THRA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description thyroid hormone receptor, alpha|The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7067)
External Link https://ncbi.nlm.nih.gov/gene/7067
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Genes

498 genes differentially expressed following the THRA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00828019
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00814308
CA2 carbonic anhydrase II 0.0080027
CRABP2 cellular retinoic acid binding protein 2 0.00799354
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00796345
MAL mal, T-cell differentiation protein 0.00786581
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00784805
KLF6 Kruppel-like factor 6 0.00748059
CLEC11A C-type lectin domain family 11, member A 0.0074778
DEFB1 defensin, beta 1 0.00743026
S100A7 S100 calcium binding protein A7 0.00741664
RHCG Rh family, C glycoprotein 0.00712637
SPRR3 small proline-rich protein 3 0.00709122
COG7 component of oligomeric golgi complex 7 0.00695404
OXA1L oxidase (cytochrome c) assembly 1-like 0.0069277
XPO7 exportin 7 0.00664765
KRT13 keratin 13, type I 0.0065146
HSPA1A heat shock 70kDa protein 1A 0.00649913
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00643819
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00640523
SET SET nuclear proto-oncogene 0.00637193
S100A10 S100 calcium binding protein A10 0.00627422
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00624758
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0062042
PXDN peroxidasin 0.00613165
MELK maternal embryonic leucine zipper kinase 0.0061206
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00605107
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00595361
CRYBG1 crystallin beta-gamma domain containing 1 0.00592648
PITX1 paired-like homeodomain 1 0.0058743
LTA4H leukotriene A4 hydrolase 0.00585422
RPL10 ribosomal protein L10 0.00579486
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00576097
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00576079
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00576041
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00572279
EMX2 empty spiracles homeobox 2 0.00569869
RSL1D1 ribosomal L1 domain containing 1 0.005641
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00561196
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00560877
KRT18 keratin 18, type I 0.00559786
TPM2 tropomyosin 2 (beta) 0.00556722
ANXA2P2 annexin A2 pseudogene 2 0.00554423
GAB2 GRB2-associated binding protein 2 0.00552806
TMEM230 transmembrane protein 230 0.0054642
PLK1 polo-like kinase 1 0.00544292
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00544141
RFC2 replication factor C (activator 1) 2, 40kDa 0.00542082
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00537784
MTF2 metal response element binding transcription factor 2 0.00530789
DDR2 discoidin domain receptor tyrosine kinase 2 0.00525816
PTK2 protein tyrosine kinase 2 0.0052553
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00517959
PRMT5 protein arginine methyltransferase 5 0.00516434
EDN3 endothelin 3 0.00514905
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.00514712
FOLR1 folate receptor 1 (adult) 0.0051421
JPT1 Jupiter microtubule associated homolog 1 0.00513888
TFPI2 tissue factor pathway inhibitor 2 0.00513682
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.00512801
BST2 bone marrow stromal cell antigen 2 0.00507463
MED6 mediator complex subunit 6 0.00507445
ZMYND8 zinc finger, MYND-type containing 8 0.00506983
PODXL podocalyxin-like 0.00506019
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.00505958
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.0050457
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00501174
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00500804
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00500344
IFRD2 interferon-related developmental regulator 2 0.00499769
ANXA2 annexin A2 0.00498765
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0049834
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00497045
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00495129
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00490043
