TIRAP Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description toll-interleukin 1 receptor (TIR) domain containing adaptor protein|The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 114609)
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Genes

388 genes differentially expressed following the TIRAP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 2.72792
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.72792
LRRC38 leucine rich repeat containing 38 2.72792
TTLL2 tubulin tyrosine ligase-like family member 2 2.72792
TUBB tubulin, beta class I 2.72792
ACRBP acrosin binding protein 2.72792
FAM186A family with sequence similarity 186, member A 2.72792
TNC tenascin C 2.72792
NUTM2D NUT family member 2D 2.72792
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.72792
ZNF98 zinc finger protein 98 2.72792
SYCP1 synaptonemal complex protein 1 2.72792
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.72792
CROCC ciliary rootlet coiled-coil, rootletin 2.72792
C18ORF63 chromosome 18 open reading frame 63 2.72792
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.72792
RNF7 ring finger protein 7 2.72792
POPDC2 popeye domain containing 2 2.72792
SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 2.72792
LDLRAD2 low density lipoprotein receptor class A domain containing 2 2.72792
LHX1 LIM homeobox 1 2.72792
CFAP141 cilia and flagella associated protein 141 2.72792
GPR78 G protein-coupled receptor 78 2.72792
CPNE8-AS1 CPNE8 antisense RNA 1 2.72792
BTBD16 BTB (POZ) domain containing 16 2.72792
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 2.72792
TAL2 T-cell acute lymphocytic leukemia 2 2.6991
RRAD Ras-related associated with diabetes 2.6991
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 2.6991
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.6991
IZUMO3 IZUMO family member 3 2.6991
HES4 hes family bHLH transcription factor 4 2.6991
PMCH pro-melanin-concentrating hormone 2.6991
AKR1C2 aldo-keto reductase family 1, member C2 2.6991
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 2.6991
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 2.6991
ALOX15 arachidonate 15-lipoxygenase 2.6991
SLC46A2 solute carrier family 46, member 2 2.6991
IGFL3 IGF-like family member 3 2.6991
GNLY granulysin 2.6991
SPINK4 serine peptidase inhibitor, Kazal type 4 2.6991
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.6991
UMOD uromodulin 2.6991
GJB3 gap junction protein, beta 3, 31kDa 2.6991
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.6991
FAM9B family with sequence similarity 9, member B 2.6991
GPR101 G protein-coupled receptor 101 2.6991
TRIM15 tripartite motif containing 15 2.6991
CORO6 coronin 6 2.6991
VCX variable charge, X-linked 2.6991
CBLIF cobalamin binding intrinsic factor 2.6991
HMX1 H6 family homeobox 1 2.6991
KDM5A lysine (K)-specific demethylase 5A 2.6991
COL15A1 collagen, type XV, alpha 1 2.6991
CCDC38 coiled-coil domain containing 38 2.6991
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.6991
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 2.6991
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.6991
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.6991
NMUR2 neuromedin U receptor 2 2.6991
MYCT1 myc target 1 2.6991
FAM181A family with sequence similarity 181, member A 2.6991
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 2.6991
GYS2 glycogen synthase 2 (liver) 2.6991
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.6991
SPMIP1 sperm microtubule inner protein 1 2.6991
CLDN14 claudin 14 2.6991
ALX3 ALX homeobox 3 2.6991
PLN phospholamban 2.6991
RD3 retinal degeneration 3 2.6991
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.6991
MROH5 maestro heat-like repeat family member 5 2.6991
CCDC88C coiled-coil domain containing 88C 2.6991
GDF6 growth differentiation factor 6 2.6991
SLC68A1 solute carrier family 68 member 1 2.6991
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 2.6991
SPATS1 spermatogenesis associated, serine-rich 1 2.6991
ASDURF ASNSD1 upstream open reading frame 2.6991
SMIM41 small integral membrane protein 41 2.6991
SMIM32 small integral membrane protein 32 2.6991
FAM240A family with sequence similarity 240 member A 2.6991
CFAP97D2 CFAP97 domain containing 2 2.6991
CD8B2 CD8b2 molecule 2.6991
H4C3 H4 clustered histone 3 2.6991
SEPTIN12 septin 12 2.6991
TENT5D terminal nucleotidyltransferase 5D 2.6991
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.6991
JAML junction adhesion molecule like 2.6991
CCN6 cellular communication network factor 6 2.6991
RBM44 RNA binding motif protein 44 2.6991
SAA4 serum amyloid A4, constitutive 2.6991
ATP13A5 ATPase type 13A5 2.6991
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 2.6991
PRB1 proline-rich protein BstNI subfamily 1 2.6991
SRL sarcalumenin 2.6991
SBK2 SH3 domain binding kinase family, member 2 2.6991
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.6991
NAPSA napsin A aspartic peptidase 2.6991
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.6991
TXLNB taxilin beta 2.6991
NKAPL NFKB activating protein-like 2.6991
LOC124905976 uncharacterized LOC124905976 2.6991
ARL5C ADP-ribosylation factor-like 5C 2.6991
PCDHB11 protocadherin beta 11 2.6991
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 2.6991
CLDN23 claudin 23 2.6991
CCR9 chemokine (C-C motif) receptor 9 2.6991
FOXI2 forkhead box I2 2.6991
C1QL4 complement component 1, q subcomponent-like 4 2.6991
ZIC4 Zic family member 4 2.6991
CATSPER3 cation channel, sperm associated 3 2.6991
AXDND1 axonemal dynein light chain domain containing 1 2.6991
DAO D-amino-acid oxidase 2.6991
CHRD chordin 2.6991
ASB15 ankyrin repeat and SOCS box containing 15 2.6991
SPATA4 spermatogenesis associated 4 2.6991
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 2.6991
SOWAHA sosondowah ankyrin repeat domain family member A 2.6991
ANKRD53 ankyrin repeat domain 53 2.6991
SOSTDC1 sclerostin domain containing 1 2.6991
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 2.6991
RIPPLY2 ripply transcriptional repressor 2 2.6991
ERICH4 glutamate-rich 4 2.6991
NOL4L nucleolar protein 4-like 2.6991
TPPP3 tubulin polymerization-promoting protein family member 3 2.6991
SMIM17 small integral membrane protein 17 2.6991
SMYD1 SET and MYND domain containing 1 2.6991
GSTA1 glutathione S-transferase alpha 1 2.6991
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.6991
MORN5 MORN repeat containing 5 2.6991
FNDC5 fibronectin type III domain containing 5 2.6991
GFI1B growth factor independent 1B transcription repressor 2.6991
MYF5 myogenic factor 5 2.6991
CCL27 chemokine (C-C motif) ligand 27 2.6991
DAAM1 dishevelled associated activator of morphogenesis 1 2.6991
LCT lactase 2.6991
CRHR1 corticotropin releasing hormone receptor 1 2.6991
DEFB107B defensin, beta 107B 2.6991
LCN2 lipocalin 2 2.6991
LCN1 lipocalin 1 2.6991
F11 coagulation factor XI 2.6991
MKRN3 makorin ring finger protein 3 2.6991
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.6991
C16ORF78 chromosome 16 open reading frame 78 2.6991
LMOD2 leiomodin 2 (cardiac) 2.6991
BCO1 beta-carotene oxygenase 1 2.6991
RGSL1 regulator of G-protein signaling like 1 2.6991
GP2 glycoprotein 2 (zymogen granule membrane) 2.6991
SHOX2 short stature homeobox 2 2.6991
TTC16 tetratricopeptide repeat domain 16 2.6991
SLC22A24 solute carrier family 22, member 24 2.6991
EFCAB9 EF-hand calcium binding domain 9 2.6991
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.6991
