| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | tyrosine kinase with immunoglobulin-like and EGF-like domains 1|This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 7075) |
| External Link | https://ncbi.nlm.nih.gov/gene/7075 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the TIE1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0171563 |
| S100A9 | S100 calcium binding protein A9 | 0.0150763 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0133719 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0128808 |
| HOPX | HOP homeobox | 0.0127383 |
| S100A7 | S100 calcium binding protein A7 | 0.0117881 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0112544 |
| NPR3 | natriuretic peptide receptor 3 | 0.01118 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.0109139 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.0106431 |
| BCHE | butyrylcholinesterase | 0.0105264 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0105187 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0105118 |
| WDR61 | WD repeat domain 61 | 0.00979788 |
| GLO1 | glyoxalase I | 0.00962599 |
| NREP | neuronal regeneration related protein | 0.00942337 |
| SATB2 | SATB homeobox 2 | 0.00932774 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00930336 |
| RPS5 | ribosomal protein S5 | 0.00924135 |
| S100A8 | S100 calcium binding protein A8 | 0.00922929 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00907708 |
| KRT1 | keratin 1, type II | 0.00905055 |
| CDC42 | cell division cycle 42 | 0.00898359 |
| HOXB7 | homeobox B7 | 0.00898065 |
| CA12 | carbonic anhydrase XII | 0.00885537 |
| CCNA2 | cyclin A2 | 0.00872585 |
| ADORA2B | adenosine A2b receptor | 0.00870228 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00864477 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00862795 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00859604 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00855114 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00830307 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.0082601 |
| MAGEA3 | melanoma antigen family A3 | 0.00825583 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00824842 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00811161 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.00809923 |
| S100A12 | S100 calcium binding protein A12 | 0.00803637 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00787038 |
| SPRR1B | small proline-rich protein 1B | 0.00776782 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00773367 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00772162 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00767011 |
| SRP72 | signal recognition particle 72kDa | 0.00766778 |
| MALL | mal, T-cell differentiation protein-like | 0.00765871 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00765109 |
| MDFIC | MyoD family inhibitor domain containing | 0.00761784 |
| COMMD10 | COMM domain containing 10 | 0.00755705 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00753016 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00752395 |
| SELL | selectin L | 0.00747106 |
| TCTA | T-cell leukemia translocation altered | 0.00743597 |
| CRYL1 | crystallin, lambda 1 | 0.00738645 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00734976 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00728987 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00726515 |
| KRT10 | keratin 10, type I | 0.0071726 |
| TCF21 | transcription factor 21 | 0.00716311 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00714546 |
| FASN | fatty acid synthase | 0.00714019 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00713867 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00713017 |
| HLTF | helicase-like transcription factor | 0.00712999 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00711174 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00708709 |
| TPM4 | tropomyosin 4 | 0.00707696 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00699362 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0069923 |
| PLBD1 | phospholipase B domain containing 1 | 0.00698532 |
| SFTPD | surfactant protein D | 0.00698293 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00691634 |
| TSPAN6 | tetraspanin 6 | 0.00688834 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00685491 |
| PITX3 | paired-like homeodomain 3 | 0.00685014 |
| TYRP1 | tyrosinase-related protein 1 | 0.00684802 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00680158 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00679294 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00679234 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.006768 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00676659 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00676619 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00675775 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00675219 |
| PRDX4 | peroxiredoxin 4 | 0.00673439 |
| MFF | mitochondrial fission factor | 0.00671759 |
| RNF14 | ring finger protein 14 | 0.00671128 |
| AQP4 | aquaporin 4 | 0.00668636 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.00667903 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00662311 |
| F2R | coagulation factor II (thrombin) receptor | 0.00660359 |
| TSPAN13 | tetraspanin 13 | 0.00658903 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00655744 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00655062 |
| TMEM168 | transmembrane protein 168 | 0.00651498 |
| CDC42SE1 | CDC42 small effector 1 | 0.00650638 |