ELANE elastase, neutrophil expressed 0.00489727
ZNF185 zinc finger protein 185 (LIM domain) 0.00489635
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00489541
H1-10 H1.10 linker histone 0.00488505
PSCA prostate stem cell antigen 0.00487025
GUCY2C guanylate cyclase 2C 0.00484355
RGCC regulator of cell cycle 0.00482378
OAZ1 ornithine decarboxylase antizyme 1 0.00479914
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00479222
KRT7 keratin 7, type II 0.00476949
BMP2 bone morphogenetic protein 2 0.00476884
MSLN mesothelin 0.00476539
TM4SF1 transmembrane 4 L six family member 1 0.00476301
PDZK1IP1 PDZK1 interacting protein 1 0.00474162
CDC42 cell division cycle 42 0.00473554
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00473371
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00471547
DNTT DNA nucleotidylexotransferase 0.00468339
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.0046776
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.0046761
CAV2 caveolin 2 0.00464495
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00463177
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.00461897
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00461716
RASA4 RAS p21 protein activator 4 0.00459921
SHCBP1 SHC SH2-domain binding protein 1 0.00459917
PCNA proliferating cell nuclear antigen 0.0045865
DMAC2L distal membrane arm assembly component 2 like 0.00458085
UBXN7 UBX domain protein 7 0.00452467
LIG1 ligase I, DNA, ATP-dependent 0.00451685
SPRY4 sprouty homolog 4 (Drosophila) 0.00450144
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00449924
RPP14 ribonuclease P/MRP 14kDa subunit 0.00449223
SRPX2 sushi-repeat containing protein, X-linked 2 0.00448114
ZYX zyxin 0.00446937
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00444742
SKA1 spindle and kinetochore associated complex subunit 1 0.0044418
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00444083
FGFR1 fibroblast growth factor receptor 1 0.00443297
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00443088
KLK8 kallikrein-related peptidase 8 0.00442064
RHOA ras homolog family member A 0.00442009
GOLGA8A golgin A8 family, member A 0.00440394
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00440154
AHNAK AHNAK nucleoprotein 0.00440108
CHEK1 checkpoint kinase 1 0.00439256
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.00438563
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.00438125
HSPA8 heat shock 70kDa protein 8 0.00437792
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00435804
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00435132
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.004342
LY6D lymphocyte antigen 6 complex, locus D 0.0043267
C8ORF4 chromosome 8 open reading frame 4 0.00432657
LASP1 LIM and SH3 protein 1 0.00432611
PRMT1 protein arginine methyltransferase 1 0.00431395
TXNL4A thioredoxin-like 4A 0.00431333
SFRP1 secreted frizzled-related protein 1 0.00431212
MECOM MDS1 and EVI1 complex locus 0.00428935
BCL6 B-cell CLL/lymphoma 6 0.00428291
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00427875
SPRR1A small proline-rich protein 1A 0.00427715
CTTN cortactin 0.00427495
TDP1 tyrosyl-DNA phosphodiesterase 1 0.0042673
KDM5D lysine (K)-specific demethylase 5D 0.00426637
NKTR natural killer cell triggering receptor 0.00425639
DMTF1 cyclin D binding myb-like transcription factor 1 0.00424262
KLK5 kallikrein-related peptidase 5 0.00423747
PI3 peptidase inhibitor 3, skin-derived 0.0042364
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00422885
BCAR3 breast cancer anti-estrogen resistance 3 0.0042127
RGS5 regulator of G-protein signaling 5 0.00420321
LIAS lipoic acid synthetase 0.00419324
HEATR1 HEAT repeat containing 1 0.00417947
ANGPT2 angiopoietin 2 0.00416279
CDC123 cell division cycle 123 0.0041599
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00415944
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.0041579
ECPAS Ecm29 proteasome adaptor and scaffold 0.00415733
HAUS4 HAUS augmin-like complex, subunit 4 0.00415095
RAN RAN, member RAS oncogene family 0.00414976
CGRRF1 cell growth regulator with ring finger domain 1 0.0041457
PSAP prosaposin 0.00414096
GDI2 GDP dissociation inhibitor 2 0.00412025
EPHA2 EPH receptor A2 0.00411321
MICA MHC class I polypeptide-related sequence A 0.00411049
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.00409168
MBD1 methyl-CpG binding domain protein 1 0.00409157
CNPY2 canopy FGF signaling regulator 2 0.00408928
BHLHE41 basic helix-loop-helix family, member e41 0.00408673
ERP29 endoplasmic reticulum protein 29 0.00408669
SSR4 signal sequence receptor, delta 0.00408131
SMAD3 SMAD family member 3 0.0040812
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00407201
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.00406904
NHP2 NHP2 ribonucleoprotein 0.00406868
KLK10 kallikrein-related peptidase 10 0.00406571
ATP5F1B ATP synthase F1 subunit beta 0.00405936
TUBB2A tubulin, beta 2A class IIa 0.00405748
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00405232
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00404827
RBBP4 retinoblastoma binding protein 4 0.00404729
KLK7 kallikrein-related peptidase 7 0.00404505
FLT3 fms-related tyrosine kinase 3 0.00403608
GMDS GDP-mannose 4,6-dehydratase 0.00403561
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00401669
TGM1 transglutaminase 1 0.00401525
TNNC1 troponin C type 1 (slow) 0.00401485
NBEAL2 neurobeachin-like 2 0.00401405
STON1 stonin 1 0.00400938
BFAR bifunctional apoptosis regulator 0.00400634
SLPI secretory leukocyte peptidase inhibitor 0.00400259
SPRR2B small proline-rich protein 2B 0.00400256
NOD2 nucleotide-binding oligomerization domain containing 2 0.00399539
MPO myeloperoxidase 0.00399048
FOXL2 forkhead box L2 0.00398985
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00398868
VAMP5 vesicle-associated membrane protein 5 0.00398035
RPS9 ribosomal protein S9 0.00397932
ACAA1 acetyl-CoA acyltransferase 1 0.00396913
ANOS1 anosmin 1 0.00396731
HSPB1 heat shock 27kDa protein 1 0.00395245
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00394662
ZNF83 zinc finger protein 83 0.00393832
COQ8A coenzyme Q8A 0.00393513
FZD4 frizzled class receptor 4 0.0039284
PEBP1 phosphatidylethanolamine binding protein 1 0.00392828
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00392623
FLT1 fms-related tyrosine kinase 1 0.003926
ADAT1 adenosine deaminase, tRNA-specific 1 0.00392401
ZNF44 zinc finger protein 44 0.00392337
AK2 adenylate kinase 2 0.00391828
PTEN phosphatase and tensin homolog 0.00391507
PLIN3 perilipin 3 0.00391242
DSTYK dual serine/threonine and tyrosine protein kinase 0.00390818
SPRED2 sprouty-related, EVH1 domain containing 2 0.00390801
GRHPR glyoxylate reductase/hydroxypyruvate reductase 0.00390542
ADGRL2 adhesion G protein-coupled receptor L2 0.0039024
GUSBP3 glucuronidase, beta pseudogene 3 0.00390196
IER3 immediate early response 3 0.00389785
ZFYVE21 zinc finger, FYVE domain containing 21 0.00389763
LRRC37A3 leucine rich repeat containing 37, member A3 0.00389666
IL15 interleukin 15 0.00389621
GMPR2 guanosine monophosphate reductase 2 0.00389611
NOP56 NOP56 ribonucleoprotein 0.00388805
MRPS16 mitochondrial ribosomal protein S16 0.00388441
RPL14 ribosomal protein L14 0.00388261
DALRD3 DALR anticodon binding domain containing 3 0.00387727
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00387123
FZD2 frizzled class receptor 2 0.00386982
FLNA filamin A, alpha 0.0038691
SYNGR3 synaptogyrin 3 0.00386599
CD200 CD200 molecule 0.00386131
GINS4 GINS complex subunit 4 (Sld5 homolog) 0.00385941
FZD7 frizzled class receptor 7 0.003857
MCL1 myeloid cell leukemia 1 0.00385043
PRKCA protein kinase C, alpha 0.00384709
CAPNS1 calpain, small subunit 1 0.00383362
EIF4A1 eukaryotic translation initiation factor 4A1 0.00383186
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.00382829
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00382516
SFSWAP splicing factor, suppressor of white-apricot family 0.00381073
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00380983
RET ret proto-oncogene 0.00380857
MME membrane metallo-endopeptidase 0.00380778
PPARG peroxisome proliferator-activated receptor gamma 0.00380436
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00380288
DIAPH2 diaphanous-related formin 2 0.00379986
FOSL1 FOS-like antigen 1 0.00379371
TRAK1 trafficking protein, kinesin binding 1 0.00379103
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.003782
MPHOSPH8 M-phase phosphoprotein 8 0.00378016
SOX17 SRY (sex determining region Y)-box 17 0.00377775
DZIP1 DAZ interacting zinc finger protein 1 0.00377203
OSBPL1A oxysterol binding protein-like 1A 0.00377163

decreased expression

Symbol Name Standardized Value
APOD apolipoprotein D -0.0114869
ZIC1 Zic family member 1 -0.0112465
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.011112
TPSAB1 tryptase alpha/beta 1 -0.00958689
LTF lactotransferrin -0.00943578
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00883708
MAP7 microtubule-associated protein 7 -0.00880683
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00865422
GPNMB glycoprotein (transmembrane) nmb -0.00848332
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00818959
TDO2 tryptophan 2,3-dioxygenase -0.00813814
PCP4 Purkinje cell protein 4 -0.00808339
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00795891
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00792076
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00791695
OLFM4 olfactomedin 4 -0.00779538
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00777945
LUM lumican -0.00775779
ZBTB18 zinc finger and BTB domain containing 18 -0.00758256
CD163 CD163 molecule -0.00754316
PMP22 peripheral myelin protein 22 -0.00749664
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00745109
TYROBP TYRO protein tyrosine kinase binding protein -0.00733378
MMP9 matrix metallopeptidase 9 -0.00724911
IGFBP1 insulin-like growth factor binding protein 1 -0.00722695
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00719119
NIBAN1 niban apoptosis regulator 1 -0.00718401
FTH1 ferritin, heavy polypeptide 1 -0.00717613
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00709793
PID1 phosphotyrosine interaction domain containing 1 -0.00707263
SEPP1 selenoprotein P, plasma, 1 -0.00702726
C1QA complement component 1, q subcomponent, A chain -0.00701896
STK26 serine/threonine protein kinase 26 -0.00700368
CPA3 carboxypeptidase A3 (mast cell) -0.00687956
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00682442
IFI6 interferon, alpha-inducible protein 6 -0.00679638
POSTN periostin, osteoblast specific factor -0.0067091
A2M alpha-2-macroglobulin -0.00663675
CHN2 chimerin 2 -0.0066269
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00658209
C3AR1 complement component 3a receptor 1 -0.00655106
TXNIP thioredoxin interacting protein -0.00652444
CCL19 chemokine (C-C motif) ligand 19 -0.00650195
H1-2 H1.2 linker histone, cluster member -0.00638928
ASPN asporin -0.00630538
EFNB2 ephrin-B2 -0.00628931
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00628306
C1QB complement component 1, q subcomponent, B chain -0.00626739
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00624424
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00624368
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00618398
CD84 CD84 molecule -0.00615859
PTPRD protein tyrosine phosphatase, receptor type, D -0.00614429
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00613969
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00613384
CTSK cathepsin K -0.0061291
ADAMDEC1 ADAM-like, decysin 1 -0.00606328
FUCA1 fucosidase, alpha-L- 1, tissue -0.00603296
F13A1 coagulation factor XIII, A1 polypeptide -0.00602572
DCN decorin -0.00599108
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00597161
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00596383
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00591859
RRAGA Ras-related GTP binding A -0.00587264
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00586455
RAPSN receptor-associated protein of the synapse -0.00585317
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00585203
RNF19B ring finger protein 19B -0.00582479
PTK2B protein tyrosine kinase 2 beta -0.0058104
SDC3 syndecan 3 -0.00580975
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00578507
PDLIM3 PDZ and LIM domain 3 -0.00577987
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00577706
MT1M metallothionein 1M -0.00577485
TMEM176B transmembrane protein 176B -0.00572154
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00569961
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0056985
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.00567841
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00566792
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00565162
CHI3L2 chitinase 3-like 2 -0.00564517
IL1R1 interleukin 1 receptor, type I -0.00563143
SCRG1 stimulator of chondrogenesis 1 -0.00561767
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00561579
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00560875
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00558057
MFAP3L microfibrillar-associated protein 3-like -0.00556683
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00554565
XCL1 chemokine (C motif) ligand 1 -0.00554359
PLBD1 phospholipase B domain containing 1 -0.00553172
SOX9 SRY (sex determining region Y)-box 9 -0.00552471
ANPEP alanyl (membrane) aminopeptidase -0.00550297
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.0055008
COL11A1 collagen, type XI, alpha 1 -0.00550035
CD38 CD38 molecule -0.00549892
TSPAN4 tetraspanin 4 -0.00549224
PLPP3 phospholipid phosphatase 3 -0.00548887
TEX30 testis expressed 30 -0.0054527
BASP1 brain abundant, membrane attached signal protein 1 -0.00544524
GFAP glial fibrillary acidic protein -0.00544051
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00543624
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00543513
COL6A3 collagen, type VI, alpha 3 -0.0054329
HNMT histamine N-methyltransferase -0.00542534
SUB1 SUB1 homolog (S. cerevisiae) -0.00540569
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00539932
ELN elastin -0.0053767
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00536778
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0053616
AIF1 allograft inflammatory factor 1 -0.00535079
CAMP cathelicidin antimicrobial peptide -0.00534554
MAOA monoamine oxidase A -0.00532783
GLS glutaminase -0.00532674
TSPO translocator protein (18kDa) -0.00531955
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.005288
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00528678
FPR1 formyl peptide receptor 1 -0.00522764
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00522106
CCL13 chemokine (C-C motif) ligand 13 -0.00521719
C2 complement component 2 -0.00520296
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0051965
SNAI2 snail family zinc finger 2 -0.00519048
EFHC2 EF-hand domain (C-terminal) containing 2 -0.00514709
SIKE1 suppressor of IKBKE 1 -0.00512539
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00511802
FOLR2 folate receptor 2 (fetal) -0.00509734
GLUL glutamate-ammonia ligase -0.00509621
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00506762
FBLN2 fibulin 2 -0.0050629
FBLN1 fibulin 1 -0.00506163
KIAA0513 KIAA0513 -0.00504579
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.0050452
COL1A2 collagen, type I, alpha 2 -0.005041
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00503521
CCR1 chemokine (C-C motif) receptor 1 -0.00503066
MANSC1 MANSC domain containing 1 -0.00502664
UGDH UDP-glucose 6-dehydrogenase -0.00501934
REEP1 receptor accessory protein 1 -0.00501501
VSIG4 V-set and immunoglobulin domain containing 4 -0.00501252
ABAT 4-aminobutyrate aminotransferase -0.00498388
ALOX5 arachidonate 5-lipoxygenase -0.00498094
S100A4 S100 calcium binding protein A4 -0.00497823
ELOVL5 ELOVL fatty acid elongase 5 -0.00497776
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00497304
CCL4 chemokine (C-C motif) ligand 4 -0.00496099
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.00495805
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -0.0049446
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00494167
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00493789
LYZ lysozyme -0.0049372
FPR3 formyl peptide receptor 3 -0.00492976
TMEM176A transmembrane protein 176A -0.0049124
CCL8 chemokine (C-C motif) ligand 8 -0.00490487
S100A6 S100 calcium binding protein A6 -0.00487705
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -0.00487269
TTC38 tetratricopeptide repeat domain 38 -0.00485606
NCAM1 neural cell adhesion molecule 1 -0.00484492
NINJ2 ninjurin 2 -0.00483538
WASL Wiskott-Aldrich syndrome-like -0.00483026
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00481873
TIPRL TOR signaling pathway regulator -0.00481655
FRZB frizzled-related protein -0.00480326
HPGDS hematopoietic prostaglandin D synthase -0.00479954
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.00479674
ZNF423 zinc finger protein 423 -0.00479581
PRKCB protein kinase C, beta -0.00479363
ANGPT1 angiopoietin 1 -0.00479314
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00478705
FABP1 fatty acid binding protein 1, liver -0.00477153
TPST2 tyrosylprotein sulfotransferase 2 -0.00476716
CLGN calmegin -0.00474256
MLPH melanophilin -0.0047334
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.0047171
CD58 CD58 molecule -0.00471377
ST18 suppression of tumorigenicity 18, zinc finger -0.0047123
TPD52 tumor protein D52 -0.00465509
SMC1A structural maintenance of chromosomes 1A -0.00465231
CLEC7A C-type lectin domain family 7, member A -0.00463471
AKR1C3 aldo-keto reductase family 1, member C3 -0.00463155
RTN1 reticulon 1 -0.0046075
ACKR3 atypical chemokine receptor 3 -0.00460218
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00458638
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.0045813
AGR2 anterior gradient 2 -0.0045738
VCAM1 vascular cell adhesion molecule 1 -0.00457218
RNASE6 ribonuclease, RNase A family, k6 -0.0045583
HSPA2 heat shock 70kDa protein 2 -0.00454699
TGFBI transforming growth factor, beta-induced, 68kDa -0.00453275
KRT19 keratin 19, type I -0.00452948
COL3A1 collagen, type III, alpha 1 -0.00452858
LRRC15 leucine rich repeat containing 15 -0.0045269
SMYD3 SET and MYND domain containing 3 -0.00452517
ARG1 arginase 1 -0.00452083
CLDN3 claudin 3 -0.00450062
PDZRN3 PDZ domain containing ring finger 3 -0.00449702
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00448086
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00447357
AZF1 azoospermia factor 1 -0.00447115
APMAP adipocyte plasma membrane associated protein -0.0044706
SPARCL1 SPARC-like 1 (hevin) -0.00446991
TNC tenascin C -0.00446476
ANXA4 annexin A4 -0.00446188
GLRX2 glutaredoxin 2 -0.00446159
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00445175
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -0.00444995
RAP2A RAP2A, member of RAS oncogene family -0.00444382
TMEM106B transmembrane protein 106B -0.00443474
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00443393
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00440983
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -0.00437974
AQP1 aquaporin 1 (Colton blood group) -0.00436077
IFITM1 interferon induced transmembrane protein 1 -0.00434757
BCHE butyrylcholinesterase -0.00433538
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00433351
CPVL carboxypeptidase, vitellogenic-like -0.00432456
SEPHS2 selenophosphate synthetase 2 -0.00430659
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00429834
COL6A2 collagen, type VI, alpha 2 -0.00429151
AUTS2 autism susceptibility candidate 2 -0.00428861
CCL20 chemokine (C-C motif) ligand 20 -0.00428453
COCH cochlin -0.0042697
SRPX sushi-repeat containing protein, X-linked -0.00426949
DCT dopachrome tautomerase -0.00426053
AHNAK2 AHNAK nucleoprotein 2 -0.00425812
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00425689
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00425274
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0042524
CD209 CD209 molecule -0.00420123
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -0.00419512
WSB1 WD repeat and SOCS box containing 1 -0.00419353
F3 coagulation factor III (thromboplastin, tissue factor) -0.00419277
SCARB2 scavenger receptor class B, member 2 -0.00417117
HTRA1 HtrA serine peptidase 1 -0.00417014
DSP desmoplakin -0.00416836
RNF115 ring finger protein 115 -0.00416499
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00416344
SLA Src-like-adaptor -0.00416267
GCLC glutamate-cysteine ligase, catalytic subunit -0.00415593
GOLIM4 golgi integral membrane protein 4 -0.00415079
DEPTOR DEP domain containing MTOR-interacting protein -0.00414872
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.0041465
BCL7B B-cell CLL/lymphoma 7B -0.00414446
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00413872
PLEK pleckstrin -0.00413409
GPM6A glycoprotein M6A -0.00411655
RTN2 reticulon 2 -0.00411232
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.0041121
RTN3 reticulon 3 -0.00410774