regulator 0.00547637
SDC2 syndecan 2 0.00546984
NDUFA4 NDUFA4, mitochondrial complex associated 0.00542579
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.0054207
TMPRSS4 transmembrane protease, serine 4 0.00540744
VDAC3 voltage-dependent anion channel 3 0.00540103
CDK1 cyclin-dependent kinase 1 0.00537679
PAX6 paired box 6 0.00536951
AMD1 adenosylmethionine decarboxylase 1 0.00536942
HMGB1 high mobility group box 1 0.00536787
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.00536669
AQP4 aquaporin 4 0.005364
HPR haptoglobin-related protein 0.00535114
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.0053503
TGFBI transforming growth factor, beta-induced, 68kDa 0.00534609
HPGDS hematopoietic prostaglandin D synthase 0.00533398
DDHD2 DDHD domain containing 2 0.00533171
INSIG1 insulin induced gene 1 0.00532601
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00532384
MAT2B methionine adenosyltransferase II, beta 0.00530754
RACGAP1 Rac GTPase activating protein 1 0.0052904
RRM2 ribonucleotide reductase M2 0.00525005
IL2RG interleukin 2 receptor, gamma 0.00523186
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.0052304
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.00522657
CD33 CD33 molecule 0.00522066
COX7B cytochrome c oxidase subunit VIIb 0.00521495
FPR3 formyl peptide receptor 3 0.00520716
HNMT histamine N-methyltransferase 0.00520122
ENO1 enolase 1, (alpha) 0.00519895
RHOA ras homolog family member A 0.00519782
CDKN3 cyclin-dependent kinase inhibitor 3 0.00519264
SEPP1 selenoprotein P, plasma, 1 0.00518002
MEA1 male-enhanced antigen 1 0.00517513
NCK1 NCK adaptor protein 1 0.00517007
STMN1 stathmin 1 0.00516888
S100A8 S100 calcium binding protein A8 0.00516862
CD300A CD300a molecule 0.00516472
VBP1 von Hippel-Lindau binding protein 1 0.00515686
TPI1 triosephosphate isomerase 1 0.00514943
ZG16 zymogen granule protein 16 0.0051436
TMSB15A thymosin beta 15a 0.00513781
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00513328
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00510641
NELL2 NEL-like 2 (chicken) 0.0051053
CHI3L2 chitinase 3-like 2 0.0050947
ATP5PF ATP synthase peripheral stalk subunit F6 0.0050932
REG1B regenerating islet-derived 1 beta 0.00509165
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00508614
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00508269
SNCAIP synuclein, alpha interacting protein 0.00507991
SRP72 signal recognition particle 72kDa 0.00506714
RWDD1 RWD domain containing 1 0.0050651
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.00505895
CCDC47 coiled-coil domain containing 47 0.00504151
GSTT1 glutathione S-transferase theta 1 0.00503843
IDO1 indoleamine 2,3-dioxygenase 1 0.0050371
BIN2 bridging integrator 2 0.00502961

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -0.0205185
IFI27 interferon, alpha-inducible protein 27 -0.0175935
KRT14 keratin 14, type I -0.0175247
MX1 MX dynamin-like GTPase 1 -0.0146687
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0144834
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.0140525
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0137285
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0132509
CRYAB crystallin, alpha B -0.0131865
MGLL monoglyceride lipase -0.0130934
PEG10 paternally expressed 10 -0.0129881
G0S2 G0/G1 switch 2 -0.0129802
TACSTD2 tumor-associated calcium signal transducer 2 -0.0129358
KRT23 keratin 23, type I -0.0129357
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0124408
KRT19 keratin 19, type I -0.0123575
SFRP1 secreted frizzled-related protein 1 -0.0122103
TFPI2 tissue factor pathway inhibitor 2 -0.0118939
CRABP2 cellular retinoic acid binding protein 2 -0.0114962
ADGRL2 adhesion G protein-coupled receptor L2 -0.0112975
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.0111651
CXCL6 chemokine (C-X-C motif) ligand 6 -0.0111394
SRPX sushi-repeat containing protein, X-linked -0.0108125
ASS1 argininosuccinate synthase 1 -0.0106963
DEFB1 defensin, beta 1 -0.0106689
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0106461
CCN2 cellular communication network factor 2 -0.0105995
STK10 serine/threonine kinase 10 -0.0103903
SIK1 salt-inducible kinase 1 -0.0103166
RRAD Ras-related associated with diabetes -0.0102713
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0102074
MT1X metallothionein 1X -0.0101082
RRAGD Ras-related GTP binding D -0.0100035
PLK2 polo-like kinase 2 -0.00997589
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00966632
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.0096518
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00963502
BST2 bone marrow stromal cell antigen 2 -0.00961524
KRT15 keratin 15, type I -0.00959909
CHRDL1 chordin-like 1 -0.0095771
TGFBR3 transforming growth factor, beta receptor III -0.00957101
ARHGAP29 Rho GTPase activating protein 29 -0.00949763
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00947895
DUSP5 dual specificity phosphatase 5 -0.00946521
TSPYL5 TSPY-like 5 -0.00942202
JAK1 Janus kinase 1 -0.00933285
GPX7 glutathione peroxidase 7 -0.00929808
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00926032