| GMFB | glia maturation factor, beta | 0.00649457 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00647535 |
| UBL3 | ubiquitin-like 3 | 0.00647307 |
| HOXB6 | homeobox B6 | 0.00647178 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00646864 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00642258 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00642199 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00641663 |
| DCP2 | decapping mRNA 2 | 0.00641639 |
| AK4 | adenylate kinase 4 | 0.00641159 |
| SUCLG1 | succinate-CoA ligase, alpha subunit | 0.00639083 |
| HAS2 | hyaluronan synthase 2 | 0.00639039 |
| HIST3H2A | histone cluster 3, H2a | 0.00634927 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 0.00630178 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00625021 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00624376 |
| KIF23 | kinesin family member 23 | 0.00621981 |
| HNMT | histamine N-methyltransferase | 0.00621894 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00620903 |
| RXRA | retinoid X receptor, alpha | 0.00619131 |
| ABHD10 | abhydrolase domain containing 10 | 0.00617641 |
| COLEC12 | collectin sub-family member 12 | 0.00617156 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00617004 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00616049 |
| SFTPC | surfactant protein C | 0.00615628 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.0061463 |
| SPRR2B | small proline-rich protein 2B | 0.00610822 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | 0.00608494 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00608421 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00608018 |
| RGS10 | regulator of G-protein signaling 10 | 0.00605357 |
| DCK | deoxycytidine kinase | 0.00604781 |
| ESD | esterase D | 0.00602969 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00602238 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.006011 |
| TMEM38B | transmembrane protein 38B | 0.00600552 |
| SEPTIN11 | septin 11 | 0.0059943 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00598228 |
| C5ORF28 | chromosome 5 open reading frame 28 | 0.00596049 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00592467 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00590689 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.00590672 |
| MREG | melanoregulin | 0.00590518 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00589814 |
| RNF130 | ring finger protein 130 | 0.00589446 |
| KIF20A | kinesin family member 20A | 0.00589284 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00587933 |
| RPIA | ribose 5-phosphate isomerase A | 0.00587852 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.0058697 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.00586327 |
| AOC1 | amine oxidase, copper containing 1 | 0.00585007 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00584119 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00584022 |
| TIPRL | TOR signaling pathway regulator | 0.00583634 |
| FASTKD3 | FAST kinase domains 3 | 0.0058329 |
| MEIS2 | Meis homeobox 2 | 0.00582618 |
| FZD5 | frizzled class receptor 5 | 0.00582123 |
| RIOX2 | ribosomal oxygenase 2 | 0.00579577 |
| GLRX5 | glutaredoxin 5 | 0.00579015 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00578833 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00578562 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00577753 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00577345 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.00575334 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00574633 |
| DAPK1 | death-associated protein kinase 1 | 0.00572242 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0057217 |
| SET | SET nuclear proto-oncogene | 0.00571672 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.0057116 |
| TEX30 | testis expressed 30 | 0.00570703 |
| FOXF1 | forkhead box F1 | 0.00568425 |
| HOXA5 | homeobox A5 | 0.00566997 |
| RHCG | Rh family, C glycoprotein | 0.00566276 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00566204 |
| SRP9 | signal recognition particle 9kDa | 0.00564594 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00563273 |
| CST3 | cystatin C | 0.00562871 |
| NDNF | neuron-derived neurotrophic factor | 0.00561763 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00559688 |
| HPCAL1 | hippocalcin-like 1 | 0.00559334 |
| THOC7 | THO complex 7 | 0.00558522 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.0055814 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00557612 |
| COMMD8 | COMM domain containing 8 | 0.00554553 |
| DMXL1 | Dmx-like 1 | 0.00554107 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00553044 |
| SFXN1 | sideroflexin 1 | 0.00552978 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00551396 |
| S100A2 | S100 calcium binding protein A2 | 0.00551284 |
| CD48 | CD48 molecule | 0.00550254 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00550209 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00550025 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00549631 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00549242 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 0.00548699 |
| ACTL6A | actin-like 6A | 0.00546213 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00545957 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00545043 |
| IFT57 | intraflagellar transport 57 | 0.00544958 |
| ADCY7 | adenylate cyclase 7 | 0.00544923 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00543595 |
| SELENOT | selenoprotein T | 0.00543208 |