POM121 POM121 transmembrane nucleoporin 2.6991
CRHBP corticotropin releasing hormone binding protein 2.6991
TEX26 testis expressed 26 2.6991
SEZ6L seizure related 6 homolog (mouse)-like 2.6991
UPK1A uroplakin 1A 2.6991
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.6991
AMDHD1 amidohydrolase domain containing 1 2.6991
NELL1 NEL-like 1 (chicken) 2.6991
SYTL1 synaptotagmin-like 1 2.6991
C11ORF91 chromosome 11 open reading frame 91 2.6991
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.6991
TMEM88 transmembrane protein 88 2.6991
LPA lipoprotein, Lp(a) 2.6991
NLRP6 NLR family, pyrin domain containing 6 2.6991
SNAI2 snail family zinc finger 2 2.6991
NLRP14 NLR family, pyrin domain containing 14 2.6991
GRM6 glutamate receptor, metabotropic 6 2.6991
NRSN1 neurensin 1 2.6991
EYA4 EYA transcriptional coactivator and phosphatase 4 2.6991
CD226 CD226 molecule 2.6991
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.6991
NLRP1 NLR family, pyrin domain containing 1 2.6991
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.6991
ETV3L ets variant 3-like 2.6991
POTEJ POTE ankyrin domain family, member J 2.6991
PENK proenkephalin 2.6991
AMER2 APC membrane recruitment protein 2 2.6991
VTCN1 V-set domain containing T cell activation inhibitor 1 2.6991
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.6991
NT5C1B 5'-nucleotidase, cytosolic IB 2.6991
PRRX1 paired related homeobox 1 2.6991
KIF4A kinesin family member 4A 2.6991
ZMYND12 zinc finger, MYND-type containing 12 2.6991
CTSW cathepsin W 2.6991
CTSS cathepsin S 2.6991
ITPKA inositol-trisphosphate 3-kinase A 2.6991
CNR2 cannabinoid receptor 2 (macrophage) 2.6991
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.6991
SH2D1B SH2 domain containing 1B 2.6991
SLC38A3 solute carrier family 38, member 3 2.6991
APOL6 apolipoprotein L, 6 2.6991
TLN1 talin 1 2.63199
LRRC8A leucine rich repeat containing 8 family, member A 2.61864
KRT7 keratin 7, type II 2.61864
CMKLR1 chemerin chemokine-like receptor 1 2.61463
BMP8A bone morphogenetic protein 8a 2.61463
SMYD5 SMYD family member 5 2.60497
GMCL1 germ cell-less, spermatogenesis associated 1 2.60221
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.56311
CCDC28B coiled-coil domain containing 28B 2.55939
WEE1 WEE1 G2 checkpoint kinase 2.55603
ORAI3 ORAI calcium release-activated calcium modulator 3 2.55032
HSBP1L1 heat shock factor binding protein 1-like 1 2.54367
GHRHR growth hormone releasing hormone receptor 2.54367
RRM2 ribonucleotide reductase M2 2.54205
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 2.51432
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.50819
ZNF322 zinc finger protein 322 2.47796
NSG2 neuronal vesicle trafficking associated 2 2.399
CNTNAP1 contactin associated protein 1 2.399
SPMIP2 sperm microtubule inner protein 2 2.399
MYEF2 myelin expression factor 2 2.391
TMEM221 transmembrane protein 221 2.34766
MUC16 mucin 16, cell surface associated 2.34412
PTK2B protein tyrosine kinase 2 beta 2.33701
PLCD3 phospholipase C, delta 3 2.31637
ZNF593 zinc finger protein 593 2.31553
ARV1 ARV1 homolog (S. cerevisiae) 2.30934
PCNP PEST proteolytic signal containing nuclear protein 2.30371
NID1 nidogen 1 2.29741
COPS7B COP9 signalosome subunit 7B 2.28698
KPNA3 karyopherin alpha 3 (importin alpha 4) 2.28649
SRSF12 serine/arginine-rich splicing factor 12 2.26853
ZFAND6 zinc finger, AN1-type domain 6 2.26184
RECQL5 RecQ protein-like 5 2.24962
KCNK6 potassium channel, two pore domain subfamily K, member 6 2.24037
SUMO1 small ubiquitin-like modifier 1 2.23738
ATF7IP2 activating transcription factor 7 interacting protein 2 2.23179
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 2.21973
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.21973
FAM227A family with sequence similarity 227, member A 2.21633
FAM133B family with sequence similarity 133, member B 2.21633
PTPRS protein tyrosine phosphatase, receptor type, S 2.21633
L3MBTL2 l(3)mbt-like 2 (Drosophila) 2.21633
VDAC2 voltage-dependent anion channel 2 2.20057
WDR55 WD repeat domain 55 2.19734
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.18801
RPL36 ribosomal protein L36 2.16742
ZNF461 zinc finger protein 461 2.16559
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 2.12513
NPM3 nucleophosmin/nucleoplasmin 3 2.12244
ZBED5 zinc finger, BED-type containing 5 2.12244
SEC24C SEC24 family member C 2.1147
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.1147
IGFBP5 insulin-like growth factor binding protein 5 2.1147
DCAF16 DDB1 and CUL4 associated factor 16 2.11193
LZTR1 leucine-zipper-like transcription regulator 1 2.10735
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.09582
TAFA5 TAFA chemokine like family member 5 2.09582
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 2.085
PTP4A2 protein tyrosine phosphatase type IVA, member 2 2.08363
CLBA1 clathrin binding box of aftiphilin containing 1 2.04182
SYN1 synapsin I 2.04097
SHTN1 shootin 1 2.04069
TRUB2 TruB pseudouridine (psi) synthase family member 2 2.0287
CCDC106 coiled-coil domain containing 106 2.0287

decreased expression

Symbol Name Standardized Value
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 -2.72792
C3ORF18 chromosome 3 open reading frame 18 -2.72792
TPRG1 tumor protein p63 regulated 1 -2.72792
ADAM28 ADAM metallopeptidase domain 28 -2.72792
NME8 NME/NM23 family member 8 -2.6991
SLC25A45 solute carrier family 25, member 45 -2.6991
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -2.6991
CASP4 caspase 4, apoptosis-related cysteine peptidase -2.6991
PAPPA2 pappalysin 2 -2.6991
KDM6B lysine (K)-specific demethylase 6B -2.6991
C17ORF100 chromosome 17 open reading frame 100 -2.6991
ZNF559 zinc finger protein 559 -2.6991
GCC1 GRIP and coiled-coil domain containing 1 -2.6991
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -2.6991
TPH2 tryptophan hydroxylase 2 -2.6991
POPDC3 popeye domain containing 3 -2.6991
LTB4R leukotriene B4 receptor -2.6991
NTNG2 netrin G2 -2.6991
COL12A1 collagen, type XII, alpha 1 -2.6991
CCDC169 coiled-coil domain containing 169 -2.6991
PCDHB4 protocadherin beta 4 -2.6991
BTN1A1 butyrophilin, subfamily 1, member A1 -2.6991
OVOL1 ovo-like zinc finger 1 -2.6991
FCSK fucose kinase -2.6991
MUSTN1 musculoskeletal, embryonic nuclear protein 1 -2.6991
ARMC2 armadillo repeat containing 2 -2.6991
NOXA1 NADPH oxidase activator 1 -2.6991
C1QTNF2 C1q and tumor necrosis factor related protein 2 -2.6991
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 -2.6991
CKM creatine kinase, muscle -2.6991
RHOXF1 Rhox homeobox family, member 1 -2.6991
WSCD2 WSC domain containing 2 -2.6991
TMEM229A transmembrane protein 229A -2.6991
SIX2 SIX homeobox 2 -2.6991
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -2.6991
MIMS1 mitochondrial inner membrane scaffold 1 -2.6991
C7ORF25 chromosome 7 open reading frame 25 -2.6991
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -2.6991
AKAP14 A kinase (PRKA) anchor protein 14 -2.6991
SLC46A3 solute carrier family 46, member 3 -2.6991
SAXO4 stabilizer of axonemal microtubules 4 -2.6991
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -2.6991
JMJD4 jumonji domain containing 4 -2.6991
PLAC9 placenta-specific 9 -2.6991
KRTAP5-11 keratin associated protein 5-11 -2.6991
MAOB monoamine oxidase B -2.6991
METRN meteorin, glial cell differentiation regulator -2.6991
RAB40A RAB40A, member RAS oncogene family -2.6991
TLL2 tolloid-like 2 -2.6991
DACT2 dishevelled-binding antagonist of beta-catenin 2 -2.6991
