TIE1_knockdown_107_GSE27869 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27869
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Genes

600 genes differentially expressed following the TIE1_knockdown_107_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
TGOLN2 trans-golgi network protein 2 2.83849
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 2.77317
ZNF641 zinc finger protein 641 2.77087
ARPIN actin-related protein 2/3 complex inhibitor 2.73245
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 2.63216
EIF3D eukaryotic translation initiation factor 3, subunit D 2.52071
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.51404
SCAND2P SCAN domain containing 2 pseudogene 2.40123
EFNA2 ephrin-A2 2.39253
ULBP2 UL16 binding protein 2 2.38049
FAM187A family with sequence similarity 187, member A 2.35208
H2AFZ H2A histone family, member Z 2.34721
POU2F3 POU class 2 homeobox 3 2.32822
WDR77 WD repeat domain 77 2.29029
FAM204A family with sequence similarity 204, member A 2.28418
CASS4 Cas scaffolding protein family member 4 2.27371
PCBP1 poly(rC) binding protein 1 2.26872
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 2.26492
RPS16 ribosomal protein S16 2.25606
PELO pelota homolog (Drosophila) 2.24997
GGCX gamma-glutamyl carboxylase 2.24241
APOC4 apolipoprotein C-IV 2.23862
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.23608
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 2.21408
SULT4A1 sulfotransferase family 4A, member 1 2.18521
GADD45A growth arrest and DNA-damage-inducible, alpha 2.17945
UBE2K ubiquitin-conjugating enzyme E2K 2.17692
INTS6 integrator complex subunit 6 2.1697
CDH13 cadherin 13 2.15826
DENND3 DENN/MADD domain containing 3 2.15786
EMC8 ER membrane protein complex subunit 8 2.14034
NRSN2 neurensin 2 2.13622
LPIN1 lipin 1 2.12941
DYNLL1 dynein, light chain, LC8-type 1 2.12824
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.121
IFRD1 interferon-related developmental regulator 1 2.11791
AMOTL2 angiomotin like 2 2.11452
SLC30A7 solute carrier family 30 (zinc transporter), member 7 2.11243
C9ORF78 chromosome 9 open reading frame 78 2.10799
RAB8A RAB8A, member RAS oncogene family 2.09955
ANXA2 annexin A2 2.09125
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 2.08256
CREB3L2 cAMP responsive element binding protein 3-like 2 2.06728
ZNF555 zinc finger protein 555 2.06429
MSL1 male-specific lethal 1 homolog (Drosophila) 2.05286
S1PR3 sphingosine-1-phosphate receptor 3 2.04946
KLHL26 kelch-like family member 26 2.04827
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.04274
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2.0384
SPRR2C small proline-rich protein 2C (pseudogene) 2.03261
PUF60 poly-U binding splicing factor 60KDa 2.03224
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.03015
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 2.02996
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2.02438
POLG polymerase (DNA directed), gamma 2.02304
PNLIPRP2 pancreatic lipase-related protein 2 2.02168
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.0192
CD276 CD276 molecule 2.01743
CHD8 chromodomain helicase DNA binding protein 8 2.01695
MYO10 myosin X 2.00604
TERF2IP telomeric repeat binding factor 2, interacting protein 2.00564
MFSD5 major facilitator superfamily domain containing 5 2.00535
IFI27 interferon, alpha-inducible protein 27 2.00226
ZNF80 zinc finger protein 80 2.00138
RPL10A ribosomal protein L10a 2.00029
FAM136A family with sequence similarity 136, member A 1.99327
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.98831
DUSP15 dual specificity phosphatase 15 1.98748
UBTF upstream binding transcription factor, RNA polymerase I 1.98646
GOLGA3 golgin A3 1.98208
MPZL1 myelin protein zero-like 1 1.98003
PDPR pyruvate dehydrogenase phosphatase regulatory subunit 1.96437
BTBD6 BTB (POZ) domain containing 6 1.96184
RPL41 ribosomal protein L41 1.95825
KRTCAP2 keratinocyte associated protein 2 1.95822
ZBTB16 zinc finger and BTB domain containing 16 1.95476
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.94422
EIF3B eukaryotic translation initiation factor 3, subunit B 1.94371
KRTAP5-9 keratin associated protein 5-9 1.93464
MAEA macrophage erythroblast attacher 1.92939
EPHA1 EPH receptor A1 1.92673
