| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | toll-like receptor adaptor molecule 1|This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 148022) |
| External Link | https://ncbi.nlm.nih.gov/gene/148022 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the TICAM1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.0101023 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00929333 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0085792 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00827716 |
| XIC | X chromosome inactivation center | 0.00827129 |
| TCF4 | transcription factor 4 | 0.00803585 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00779309 |
| TMSB15A | thymosin beta 15a | 0.00777836 |
| DACH1 | dachshund family transcription factor 1 | 0.00763177 |
| PRDX2 | peroxiredoxin 2 | 0.00759296 |
| METTL7A | methyltransferase like 7A | 0.00742618 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00738826 |
| ASRGL1 | asparaginase like 1 | 0.00731293 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00706615 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00692621 |
| PLAT | plasminogen activator, tissue | 0.00685031 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00680743 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00673277 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00666074 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0066538 |
| CEP170 | centrosomal protein 170kDa | 0.00657763 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00656908 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.0063057 |
| HMGB3 | high mobility group box 3 | 0.00624928 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00621413 |
| PKM | pyruvate kinase, muscle | 0.00618827 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00617038 |
| EMX2 | empty spiracles homeobox 2 | 0.0061535 |
| FASN | fatty acid synthase | 0.00614954 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00610367 |
| EREG | epiregulin | 0.00609405 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00609119 |
| DCK | deoxycytidine kinase | 0.0060036 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00591512 |
| TSPAN6 | tetraspanin 6 | 0.00579479 |
| KIF14 | kinesin family member 14 | 0.00578991 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00571505 |
| TKTL1 | transketolase-like 1 | 0.00571232 |
| FZD2 | frizzled class receptor 2 | 0.00570084 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00564974 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00562237 |
| CD9 | CD9 molecule | 0.00559713 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00557766 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00557239 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00556708 |
| HMGB1 | high mobility group box 1 | 0.00554576 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00553655 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00552903 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00540479 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00539705 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00538307 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00531016 |
| VEZF1 | vascular endothelial zinc finger 1 | 0.00530885 |
| PAX5 | paired box 5 | 0.00529723 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00526641 |
| USP1 | ubiquitin specific peptidase 1 | 0.0052555 |
| FBLN1 | fibulin 1 | 0.00525524 |
| CTBP2 | C-terminal binding protein 2 | 0.00522882 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00521998 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.005188 |
| DES | desmin | 0.00514047 |
| BCHE | butyrylcholinesterase | 0.00513101 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.00512101 |
| CD320 | CD320 molecule | 0.00509293 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.00508662 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00508016 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00507351 |
| CRIP2 | cysteine-rich protein 2 | 0.00507079 |
| TMEM109 | transmembrane protein 109 | 0.00506286 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00505919 |
| LPXN | leupaxin | 0.00504852 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00504536 |
| CYTL1 | cytokine-like 1 | 0.00503779 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.005034 |
| PGD | phosphogluconate dehydrogenase | 0.00502925 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00501908 |
| FBN2 | fibrillin 2 | 0.0050178 |
| TUBA1A | tubulin, alpha 1a | 0.00500421 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00498592 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00496817 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00496755 |
| CALR | calreticulin | 0.00495578 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00495078 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00493677 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00493399 |
| PRKCB | protein kinase C, beta | 0.00492227 |
| FADS1 | fatty acid desaturase 1 | 0.0049173 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00487984 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00486703 |
| LRRC17 | leucine rich repeat containing 17 | 0.0048645 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00485708 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 0.00478901 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00478137 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00478109 |
| SELENBP1 | selenium binding protein 1 | 0.00477903 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00477236 |
| HDGFL3 | HDGF like 3 | 0.00477164 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00476632 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00476565 |
| CENPX | centromere protein X | 0.00476256 |
| S100A4 | S100 calcium binding protein A4 | 0.00475024 |
| LBR | lamin B receptor | 0.00474877 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00474553 |
| ECT2 | epithelial cell transforming 2 | 0.00473731 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00473472 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00472281 |
| GAS1 | growth arrest-specific 1 | 0.00472028 |
| FAM111A | family with sequence similarity 111, member A | 0.00471119 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00471001 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.00466716 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00466599 |
| AUTS2 | autism susceptibility candidate 2 | 0.00464267 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00464107 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00463963 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00462916 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00458252 |
| NOTCH2 | notch 2 | 0.00458252 |
| CTSH | cathepsin H | 0.00456818 |
| GGCT | gamma-glutamylcyclotransferase | 0.00455509 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00454251 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.0045401 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00453866 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00452432 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.00451271 |