TUBA8 tubulin, alpha 8 -2.6991
CERCAM cerebral endothelial cell adhesion molecule -2.6991
SPOP speckle-type POZ protein -2.6991
FZD1 frizzled class receptor 1 -2.6991
SPATC1 spermatogenesis and centriole associated 1 -2.6991
HHIPL1 HHIP-like 1 -2.6991
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -2.68631
SNX13 sorting nexin 13 -2.62719
CIT citron rho-interacting serine/threonine kinase -2.61977
LMF2 lipase maturation factor 2 -2.61199
WHRN whirlin -2.60882
ZNF521 zinc finger protein 521 -2.59296
RPL4 ribosomal protein L4 -2.56021
CDH12 cadherin 12, type 2 (N-cadherin 2) -2.54632
OLFM3 olfactomedin 3 -2.54632
SRSF5 serine/arginine-rich splicing factor 5 -2.51907
GAL3ST4 galactose-3-O-sulfotransferase 4 -2.51907
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.51605
FAM131B family with sequence similarity 131, member B -2.50042
BBLN bublin coiled coil protein -2.4896
EGF epidermal growth factor -2.44377
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -2.44377
TAS2R20 taste receptor, type 2, member 20 -2.44377
CORO1A coronin, actin binding protein, 1A -2.44377
TBL1X transducin (beta)-like 1X-linked -2.40067
TMEM237 transmembrane protein 237 -2.399
SCG5 secretogranin V -2.391
CXXC5 CXXC finger protein 5 -2.38726
THBS4 thrombospondin 4 -2.34412
ZBTB20 zinc finger and BTB domain containing 20 -2.33782
SNW1 SNW domain containing 1 -2.33745
CCDC50 coiled-coil domain containing 50 -2.33471
CAB39 calcium binding protein 39 -2.33108
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -2.32368
KSR1 kinase suppressor of ras 1 -2.31931
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -2.30832
DCAF1 DDB1 and CUL4 associated factor 1 -2.30508
CXCL5 chemokine (C-X-C motif) ligand 5 -2.30308
ELOVL7 ELOVL fatty acid elongase 7 -2.28018
GDAP2 ganglioside induced differentiation associated protein 2 -2.27898
IRAK1 interleukin-1 receptor-associated kinase 1 -2.27898
CDCA3 cell division cycle associated 3 -2.25672
ZNF57 zinc finger protein 57 -2.23846
GPATCH4 G patch domain containing 4 -2.23084
TSPAN10 tetraspanin 10 -2.22202
TMEM26 transmembrane protein 26 -2.21973
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.21633
DERA deoxyribose-phosphate aldolase (putative) -2.21633
TINCR tissue differentiation-inducing non-protein coding RNA -2.21633
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.21633
KLF8 Kruppel-like factor 8 -2.18463
USP54 ubiquitin specific peptidase 54 -2.17355
DNM1L dynamin 1-like -2.16145
SMOC2 SPARC related modular calcium binding 2 -2.15813
MTFR1 mitochondrial fission regulator 1 -2.15472
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.15213
MEGF11 multiple EGF-like-domains 11 -2.15189
MAPK8 mitogen-activated protein kinase 8 -2.1254
ZNF678 zinc finger protein 678 -2.12474
KIF26A kinesin family member 26A -2.11143
CRAMP1 cramped chromatin regulator homolog 1 -2.11125
OBI1 ORC ubiquitin ligase 1 -2.10082
SRRM3 serine/arginine repetitive matrix 3 -2.09582
PLCB4 phospholipase C, beta 4 -2.09582
ZHX1 zinc fingers and homeoboxes 1 -2.09582
DOP1A DOP1 leucine zipper like protein A -2.09331
E2F5 E2F transcription factor 5, p130-binding -2.09331
STC2 stanniocalcin 2 -2.08312
GLRX3 glutaredoxin 3 -2.07579
SIMC1 SUMO-interacting motifs containing 1 -2.04321
TM9SF2 transmembrane 9 superfamily member 2 -2.04321
SNIP1 Smad nuclear interacting protein 1 -2.04182
AATF apoptosis antagonizing transcription factor -2.04097
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -2.04097
DYNLT2 dynein light chain Tctex-type 2 -2.03763
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.02768
TENM2 teneurin transmembrane protein 2 -2.01445
FADS3 fatty acid desaturase 3 -2.0137
WDR19 WD repeat domain 19 -2.00388