PITX3 paired-like homeodomain 3 1.92425
CBWD5 COBW domain containing 5 1.92332
RITA1 RBPJ interacting and tubulin associated 1 1.9228
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.92067
NOD1 nucleotide-binding oligomerization domain containing 1 1.91384
RPL38 ribosomal protein L38 1.91376
TMEM25 transmembrane protein 25 1.91334
MED7 mediator complex subunit 7 1.89872
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 1.89128
HAUS7 HAUS augmin-like complex, subunit 7 1.88971
DCAF8 DDB1 and CUL4 associated factor 8 1.88949
FRMD5 FERM domain containing 5 1.88736
METTL13 methyltransferase like 13 1.88671
FRMD4A FERM domain containing 4A 1.88533
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1.87288
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.86923
RBM14 RNA binding motif protein 14 1.86735
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.86658
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.86582
ERCC3 excision repair cross-complementation group 3 1.86338
FGF20 fibroblast growth factor 20 1.86323
PRSS27 protease, serine 27 1.85673
CRLS1 cardiolipin synthase 1 1.85574
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 1.85523
FOXC2 forkhead box C2 1.85138
CSNK1E casein kinase 1, epsilon 1.85038
INF2 inverted formin, FH2 and WH2 domain containing 1.84979
RBM15B RNA binding motif protein 15B 1.84854
HAS3 hyaluronan synthase 3 1.84447
CLPTM1L CLPTM1-like 1.84291
INTS12 integrator complex subunit 12 1.84112
SPHK2 sphingosine kinase 2 1.84047
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.8349
PRKCA protein kinase C, alpha 1.82948
LSMEM1 leucine-rich single-pass membrane protein 1 1.82731
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.82466
RNASE4 ribonuclease, RNase A family, 4 1.82348
PTRH2 peptidyl-tRNA hydrolase 2 1.82331
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.82241
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.82044
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.81795
GNG7 guanine nucleotide binding protein (G protein), gamma 7 1.81431
RFK riboflavin kinase 1.81263
POGK pogo transposable element with KRAB domain 1.81215
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.81118
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 1.80974
USP36 ubiquitin specific peptidase 36 1.80925
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 1.80466
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 1.80182
RFX5 regulatory factor X, 5 (influences HLA class II expression) 1.79451
DPP3 dipeptidyl-peptidase 3 1.79396
TIPRL TOR signaling pathway regulator 1.78939
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 1.78768
FEV FEV (ETS oncogene family) 1.78658
NLRP2 NLR family, pyrin domain containing 2 1.78363
STK38 serine/threonine kinase 38 1.78285
PRPF38B pre-mRNA processing factor 38B 1.77656
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.77431
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1.77396
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 1.77182
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.77109
PIEZO2 piezo-type mechanosensitive ion channel component 2 1.76814
C14ORF1 chromosome 14 open reading frame 1 1.7631
COPS4 COP9 signalosome subunit 4 1.76259
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.762
KIAA0391 KIAA0391 1.75741
MFF mitochondrial fission factor 1.75653
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 1.75505
SRD5A3 steroid 5 alpha-reductase 3 1.75158
DRAM1 DNA-damage regulated autophagy modulator 1 1.75001
F8A1 coagulation factor VIII-associated 1 1.74741
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.7454
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.74464
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 1.74462
PRSS54 protease, serine, 54 1.74193
NOL8 nucleolar protein 8 1.74175
MROH9 maestro heat-like repeat family member 9 1.73853
MARK3 MAP/microtubule affinity-regulating kinase 3 1.73412
PAX8-AS1 PAX8 antisense RNA 1 1.73328
TNIP2 TNFAIP3 interacting protein 2 1.73301
SPATC1L spermatogenesis and centriole associated 1-like 1.73198
C19ORF24 chromosome 19 open reading frame 24 1.73015
DNAAF2 dynein, axonemal, assembly factor 2 1.72992
ZFHX3 zinc finger homeobox 3 1.72444
ATAD2B ATPase family, AAA domain containing 2B 1.71597