| SEPTIN7 | septin 7 | 0.00449763 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00448597 |
| MALT1 | MALT1 paracaspase | 0.00446108 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00445512 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.004454 |
| S100A2 | S100 calcium binding protein A2 | 0.004453 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00444509 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00444303 |
| SACS | sacsin molecular chaperone | 0.00444129 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 0.00444101 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00443988 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00443655 |
| EFNA4 | ephrin-A4 | 0.00442411 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00441168 |
| RMI1 | RecQ mediated genome instability 1 | 0.00439728 |
| HDAC2 | histone deacetylase 2 | 0.00439595 |
| TNS1 | tensin 1 | 0.00438188 |
| TOB1 | transducer of ERBB2, 1 | 0.00437524 |
| CCNF | cyclin F | 0.00433075 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00432418 |
| TBCD | tubulin folding cofactor D | 0.00431947 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00431944 |
| NMU | neuromedin U | 0.0043163 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00431467 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00431453 |
| CES1 | carboxylesterase 1 | 0.0043143 |
| LIN28A | lin-28 homolog A (C. elegans) | 0.00431315 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00430554 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.004303 |
| THBS4 | thrombospondin 4 | 0.00428956 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00428868 |
| IPO9 | importin 9 | 0.00428606 |
| PGC | progastricsin (pepsinogen C) | 0.00428262 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00428075 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.0042345 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00423354 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00423127 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00422357 |
| LRRC40 | leucine rich repeat containing 40 | 0.00422273 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0042183 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00421514 |
| FBXO5 | F-box protein 5 | 0.00421475 |
| VCAN | versican | 0.00421457 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 0.00421073 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.0042029 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.00419826 |
| SLC2A4RG | SLC2A4 regulator | 0.00419759 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0041937 |
| HOXC6 | homeobox C6 | 0.00419207 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | 0.00418354 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00418009 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00417201 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00416695 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00416623 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00416512 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00415763 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00414611 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00413559 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.00413471 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00412557 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00410103 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.0040946 |
| SEPTIN6 | septin 6 | 0.00408259 |
| TRMT5 | tRNA methyltransferase 5 | 0.00406994 |
| CRYM | crystallin, mu | 0.00406576 |
| LY86 | lymphocyte antigen 86 | 0.00405545 |
| DBF4 | DBF4 zinc finger | 0.00405281 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00404431 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0040254 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00400958 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00400131 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00399028 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.0039858 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | 0.00398187 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00397994 |
| MAGED1 | melanoma antigen family D1 | 0.0039755 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.00397415 |
| SALL1 | spalt-like transcription factor 1 | 0.00397249 |
| ANXA5 | annexin A5 | 0.00397172 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.00396814 |
| FAAH | fatty acid amide hydrolase | 0.00396749 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00395809 |
| NREP | neuronal regeneration related protein | 0.00395287 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.00394266 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00392962 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0039284 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00392618 |
| STMN1 | stathmin 1 | 0.00392238 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00391873 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00390416 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00390253 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00386809 |
| ZNF22 | zinc finger protein 22 | 0.00386668 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) | 0.00385155 |
| ESR1 | estrogen receptor 1 | 0.00384421 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.00384038 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00383729 |
| IDE | insulin-degrading enzyme | 0.0038358 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00383275 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00383176 |
| CTSC | cathepsin C | 0.00383158 |
| DIAPH2 | diaphanous-related formin 2 | 0.00382701 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.00382699 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00381981 |
| NANOG | Nanog homeobox | 0.00381692 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00381353 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00380363 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00379502 |
| CDK1 | cyclin-dependent kinase 1 | 0.00379231 |
| MAOA | monoamine oxidase A | 0.00378843 |
| H2AZ1 | H2A.Z variant histone 1 | 0.00377554 |
| HYOU1 | hypoxia up-regulated 1 | 0.00377506 |
| MECOM | MDS1 and EVI1 complex locus | 0.00376327 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00375875 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00374583 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00374562 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00373995 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00373819 |
| MUC4 | mucin 4, cell surface associated | 0.00373608 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00373129 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00372134 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00372093 |