| NOL11 | nucleolar protein 11 | 0.00543036 |
| DHPS | deoxyhypusine synthase | 0.00541595 |
| CRIP2 | cysteine-rich protein 2 | 0.00541582 |
| FBXW2 | F-box and WD repeat domain containing 2 | 0.00541546 |
| DHFR | dihydrofolate reductase | 0.00540564 |
| TRIB2 | tribbles pseudokinase 2 | 0.00538318 |
| ENOSF1 | enolase superfamily member 1 | 0.00537099 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00536335 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 0.00536293 |
| E2F8 | E2F transcription factor 8 | 0.0053419 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00533256 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00532931 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00532282 |
| EDNRB | endothelin receptor type B | 0.00531922 |
| COPS2 | COP9 signalosome subunit 2 | 0.00531683 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | 0.00531011 |
| NEK7 | NIMA-related kinase 7 | 0.00530409 |
| LBR | lamin B receptor | 0.00530129 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00529027 |
| CTSH | cathepsin H | 0.0052878 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00528145 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00528089 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00527319 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.00527009 |
| THAP12 | THAP domain containing 12 | 0.00526765 |
| TLK2 | tousled-like kinase 2 | 0.00526056 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00525805 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 0.00524972 |
| UBE2N | ubiquitin-conjugating enzyme E2N | 0.00524813 |
| RAB25 | RAB25, member RAS oncogene family | 0.0052409 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 | 0.00523994 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.00523423 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00523325 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | 0.0052296 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00522801 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00522057 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.00521313 |
| LMNB1 | lamin B1 | 0.00520572 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00520215 |
| WT1 | Wilms tumor 1 | 0.00518984 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00517429 |
| SFN | stratifin | 0.00516434 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00515134 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0051507 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase | 0.00514863 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00514851 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.00514781 |
| CDK1 | cyclin-dependent kinase 1 | 0.00514618 |
| CEP55 | centrosomal protein 55kDa | 0.00514369 |
| ZNF124 | zinc finger protein 124 | 0.00513809 |
| PPID | peptidylprolyl isomerase D | 0.00513742 |
| BAG2 | BCL2-associated athanogene 2 | 0.00513161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0197267 |
| XIC | X chromosome inactivation center | -0.0180366 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0170701 |
| CFB | complement factor B | -0.01647 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0161922 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0145646 |
| KRT23 | keratin 23, type I | -0.0142907 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0138895 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0129739 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0125114 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0124834 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0120374 |
| C3 | complement component 3 | -0.011932 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0117805 |
| MXRA5 | matrix-remodelling associated 5 | -0.0117346 |
| NAV2 | neuron navigator 2 | -0.0116087 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.0116028 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0115383 |
| ADIRF | adipogenesis regulatory factor | -0.0113671 |
| A2M | alpha-2-macroglobulin | -0.0113553 |
| RGS5 | regulator of G-protein signaling 5 | -0.0112558 |
| KRT15 | keratin 15, type I | -0.0111215 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0110851 |
| PEG3 | paternally expressed 3 | -0.011033 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.010823 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0108155 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0107218 |
| ADM | adrenomedullin | -0.0106467 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0105264 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.0104848 |
| RGCC | regulator of cell cycle | -0.0104613 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0104384 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.0104339 |
| FZD10 | frizzled class receptor 10 | -0.0103003 |
| SIK1 | salt-inducible kinase 1 | -0.0101964 |
| PLPP2 | phospholipid phosphatase 2 | -0.0101582 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0100526 |
| TSPAN8 | tetraspanin 8 | -0.0100199 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00999185 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00993292 |
| TAC1 | tachykinin, precursor 1 | -0.00992016 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00985184 |
| GPX2 | glutathione peroxidase 2 | -0.00981834 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00978202 |
| THBS2 | thrombospondin 2 | -0.00977185 |
| RTN2 | reticulon 2 | -0.00971466 |
| MMP3 | matrix metallopeptidase 3 | -0.00969639 |
| ALB | albumin | -0.00966916 |
| MMP7 | matrix metallopeptidase 7 | -0.00954429 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00952296 |