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 1.71562
RER1 retention in endoplasmic reticulum sorting receptor 1 1.71461
SEPT2 septin 2 1.71237
NFASC neurofascin 1.71199
PYCR1 pyrroline-5-carboxylate reductase 1 1.70952
RBM48 RNA binding motif protein 48 1.70186
ZNF3 zinc finger protein 3 1.70136
ABHD17C abhydrolase domain containing 17C 1.70029
BIN1 bridging integrator 1 1.70018
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 1.69648
TMEM185B transmembrane protein 185B 1.696
ERH enhancer of rudimentary homolog (Drosophila) 1.6946
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 1.69328
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 1.68926
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.68712
RAB32 RAB32, member RAS oncogene family 1.68551
ELP3 elongator acetyltransferase complex subunit 3 1.68466
NRIP2 nuclear receptor interacting protein 2 1.68315
PCYOX1 prenylcysteine oxidase 1 1.6823
PAGR1 PAXIP1 associated glutamate-rich protein 1 1.68084
IFI44 interferon-induced protein 44 1.68069
GDE1 glycerophosphodiester phosphodiesterase 1 1.68007
STYK1 serine/threonine/tyrosine kinase 1 1.67636
ZBTB14 zinc finger and BTB domain containing 14 1.67362
H3F3B H3 histone, family 3B (H3.3B) 1.67191
SOD1 superoxide dismutase 1, soluble 1.67144
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 1.67006
ZMPSTE24 zinc metallopeptidase STE24 1.66962
PRR14 proline rich 14 1.66746
RABEPK Rab9 effector protein with kelch motifs 1.66482
SERHL2 serine hydrolase-like 2 1.66395
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.66358
ZNF548 zinc finger protein 548 1.65881
CTTNBP2NL CTTNBP2 N-terminal like 1.65873
CDC27 cell division cycle 27 1.65629
BMP6 bone morphogenetic protein 6 1.65397
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.6526
EPB41 erythrocyte membrane protein band 4.1 1.65056
LY6G5C lymphocyte antigen 6 complex, locus G5C 1.64916
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.64833
TMEM19 transmembrane protein 19 1.64625
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 1.64448
PTK7 protein tyrosine kinase 7 (inactive) 1.64401
UNC13B unc-13 homolog B (C. elegans) 1.6436
LINC00599 long intergenic non-protein coding RNA 599 1.6427
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.64209
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.63908
FDX1 ferredoxin 1 1.63823
UBAC1 UBA domain containing 1 1.6379
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.63755
TTC6 tetratricopeptide repeat domain 6 1.63714
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.6364
RHOH ras homolog family member H 1.6356
ZNF552 zinc finger protein 552 1.63384
RPP40 ribonuclease P/MRP 40kDa subunit 1.63361
LPAR2 lysophosphatidic acid receptor 2 1.62905
USF2 upstream transcription factor 2, c-fos interacting 1.62728
ZNF787 zinc finger protein 787 1.62643
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.62248
PTCD3 pentatricopeptide repeat domain 3 1.62189
CCDC92 coiled-coil domain containing 92 1.62149
ZDHHC18 zinc finger, DHHC-type containing 18 1.61772
SRM spermidine synthase 1.61687
GLOD4 glyoxalase domain containing 4 1.61621
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 1.61266
SCCPDH saccharopine dehydrogenase (putative) 1.61089
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 1.60791
KDM5A lysine (K)-specific demethylase 5A 1.60571
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1.60499
EIF4H eukaryotic translation initiation factor 4H 1.60463
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 1.60353
GPBAR1 G protein-coupled bile acid receptor 1 1.60187
FXR2 fragile X mental retardation, autosomal homolog 2 1.60121
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.59635
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.59457
GJD2 gap junction protein, delta 2, 36kDa 1.59303
ZNF230 zinc finger protein 230 1.59072
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 1.58901
SHPK sedoheptulokinase 1.58878
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 1.58862
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 1.58844
CPPED1 calcineurin-like phosphoesterase domain containing 1 1.5879
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.58765
PLA2G12A phospholipase A2, group XIIA 1.58418
TMEM59 transmembrane protein 59 1.58231
