TIMELESS Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description timeless circadian clock|The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 8914)
External Link http://www.ncbi.nlm.nih.gov/gene/8914
Similar Terms
Downloads & Tools

Genes

33 interacting proteins for TIMELESS from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BCLAF1 BCL2-associated transcription factor 1
CHEK1 checkpoint kinase 1
CLOCK clock circadian regulator
CLSPN claspin
CRY1 cryptochrome circadian clock 1
CRY2 cryptochrome circadian clock 2
FKBP3 FK506 binding protein 3, 25kDa
NRF1 nuclear respiratory factor 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
PCNA proliferating cell nuclear antigen
PER1 period circadian clock 1
PER2 period circadian clock 2
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
SFN stratifin
SP1 Sp1 transcription factor
SUMO2 small ubiquitin-like modifier 2
TF transferrin
TIPIN TIMELESS interacting protein
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBC ubiquitin C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZSCAN1 zinc finger and SCAN domain containing 1