| PEG10 | paternally expressed 10 | -0.00952256 |
| MSMB | microseminoprotein, beta- | -0.00948242 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00943245 |
| PIP | prolactin-induced protein | -0.00942223 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00938585 |
| PXDC1 | PX domain containing 1 | -0.00937571 |
| CCN2 | cellular communication network factor 2 | -0.00937513 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00922207 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00922072 |
| TRIM29 | tripartite motif containing 29 | -0.00912095 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00909553 |
| PLLP | plasmolipin | -0.00905545 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00900479 |
| MXRA7 | matrix-remodelling associated 7 | -0.00900369 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00897642 |
| THBS4 | thrombospondin 4 | -0.00896658 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00895044 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00887122 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00884282 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00882412 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00879811 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00875941 |
| FILIP1L | filamin A interacting protein 1-like | -0.00871935 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00870532 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00858593 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0085787 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0085766 |
| LUM | lumican | -0.00856892 |
| ASPN | asporin | -0.00850578 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00846044 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00841762 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00840237 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00840054 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00837164 |
| ATF3 | activating transcription factor 3 | -0.00836324 |
| KRT18 | keratin 18, type I | -0.00834462 |
| RTN1 | reticulon 1 | -0.00833928 |
| OXTR | oxytocin receptor | -0.00830588 |
| MGLL | monoglyceride lipase | -0.0082983 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00824791 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00823978 |
| IRS2 | insulin receptor substrate 2 | -0.00821507 |
| G0S2 | G0/G1 switch 2 | -0.00818259 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00817347 |
| COMP | cartilage oligomeric matrix protein | -0.00817091 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00812224 |
| ABLIM1 | actin binding LIM protein 1 | -0.00811036 |
| VNN1 | vanin 1 | -0.00810788 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00810444 |
| TESC | tescalcin | -0.00808864 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00800761 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00795352 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00793163 |
| ASS1 | argininosuccinate synthase 1 | -0.00791635 |
| VGLL4 | vestigial-like family member 4 | -0.00790227 |
| BTG2 | BTG family, member 2 | -0.00789604 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00789467 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0078821 |
| SIRT3 | sirtuin 3 | -0.00788157 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00787849 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00787541 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00786555 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00784159 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00780455 |
| SYNM | synemin, intermediate filament protein | -0.00779966 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00776749 |
| FBLN2 | fibulin 2 | -0.00772479 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00768495 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00768194 |
| TGFA | transforming growth factor, alpha | -0.00764785 |
| IER5 | immediate early response 5 | -0.00763727 |
| MCAM | melanoma cell adhesion molecule | -0.00761623 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00760996 |
| TFF1 | trefoil factor 1 | -0.00759675 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00755933 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00755268 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00754306 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00754085 |
| CRYAB | crystallin, alpha B | -0.00753632 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00748329 |
| EPCAM | epithelial cell adhesion molecule | -0.00748059 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00747288 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00739973 |
| BMP2 | bone morphogenetic protein 2 | -0.00739104 |
| RET | ret proto-oncogene | -0.0073568 |
| SGCE | sarcoglycan, epsilon | -0.00730608 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00729458 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00727793 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00726918 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00724237 |
| SSPN | sarcospan | -0.00724057 |
| PALMD | palmdelphin | -0.007235 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0072207 |
| MFAP5 | microfibrillar associated protein 5 | -0.00721954 |
| ECM1 | extracellular matrix protein 1 | -0.00721155 |
| USP6NL | USP6 N-terminal like | -0.00717844 |
| VWF | von Willebrand factor | -0.00714613 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | -0.00712044 |
| HMOX1 | heme oxygenase 1 | -0.00711268 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00710665 |