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 1.58133
FGF5 fibroblast growth factor 5 1.57991
CLCN4 chloride channel, voltage-sensitive 4 1.57871
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1.5779
NCLN nicalin 1.57493
CTNNBL1 catenin, beta like 1 1.57378
FOSL2 FOS-like antigen 2 1.57334
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 1.57055
TPT1 tumor protein, translationally-controlled 1 1.56968
LYPLA2 lysophospholipase II 1.56913
SSR1 signal sequence receptor, alpha 1.5686
ZNF490 zinc finger protein 490 1.5685
PDCD10 programmed cell death 10 1.56708
C14ORF119 chromosome 14 open reading frame 119 1.56432
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.56422
MRPS7 mitochondrial ribosomal protein S7 1.56322
TMOD4 tropomodulin 4 (muscle) 1.56289
SNX4 sorting nexin 4 1.56248
MBD2 methyl-CpG binding domain protein 2 1.56238
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 1.558
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 1.55733
BYSL bystin-like 1.55588
SYP synaptophysin 1.54997
SRRT serrate, RNA effector molecule 1.54988
MICU2 mitochondrial calcium uptake 2 1.54805
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.54466
ZMAT2 zinc finger, matrin-type 2 1.54403
CYB5R3 cytochrome b5 reductase 3 1.54394
SNX16 sorting nexin 16 1.543
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.53935
GOLGB1 golgin B1 1.53697
LYPLAL1 lysophospholipase-like 1 1.53688
SLTM SAFB-like, transcription modulator 1.53624
TTPAL tocopherol (alpha) transfer protein-like 1.53568
PHAX phosphorylated adaptor for RNA export 1.53411
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1.53204
FBXO10 F-box protein 10 1.52992
TM7SF3 transmembrane 7 superfamily member 3 1.5295
C6ORF106 chromosome 6 open reading frame 106 1.52708
ZNF286A zinc finger protein 286A 1.52678
OSR1 odd-skipped related transciption factor 1 1.52623
FAM20B family with sequence similarity 20, member B 1.52574
DEDD death effector domain containing 1.5254
SCAF8 SR-related CTD-associated factor 8 1.5222
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.52218
SCRN3 secernin 3 1.5207
TARBP1 TAR (HIV-1) RNA binding protein 1 1.52055
FAM49B family with sequence similarity 49, member B 1.51992
MRPL57 mitochondrial ribosomal protein L57 1.51589

decreased expression

Symbol Name Standardized Value
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -3.57909
UVRAG UV radiation resistance associated -3.50717
RPS13 ribosomal protein S13 -3.48675
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.28804
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -3.27748
RBBP9 retinoblastoma binding protein 9 -3.11849
BTBD10 BTB (POZ) domain containing 10 -2.98291
CHMP1B charged multivesicular body protein 1B -2.96809
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.93821
MTFR1L mitochondrial fission regulator 1-like -2.92361
TSSC1 tumor suppressing subtransferable candidate 1 -2.91639
NLGN1 neuroligin 1 -2.84006
DENND4B DENN/MADD domain containing 4B -2.80911
DIABLO diablo, IAP-binding mitochondrial protein -2.80398
FBXO22 F-box protein 22 -2.75589
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.75411
LIG3 ligase III, DNA, ATP-dependent -2.71674
LAMB2 laminin, beta 2 (laminin S) -2.67186
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 -2.61982
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -2.58242
FEN1 flap structure-specific endonuclease 1 -2.57568
RPS9 ribosomal protein S9 -2.56418
RABL3 RAB, member of RAS oncogene family-like 3 -2.5348
HADH hydroxyacyl-CoA dehydrogenase -2.51778
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 -2.51665
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -2.50534
EXOC1 exocyst complex component 1 -2.49308
PPAP2A phosphatidic acid phosphatase type 2A -2.47546
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 -2.44822
PARVG parvin, gamma -2.44079
VRK3 vaccinia related kinase 3 -2.43527
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -2.43463
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.43247
DYM dymeclin -2.41193
CACUL1 CDK2-associated, cullin domain 1 -2.38724
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -2.38466
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -2.38453
RAB14 RAB14, member RAS oncogene family -2.38172
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.37254