MVP major vault protein -0.00923601
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00922707
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00913265
ISG15 ISG15 ubiquitin-like modifier -0.00902449
KRT5 keratin 5, type II -0.0090114
IL6 interleukin 6 -0.00900915
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0089885
IER5 immediate early response 5 -0.00898481
BMP2 bone morphogenetic protein 2 -0.00881919
ATF3 activating transcription factor 3 -0.00878594
FOSL2 FOS-like antigen 2 -0.00873287
MMP7 matrix metallopeptidase 7 -0.00872454
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00871575
GAS1 growth arrest-specific 1 -0.00868845
COL1A1 collagen, type I, alpha 1 -0.00863138
CRISP3 cysteine-rich secretory protein 3 -0.00862231
EGFL6 EGF-like-domain, multiple 6 -0.00861537
FABP4 fatty acid binding protein 4, adipocyte -0.00859085
MT1E metallothionein 1E -0.00854966
FMO1 flavin containing monooxygenase 1 -0.00849452
ECM1 extracellular matrix protein 1 -0.00849054
MAMLD1 mastermind-like domain containing 1 -0.00845298
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00843325
GPX3 glutathione peroxidase 3 -0.00841375
GOLGA8H golgin A8 family, member H -0.00840401
PDZK1 PDZ domain containing 1 -0.00839524
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00831072
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00830131
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00825102
IL1R1 interleukin 1 receptor, type I -0.00824573
ADCY9 adenylate cyclase 9 -0.00822008
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00821674
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00819506
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00818146
ARMCX1 armadillo repeat containing, X-linked 1 -0.00815829
KRT7 keratin 7, type II -0.00813837
IL1B interleukin 1, beta -0.00811258
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00809366
BTG2 BTG family, member 2 -0.00809173
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00808113
NT5E 5'-nucleotidase, ecto (CD73) -0.00806625
MDK midkine (neurite growth-promoting factor 2) -0.00805952
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00805225
OXTR oxytocin receptor -0.00799026
THBD thrombomodulin -0.00793899
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00791096
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00789757
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00789568
BICC1 BicC family RNA binding protein 1 -0.0078733
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.00787018
S100A11 S100 calcium binding protein A11 -0.0078326
CD93 CD93 molecule -0.00775492
TRIM22 tripartite motif containing 22 -0.00774173
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.0077204
TGFA transforming growth factor, alpha -0.00770185
HSPB8 heat shock 22kDa protein 8 -0.00765692
PBX3 pre-B-cell leukemia homeobox 3 -0.00763833
CFB complement factor B -0.00762653
TNNC1 troponin C type 1 (slow) -0.00759872
AKR1C2 aldo-keto reductase family 1, member C2 -0.00759438
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00756994
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.00753223
IL1RN interleukin 1 receptor antagonist -0.00752703
RFTN1 raftlin, lipid raft linker 1 -0.0075181
ACAA1 acetyl-CoA acyltransferase 1 -0.00751398
ADIRF adipogenesis regulatory factor -0.00749598
MX2 MX dynamin-like GTPase 2 -0.00744776
MGP matrix Gla protein -0.00742826
AMOTL2 angiomotin like 2 -0.00742251
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00741273
RCAN1 regulator of calcineurin 1 -0.0073722
IGFBP6 insulin-like growth factor binding protein 6 -0.0073639
E2F2 E2F transcription factor 2 -0.00735283
COL16A1 collagen, type XVI, alpha 1 -0.00735265
INAVA innate immunity activator -0.00734809
ANPEP alanyl (membrane) aminopeptidase -0.00734756
EGR1 early growth response 1 -0.00733032
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00732658
TAC1 tachykinin, precursor 1 -0.00729519
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00729426
VAMP8 vesicle-associated membrane protein 8 -0.00727569
PPIF peptidylprolyl isomerase F -0.00725597
IFI6 interferon, alpha-inducible protein 6 -0.0071992
KAZN kazrin, periplakin interacting protein -0.00719671
STC2 stanniocalcin 2 -0.00719396
HOMER1 homer scaffolding protein 1 -0.00718235
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00716894
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00715507
IRF7 interferon regulatory factor 7 -0.0071462
FAM110B family with sequence similarity 110, member B -0.00712383
PTN pleiotrophin -0.0071226
MMP1 matrix metallopeptidase 1 -0.00710635
KLK5 kallikrein-related peptidase 5 -0.00710438
LCN2 lipocalin 2 -0.00708387
LMCD1 LIM and cysteine-rich domains 1 -0.00707806
KLHL41 kelch-like family member 41 -0.00707437
SCGB2A2 secretoglobin, family 2A, member 2 -0.00705825
PDZK1IP1 PDZK1 interacting protein 1 -0.00705575
DPP4 dipeptidyl-peptidase 4 -0.00704708
MATN2 matrilin 2 -0.00701289
EDNRA endothelin receptor type A -0.00699884
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00698107
MT1HL1 metallothionein 1H-like 1 -0.00693264