| OIP5 | Opa interacting protein 5 | 0.00372047 |
| CENPF | centromere protein F, 350/400kDa | 0.0037204 |
| EFNB2 | ephrin-B2 | 0.00371186 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00371089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0113225 |
| ATF3 | activating transcription factor 3 | -0.0112551 |
| ADM | adrenomedullin | -0.0110183 |
| CCN2 | cellular communication network factor 2 | -0.0101735 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00973614 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00931901 |
| DSP | desmoplakin | -0.00851886 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.0080836 |
| LXN | latexin | -0.00805181 |
| RGCC | regulator of cell cycle | -0.0080199 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00794947 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00776512 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00776083 |
| ASS1 | argininosuccinate synthase 1 | -0.00775436 |
| KRT14 | keratin 14, type I | -0.0076923 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00765673 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00763019 |
| CRYAB | crystallin, alpha B | -0.00752952 |
| ANXA4 | annexin A4 | -0.0074502 |
| GATA6 | GATA binding protein 6 | -0.00743614 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0073961 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00735988 |
| MT1X | metallothionein 1X | -0.0073041 |
| RBM34 | RNA binding motif protein 34 | -0.00726454 |
| CAST | calpastatin | -0.00720426 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00719702 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00710086 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00710049 |
| ZFP36 | ZFP36 ring finger protein | -0.00701444 |
| SNAI2 | snail family zinc finger 2 | -0.00698716 |
| MYOF | myoferlin | -0.00696773 |
| KRT81 | keratin 81, type II | -0.00689329 |
| S100A8 | S100 calcium binding protein A8 | -0.00684516 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00675436 |
| TRIM29 | tripartite motif containing 29 | -0.00670036 |
| ANXA1 | annexin A1 | -0.00668352 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00665359 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00660199 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00659755 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0065856 |
| EGR1 | early growth response 1 | -0.00652228 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00649441 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00631165 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | -0.00626243 |
| PSAP | prosaposin | -0.00625492 |
| CD14 | CD14 molecule | -0.00621057 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00616145 |
| NRCAM | neuronal cell adhesion molecule | -0.00607199 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00605741 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00605511 |
| S100A9 | S100 calcium binding protein A9 | -0.00601079 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00599407 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00598601 |
| MAP7 | microtubule-associated protein 7 | -0.00596929 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00594571 |
| OPTN | optineurin | -0.00586495 |
| TPD52 | tumor protein D52 | -0.00580997 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00580173 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00579884 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00577716 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00573244 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00570858 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00569937 |
| AOC1 | amine oxidase, copper containing 1 | -0.00569791 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00568215 |
| MARCO | macrophage receptor with collagenous structure | -0.00568135 |
| DIPK1A | divergent protein kinase domain 1A | -0.00567623 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00562501 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | -0.00561824 |
| BAG3 | BCL2-associated athanogene 3 | -0.00561624 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00560188 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00558667 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00558332 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00552814 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00552106 |
| OLFML2A | olfactomedin-like 2A | -0.00551308 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00550644 |
| CA2 | carbonic anhydrase II | -0.00549542 |
| EDN1 | endothelin 1 | -0.00548867 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00547204 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00546739 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00545785 |
| RND3 | Rho family GTPase 3 | -0.00545731 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0054283 |
| RHOB | ras homolog family member B | -0.0054216 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00540388 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00540284 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00539858 |
| ITGB4 | integrin, beta 4 | -0.00535715 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00532718 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00531026 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00529945 |
| FNTA | farnesyltransferase, CAAX box, alpha | -0.0052938 |
| RIOK3 | RIO kinase 3 | -0.00527947 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.005271 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00524966 |
| CD163 | CD163 molecule | -0.00523968 |
| TUFT1 | tuftelin 1 | -0.00519695 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00518721 |
| TFF2 | trefoil factor 2 | -0.00516743 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00515388 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00514669 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00514643 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00514518 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00512357 |
| A2M | alpha-2-macroglobulin | -0.0050928 |
| KRT23 | keratin 23, type I | -0.00509274 |
| NRN1 | neuritin 1 | -0.00508351 |
| KLK5 | kallikrein-related peptidase 5 | -0.005074 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00502077 |
| S100P | S100 calcium binding protein P | -0.00500977 |
| NDRG1 | N-myc downstream regulated 1 | -0.00500693 |
| NOTCH1 | notch 1 | -0.00500149 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00499116 |
| BMP2 | bone morphogenetic protein 2 | -0.00496925 |
| NXN | nucleoredoxin | -0.00496507 |
| GSDMB | gasdermin B | -0.00496038 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.00491884 |
| GAS2 | growth arrest-specific 2 | -0.00488945 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00486329 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00483892 |
| CTSD | cathepsin D | -0.00483753 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00483266 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00483074 |