FGD3 FYVE, RhoGEF and PH domain containing 3 -2.36931
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -2.35538
GTF3A general transcription factor IIIA -2.35205
MRFAP1 Morf4 family associated protein 1 -2.34928
ABI2 abl-interactor 2 -2.34924
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -2.34559
C19ORF12 chromosome 19 open reading frame 12 -2.34304
MASP2 mannan-binding lectin serine peptidase 2 -2.33068
C6ORF47 chromosome 6 open reading frame 47 -2.32351
UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 -2.31135
CREM cAMP responsive element modulator -2.31077
FLOT1 flotillin 1 -2.30726
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) -2.29554
TBC1D13 TBC1 domain family, member 13 -2.2929
MSN moesin -2.28653
SENP5 SUMO1/sentrin specific peptidase 5 -2.27736
ZBTB34 zinc finger and BTB domain containing 34 -2.27713
C7ORF25 chromosome 7 open reading frame 25 -2.27413
APOE apolipoprotein E -2.23608
FAM214B family with sequence similarity 214, member B -2.23326
XPO5 exportin 5 -2.23171
MEIS1 Meis homeobox 1 -2.22669
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -2.21292
OLFM1 olfactomedin 1 -2.21202
AAK1 AP2 associated kinase 1 -2.21159
C12ORF4 chromosome 12 open reading frame 4 -2.20867
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.19897
PON2 paraoxonase 2 -2.19688
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.19125
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.18897
R3HDM4 R3H domain containing 4 -2.18588
MRPL52 mitochondrial ribosomal protein L52 -2.18215
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -2.18129
GID4 GID complex subunit 4 -2.17059
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -2.16902
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -2.16476
AAGAB alpha- and gamma-adaptin binding protein -2.15666
PF4V1 platelet factor 4 variant 1 -2.14896
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.146
HDGFRP3 hepatoma-derived growth factor, related protein 3 -2.14136
CDR2L cerebellar degeneration-related protein 2-like -2.13979
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -2.11671
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.11566
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.11187
TMEM194B transmembrane protein 194B -2.10789
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.10468
SCAPER S-phase cyclin A-associated protein in the ER -2.09465
DESI1 desumoylating isopeptidase 1 -2.09307
TAGAP T-cell activation RhoGTPase activating protein -2.09202
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.09098
TSC2 tuberous sclerosis 2 -2.08869
C11ORF54 chromosome 11 open reading frame 54 -2.08857
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -2.08329
FAM107A family with sequence similarity 107, member A -2.07638
CEP164 centrosomal protein 164kDa -2.06728
ACTG2 actin, gamma 2, smooth muscle, enteric -2.06354
COMMD5 COMM domain containing 5 -2.06149
RBM23 RNA binding motif protein 23 -2.06142
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -2.05927
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.04915
ULK3 unc-51 like kinase 3 -2.04234
BOK BCL2-related ovarian killer -2.03431
UBAP2L ubiquitin associated protein 2-like -2.03085
PDE9A phosphodiesterase 9A -2.02159
KLF13 Kruppel-like factor 13 -2.01228
CORO1C coronin, actin binding protein, 1C -2.00718
SLC25A38 solute carrier family 25, member 38 -2.00538
CDADC1 cytidine and dCMP deaminase domain containing 1 -2.00365
MRPL33 mitochondrial ribosomal protein L33 -2.00124
ACVR1B activin A receptor, type IB -1.99632
NUP153 nucleoporin 153kDa -1.99547
SERF1A small EDRK-rich factor 1A (telomeric) -1.99095
UBE2C ubiquitin-conjugating enzyme E2C -1.98785
FNBP1L formin binding protein 1-like -1.9869
ZBTB47 zinc finger and BTB domain containing 47 -1.97942
TRIM47 tripartite motif containing 47 -1.97723
DHCR24 24-dehydrocholesterol reductase -1.97464
ATG13 autophagy related 13 -1.97114
NEK6 NIMA-related kinase 6 -1.9711
NAGA N-acetylgalactosaminidase, alpha- -1.97046
THAP10 THAP domain containing 10 -1.96694
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -1.96405
LOXL4 lysyl oxidase-like 4 -1.96368
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -1.96267
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial -1.95973
TMEM14B transmembrane protein 14B -1.95555
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.95343
RAX2 retina and anterior neural fold homeobox 2 -1.95224
CXXC5 CXXC finger protein 5 -1.95127
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -1.94887
CDK6 cyclin-dependent kinase 6 -1.93714
EPDR1 ependymin related 1 -1.93391
ZBTB20 zinc finger and BTB domain containing 20 -1.9311
LRRC16A leucine rich repeat containing 16A -1.92389
HEBP1 heme binding protein 1 -1.9155
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -1.91529
ELP4 elongator acetyltransferase complex subunit 4 -1.91486
METRN meteorin, glial cell differentiation regulator -1.90738
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -1.90702
SRPK1 SRSF protein kinase 1 -1.89873
STX8 syntaxin 8 -1.88992
TDGF1 teratocarcinoma-derived growth factor 1 -1.88587
HIPK2 homeodomain interacting protein kinase 2 -1.88469
CAMTA1 calmodulin binding transcription activator 1 -1.88372
TMEM254 transmembrane protein 254 -1.88318
FGD6 FYVE, RhoGEF and PH domain containing 6 -1.8815
FXR1 fragile X mental retardation, autosomal homolog 1 -1.88058
BSDC1 BSD domain containing 1 -1.87913
LIFR leukemia inhibitory factor receptor alpha -1.87644
RFC1 replication factor C (activator 1) 1, 145kDa -1.87478
ZC3H15 zinc finger CCCH-type containing 15 -1.87216
PRNP prion protein -1.86848
ASF1A anti-silencing function 1A histone chaperone -1.86606
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.86573
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -1.86418
HOXB4 homeobox B4 -1.86413
RSL24D1 ribosomal L24 domain containing 1 -1.86377
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 -1.86361
TOR1AIP2 torsin A interacting protein 2 -1.86322
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -1.86312
CCND2 cyclin D2 -1.8629
TNRC6C trinucleotide repeat containing 6C -1.85714
RPS3 ribosomal protein S3 -1.85242
RUFY1 RUN and FYVE domain containing 1 -1.85229
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -1.84688
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -1.84667
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.84121
ZNF691 zinc finger protein 691 -1.83684
BFAR bifunctional apoptosis regulator -1.83628
MYNN myoneurin -1.83459
CGN cingulin -1.83458
YEATS4 YEATS domain containing 4 -1.83384
TMED4 transmembrane emp24 protein transport domain containing 4 -1.83104
PKNOX2 PBX/knotted 1 homeobox 2 -1.8273
HACD1 3-hydroxyacyl-CoA dehydratase 1 -1.82379
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -1.82296
RAN RAN, member RAS oncogene family -1.8219
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -1.81981
TMEM138 transmembrane protein 138 -1.81662
SESN2 sestrin 2 -1.81302
PEPD peptidase D -1.81201
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -1.81149
BLCAP bladder cancer associated protein -1.81091
MPHOSPH9 M-phase phosphoprotein 9 -1.80931
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D -1.80644
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -1.80384
CCDC134 coiled-coil domain containing 134 -1.80276
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -1.7989
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.79585
MARVELD1 MARVEL domain containing 1 -1.79214
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -1.79082
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.78911
MAGT1 magnesium transporter 1 -1.78558
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -1.78396
ZNRD1 zinc ribbon domain containing 1 -1.78281
GOPC golgi-associated PDZ and coiled-coil motif containing -1.78263
TMEM242 transmembrane protein 242 -1.77819
CEP89 centrosomal protein 89kDa -1.77641
KLF3 Kruppel-like factor 3 (basic) -1.77587
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -1.77154
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 -1.7695
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase -1.76941
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 -1.76414
MRPS25 mitochondrial ribosomal protein S25 -1.76361
ZNF629 zinc finger protein 629 -1.76342
RPUSD4 RNA pseudouridylate synthase domain containing 4 -1.76322
MBOAT7 membrane bound O-acyltransferase domain containing 7 -1.76299
KIF3B kinesin family member 3B -1.76209
PRAM1 PML-RARA regulated adaptor molecule 1 -1.76035
CXORF21 chromosome X open reading frame 21 -1.75652
