TIE1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description tyrosine kinase with immunoglobulin-like and EGF-like domains 1|This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 7075)
External Link http://www.ncbi.nlm.nih.gov/gene/7075
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Genes

1 substrates of the kinase TIE1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1