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00692618
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00691739
MT1G metallothionein 1G -0.00691308
PROM1 prominin 1 -0.0068752
COL15A1 collagen, type XV, alpha 1 -0.00687087
CES1 carboxylesterase 1 -0.00686978
HIST1H2BK histone cluster 1, H2bk -0.00686162
OSBPL9 oxysterol binding protein-like 9 -0.00684614
SLC43A3 solute carrier family 43, member 3 -0.00684312
CYBA cytochrome b-245, alpha polypeptide -0.00683521
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00683287
AOX1 aldehyde oxidase 1 -0.00682464
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0068163
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00680666
LAMC2 laminin, gamma 2 -0.00679481
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00677981
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.00677174
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00675696
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00674431
JMJD1C jumonji domain containing 1C -0.00673225
ZNF423 zinc finger protein 423 -0.00672756
HMOX1 heme oxygenase 1 -0.00672278
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00671351
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0067122
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00670697
CKM creatine kinase, muscle -0.00670173
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00669929
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00669027
TNIP1 TNFAIP3 interacting protein 1 -0.00668877
SMAD3 SMAD family member 3 -0.00668845
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00667934
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00664743
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00663427
NEU1 sialidase 1 (lysosomal sialidase) -0.00661608
QPRT quinolinate phosphoribosyltransferase -0.0066062
MT1H metallothionein 1H -0.00658543
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00654726
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00654558
SLPI secretory leukocyte peptidase inhibitor -0.00653264
LAMA2 laminin, alpha 2 -0.00653047
PDZD2 PDZ domain containing 2 -0.00652666
KLK11 kallikrein-related peptidase 11 -0.00649706
CLIC5 chloride intracellular channel 5 -0.00644484
AQP1 aquaporin 1 (Colton blood group) -0.00643846
TRIP6 thyroid hormone receptor interactor 6 -0.00642642
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00642035
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00640929
TCL1A T-cell leukemia/lymphoma 1A -0.00638918
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00638783
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00638554
BIN1 bridging integrator 1 -0.00638508
OSR2 odd-skipped related transciption factor 2 -0.00637905
CARD10 caspase recruitment domain family, member 10 -0.00637742
KLK10 kallikrein-related peptidase 10 -0.0063562
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00633727
TNNI2 troponin I type 2 (skeletal, fast) -0.00633313
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00633112
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00632339
NOTCH2NL notch 2 N-terminal like -0.00631598
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00628102
TMEM100 transmembrane protein 100 -0.00626956
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00625508
SGCE sarcoglycan, epsilon -0.00624
IL1A interleukin 1, alpha -0.00622789
PDGFC platelet derived growth factor C -0.00622467
SCGB2A1 secretoglobin, family 2A, member 1 -0.00621567
MT1M metallothionein 1M -0.00620564
BAG3 BCL2-associated athanogene 3 -0.00619831
RET ret proto-oncogene -0.00619384
VPREB1 pre-B lymphocyte 1 -0.00617746
LAMP3 lysosomal-associated membrane protein 3 -0.00617527
GPR137B G protein-coupled receptor 137B -0.00617047
RRAGC Ras-related GTP binding C -0.00616286
NEFH neurofilament, heavy polypeptide -0.00614095
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00613829
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00613162
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00611919
MME membrane metallo-endopeptidase -0.00609581
UGCG UDP-glucose ceramide glucosyltransferase -0.00609046
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00607712
TTC39A tetratricopeptide repeat domain 39A -0.00605512
MSLN mesothelin -0.00604497
CLDN5 claudin 5 -0.00603158
DLK1 delta-like 1 homolog (Drosophila) -0.00602627
RBM47 RNA binding motif protein 47 -0.00602602
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00601826
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00601251
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00601044
COL4A1 collagen, type IV, alpha 1 -0.00599752
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00598367
ZBED2 zinc finger, BED-type containing 2 -0.00598166
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -0.00596944
PXDN peroxidasin -0.00594911
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.00594746
CAVIN3 caveolae associated protein 3 -0.00594323
GLOD4 glyoxalase domain containing 4 -0.00593266
SETBP1 SET binding protein 1 -0.00592984
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00592171
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00591835