YARS tyrosyl-tRNA synthetase -1.75607
OIP5-AS1 OIP5 antisense RNA 1 -1.75559
SNX5 sorting nexin 5 -1.75225
PKI55 DKFZp434H1419 -1.752
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -1.75037
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -1.75023
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -1.74842
GPSM3 G-protein signaling modulator 3 -1.74785
CCNB1 cyclin B1 -1.74633
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 -1.74463
AKIRIN2 akirin 2 -1.74411
TM9SF4 transmembrane 9 superfamily protein member 4 -1.74378
PIP prolactin-induced protein -1.74295
BOLA1 bolA family member 1 -1.74253
URM1 ubiquitin related modifier 1 -1.74028
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 -1.73853
TNPO1 transportin 1 -1.73801
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -1.73402
NANS N-acetylneuraminic acid synthase -1.73115
LZTR1 leucine-zipper-like transcription regulator 1 -1.7298
PUS7 pseudouridylate synthase 7 (putative) -1.72883
EI24 etoposide induced 2.4 -1.72841
FMN2 formin 2 -1.7271
RGS3 regulator of G-protein signaling 3 -1.72541
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -1.72312
TSKU tsukushi, small leucine rich proteoglycan -1.72215
TRIM39 tripartite motif containing 39 -1.72174
CCNYL1 cyclin Y-like 1 -1.7215
FAM63B family with sequence similarity 63, member B -1.72025
BAK1 BCL2-antagonist/killer 1 -1.71992
TAPT1 transmembrane anterior posterior transformation 1 -1.71829
CHD4 chromodomain helicase DNA binding protein 4 -1.71428
TRAPPC13 trafficking protein particle complex 13 -1.712
WASF2 WAS protein family, member 2 -1.71088
HMOX2 heme oxygenase 2 -1.70912
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -1.7087
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma -1.70847
TMED5 transmembrane emp24 protein transport domain containing 5 -1.70809
AK4 adenylate kinase 4 -1.70236
LUC7L2 LUC7-like 2 (S. cerevisiae) -1.69694
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -1.69653
HSBP1 heat shock factor binding protein 1 -1.69395
KIAA0141 KIAA0141 -1.69347
PHB2 prohibitin 2 -1.6926
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -1.68889
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -1.68014
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -1.6799
PBX1 pre-B-cell leukemia homeobox 1 -1.67501
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.67489
TEX2 testis expressed 2 -1.6708
SNX24 sorting nexin 24 -1.67049
MTCH1 mitochondrial carrier 1 -1.66957
PHF20 PHD finger protein 20 -1.66888
NT5C3B 5'-nucleotidase, cytosolic IIIB -1.66801
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -1.6617
TTLL7 tubulin tyrosine ligase-like family member 7 -1.66073
NEUROG1 neurogenin 1 -1.65937
ZNF664 zinc finger protein 664 -1.65732
SH3GLB1 SH3-domain GRB2-like endophilin B1 -1.65432
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -1.65426
IGF2R insulin-like growth factor 2 receptor -1.65288
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 -1.65258
CCNB2 cyclin B2 -1.65205
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -1.65088
PTCD2 pentatricopeptide repeat domain 2 -1.6502
ZBTB25 zinc finger and BTB domain containing 25 -1.64886
MRPS10 mitochondrial ribosomal protein S10 -1.6474
UFSP2 UFM1-specific peptidase 2 -1.64574
ZNF418 zinc finger protein 418 -1.64564
CTSC cathepsin C -1.6438
NUP160 nucleoporin 160kDa -1.64355
WEE1 WEE1 G2 checkpoint kinase -1.63738
KRT31 keratin 31, type I -1.63669
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -1.63537
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -1.63532
COL8A2 collagen, type VIII, alpha 2 -1.63235
NSUN7 NOP2/Sun domain family, member 7 -1.63171
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -1.63022
KLHL22 kelch-like family member 22 -1.62924
NFIB nuclear factor I/B -1.62889
CEP85 centrosomal protein 85kDa -1.6277
GMEB2 glucocorticoid modulatory element binding protein 2 -1.62715
TUBA1C tubulin, alpha 1c -1.62712
PER1 period circadian clock 1 -1.62543
SH2B3 SH2B adaptor protein 3 -1.62287
METTL18 methyltransferase like 18 -1.62067
TMEM8A transmembrane protein 8A -1.62039
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -1.61912
DHRS4-AS1 DHRS4 antisense RNA 1 -1.61548
KIAA0922 KIAA0922 -1.61478
PCCB propionyl CoA carboxylase, beta polypeptide -1.61377