TLE3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description transducin-like enhancer of split 3|This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 7090)
External Link http://www.ncbi.nlm.nih.gov/gene/7090
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Genes

85 interacting proteins for TLE3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTG1 actin gamma 1
AES amino-terminal enhancer of split
AHCYL1 adenosylhomocysteinase-like 1
ALYREF Aly/REF export factor
ANXA1 annexin A1
APP amyloid beta (A4) precursor protein
ARCN1 archain 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
C2ORF44 chromosome 2 open reading frame 44
CCNB1 cyclin B1
CCP110 centriolar coiled coil protein 110kDa
CDK1 cyclin-dependent kinase 1
CEP97 centrosomal protein 97kDa
CNOT11 CCR4-NOT transcription complex, subunit 11
CNOT2 CCR4-NOT transcription complex, subunit 2
CNOT3 CCR4-NOT transcription complex, subunit 3
COL1A1 collagen, type I, alpha 1
COPB1 coatomer protein complex, subunit beta 1
COPG1 coatomer protein complex, subunit gamma 1
COPZ1 coatomer protein complex, subunit zeta 1
CUL4B cullin 4B
CYLD cylindromatosis (turban tumor syndrome)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DLAT dihydrolipoamide S-acetyltransferase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FAM222A family with sequence similarity 222, member A
FAM222B family with sequence similarity 222, member B
FLOT2 flotillin 2
FOXG1 forkhead box G1
GRWD1 glutamate-rich WD repeat containing 1
HDAC1 histone deacetylase 1
HINFP histone H4 transcription factor
HNF4A hepatocyte nuclear factor 4, alpha
HSPA1B heat shock 70kDa protein 1B
IGBP1 immunoglobulin (CD79A) binding protein 1
KLC1 kinesin light chain 1
KPNB1 karyopherin (importin) beta 1
LEF1 lymphoid enhancer-binding factor 1
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
NLK nemo-like kinase
PABPN1 poly(A) binding protein, nuclear 1
PASK PAS domain containing serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKLR pyruvate kinase, liver and RBC
PKM pyruvate kinase, muscle
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RBM14 RNA binding motif protein 14
RBMX RNA binding motif protein, X-linked
RNF219 ring finger protein 219
RPLP0 ribosomal protein, large, P0
RPS14 ribosomal protein S14
S100A9 S100 calcium binding protein A9
SEC24A SEC24 family member A
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIX3 SIX homeobox 3
SIX4 SIX homeobox 4
SKI SKI proto-oncogene
SMAD1 SMAD family member 1
SMAD4 SMAD family member 4
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SRXN1 sulfiredoxin 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D4 TBC1 domain family, member 4
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa
TRPS1 trichorhinophalangeal syndrome I
UBA2 ubiquitin-like modifier activating enzyme 2
UBAP2L ubiquitin associated protein 2-like
UBC ubiquitin C
UBD ubiquitin D
WDR26 WD repeat domain 26
WDR82 WD repeat domain 82
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase