| Dataset | DGIdb Drug Targets 2026 |
| Category | physical interactions |
| Type | drug |
| Description | Thrombin is a trypsin-like serine protease protein that in humans is encoded by the F2 gene.[2][3] Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. (Experimental Factor Ontology, EFO_0003183) |
| External Link | https://dgidb.org/results?searchType=drug&searchTerms=THROMBIN |
| Similar Terms | |
| Downloads & Tools |
3 interacting proteins for the THROMBIN drug from theDGIdb Drug Targets 2026 dataset.