| AHSG | alpha-2-HS-glycoprotein | -0.00707711 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00705881 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00704491 |
| RGS16 | regulator of G-protein signaling 16 | -0.0070369 |
| RUNX1 | runt-related transcription factor 1 | -0.00703101 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00703043 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00699687 |
| WDR45 | WD repeat domain 45 | -0.00695532 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00692776 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00690021 |
| DIPK1A | divergent protein kinase domain 1A | -0.0068987 |
| PSCA | prostate stem cell antigen | -0.00689608 |
| CES1 | carboxylesterase 1 | -0.00686576 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00680903 |
| ACAN | aggrecan | -0.00678332 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00677788 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00677056 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00674866 |
| COBL | cordon-bleu WH2 repeat protein | -0.00674678 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00674359 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00673555 |
| STX4 | syntaxin 4 | -0.0067179 |
| APOB | apolipoprotein B | -0.00668912 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00668142 |
| LBH | limb bud and heart development | -0.00667976 |
| AREG | amphiregulin | -0.00667053 |
| UROD | uroporphyrinogen decarboxylase | -0.00664154 |
| KRT14 | keratin 14, type I | -0.00663698 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00662395 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00661906 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.0066134 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00659587 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | -0.00659463 |
| TSPAN1 | tetraspanin 1 | -0.006592 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00656048 |
| TES | testin LIM domain protein | -0.00653238 |
| ZNF721 | zinc finger protein 721 | -0.00652744 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00648531 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.00648156 |
| LPIN2 | lipin 2 | -0.00641819 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00639818 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00638338 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00637583 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.006367 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -0.00636332 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00632684 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.00632503 |
| ZNF395 | zinc finger protein 395 | -0.00632473 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00632378 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00630311 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00629845 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.00626617 |
| FMOD | fibromodulin | -0.00622562 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.00621843 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.0062035 |
| PCDH9 | protocadherin 9 | -0.00619889 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00619756 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.0061822 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00616234 |
| S100P | S100 calcium binding protein P | -0.00610928 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00610833 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00608427 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00607593 |
| IRF6 | interferon regulatory factor 6 | -0.00606752 |
| INSR | insulin receptor | -0.00605392 |
| BLNK | B-cell linker | -0.00603566 |
| BEX4 | brain expressed, X-linked 4 | -0.00603183 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00602072 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00601449 |
| CPE | carboxypeptidase E | -0.00601278 |
| TBX3 | T-box 3 | -0.00600292 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00599056 |
| ACVR1 | activin A receptor, type I | -0.00597934 |
| SNAI2 | snail family zinc finger 2 | -0.00597892 |
| HMGA1 | high mobility group AT-hook 1 | -0.00595838 |
| ATP9A | ATPase, class II, type 9A | -0.00593836 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.00593229 |
| FGF13 | fibroblast growth factor 13 | -0.00592469 |
| DCLK1 | doublecortin-like kinase 1 | -0.00592145 |
| NEFM | neurofilament, medium polypeptide | -0.00592022 |
| PPIF | peptidylprolyl isomerase F | -0.00590336 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00589769 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00588638 |
| TG | thyroglobulin | -0.00588497 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.00586936 |
| EFNA1 | ephrin-A1 | -0.00586833 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00586104 |
| HIP1R | huntingtin interacting protein 1 related | -0.00584881 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.00583789 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00583713 |
| SLC35E3 | solute carrier family 35, member E3 | -0.00583455 |
| LDB3 | LIM domain binding 3 | -0.00582887 |
| PDE8B | phosphodiesterase 8B | -0.00582722 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00582721 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00581402 |
| EIF6 | eukaryotic translation initiation factor 6 | -0.00580669 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00578813 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -0.00577758 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00577738 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.0057713 |