| ABLIM1 | actin binding LIM protein 1 | -0.00481059 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00479097 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00478988 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00478833 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0047813 |
| GSTZ1 | glutathione S-transferase zeta 1 | -0.00476836 |
| PXDC1 | PX domain containing 1 | -0.00476008 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00472132 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00472001 |
| TXNIP | thioredoxin interacting protein | -0.00471651 |
| KLK10 | kallikrein-related peptidase 10 | -0.00471229 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00470825 |
| FCGBP | Fc fragment of IgG binding protein | -0.00470717 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00468086 |
| CCNA2 | cyclin A2 | -0.00466229 |
| FOXC1 | forkhead box C1 | -0.00465486 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00465062 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -0.00463398 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00460023 |
| OLFML2B | olfactomedin-like 2B | -0.00459306 |
| VNN1 | vanin 1 | -0.0045741 |
| KRT16 | keratin 16, type I | -0.00456041 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00455298 |
| EFHD1 | EF-hand domain family, member D1 | -0.0045517 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00454589 |
| ANGPTL2 | angiopoietin-like 2 | -0.00453324 |
| EGR2 | early growth response 2 | -0.00452809 |
| HNMT | histamine N-methyltransferase | -0.00450825 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00450762 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0044822 |
| KRT6A | keratin 6A, type II | -0.00448207 |
| OAT | ornithine aminotransferase | -0.00447779 |
| AMOTL2 | angiomotin like 2 | -0.00447028 |
| FILIP1L | filamin A interacting protein 1-like | -0.00446851 |
| GPX3 | glutathione peroxidase 3 | -0.00446479 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00445851 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00444987 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00444698 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.00443968 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00443202 |
| EPS8L2 | EPS8-like 2 | -0.00442829 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00442605 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00441756 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00440791 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00439749 |
| LPIN1 | lipin 1 | -0.00438311 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00437239 |
| TRIM16 | tripartite motif containing 16 | -0.00436518 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00436214 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00435986 |
| RTCA | RNA 3'-terminal phosphate cyclase | -0.00435676 |
| CTSS | cathepsin S | -0.00435498 |
| ANXA10 | annexin A10 | -0.00435241 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00434898 |
| FHL2 | four and a half LIM domains 2 | -0.00434215 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00433318 |
| CHGB | chromogranin B | -0.00432745 |
| ADA | adenosine deaminase | -0.00431539 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00431312 |
| MIA | melanoma inhibitory activity | -0.00431291 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00430418 |
| PERP | PERP, TP53 apoptosis effector | -0.00429983 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0042984 |
| UBE3C | ubiquitin protein ligase E3C | -0.00429801 |
| PLCL1 | phospholipase C-like 1 | -0.00429409 |
| KLF2 | Kruppel-like factor 2 | -0.00428402 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00427249 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00426679 |
| KLF9 | Kruppel-like factor 9 | -0.00425064 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00423572 |
| MT1F | metallothionein 1F | -0.00421694 |
| AVPI1 | arginine vasopressin-induced 1 | -0.00419451 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00419447 |
| RGS2 | regulator of G-protein signaling 2 | -0.00418439 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00417512 |
| ATF4 | activating transcription factor 4 | -0.00417231 |
| RAI14 | retinoic acid induced 14 | -0.0041698 |
| CTSE | cathepsin E | -0.00416256 |
| ATP9A | ATPase, class II, type 9A | -0.00415677 |
| LRRC1 | leucine rich repeat containing 1 | -0.00415442 |
| RNF103 | ring finger protein 103 | -0.00415374 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.00414494 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00413917 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00413534 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0041334 |
| TFF1 | trefoil factor 1 | -0.00413154 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00412106 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00411949 |
| PNMA8A | PNMA family member 8A | -0.00411649 |
| MMP9 | matrix metallopeptidase 9 | -0.00411229 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.00409506 |
| INSR | insulin receptor | -0.0040924 |
| CHMP3 | charged multivesicular body protein 3 | -0.00409064 |
| LAX1 | lymphocyte transmembrane adaptor 1 | -0.00408898 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00408619 |
| ARL14 | ADP-ribosylation factor-like 14 | -0.00407191 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00406862 |
| TMEM140 | transmembrane protein 140 | -0.00406682 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00406314 |
| TGFB1 | transforming growth factor, beta 1 | -0.00405768 |
| CDV3 | CDV3 homolog (mouse) | -0.00405488 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00405259 |
| TESC | tescalcin | -0.00405219 |
| RGS3 | regulator of G-protein signaling 3 | -0.00404373 |
| COL2A1 | collagen, type II, alpha 1 | -0.00402651 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00401583 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.00401125 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0040052 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00400505 |
| MT2A | metallothionein 2A | -0.00400474 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00399692 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0039941 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00397786 |
| OXTR | oxytocin receptor | -0.00397759 |
| JUNB | jun B proto-oncogene | -0.00397517 |
| C3AR1 | complement component 3a receptor 1 | -0.00397042 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00396755 |
| IL18 | interleukin 18 | -0.0039561 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.00395159 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0039447 |
| GPR137B | G protein-coupled receptor 137B | -0.00394348 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.00393393 |
| PDGFC | platelet derived growth factor C | -0.00391373 |
| UST | uronyl-2-sulfotransferase | -0.00391147 |
| KLF6 | Kruppel-like factor 6 | -0.00390896 |
| NTS | neurotensin | -0.00390636 |
